Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage

Osteoarthritis and Cartilage

Volumn 18, Issue 7, 2010, Pages 992-1000

  Wei, T ^a   Kulkarni, N H ^a   Zeng, Q Q ^a   Helvering, L M ^a   Lin, X ^a   Lawrence, F ^a   Hale, L ^a   Chambers, M G ^a   Lin, C ^a   Harvey, A ^a   Ma, Y L ^a   Cain, R L ^a   Oskins, J ^a   Carozza, M A ^a   Edmondson, D D ^a   Hu, T ^a   Miles, R R ^a   Ryan, T P ^a   Onyia, J E ^a   Mitchell, P G ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Cartilage; DNA microarray; Osteoarthritis; Pathway analysis; Rat meniscal tear model

Indexed keywords

COLLAGEN; COLLAGEN TYPE 5 ALPHA1; COLLAGEN TYPE 6 ALPHA2; GENE PRODUCT; INHIBIN; INHIBIN BETA A; LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN; LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 2; MESSENGER RNA; NEUROBLASTOMA SUPPRESSION OF TUMORIGENICITY 1 PROTEIN; SERPIN PEPTIDASE INHIBITOR CLADE E 1; SERPINA1; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; ARTICULAR CARTILAGE; BONE REMODELING; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DEATH; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DNA INTEGRATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; HUMAN TISSUE; INFLAMMATION; KNEE MENISCUS RUPTURE; MALE; MICROARRAY ANALYSIS; NONHUMAN; OSTEOARTHRITIS; PATHOGENESIS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; FEMUR; HUMANS; MALE; MENISCI, TIBIAL; MICROARRAY ANALYSIS; MODELS, ANIMAL; OSTEOARTHRITIS; RATS; RATS, INBRED LEW; TIBIA;

EID: 77954218250     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.04.012     Document Type: Article

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