-
1
-
-
0035126826
-
Historical perspective on the use of garlic
-
Rivlin RS. Historical perspective on the use of garlic. J Nutr. 2001;131:S951-4.
-
(2001)
J Nutr
, vol.131
-
-
Rivlin, R.S.1
-
2
-
-
0035119877
-
Intake of garlic and its bioactive components
-
Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr. 2001;131:S955-62.
-
(2001)
J Nutr
, vol.131
-
-
Amagase, H.1
Petesch, B.L.2
Matsuura, H.3
Kasuga, S.4
Itakura, Y.5
-
3
-
-
33846931878
-
Cancer chemoprevention with garlic and its constituents
-
Shukla Y, Kalra N. Cancer chemoprevention with garlic and its constituents. Cancer Lett. 2007;247:167-81.
-
(2007)
Cancer Lett
, vol.247
, pp. 167-181
-
-
Shukla, Y.1
Kalra, N.2
-
4
-
-
23844509485
-
Composition, stability, and bioavailability of garlic products used in a clinical trial
-
Lawson LD, Gardner CD. Composition, stability, and bioavailability of garlic products used in a clinical trial. J Agric Food Chem. 2005;53:6254-61.
-
(2005)
J Agric Food Chem
, vol.53
, pp. 6254-6261
-
-
Lawson, L.D.1
Gardner, C.D.2
-
5
-
-
0022039421
-
The chemistry of garlic and onions
-
Block E. The chemistry of garlic and onions. Sci Am. 1985;252:114-9.
-
(1985)
Sci Am
, vol.252
, pp. 114-119
-
-
Block, E.1
-
6
-
-
33746498322
-
Ajoene the main active compound of garlic (Allium sativum): A new antifungal agent
-
Ledezma E, Apitz-Castro R. Ajoene the main active compound of garlic (Allium sativum): a new antifungal agent. Rev Iberoam Micol. 2006;23:75-80.
-
(2006)
Rev Iberoam Micol
, vol.23
, pp. 75-80
-
-
Ledezma, E.1
Apitz-Castro, R.2
-
7
-
-
0026756541
-
The organosulfur chemistry of the genus allium. Implications for the organic chemistry of sulfur
-
Block E. The organosulfur chemistry of the genus allium. Implications for the organic chemistry of sulfur. Angew Chem Int Ed Engl. 1992;31:1135-78.
-
(1992)
Angew Chem Int Ed Engl
, vol.31
, pp. 1135-1178
-
-
Block, E.1
-
8
-
-
0026494991
-
Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation
-
Apitz-Castro R, Badimon JJ, Badimon L. Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation. Thromb Res. 1992;68:145-55.
-
(1992)
Thromb Res
, vol.68
, pp. 145-155
-
-
Apitz-Castro, R.1
Badimon, J.J.2
Badimon, L.3
-
9
-
-
0029660277
-
Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlic
-
Naganawa R, Iwata N, Ishikawa K, Fukuda H, Fujino T, Suzuki A. Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlic. Appl Environ Microbiol. 1996;62:4238-42. (Pubitemid 27262755)
-
(1996)
Applied and Environmental Microbiology
, vol.62
, Issue.11
, pp. 4238-4242
-
-
Naganawa, R.1
Iwata, N.2
Ishikawa, K.3
Fukuda, H.4
Fujino, T.5
Suzuki, A.6
-
10
-
-
33745667762
-
Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice
-
Taylor P, Noriega R, Farah C, Abad MJ, Arsenak M, Apitz R. Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Lett. 2006;239:298-304.
-
(2006)
Cancer Lett
, vol.239
, pp. 298-304
-
-
Taylor, P.1
Noriega, R.2
Farah, C.3
Abad, M.J.4
Arsenak, M.5
Apitz, R.6
-
11
-
-
0033230043
-
Glutathione and its role in cellular functions
-
Sies H. Glutathione and its role in cellular functions. Free Radic Biol Med. 1999;27:916-21.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 916-921
-
-
Sies, H.1
-
12
-
-
0037653659
-
Gender difference in glutathione metabolism during aging in mice
-
Wang H, Liu H, Liu RM. Gender difference in glutathione metabolism during aging in mice. Exp Gerontol. 2003;38:507-17.
-
(2003)
Exp Gerontol
, vol.38
, pp. 507-517
-
-
Wang, H.1
Liu, H.2
Liu, R.M.3
-
13
-
-
0028797103
-
Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: Regulation of glutathione synthesis and efflux
-
Yoshida K, Hirokawa J, Tagami S, Kawakami Y, Urata Y, Kondo T. Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia. 1995;38:201-10.
-
(1995)
Diabetologia
, vol.38
, pp. 201-210
-
-
Yoshida, K.1
Hirokawa, J.2
Tagami, S.3
Kawakami, Y.4
Urata, Y.5
Kondo, T.6
-
14
-
-
0034980722
-
Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: Association with glutathione levels and drug resistance in the National Cancer Institute tumor cell line panel
-
Walsh AC, Feulner JA, Reilly A. Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: association with glutathione levels and drug resistance in the National Cancer Institute tumor cell line panel. Toxicol Sci. 2001;61:218-23.
-
(2001)
Toxicol Sci
, vol.61
, pp. 218-223
-
-
Walsh, A.C.1
Feulner, J.A.2
Reilly, A.3
-
15
-
-
0026749890
-
Enhanced sinusoidal glutathione efflux during endotoxin-induced oxidant stress in vivo
-
Jaeschke H. Enhanced sinusoidal glutathione efflux during endotoxin-induced oxidant stress in vivo. Am J Physiol. 1992;263:G60-8.
-
(1992)
Am J Physiol
, vol.263
-
-
Jaeschke, H.1
-
16
-
-
0036709597
-
Cellular glutathione and thiols metabolism
-
Dickinson DA, Forman HJ. Cellular glutathione and thiols metabolism. Biochem Pharmacol. 2002;64:1019-26.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1019-1026
-
-
Dickinson, D.A.1
Forman, H.J.2
-
17
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999;13:76-86. (Pubitemid 29045117)
-
(1999)
Genes and Development
, vol.13
, Issue.1
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
18
-
-
0029411321
-
Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: Regulation by upstream antioxidant-responsive elements (ARE)
-
Prestera T, Talalay P, Alam J, Ahn YI, Lee PJ, Choi AM. Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). Mol Med. 1995;1:827-37. (Pubitemid 3013090)
-
(1995)
Molecular Medicine
, vol.1
, Issue.7
, pp. 827-837
-
-
Prestera, T.1
Talalay, P.2
Alam, J.3
Ahn, Y.I.4
Lee, P.J.5
Choi, A.M.6
-
19
-
-
0037763721
-
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
-
Nguyen T, Sherratt PJ, Pickett CB. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu Rev Pharmacol Toxicol. 2003;43:233-60.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 233-260
-
-
Nguyen, T.1
Sherratt, P.J.2
Pickett, C.B.3
-
20
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto A, Itoh K, Nagayoshi E, Haruta J, Kimura T. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci. 2001;59:169-77.
-
(2001)
Toxicol Sci
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
-
21
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in Nrf2 transcription factor-deficient mice
-
Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in Nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA. 2001;98:3410-5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
-
22
-
-
0036884409
-
Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation
-
Kang KW, Kim YG, Cho MK, Bae SK, Kim CW, Lee MG, Kim SG. Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation. FASEB J. 2002;16:1988-90.
-
(2002)
FASEB J
, vol.16
, pp. 1988-1990
-
-
Kang, K.W.1
Kim, Y.G.2
Cho, M.K.3
Bae, S.K.4
Kim, C.W.5
Lee, M.G.6
Kim, S.G.7
-
23
-
-
18144417838
-
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: Role of SMRT recruited to GR in GSTA2 gene repression
-
Ki SH, Cho IJ, Choi DW, Kim SG. Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression. Mol Cell Biol. 2005;25:4150-65.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4150-4165
-
-
Ki, S.H.1
Cho, I.J.2
Choi, D.W.3
Kim, S.G.4
-
24
-
-
34548757301
-
Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway
-
Bae EJ, Yang YM, Kim JW, Kim SG. Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway. Hepatology. 2007;46:730-9.
-
(2007)
Hepatology
, vol.46
, pp. 730-739
-
-
Bae, E.J.1
Yang, Y.M.2
Kim, J.W.3
Kim, S.G.4
-
25
-
-
0032104212
-
Overlapping antioxidant response element and PMA response element sequences mediate basal and β-naphthoflavone-induced expression of the human γ-glutamylcysteine synthetase catalytic subunit gene
-
Wild AC, Gipp JJ, Mulcahy RT. Overlapping antioxidant response element and PMA response element sequences mediate basal and β-naphthoflavone- induced expression of the human γ-glutamylcysteine synthetase catalytic subunit gene. Biochem J. 1998;332:373-81.
-
(1998)
Biochem J
, vol.332
, pp. 373-381
-
-
Wild, A.C.1
Gipp, J.J.2
Mulcahy, R.T.3
-
26
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, O'Connor T, Yamamoto M. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells. 2003;8:379-91.
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
O'Connor, T.5
Yamamoto, M.6
-
27
-
-
0242666198
-
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
-
Bloom DA, Jaiswal AK. Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. J Biol Chem. 2003;278:44675-82.
-
(2003)
J Biol Chem
, vol.278
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
28
-
-
41549108838
-
Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells
-
Kode A, Rajendrasozhan S, Caito S, Yang SR, Megson IL, Rahman I. Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2008;294:L478-88.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Kode, A.1
Rajendrasozhan, S.2
Caito, S.3
Yang, S.R.4
Megson, I.L.5
Rahman, I.6
-
29
-
-
69249240216
-
Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury
-
Kim YW, Lee SM, Shin SM, Hwang SJ, Brooks JS, Kang HE, Lee MG, Kim SC, Kim SG. Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. Free Radic Biol Med. 2009;47:1082-92.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 1082-1092
-
-
Kim, Y.W.1
Lee, S.M.2
Shin, S.M.3
Hwang, S.J.4
Brooks, J.S.5
Kang, H.E.6
Lee, M.G.7
Kim, S.C.8
Kim, S.G.9
-
30
-
-
70349324339
-
Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose) polymerase-LKB1 pathway
-
Shin SM, Cho IJ, Kim SG. Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose) polymerase-LKB1 pathway. Mol Pharmacol. 2009;76:884-95.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 884-895
-
-
Shin, S.M.1
Cho, I.J.2
Kim, S.G.3
-
31
-
-
58849093275
-
Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners
-
Shin SM, Kim SG. Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners. Mol Pharmacol. 2009;75:242-53.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 242-253
-
-
Shin, S.M.1
Kim, S.G.2
-
32
-
-
0028334763
-
Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells
-
Gebhardt R, Beck H, Wagner KG. Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells. Biochim Biophys Acta. 1994;1213:57-62.
-
(1994)
Biochim Biophys Acta
, vol.1213
, pp. 57-62
-
-
Gebhardt, R.1
Beck, H.2
Wagner, K.G.3
-
33
-
-
34247871313
-
Enhancement of ajoene-induced apoptosis by conjugated linoleic acid in 3T3-L1 adipocytes
-
Yang JY, Della-Fera MA, Hausman DB, Baile CA. Enhancement of ajoene-induced apoptosis by conjugated linoleic acid in 3T3-L1 adipocytes. Apoptosis. 2007;12:1117-28.
-
(2007)
Apoptosis
, vol.12
, pp. 1117-1128
-
-
Yang, J.Y.1
Della-Fera, M.A.2
Hausman, D.B.3
Baile, C.A.4
-
34
-
-
0025006711
-
The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines
-
Scharfenberg K, Wagner R, Wagner KG. The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines. Cancer Lett. 1990;53:103-8. (Pubitemid 20323600)
-
(1990)
Cancer Letters
, vol.53
, Issue.2-3
, pp. 103-108
-
-
Scharfenberg, K.1
Wagner, R.2
Wagner, K.G.3
-
35
-
-
1242274394
-
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes
-
Kang MI, Kobayashi A, Wakabayashi N, Kim SG, Yamamoto M. Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes. Proc Natl Acad Sci USA. 2004;101:2046-51.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2046-2051
-
-
Kang, M.I.1
Kobayashi, A.2
Wakabayashi, N.3
Kim, S.G.4
Yamamoto, M.5
-
36
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon M, Itoh K, Yamamoto M, Hayes JD. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J Biol Chem. 2003;278:21592-600.
-
(2003)
J Biol Chem
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
37
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang DD, Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol. 2003;23:8137-51.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
38
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 2002;62:5196-203.
-
(2002)
Cancer Res
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
39
-
-
0033546686
-
Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element
-
Moinova HR, Mulcahy RT. Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element. Biochem Biophys Res Commun. 1999;261:661-8.
-
(1999)
Biochem Biophys Res Commun
, vol.261
, pp. 661-668
-
-
Moinova, H.R.1
Mulcahy, R.T.2
-
40
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
-
Wakabayashi N, Dinkova-Kostova AT, Holtzclaw WD, Kang MI, Kobayashi A. Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers. Proc Natl Acad Sci USA. 2004;101:2040-5.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.I.4
Kobayashi, A.5
-
41
-
-
4344688670
-
Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals
-
Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, et al. Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. J Immunol. 2004;173:3467-81.
-
(2004)
J Immunol
, vol.173
, pp. 3467-3481
-
-
Li, N.1
Alam, J.2
Venkatesan, M.I.3
Eiguren-Fernandez, A.4
Schmitz, D.5
Di Stefano, E.6
Slaughter, N.7
Killeen, E.8
Wang, X.9
-
42
-
-
0030956247
-
Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence
-
Mulcahy RT, Wartman MA, Bailey HH, Gipp JJ. Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence. J Biol Chem. 1997;272:7445-54.
-
(1997)
J Biol Chem
, vol.272
, pp. 7445-7454
-
-
Mulcahy, R.T.1
Wartman, M.A.2
Bailey, H.H.3
Gipp, J.J.4
-
43
-
-
27444447043
-
Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1
-
Yang H, Magilnick N, Ou X, Lu SC. Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1. Biochem J. 2005;391:399-408.
-
(2005)
Biochem J
, vol.391
, pp. 399-408
-
-
Yang, H.1
Magilnick, N.2
Ou, X.3
Lu, S.C.4
-
44
-
-
0031976715
-
Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB
-
Dirsch VM, Gerbes AL, Vollmar AM. Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB. Mol Pharmacol. 1998;53:402-7.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 402-407
-
-
Dirsch, V.M.1
Gerbes, A.L.2
Vollmar, A.M.3
-
45
-
-
0034687543
-
Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes
-
Zipper LM, Mulcahy RT. Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes. Biochem Biophys Res Commun. 2000;278:484-92.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 484-492
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
46
-
-
0037044791
-
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
-
Huang HC, Nguyen T, Pickett CB. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J Biol Chem. 2002;277:42769-74.
-
(2002)
J Biol Chem
, vol.277
, pp. 42769-42774
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, C.B.3
-
47
-
-
0028339457
-
Rottlerin, a novel protein kinase inhibitor
-
DOI 10.1006/bbrc.1994.1199
-
Gschwendt M, Müller HJ, Kielbassa K, Zang R, Kittstein W, Rincke G, Marks F. Rottlerin, a novel protein kinase inhibitor. Biochem Biophys Res Commun. 1994;199:93-8. (Pubitemid 24179919)
-
(1994)
Biochemical and Biophysical Research Communications
, vol.199
, Issue.1
, pp. 93-98
-
-
Gschwendt, M.1
Muller, H.J.2
Kielbassa, K.3
Zang, R.4
Kittstein, W.5
Rincke, G.6
Marks, F.7
-
48
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 2000;351:95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
49
-
-
67650475217
-
The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta connecting neurotransmission with neuroprotection
-
Espada S, Rojo AI, Salinas M, Cuadrado A. The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection. J Neurochem. 2009;110:1107-19.
-
(2009)
J Neurochem
, vol.110
, pp. 1107-1119
-
-
Espada, S.1
Rojo, A.I.2
Salinas, M.3
Cuadrado, A.4
-
50
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman ER. Protein oxidation and aging. Science. 1992;257:1220-4.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
51
-
-
0033609069
-
Mitochondrial disease in mouse results in increased oxidative stress
-
Esposito LA, Melov S, Panov A, Cottrell BA, Wallace DC. Mitochondrial disease in mouse results in increased oxidative stress. Proc Natl Acad Sci USA. 1999;96:4820-5.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4820-4825
-
-
Esposito, L.A.1
Melov, S.2
Panov, A.3
Cottrell, B.A.4
Wallace, D.C.5
-
52
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
Cadenas E, Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med. 2000;29:222-30.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
53
-
-
0026542675
-
Inhibition of the activity of glutathione peroxidase by tertiary-butylhydroperoxide in cultured Chinese hamster cells and the role of cellular glutathione in the recovery of the activity
-
Ochi T. Inhibition of the activity of glutathione peroxidase by tertiary-butylhydroperoxide in cultured Chinese hamster cells and the role of cellular glutathione in the recovery of the activity. Toxicology. 1992;71:119-27.
-
(1992)
Toxicology
, vol.71
, pp. 119-127
-
-
Ochi, T.1
-
54
-
-
0033795435
-
Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alpha-tocopherol and glutathione
-
Chen HW, Chiang T, Wang CY, Lii CK. Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alpha-tocopherol and glutathione. Food Chem Toxicol. 2000;38:1089-96.
-
(2000)
Food Chem Toxicol
, vol.38
, pp. 1089-1096
-
-
Chen, H.W.1
Chiang, T.2
Wang, C.Y.3
Lii, C.K.4
-
55
-
-
28144445947
-
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity
-
Okawa H, Motohashi H, Kobayashi A, Aburatani H, Kensler TW, Yamamoto M. Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. Biochem Biophys Res Commun. 2006;339:79-88.
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 79-88
-
-
Okawa, H.1
Motohashi, H.2
Kobayashi, A.3
Aburatani, H.4
Kensler, T.W.5
Yamamoto, M.6
-
56
-
-
0026578442
-
Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products
-
Lawson LD, Ransom DK, Hughes BG. Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products. Thromb Res. 1992;65:141-56.
-
(1992)
Thromb Res
, vol.65
, pp. 141-156
-
-
Lawson, L.D.1
Ransom, D.K.2
Hughes, B.G.3
|