Arresting initiation of hepatitis C virus RNA synthesis using heterocyclic derivatives

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 16602-16607

  Gu, Baohua ^a   Johnston, Victor K ^a   Gutshall, Lester L ^a   Nguyen, Tammy T ^a   Gontarek, Richard R ^a   Darcy, Michael G ^a   Tedesco, Rosanna ^a   Dhanak, Dashyant ^a   Duffy, Kevin J ^a   Kao, C Cheng ^b   Sarisky, Robert T ^a,c  

^a GLAXOSMITHKLINE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c CENTOCOR INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYST ACTIVITY; ENZYME INHIBITION; GENETIC ENGINEERING; RNA; SURFACE PLASMON RESONANCE; VIRUSES;

PROTEIN ENCODING;

BIOCHEMICAL ENGINEERING;

BENZOTHIADIAZINE DERIVATIVE; HEPARIN; HETEROCYCLIC COMPOUND; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN NS5B; VIRUS RNA; ENZYME INHIBITOR; RNA DIRECTED RNA POLYMERASE; THIADIAZINE DERIVATIVE;

ARTICLE; CHRONIC HEPATITIS; HEPATITIS C; HEPATITIS C VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; RNA SYNTHESIS; RNA VIRUS; SURFACE PLASMON RESONANCE; VIRUS HEPATITIS; VIRUS INHIBITION; VIRUS REPLICATION; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; PHYSIOLOGY;

HEPATITIS C VIRUS; RNA VIRUSES;

ENZYME INHIBITORS; HEPACIVIRUS; RNA REPLICASE; RNA, VIRAL; THIADIAZINES; VIRUS REPLICATION;

EID: 0038269108     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210891200     Document Type: Article

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