메뉴 건너뛰기




Volumn 7, Issue 1, 2010, Pages 67-75

Molecular basis of traditional chinese medicine in cancer chemoprevention

Author keywords

Chemoprevention; NF B; Nrf2 and COX 2; Traditional Chinese medicine

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SHI QUAN DA BU TANG; TRANSCRIPTION FACTOR NRF2;

EID: 77951717597     PISSN: 15701638     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016310791162794     Document Type: Review
Times cited : (72)

References (94)
  • 1
    • 33644649421 scopus 로고    scopus 로고
    • Nrf2: A potential molecular target for cancer chemoprevention by natural compounds
    • DOI 10.1089/ars.2006.8.99
    • Jeong WS, Jun M, Kong AN. Nrf2: a potential molecular target for cancer chemoprevention by natural compounds. Antioxid Redox Signal 2006; 8(1-2): 99-106. (Pubitemid 43324535)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.1-2 , pp. 99-106
    • Jeong, W.-S.1    Jun, M.2    Kong, A.-N.T.3
  • 2
    • 0033179705 scopus 로고    scopus 로고
    • Cancer chemoprevention: Future holds in multiple agents
    • DOI 10.1006/taap.1999.8721
    • Mukhtar H, Ahmad N. Cancer chemoprevention: future holds in multiple agents. Toxicol Appl Pharmacol 1999; 158(3): 207-210 (Pubitemid 29382938)
    • (1999) Toxicology and Applied Pharmacology , vol.158 , Issue.3 , pp. 207-210
    • Mukhtar, H.1    Ahmad, N.2
  • 4
    • 2442560093 scopus 로고    scopus 로고
    • Mechanisms of chemoprevention
    • Walaszek Z, Hanausek M, Slaga TJ. Mechanisms of chemoprevention. Chest 2004; 125(5 Suppl): 128S-33S.
    • (2004) Chest , vol.125 , Issue.5 SUPPL.
    • Walaszek, Z.1    Hanausek, M.2    Slaga, T.J.3
  • 5
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002; 2(1): 48-58. (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 7
    • 2142808235 scopus 로고    scopus 로고
    • Colorectal Cancer Chemoprevention - An Overview of the Science
    • DOI 10.1053/j.gastro.2004.03.002
    • Hawk ET, Umar A, Viner JL. Colorectal cancer chemoprevention-an overview of the science. Gastroenterology 2004; 126(5): 1423-1447 (Pubitemid 38552806)
    • (2004) Gastroenterology , vol.126 , Issue.5 , pp. 1423-1447
    • Hawk, E.T.1    Umar, A.2    Viner, J.L.3
  • 8
    • 65349152488 scopus 로고    scopus 로고
    • Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: An international consensus statement
    • Cuzick J, Otto F, Baron JA, et al. Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: An international consensus statement. Lancet Oncol 2009; 10(5): 501-507.
    • (2009) Lancet Oncol , vol.10 , Issue.5 , pp. 501-507
    • Cuzick, J.1    Otto, F.2    Baron, J.A.3
  • 9
    • 64249169883 scopus 로고    scopus 로고
    • A new dawn for the use of traditional Chinese medicine in cancer therapy
    • Parekh HS, Liu G, Wei MQ. A new dawn for the use of traditional Chinese medicine in cancer therapy. Mol Cancer 2009; 8: 21.
    • (2009) Mol Cancer , vol.8 , pp. 21
    • Parekh, H.S.1    Liu, G.2    Wei, M.Q.3
  • 10
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • DOI 10.1038/nature04870, PII NATURE04870
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006; 441(7092): 431-436 (Pubitemid 44050137)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 431-436
    • Karin, M.1
  • 11
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c- IAP2 to suppress caspase-8 activation
    • DOI 10.1126/science.281.5383.1680
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998; 281(5383): 1680-1683 (Pubitemid 28435585)
    • (1998) Science , vol.281 , Issue.5383 , pp. 1680-1683
    • Wang, C.-Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 12
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and rel proteins: Evolutionarily conserved mediators of immune responses
    • DOI 10.1146/annurev.immunol.16.1.225
    • Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998; 16: 225-260 (Pubitemid 28183365)
    • (1998) Annual Review of Immunology , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 13
    • 0036144763 scopus 로고    scopus 로고
    • Regulatory functions of ubiquitination in the immune system
    • DOI 10.1038/ni0102-20
    • Ben-Neriah Y. Regulatory functions of ubiquitination in the immune system. Nat Immunol 2002; 3(1): 20-26 (Pubitemid 34065613)
    • (2002) Nature Immunology , vol.3 , Issue.1 , pp. 20-26
    • Ben-Neriah, Y.1
  • 14
    • 0031027343 scopus 로고    scopus 로고
    • A role for transcription factor NF-κB in inflammation
    • DOI 10.1007/s000110050009
    • Chabot-Fletcher M. A role for transcription factor NF-kappa B in inflammation. Inflamm Res 1997; 46(1): 1-2. (Pubitemid 27068293)
    • (1997) Inflammation Research , vol.46 , Issue.1 , pp. 1-2
    • Chabot-Fletcher, M.1
  • 15
    • 51549087131 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by green tea polyphenols
    • Khan N, Mukhtar H. Multitargeted therapy of cancer by green tea polyphenols. Cancer Lett 2008; 269(2): 269-280
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 269-280
    • Khan, N.1    Mukhtar, H.2
  • 16
    • 0035451363 scopus 로고    scopus 로고
    • Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation
    • 243-268
    • Surh YJ, Chun KS, Cha HH, et al. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 2001; 480-81: 243-268
    • (2001) Mutat Res , pp. 480-481
    • Surh, Y.J.1    Chun, K.S.2    Cha, H.H.3
  • 17
    • 0030608878 scopus 로고    scopus 로고
    • Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages
    • DOI 10.1016/S0014-5793(97)01377-X, PII S001457939701377X
    • D'Acquisto F, Iuvone T, Rombola L, et al. Involvement of NF-kappaB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages. FEBS Lett 1997; 418(1-2): 175-178 (Pubitemid 27514441)
    • (1997) FEBS Letters , vol.418 , Issue.1-2 , pp. 175-178
    • D'Acquisto, F.1    Iuvone, T.2    Rombola, L.3    Sautebin, L.4    Di Rosa, M.5    Carnuccio, R.6
  • 18
    • 0027939931 scopus 로고
    • Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase
    • Xie QW, Kashiwabara Y, Nathan C. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Chem 1994; 269(7): 4705-4708 (Pubitemid 24239438)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.7 , pp. 4705-4708
    • Xie, Q.-W.1    Kashiwabara, Y.2    Nathan, C.3
  • 19
    • 76749165731 scopus 로고    scopus 로고
    • Sigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaB
    • Meunier J, Hayashi T. Sigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaB. J Pharmacol Exp Ther 2010; 332(2): 388-397
    • (2010) J Pharmacol Exp Ther , vol.332 , Issue.2 , pp. 388-397
    • Meunier, J.1    Hayashi, T.2
  • 20
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med 2006; 354(3): 270-282
    • (2006) N Engl J Med , vol.354 , Issue.3 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 21
    • 0013887614 scopus 로고
    • Mechanisms of chemical carcinogenesis: Nature of proximate carcinogens and interactions with macromolecules
    • Miller EC, Miller JA. Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules. Pharmacol Rev 1966; 18(1): 805-838
    • (1966) Pharmacol Rev , vol.18 , Issue.1 , pp. 805-838
    • Miller, E.C.1    Miller, J.A.2
  • 23
    • 0029870954 scopus 로고    scopus 로고
    • The war on cancer
    • Sporn MB. The war on cancer. Lancet 1996; 347(9012): 1377-1381
    • (1996) Lancet , vol.347 , Issue.9012 , pp. 1377-1381
    • Sporn, M.B.1
  • 24
    • 0030868098 scopus 로고    scopus 로고
    • Chemoprevention by inducers of carcinogen detoxication enzymes
    • Kensler TW. Chemoprevention by inducers of carcinogen detoxication enzymes. Environ Health Perspect 1997; 105(Suppl 4): 965-970
    • (1997) Environ Health Perspect , vol.105 , Issue.SUPPL. 4 , pp. 965-970
    • Kensler, T.W.1
  • 25
    • 0032841203 scopus 로고    scopus 로고
    • Antioxidant functions of sulforaphane: A potent inducer of phase II detoxication enzymes
    • DOI 10.1016/S0278-6915(99)00082-4, PII S0278691599000824
    • Fahey JW, Talalay P. Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol 1999; 37(9-10): 973-979 (Pubitemid 29481800)
    • (1999) Food and Chemical Toxicology , vol.37 , Issue.9-10 , pp. 973-979
    • Fahey, J.W.1    Talalay, P.2
  • 26
    • 0035870298 scopus 로고    scopus 로고
    • The cap 'n' collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes
    • McMahon M, Itoh K, Yamamoto M, et al. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res 2001; 61(8): 3299-3307 (Pubitemid 32695017)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3299-3307
    • McMahon, M.1    Itoh, K.2    Yamamoto, M.3    Chanas, S.A.4    Henderson, C.J.5    McLellan, L.I.6    Wolf, C.R.7    Cavin, C.8    Hayes, J.D.9
  • 27
    • 0037106099 scopus 로고    scopus 로고
    • Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
    • Thimmulappa RK, Mai KH, Srisuma S, et al. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res 2002; 62(18): 5196-5203 (Pubitemid 35033454)
    • (2002) Cancer Research , vol.62 , Issue.18 , pp. 5196-5203
    • Thimmulappa, R.K.1    Mai, K.H.2    Srisuma, S.3    Kensler, T.W.4    Yamamoto, M.5    Biswal, S.6
  • 28
    • 4444315787 scopus 로고    scopus 로고
    • A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway
    • Zhang Y, Gordon GB. A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway. Mol Cancer Ther 2004; 3(7): 885-893 (Pubitemid 39193771)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.7 , pp. 885-893
    • Zhang, Y.1    Gordon, G.B.2
  • 29
    • 3042748129 scopus 로고    scopus 로고
    • Multiple roles of COX-2 in tumor angiogenesis: A target for antiangiogenic therapy
    • DOI 10.1016/j.seminoncol.2004.03.040, PII S0093775404001897
    • Gately S, Li WW. Multiple roles of COX-2 in tumor angiogenesis: A target for antiangiogenic therapy. Semin Oncol 2004; 31(2 Suppl 7): 2-11. (Pubitemid 38879409)
    • (2004) Seminars in Oncology , vol.31 , Issue.SUPPL. 7 , pp. 2-11
    • Gately, S.1    Li, W.W.2
  • 30
    • 0034530889 scopus 로고    scopus 로고
    • The contributions of cyclooxygenase-2 to tumor angiogenesis
    • Gately S. The contributions of cyclooxygenase-2 to tumor angiogenesis. Cancer Metastasis Rev 2000; 19(1-2): 19-27.
    • (2000) Cancer Metastasis Rev , vol.19 , Issue.1-2 , pp. 19-27
    • Gately, S.1
  • 31
    • 56349164325 scopus 로고    scopus 로고
    • Anti-metastatic action of non-steroidal anti-inflammatory drugs
    • Hung WC. Anti-metastatic action of non-steroidal anti-inflammatory drugs. Kaohsiung J Med Sci 2008; 24(8): 392-397
    • (2008) Kaohsiung J Med Sci , vol.24 , Issue.8 , pp. 392-397
    • Hung, W.C.1
  • 32
    • 0032031438 scopus 로고    scopus 로고
    • Biochemical pharmacology of nonsteroidal anti-inflammatory drugs
    • DOI 10.1016/S0006-2952(97)00342-0, PII S0006295297003420
    • Wu KK. Biochemical pharmacology of nonsteroidal anti-inflammatory drugs. Biochem Pharmacol 1998; 55(5): 543-547 (Pubitemid 28077812)
    • (1998) Biochemical Pharmacology , vol.55 , Issue.5 , pp. 543-547
    • Wu, K.K.-Y.1
  • 33
    • 0031689543 scopus 로고    scopus 로고
    • Cyclooxygenase in biology and disease
    • Dubois RN, Abramson SB, Crofford L, et al. Cyclooxygenase in biology and disease. FASEB J 1998; 12(12): 1063-1073
    • (1998) FASEB J , vol.12 , Issue.12 , pp. 1063-1073
    • Dubois, R.N.1    Abramson, S.B.2    Crofford, L.3
  • 34
    • 4143107932 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition
    • DOI 10.1124/pr.56.3.3
    • Simmons DL, Botting RM, Hla T. Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition. Pharmacol Rev 2004; 56(3): 387-437. (Pubitemid 39096597)
    • (2004) Pharmacological Reviews , vol.56 , Issue.3 , pp. 387-437
    • Simmons, D.L.1    Botting, R.M.2    Hla, T.3
  • 35
    • 43049168293 scopus 로고    scopus 로고
    • NSAIDs and apoptosis
    • Jana NR. NSAIDs and apoptosis. Cell Mol Life Sci 2008; 65(9): 1295-1301
    • (2008) Cell Mol Life Sci , vol.65 , Issue.9 , pp. 1295-1301
    • Jana, N.R.1
  • 36
    • 0036837835 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors block cell growth, increase ceramide and inhibit cell cycle
    • DOI 10.1023/A:1020224503335
    • Kundu N, Smyth MJ, Samsel L, Fulton AM. Cyclooxygenase inhibitors block cell growth, increase ceramide and inhibit cell cycle. Breast Cancer Res Treat 2002; 76(1): 57-64. (Pubitemid 35178628)
    • (2002) Breast Cancer Research and Treatment , vol.76 , Issue.1 , pp. 57-64
    • Kundu, N.1    Smyth, M.J.2    Samsel, L.3    Fulton, A.M.4
  • 37
    • 1842583732 scopus 로고    scopus 로고
    • Cancer chemoprevention by targeting proteasomal degradation: Commentary re Dragnev KA et al, Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: Implications for combination therapy
    • Yang CS, Chin KV, Lambert JD. Cancer chemoprevention by targeting proteasomal degradation: Commentary re Dragnev KA et al, Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: Implications for combination therapy. Clin Cancer Res 2004; 10(7): 2220-2221
    • (2004) Clin Cancer Res , vol.10 , Issue.7 , pp. 2220-2221
    • Yang, C.S.1    Chin, K.V.2    Lambert, J.D.3
  • 38
    • 3142596577 scopus 로고    scopus 로고
    • Differential effects of selective COX-2 inhibitors on cell cyde regulation and proliferation of glioblastoma cell lines
    • Kardosh A, Blumenthal M, Wang WJ, Chen TC, Schonthal AH. Differential effects of selective COX-2 inhibitors on cell cycle regulation and proliferation of glioblastoma cell lines. Cancer Biol Ther 2004; 3(1): 55-62. (Pubitemid 41342419)
    • (2004) Cancer Biology and Therapy , vol.3 , Issue.1 , pp. 55-62
    • Kardosh, A.1    Blumenthal, M.2    Wang, W.J.3    Chen, T.C.4    Schonthal, A.H.5
  • 41
    • 33947511856 scopus 로고    scopus 로고
    • Uncovering novel targets for cancer chemoprevention
    • Dragnev KH, Feng Q, Ma Y, et al. Uncovering novel targets for cancer chemoprevention. Recent Results Cancer Res 2007; 174: 235-243
    • (2007) Recent Results Cancer Res , vol.174 , pp. 235-243
    • Dragnev, K.H.1    Feng, Q.2    Ma, Y.3
  • 42
    • 0030898710 scopus 로고    scopus 로고
    • Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance
    • Bush KT, Goldberg AL, Nigam SK. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance. J Biol Chem 1997; 272(14): 9086-9092
    • (1997) J Biol Chem , vol.272 , Issue.14 , pp. 9086-9092
    • Bush, K.T.1    Goldberg, A.L.2    Nigam, S.K.3
  • 43
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • DOI 10.1172/JCI200216886
    • Kaufman RJ. Orchestrating the unfolded protein response in health and disease. J Clin Invest 2002; 110(10): 1389-1398 (Pubitemid 35396907)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.10 , pp. 1389-1398
    • Kaufman, R.J.1
  • 44
    • 0035004474 scopus 로고    scopus 로고
    • Inhibitory potential of herbal medicines on human cytochrome P450-mediated oxidation: Properties of Umbelliferous or Citrus crude drugs and their relative prescriptions
    • DOI 10.1254/jjp.85.399
    • Guo LQ, Taniguchi M, Chen QY, Baba K, Yamazoe Y. Inhibitory potential of herbal medicines on human cytochrome P450-mediated oxidation: Properties of umbelliferous or citrus crude drugs and their relative prescriptions. Jpn J Pharmacol 2001; 85(4): 399-408. (Pubitemid 32421731)
    • (2001) Japanese Journal of Pharmacology , vol.85 , Issue.4 , pp. 399-408
    • Guo, L.-Q.1    Taniguchi, M.2    Chen, Q.-Y.3    Baba, K.4    Yamazoe, Y.5
  • 45
    • 0026053011 scopus 로고
    • Comparison of anti-lipid peroxidative effects of the underground parts of Notopterygium incisum and N. forbesii in mice
    • Yang XW, Gu ZM, Wang BX, Hattori M, Namba T. Comparison of anti-lipid peroxidative effects of the underground parts of Notopterygium incisum and N. forbesii in mice. Planta Med 1991; 57(5): 399-402.
    • (1991) Planta Med , vol.57 , Issue.5 , pp. 399-402
    • Yang, X.W.1    Gu, Z.M.2    Wang, B.X.3    Hattori, M.4    Namba, T.5
  • 47
    • 0030131978 scopus 로고    scopus 로고
    • Chemical constituents of Notopterygium forbesii Boiss
    • 319
    • Wang S, Wang T. Chemical constituents of Notopterygium forbesii Boiss. Zhongguo Zhong Yao Za Zhi 1996; 21(5): 295-96, 319.
    • (1996) Zhongguo Zhong Yao Za Zhi , vol.21 , Issue.5 , pp. 295-296
    • Wang, S.1    Wang, T.2
  • 48
    • 58149092025 scopus 로고    scopus 로고
    • Notopterygium forbesii boiss extract and its active constituents increase reactive species and heme oxygenase-1 in human fetal hepatocytes: Mechanisms of action
    • Tang SY, Wang H, Zhang W, Halliwell B. Notopterygium forbesii boiss extract and its active constituents increase reactive species and heme oxygenase-1 in human fetal hepatocytes: Mechanisms of action. Chem Res Toxicol 2008; 21(12): 2414-2423
    • (2008) Chem Res Toxicol , vol.21 , Issue.12 , pp. 2414-2423
    • Tang, S.Y.1    Wang, H.2    Zhang, W.3    Halliwell, B.4
  • 49
    • 68949127020 scopus 로고    scopus 로고
    • Notopterygium forbesii Boiss extract and its active constituent phenethyl ferulate attenuate pro-inflammatory responses to lipopolysaccharide in RAW 264.7 macrophages. A "protective" role for oxidative stress?
    • Tang SY, Cheah IK, Wang H, Halliwell B. Notopterygium forbesii Boiss extract and its active constituent phenethyl ferulate attenuate pro-inflammatory responses to lipopolysaccharide in RAW 264.7 macrophages. A "protective" role for oxidative stress? Chem Res Toxicol 2009; 22(8): 1473-1482
    • (2009) Chem Res Toxicol , vol.22 , Issue.8 , pp. 1473-1482
    • Tang, S.Y.1    Cheah, I.K.2    Wang, H.3    Halliwell, B.4
  • 50
    • 0027054303 scopus 로고
    • Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs
    • Zee-Cheng RK. Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs. Methods Find Exp Clin Pharmacol 1992; 14(9): 725-736
    • (1992) Methods Find Exp Clin Pharmacol , vol.14 , Issue.9 , pp. 725-736
    • Zee-Cheng, R.K.1
  • 52
    • 66549108209 scopus 로고    scopus 로고
    • Synergistic antioxidant activities of eight traditional Chinese herb pairs
    • Yang WJ, Li DP, Li JK, et al. Synergistic antioxidant activities of eight traditional Chinese herb pairs. Biol Pharm Bull 2009; 32(6): 1021-1026
    • (2009) Biol Pharm Bull , vol.32 , Issue.6 , pp. 1021-1026
    • Yang, W.J.1    Li, D.P.2    Li, J.K.3
  • 53
    • 67650992088 scopus 로고    scopus 로고
    • Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells
    • Chu Q, Hashimoto K, Satoh K, Wang Q, Sakagami H. Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells. In vivo 2009; 23(4): 537-544
    • (2009) In Vivo , vol.23 , Issue.4 , pp. 537-544
    • Chu, Q.1    Hashimoto, K.2    Satoh, K.3    Wang, Q.4    Sakagami, H.5
  • 54
    • 77951723051 scopus 로고    scopus 로고
    • An Antioxidant Phytotherapy to Rescue Neuronal Oxidative Stress
    • Epub ahead of print
    • Lin Z, Zhu D, Yan Y, et al. An Antioxidant Phytotherapy to Rescue Neuronal Oxidative Stress. Evid Based Complement Alternat Med 2008; [Epub ahead of print].
    • (2008) Evid Based Complement Alternat Med
    • Lin, Z.1    Zhu, D.2    Yan, Y.3
  • 55
    • 55949128500 scopus 로고    scopus 로고
    • Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: Quinone oxidoreductase 1 by alkylating Keap1
    • Dietz BM, Liu D, Hagos GK, et al. Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1. Chem Res Toxicol 2008; 21(10): 1939-1948.
    • (2008) Chem Res Toxicol , vol.21 , Issue.10 , pp. 1939-1948
    • Dietz, B.M.1    Liu, D.2    Hagos, G.K.3
  • 56
    • 34250358741 scopus 로고    scopus 로고
    • Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: Role of glutathione synthesis and regeneration
    • Chiu PY, Leung HY, Siu AH, et al. Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: role of glutathione synthesis and regeneration. Planta Med 2007; 73(2): 134-141
    • (2007) Planta Med , vol.73 , Issue.2 , pp. 134-141
    • Chiu, P.Y.1    Leung, H.Y.2    Siu, A.H.3
  • 57
    • 33744804557 scopus 로고    scopus 로고
    • Danshen: What every cardiologist should know about this Chinese herbal drug
    • Cheng TO. Danshen: what every cardiologist should know about this Chinese herbal drug. Int J Cardiol 2006; 110(3): 411-412
    • (2006) Int J Cardiol , vol.110 , Issue.3 , pp. 411-412
    • Cheng, T.O.1
  • 58
    • 27844511101 scopus 로고    scopus 로고
    • Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
    • DOI 10.1177/0091270005282630
    • Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol 2005; 45(12): 1345-1359 (Pubitemid 41643896)
    • (2005) Journal of Clinical Pharmacology , vol.45 , Issue.12 , pp. 1345-1359
    • Zhou, L.1    Zuo, Z.2    Chow, M.S.S.3
  • 59
    • 70350185420 scopus 로고    scopus 로고
    • Preventive effects of a purified extract isolated from Salvia miltiorrhiza enriched with tanshinone I, tanshinone IIA and cryptotanshinone on hepatocyte in jury in vitro and in vivo
    • Park EJ, Zhao YZ, Kim YC, Sohn DH. Preventive effects of a purified extract isolated from Salvia miltiorrhiza enriched with tanshinone I, tanshinone IIA and cryptotanshinone on hepatocyte in jury in vitro and in vivo. Food Chem Toxicol 2009; 47(11): 2742-2748
    • (2009) Food Chem Toxicol , vol.47 , Issue.11 , pp. 2742-2748
    • Park, E.J.1    Zhao, Y.Z.2    Kim, Y.C.3    Sohn, D.H.4
  • 60
    • 61349154148 scopus 로고    scopus 로고
    • The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS
    • Fan GW, Gao XM, Wang H, et al. The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS. J Steroid Biochem Mol Biol 2009; 113(3-5): 275-280
    • (2009) J Steroid Biochem Mol Biol , vol.113 , Issue.3-5 , pp. 275-280
    • Fan, G.W.1    Gao, X.M.2    Wang, H.3
  • 61
    • 0026309074 scopus 로고
    • Cytotoxic activities of tanshinones against human carcinoma cell lines
    • Wu WL, Chang WL, Chen CF. Cytotoxic activities of tanshinones against human carcinoma cell lines. Am J Chin Med 1991; 19(3-4): 207-216
    • (1991) Am J Chin Med , vol.19 , Issue.3-4 , pp. 207-216
    • Wu, W.L.1    Chang, W.L.2    Chen, C.F.3
  • 62
    • 0344197546 scopus 로고    scopus 로고
    • In vitro cytotoxicity of tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells
    • Mosaddik MA. In vitro cytotoxicity of tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells. Phytomedicine 2003; 10(8): 682-685
    • (2003) Phytomedicine , vol.10 , Issue.8 , pp. 682-685
    • Mosaddik, M.A.1
  • 65
    • 52949101728 scopus 로고    scopus 로고
    • Growth inhibition and apoptosis induction by tanshinone IIA in human colon adenocarcinoma cells
    • Su CC, Chen GW, Kang JC, Chan MH. Growth inhibition and apoptosis induction by tanshinone IIA in human colon adenocarcinoma cells. Planta Med 2008; 74(11): 1357-1362
    • (2008) Planta Med , vol.74 , Issue.11 , pp. 1357-1362
    • Su, C.C.1    Chen, G.W.2    Kang, J.C.3    Chan, M.H.4
  • 66
    • 42449089893 scopus 로고    scopus 로고
    • Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation
    • DOI 10.1097/FJC.0b013e3181671439, PII 0000534420080400000008
    • Yang R, Liu A, Ma X, et al. Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation. J Cardiovasc Pharmacol 2008; 51(4): 396-401. (Pubitemid 351572239)
    • (2008) Journal of Cardiovascular Pharmacology , vol.51 , Issue.4 , pp. 396-401
    • Yang, R.1    Liu, A.2    Ma, X.3    Li, L.4    Su, D.5    Liu, J.6
  • 67
    • 34250814485 scopus 로고    scopus 로고
    • Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis
    • DOI 10.1016/j.ejphar.2007.04.031, PII S0014299907004694
    • Fu J, Huang H, Liu J, et al. Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis. Eur J Pharmacol 2007; 568(1-3): 213-221 (Pubitemid 46976900)
    • (2007) European Journal of Pharmacology , vol.568 , Issue.1-3 , pp. 213-221
    • Fu, J.1    Huang, H.2    Liu, J.3    Pi, R.4    Chen, J.5    Liu, P.6
  • 68
    • 68749120854 scopus 로고    scopus 로고
    • Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response
    • Sun Z, Huang Z, Zhang DD. Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response. PLoS One 2009; 4(8): e6588.
    • (2009) PLoS One , vol.4 , Issue.8
    • Sun, Z.1    Huang, Z.2    Zhang, D.D.3
  • 69
    • 33750430654 scopus 로고    scopus 로고
    • Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells
    • DOI 10.1002/mc.20234
    • Yuan X, Xu C, Pan Z, et al. Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells. Mol Carcinog 2006; 45(11): 841-850 (Pubitemid 44646336)
    • (2006) Molecular Carcinogenesis , vol.45 , Issue.11 , pp. 841-850
    • Yuan, X.1    Xu, C.2    Pan, Z.3    Keum, Y.-S.4    Kim, J.-H.5    Shen, G.6    Yu, S.7    Oo, K.T.8    Ma, J.9    Kong, A.-N.T.10
  • 70
    • 33947503436 scopus 로고    scopus 로고
    • Nrf2 is involved in the effect of tanshinone IIA on intracellular redox status in human aortic smooth muscle cells
    • Zhang HS, Wang SQ. Nrf2 is involved in the effect of tanshinone IIA on intracellular redox status in human aortic smooth muscle cells. Biochem Pharmacol 2007; 73(9): 1358-1366
    • (2007) Biochem Pharmacol , vol.73 , Issue.9 , pp. 1358-1366
    • Zhang, H.S.1    Wang, S.Q.2
  • 71
    • 33847684809 scopus 로고    scopus 로고
    • Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells
    • Chen TH, Hsu YT, Chen CH, Kao SH, Lee HM. Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells. Mitochondrion 2007; 7(1-2): 101-105
    • (2007) Mitochondrion , vol.7 , Issue.1-2 , pp. 101-105
    • Chen, T.H.1    Hsu, Y.T.2    Chen, C.H.3    Kao, S.H.4    Lee, H.M.5
  • 72
    • 1942532874 scopus 로고    scopus 로고
    • Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappaB and induction of apoptosis
    • DOI 10.1038/sj.onc.1207353
    • Gupta S, Hastak K, Afaq F, Ahmad N, Mukhtar H. Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis. Oncogene 2004; 23(14): 2507-2522 (Pubitemid 38520748)
    • (2004) Oncogene , vol.23 , Issue.14 , pp. 2507-2522
    • Gupta, S.1    Hastak, K.2    Afaq, F.3    Ahmad, N.4    Mukhtar, H.5
  • 73
    • 0037455718 scopus 로고    scopus 로고
    • Inhibition of ultraviolet B-mediated activation of nuclear factor κB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate
    • DOI 10.1038/sj.onc.1206206
    • Afaq F, Adhami VM, Ahmad N, Mukhtar H. Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate. Oncogene 2003; 22(7): 1035-1044 (Pubitemid 36313147)
    • (2003) Oncogene , vol.22 , Issue.7 , pp. 1035-1044
    • Afaq, F.1    Adhami, V.M.2    Ahmad, N.3    Mukhtar, H.4
  • 74
    • 1642540094 scopus 로고    scopus 로고
    • Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice
    • DOI 10.1038/sj.onc.1207035
    • Afaq F, Ahmad N, Mukhtar H. Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice. Oncogene 2003; 22(58): 9254-9264 (Pubitemid 38122037)
    • (2003) Oncogene , vol.22 , Issue.58 , pp. 9254-9264
    • Afaq, F.1    Ahmad, N.2    Mukhtar, H.3
  • 75
    • 84934442428 scopus 로고    scopus 로고
    • Cancer chemopreventive effects of curcumin
    • Surh YJ, Chun KS. Cancer chemopreventive effects of curcumin. Adv Exp Med Biol 2007; 595: 149-172
    • (2007) Adv Exp Med Biol , vol.595 , pp. 149-172
    • Surh, Y.J.1    Chun, K.S.2
  • 76
    • 0034578521 scopus 로고    scopus 로고
    • Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages
    • Pan MH, Lin-Shiau SY, Lin JK. Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. Biochem Pharmacol 2000; 60(11): 1665-1676
    • (2000) Biochem Pharmacol , vol.60 , Issue.11 , pp. 1665-1676
    • Pan, M.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 78
    • 0029047933 scopus 로고
    • Inhibition of tumor necrosis factor by curcumin, a phytochemical
    • Chan MM. Inhibition of tumor necrosis factor by curcumin, a phytochemical. Biochem Pharmacol 1995; 49(11): 1551-1556
    • (1995) Biochem Pharmacol , vol.49 , Issue.11 , pp. 1551-1556
    • Chan, M.M.1
  • 79
    • 33847077244 scopus 로고    scopus 로고
    • Curcumin prevents lipopolysaccharide-induced atrogin-1/MAFbx upregulation and muscle mass loss
    • DOI 10.1002/jcb.21060
    • Jin B, Li YP. Curcumin prevents lipopolysaccharide-induced atrogin-1/MAFbx upregulation and muscle mass loss. J Cell Biochem 2007; 100(4): 960-969 (Pubitemid 46273019)
    • (2007) Journal of Cellular Biochemistry , vol.100 , Issue.4 , pp. 960-969
    • Jin, B.1    Li, Y.-P.2
  • 80
    • 0035114277 scopus 로고    scopus 로고
    • Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production
    • Ireson C, Orr S, Jones DJ, et al. Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res 2001; 61(3): 1058-1064
    • (2001) Cancer Res , vol.61 , Issue.3 , pp. 1058-1064
    • Ireson, C.1    Orr, S.2    Jones, D.J.3
  • 81
    • 0035976049 scopus 로고    scopus 로고
    • Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells
    • DOI 10.1016/S0304-3835(01)00655-3, PII S0304383501006553
    • Goel A, Boland CR, Chauhan DP. Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett 2001; 172(2): 111-118 (Pubitemid 32889704)
    • (2001) Cancer Letters , vol.172 , Issue.2 , pp. 111-118
    • Goel, A.1    Boland, C.R.2    Chauhan, D.P.3
  • 82
    • 33745933744 scopus 로고    scopus 로고
    • 2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines
    • DOI 10.2310/7200.2005.012
    • Lev-Ari S, Maimon Y, Strier L, Kazanov D, Arber N. Down-regulation of prostaglandin E2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines. J Soc Integr Oncol 2006; 4(1): 21-26 (Pubitemid 44249829)
    • (2006) Journal of the Society for Integrative Oncology , vol.4 , Issue.1 , pp. 21-26
    • Lev-Ari, S.1    Maimon, Y.2    Strier, L.3    Kazanov, D.4    Arber, N.5
  • 83
    • 19444379739 scopus 로고    scopus 로고
    • Nrf2 as a novel molecular target for chemoprevention
    • DOI 10.1016/j.canlet.2004.09.042, PII S0304383504007360
    • Lee JS, Surh YJ. Nrf2 as a novel molecular target for chemoprevention. Cancer Lett 2005; 224(2): 171-184 (Pubitemid 40725839)
    • (2005) Cancer Letters , vol.224 , Issue.2 , pp. 171-184
    • Lee, J.-S.1    Surh, Y.-J.2
  • 84
    • 0035990608 scopus 로고    scopus 로고
    • Cellular pharmacology studies of shikonin derivatives
    • DOI 10.1002/ptr.1100
    • Chen X, Yang L, Oppenheim JJ, Howard MZ. Cellular pharmacology studies of shikonin derivatives. Phytother Res 2002; 16(3): 199-209. (Pubitemid 34534943)
    • (2002) Phytotherapy Research , vol.16 , Issue.3 , pp. 199-209
    • Chen, X.1    Yang, L.2    Oppenheim, J.J.3    Zack Howard, O.M.4
  • 85
    • 40849147137 scopus 로고    scopus 로고
    • Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-κB pathway
    • DOI 10.1002/ptr.2340
    • Min R, Tong J, Wenjun Y, et al. Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-kappaB pathway. Phytother Res 2008; 22(3): 407-415 (Pubitemid 351397447)
    • (2008) Phytotherapy Research , vol.22 , Issue.3 , pp. 407-415
    • Min, R.1    Tong, J.2    Wenjun, Y.3    Wenhu, D.4    Xiaojian, Z.5    Jiacai, H.6    Jian, Z.7    Wantao, C.8    Chenping, Z.9
  • 86
    • 56049098575 scopus 로고    scopus 로고
    • Shikonin, acetylshikonin, and isobutyroylshikonin inhibit VEGF-induced angiogenesis and suppress tumor growth in lewis lung carcinoma-bearing mice
    • Lee HJ, Magesh V, Nam D, et al. Shikonin, acetylshikonin, and isobutyroylshikonin inhibit VEGF-induced angiogenesis and suppress tumor growth in lewis lung carcinoma-bearing mice. Yakugaku Zasshi 2008; 128(11): 1681-1688
    • (2008) Yakugaku Zasshi , vol.128 , Issue.11 , pp. 1681-1688
    • Lee, H.J.1    Magesh, V.2    Nam, D.3
  • 87
    • 34247885910 scopus 로고    scopus 로고
    • DMNQ S-64 induces apoptosis via caspase activation and cyclooxygenase-2 inhibition in human nonsmall lung cancer cells
    • Lim ES, Rhee YH, Park MK, et al. DMNQ S-64 induces apoptosis via caspase activation and cyclooxygenase-2 inhibition in human nonsmall lung cancer cells. Ann NY Acad Sci 2007; 1095: 7-18.
    • (2007) Ann NY Acad Sci , vol.1095 , pp. 7-18
    • Lim, E.S.1    Rhee, Y.H.2    Park, M.K.3
  • 88
    • 52249108702 scopus 로고    scopus 로고
    • DMNQ-S17 inhibits constitutive NF-kappaB activation leading to induction of apoptosis through the activation of caspase-3 in human myeloid leukemia U937 cells
    • Park MJ, Kwon HY, Lee EO, et al. DMNQ-S17 inhibits constitutive NF-kappaB activation leading to induction of apoptosis through the activation of caspase-3 in human myeloid leukemia U937 cells. Life Sci 2008; 83(13-14): 460-467
    • (2008) Life Sci , vol.83 , Issue.13-14 , pp. 460-467
    • Park, M.J.1    Kwon, H.Y.2    Lee, E.O.3
  • 89
    • 33645542955 scopus 로고    scopus 로고
    • Antitumor effect and mechanism of shikonin derivative SYUNZ-7
    • Huang H, Xie BF, Zhu XF, et al. Antitumor effect and mechanism of shikonin derivative SYUNZ-7. Ai Zheng 2005; 24(12): 1453-1458
    • (2005) Ai Zheng , vol.24 , Issue.12 , pp. 1453-1458
    • Huang, H.1    Xie, B.F.2    Zhu, X.F.3
  • 90
    • 0242583941 scopus 로고    scopus 로고
    • Unconventional therapy for prostate cancer: Good, bad or questionable?
    • Nelson PS, Montgomery B. Unconventional therapy for prostate cancer: good, bad or questionable? Nat Rev Cancer 2003; 3(11): 845-858
    • (2003) Nat Rev Cancer , vol.3 , Issue.11 , pp. 845-858
    • Nelson, P.S.1    Montgomery, B.2
  • 91
    • 56549127848 scopus 로고    scopus 로고
    • Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cellcycle progression and inhibiting ERK, Akt, and NF-kappaB activity in vascular smooth-muscle cells
    • Peng CY, Pan SL, Huang YW, et al. Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cellcycle progression and inhibiting ERK, Akt, and NF-kappaB activity in vascular smooth-muscle cells. Naunyn Schmiedebergs Arch Pharmacol 2008; 378(6): 579-588
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.378 , Issue.6 , pp. 579-588
    • Peng, C.Y.1    Pan, S.L.2    Huang, Y.W.3
  • 92
    • 0036570319 scopus 로고    scopus 로고
    • Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells
    • Pidgeon GP, Kandouz M, Meram A, Honn KV. Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells. Cancer Res 2002; 62(9): 2721-2727 (Pubitemid 34462758)
    • (2002) Cancer Research , vol.62 , Issue.9 , pp. 2721-2727
    • Pidgeon, G.P.1    Kandouz, M.2    Meram, A.3    Honn, K.V.4
  • 93
    • 0034727789 scopus 로고    scopus 로고
    • Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin
    • Chan FL, Choi HL, Chen ZY, Chan PS, Huang Y. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Cancer Lett 2000; 160(2): 219-228
    • (2000) Cancer Lett , vol.160 , Issue.2 , pp. 219-228
    • Chan, F.L.1    Choi, H.L.2    Chen, Z.Y.3    Chan, P.S.4    Huang, Y.5
  • 94
    • 0141482095 scopus 로고    scopus 로고
    • Involvement of nuclear factor-κB in the inhibition of interleukin-12 production from mouse macrophages by baicalein, a flavonoid in Scutellaria baicalensis
    • DOI 10.1055/s-2003-42779
    • Kang BY, Chung SW, Kim SH, Cho D, Kim TS. Involvement of nuclear factor-kappaB in the inhibition of interleukin-12 production from mouse macrophages by baicalein, a flavonoid in Scutellaria baicalensis. Planta Med 2003; 69(8): 687-691 (Pubitemid 37215014)
    • (2003) Planta Medica , vol.69 , Issue.8 , pp. 687-691
    • Kang, B.Y.1    Chung, S.W.2    Kim, S.H.3    Cho, D.4    Kim, T.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.