Dihydroquercetin (DHQ) induced HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 11, 2013, Pages 2755-2761

  Liang, Lu ^a   Gao, Chang ^b   Luo, Meng ^a   Wang, Wei ^a   Zhao, Chunjian ^a   Zu, Yuangang ^a   Efferth, Thomas ^c   Fu, Yujie ^a  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

antioxidant activity; antioxidant genes; dihydroquercetin; Nrf2

Indexed keywords

ANTI-OXIDANT ACTIVITIES; ANTIOXIDANT RESPONSE ELEMENTS; DIHYDROQUERCETIN; GLUTAMATE-CYSTEINE LIGASE; LUCIFERASE REPORTER ASSAYS; NRF2; NUCLEAR TRANSLOCATIONS; TRANSCRIPTIONAL ACTIVITY;

AMINO ACIDS; GENES; PIGMENTS;

PLANTS (BOTANY);

ANTIOXIDANT; DRUG DERIVATIVE; HEME OXYGENASE 1; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; PLANT EXTRACT; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TAXIFOLIN; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CHEMISTRY; DRUG EFFECT; GENETICS; HEPG2 CELL LINE; HUMAN; LARIX; METABOLISM; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION;

ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; LARIX; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PLANT EXTRACTS; QUERCETIN; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84875477327     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf304768p     Document Type: Article

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