Mangiferin increases Nrf2 protein stability by inhibiting its ubiquitination and degradation in human HL60 myeloid leukemia cells

International Journal of Molecular Medicine

Volumn 33, Issue 5, 2014, Pages 1348-1354

  Zhao, Jie ^a   Zhang, Benping ^a   Li, Shanshan ^a   Zeng, Linglan ^a   Chen, Yan ^a   Fang, Jun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Leukemia; Mangiferin; Nuclear factor erythroid 2 related factor 2; Protein stabilization; Ubiquitination

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLOHEXIMIDE; MANGIFERIN; MESSENGER RNA; TRANSCRIPTION FACTOR NRF2; XANTHONE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG HALF LIFE; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MYELOID LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY; REAL TIME POLYMERASE CHAIN REACTION; UBIQUITINATION; WESTERN BLOTTING; DRUG EFFECTS; HL 60 CELL LINE; METABOLISM; MYELOID LEUKEMIA; SIGNAL TRANSDUCTION;

HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID; NF-E2-RELATED FACTOR 2; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION; XANTHONES;

EID: 84899556917     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1696     Document Type: Article

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