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Volumn 4, Issue 2, 2014, Pages 95-111

Drug repurposing and human parasitic protozoan diseases

Author keywords

Antiparasitic; Cryptosporidium; Drug repurposing; Leishmaniasis; Malaria; Toxoplasmosis; Trypanosomiasis

Indexed keywords

AMPHOTERICIN B CHOLESTEROL SULFATE; AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; ANTIPROTOZOAL AGENT; ARTEMETHER; ARTEMISININ; ATOVAQUONE; AZITHROMYCIN; CHLOROQUINE; CHLORPROGUANIL; CLINDAMYCIN; COTRIMOXAZOLE; DAPSONE; DOXYCYCLINE; EFLORNITHINE; MELARSOPROL; MILTEFOSINE; NIFURTIMOX; NITAZOXANIDE; PAROMOMYCIN; PENTAMIDINE; PRAZIQUANTEL; PROGUANIL; PYRIMETHAMINE; QUININE; SPIRAMYCIN; SULFADIAZINE; SULFADOXINE; SULFONAMIDE; SURAMIN;

EID: 84897973164     PISSN: 22113207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpddr.2014.02.002     Document Type: Review
Times cited : (315)

References (224)
  • 1
    • 70350031257 scopus 로고    scopus 로고
    • Dispersible formulation of artemether/lumefantrine: specifically developed for infants and young children
    • Abdulla S., Sagara I. Dispersible formulation of artemether/lumefantrine: specifically developed for infants and young children. Malar. J. 2009, 8(Suppl. 1):S7.
    • (2009) Malar. J. , vol.8 , Issue.SUPPL. 1
    • Abdulla, S.1    Sagara, I.2
  • 3
    • 0022499206 scopus 로고
    • Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer
    • Abeloff M.D., Rosen S.T., Luk G.D., Baylin S.B., Zeltzman M., Sjoerdsma A. Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer. Cancer Treat. Rep. 1986, 70(7):843-845.
    • (1986) Cancer Treat. Rep. , vol.70 , Issue.7 , pp. 843-845
    • Abeloff, M.D.1    Rosen, S.T.2    Luk, G.D.3    Baylin, S.B.4    Zeltzman, M.5    Sjoerdsma, A.6
  • 7
    • 73149102077 scopus 로고    scopus 로고
    • High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial
    • Amadi B., Mwiya M., Sianongo S., Payne L., Watuka A., Katubulushi M., Kelly P. High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial. BMC Infect. Dis. 2009, 9:195.
    • (2009) BMC Infect. Dis. , vol.9 , pp. 195
    • Amadi, B.1    Mwiya, M.2    Sianongo, S.3    Payne, L.4    Watuka, A.5    Katubulushi, M.6    Kelly, P.7
  • 10
    • 84867532069 scopus 로고    scopus 로고
    • Towards histone deacetylase inhibitors as new antimalarial drugs
    • Andrews K.T., Tran T.N., Fairlie D.P. Towards histone deacetylase inhibitors as new antimalarial drugs. Curr. Pharm. Des. 2012, 18(24):3467-3479.
    • (2012) Curr. Pharm. Des. , vol.18 , Issue.24 , pp. 3467-3479
    • Andrews, K.T.1    Tran, T.N.2    Fairlie, D.P.3
  • 12
    • 84865832714 scopus 로고    scopus 로고
    • The global pipeline of new medicines for the control and elimination of malaria
    • Anthony M.P., Burrows J.N., Duparc S., Moehrle J.J., Wells T.N. The global pipeline of new medicines for the control and elimination of malaria. Malar. J. 2012, 11:316.
    • (2012) Malar. J. , vol.11 , pp. 316
    • Anthony, M.P.1    Burrows, J.N.2    Duparc, S.3    Moehrle, J.J.4    Wells, T.N.5
  • 13
    • 0026073466 scopus 로고
    • Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii
    • Araujo F.G., Huskinson J., Remington J.S. Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii. Antimicrob. Agents Chemother. 1991, 35(2):293-299.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , Issue.2 , pp. 293-299
    • Araujo, F.G.1    Huskinson, J.2    Remington, J.S.3
  • 15
    • 4344668661 scopus 로고    scopus 로고
    • Drug repositioning: identifying and developing new uses for existing drugs
    • Ashburn T.T., Thor K.B. Drug repositioning: identifying and developing new uses for existing drugs. Nat Rev Drug Disc. 2004, 3(8):673-683.
    • (2004) Nat Rev Drug Disc. , vol.3 , Issue.8 , pp. 673-683
    • Ashburn, T.T.1    Thor, K.B.2
  • 17
    • 84874237745 scopus 로고    scopus 로고
    • Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story
    • Baker N., de Koning H.P., Maser P., Horn D. Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story. Trends Parasitol. 2013, 29(3):110-118.
    • (2013) Trends Parasitol. , vol.29 , Issue.3 , pp. 110-118
    • Baker, N.1    de Koning, H.P.2    Maser, P.3    Horn, D.4
  • 18
    • 0032795221 scopus 로고    scopus 로고
    • Randomized trial of prolonged chloroquine therapy in advanced pulmonary sarcoidosis
    • Baltzan M., Mehta S., Kirkham T.H., Cosio M.G. Randomized trial of prolonged chloroquine therapy in advanced pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 1999, 160(1):192-197.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , Issue.1 , pp. 192-197
    • Baltzan, M.1    Mehta, S.2    Kirkham, T.H.3    Cosio, M.G.4
  • 21
    • 36949016420 scopus 로고    scopus 로고
    • Cinchonism in a patient taking Quinine for leg cramps
    • Barrocas A.M., Cymet T. Cinchonism in a patient taking Quinine for leg cramps. Compr. Ther. 2007, 33(3):162-163.
    • (2007) Compr. Ther. , vol.33 , Issue.3 , pp. 162-163
    • Barrocas, A.M.1    Cymet, T.2
  • 23
    • 84867513471 scopus 로고    scopus 로고
    • Protein kinases as potential targets for novel anti-schistosomal strategies
    • Beckmann S., Leutner S., Gouignard N., Dissous C., Grevelding C.G. Protein kinases as potential targets for novel anti-schistosomal strategies. Curr. Pharm. Des. 2012, 18(24):3579-3594.
    • (2012) Curr. Pharm. Des. , vol.18 , Issue.24 , pp. 3579-3594
    • Beckmann, S.1    Leutner, S.2    Gouignard, N.3    Dissous, C.4    Grevelding, C.G.5
  • 27
    • 52649153653 scopus 로고    scopus 로고
    • Treatment of leishmaniasis with miltefosine: 2008 status
    • Berman J.J. Treatment of leishmaniasis with miltefosine: 2008 status. Expert Opin. Drug Metab. Toxicol. 2008, 4(9):1209-1216.
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , Issue.9 , pp. 1209-1216
    • Berman, J.J.1
  • 29
    • 34548702901 scopus 로고    scopus 로고
    • Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance
    • Bernhard S.C., Nerima B., Maser P., Brun R. Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance. Int. J. Parasitol. 2007, 37(13):1443-1448.
    • (2007) Int. J. Parasitol. , vol.37 , Issue.13 , pp. 1443-1448
    • Bernhard, S.C.1    Nerima, B.2    Maser, P.3    Brun, R.4
  • 30
    • 84875197025 scopus 로고    scopus 로고
    • Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth
    • Bessoff K., Sateriale A., Lee K.K., Huston C.D. Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth. Antimicrob. Agents Chemother. 2013, 57(4):1804-1814.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , Issue.4 , pp. 1804-1814
    • Bessoff, K.1    Sateriale, A.2    Lee, K.K.3    Huston, C.D.4
  • 31
    • 0029061493 scopus 로고
    • Lupus anticoagulant in the elderly may be associated with both quinine and quinidine usage
    • Bird M.R., O'Neill A.I., Buchanan R.R., Ibrahim K.M., Des Parkin J. Lupus anticoagulant in the elderly may be associated with both quinine and quinidine usage. Pathology 1995, 27(2):136-139.
    • (1995) Pathology , vol.27 , Issue.2 , pp. 136-139
    • Bird, M.R.1    O'Neill, A.I.2    Buchanan, R.R.3    Ibrahim, K.M.4    Des Parkin, J.5
  • 33
    • 54949108677 scopus 로고    scopus 로고
    • PubChem: integrated platform of small molecules and biological activities
    • (Chapter 12)
    • Bolton E., Wang Y., Thiessen P.A., Bryant S.H. PubChem: integrated platform of small molecules and biological activities. Annu. Rep. Comput. Chem. 2008, 4. (Chapter 12).
    • (2008) Annu. Rep. Comput. Chem. , vol.4
    • Bolton, E.1    Wang, Y.2    Thiessen, P.A.3    Bryant, S.H.4
  • 34
    • 84967961893 scopus 로고
    • British Medical Journal Sulphadiazine
    • British Medical Journal Sulphadiazine. Br. Med. J. 1942, 1(4228):76-77.
    • (1942) Br. Med. J. , vol.1 , Issue.4228 , pp. 76-77
  • 35
    • 84897997986 scopus 로고
    • TOXOPLASMIC uveitis and pyrimethamine (author not listed)
    • British Medical Journal
    • British Medical Journal TOXOPLASMIC uveitis and pyrimethamine (author not listed). Br. Med. J. 1957, 2(5052):1042-1044.
    • (1957) Br. Med. J. , vol.2 , Issue.5052 , pp. 1042-1044
  • 36
    • 49049097255 scopus 로고    scopus 로고
    • Development and in vitro evaluation of chloroquine gels as microbicides against HIV-1 infection
    • Brouwers J., Vermeire K., Schols D., Augustijns P. Development and in vitro evaluation of chloroquine gels as microbicides against HIV-1 infection. Virology 2008, 378(2):306-310.
    • (2008) Virology , vol.378 , Issue.2 , pp. 306-310
    • Brouwers, J.1    Vermeire, K.2    Schols, D.3    Augustijns, P.4
  • 37
    • 0034777039 scopus 로고    scopus 로고
    • The phenomenon of treatment failures in Human African Trypanosomiasis
    • Brun R., Schumacher R., Schmid C., Kunz C., Burri C. The phenomenon of treatment failures in Human African Trypanosomiasis. Trop. Med. Int. Health 2001, 6(11):906-914.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.11 , pp. 906-914
    • Brun, R.1    Schumacher, R.2    Schmid, C.3    Kunz, C.4    Burri, C.5
  • 38
    • 79959790904 scopus 로고    scopus 로고
    • Development of novel drugs for human African trypanosomiasis
    • Brun R., Don R., Jacobs R.T., Wang M.Z., Barrett M.P. Development of novel drugs for human African trypanosomiasis. Future Microbiol. 2011, 6(6):677-691.
    • (2011) Future Microbiol. , vol.6 , Issue.6 , pp. 677-691
    • Brun, R.1    Don, R.2    Jacobs, R.T.3    Wang, M.Z.4    Barrett, M.P.5
  • 39
    • 0038639784 scopus 로고    scopus 로고
    • Eflornithine for the treatment of human African trypanosomiasis
    • Burri C., Brun R. Eflornithine for the treatment of human African trypanosomiasis. Parasitol. Res. 2003, 90(Supp 1):S49-S52.
    • (2003) Parasitol. Res. , vol.90 , Issue.SUPPL. 1
    • Burri, C.1    Brun, R.2
  • 40
    • 0034991804 scopus 로고    scopus 로고
    • Pharmacokinetic investigations in patients from northern Angola refractory to melarsoprol treatment
    • Burri C., Keiser J. Pharmacokinetic investigations in patients from northern Angola refractory to melarsoprol treatment. Trop. Med. Int. Health 2001, 6(5):412-420.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.5 , pp. 412-420
    • Burri, C.1    Keiser, J.2
  • 43
    • 68549101792 scopus 로고    scopus 로고
    • Recent advances in the development of polyamine analogues as antitumor agents
    • Casero R.A., Woster P.M. Recent advances in the development of polyamine analogues as antitumor agents. J. Med. Chem. 2009, 52(15):4551-4573.
    • (2009) J. Med. Chem. , vol.52 , Issue.15 , pp. 4551-4573
    • Casero, R.A.1    Woster, P.M.2
  • 44
    • 79952967329 scopus 로고    scopus 로고
    • Drug discovery and development for neglected diseases: the DNDi model
    • Chatelain E., Ioset J.R. Drug discovery and development for neglected diseases: the DNDi model. Drug Des. Dev. Ther. 2011, 5:175-181.
    • (2011) Drug Des. Dev. Ther. , vol.5 , pp. 175-181
    • Chatelain, E.1    Ioset, J.R.2
  • 47
    • 33746381549 scopus 로고    scopus 로고
    • A clinical drug library screen identifies astemizole as an antimalarial agent
    • Chong C.R., Chen X., Shi L., Liu J.O., Sullivan D.J. A clinical drug library screen identifies astemizole as an antimalarial agent. Nat. Chem. Biol. 2006, 2(8):415-416.
    • (2006) Nat. Chem. Biol. , vol.2 , Issue.8 , pp. 415-416
    • Chong, C.R.1    Chen, X.2    Shi, L.3    Liu, J.O.4    Sullivan, D.J.5
  • 48
    • 0016755327 scopus 로고
    • Clindamycin vs placebo as adjunctive therapy in moderately severe acne
    • Christian G.L., Krueger G.G. Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Arch. Dermatol. 1975, 111(8):997-1000.
    • (1975) Arch. Dermatol. , vol.111 , Issue.8 , pp. 997-1000
    • Christian, G.L.1    Krueger, G.G.2
  • 50
    • 0016812414 scopus 로고
    • Comparison of metronidazole and chloroquine for the treatment of amoebic liver abscess
    • Cohen H.G., Reynolds T.B. Comparison of metronidazole and chloroquine for the treatment of amoebic liver abscess. Control. Trial Gastroenterol. 1975, 69(1):35-41.
    • (1975) Control. Trial Gastroenterol. , vol.69 , Issue.1 , pp. 35-41
    • Cohen, H.G.1    Reynolds, T.B.2
  • 51
    • 85015295681 scopus 로고
    • The local treatment of burns with sulfadiazine spray
    • Coloviras G.J., West W.T., Armour J.C. The local treatment of burns with sulfadiazine spray. Can. Med. Assoc. J. 1942, 47(6):505-514.
    • (1942) Can. Med. Assoc. J. , vol.47 , Issue.6 , pp. 505-514
    • Coloviras, G.J.1    West, W.T.2    Armour, J.C.3
  • 52
    • 0034661807 scopus 로고    scopus 로고
    • Sources of toxoplasma infection in pregnant women: European multicentre case-control study. European research network on congenital toxoplasmosis
    • Cook A.J., Gilbert R.E., Buffolano W., Zufferey J., Petersen E., Jenum P.A., Foulon W., Semprini A.E., Dunn D.T. Sources of toxoplasma infection in pregnant women: European multicentre case-control study. European research network on congenital toxoplasmosis. BMJ 2000, 321(7254):142-147.
    • (2000) BMJ , vol.321 , Issue.7254 , pp. 142-147
    • Cook, A.J.1    Gilbert, R.E.2    Buffolano, W.3    Zufferey, J.4    Petersen, E.5    Jenum, P.A.6    Foulon, W.7    Semprini, A.E.8    Dunn, D.T.9
  • 53
    • 77954187759 scopus 로고    scopus 로고
    • Chagas disease: a new worldwide challenge
    • Coura J.R., Vinas P.A. Chagas disease: a new worldwide challenge. Nature 2010, 465(7301):S6-S7.
    • (2010) Nature , vol.465 , Issue.7301
    • Coura, J.R.1    Vinas, P.A.2
  • 54
    • 0030961481 scopus 로고    scopus 로고
    • Comparative controlled study on the use of benznidazole, nifurtimox and placebo, in the chronic form of Chagas' disease, in a field area with interrupted transmission. I. Preliminary evaluation
    • Coura J.R., de Abreu L.L., Willcox H.P., Petana W. Comparative controlled study on the use of benznidazole, nifurtimox and placebo, in the chronic form of Chagas' disease, in a field area with interrupted transmission. I. Preliminary evaluation. Rev. Soc. Bras. Med. Trop. 1997, 30(2):139-144.
    • (1997) Rev. Soc. Bras. Med. Trop. , vol.30 , Issue.2 , pp. 139-144
    • Coura, J.R.1    de Abreu, L.L.2    Willcox, H.P.3    Petana, W.4
  • 55
    • 0023809380 scopus 로고
    • Prophylaxis of congenital toxoplasmosis. Effects of spiramycin on placental infection
    • Couvreur J., Desmonts G., Thulliez P. Prophylaxis of congenital toxoplasmosis. Effects of spiramycin on placental infection. J. Antimicrob. Chemother. 1988, 22(Suppl. B):193-200.
    • (1988) J. Antimicrob. Chemother. , vol.22 , Issue.SUPPL. B , pp. 193-200
    • Couvreur, J.1    Desmonts, G.2    Thulliez, P.3
  • 56
    • 0142258171 scopus 로고    scopus 로고
    • Leishmaniasis - current chemotherapy and recent advances in the search for novel drugs
    • Croft S.L., Coombs G.H. Leishmaniasis - current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol. 2003, 19(11):502-508.
    • (2003) Trends Parasitol. , vol.19 , Issue.11 , pp. 502-508
    • Croft, S.L.1    Coombs, G.H.2
  • 57
    • 0037325060 scopus 로고    scopus 로고
    • Antiprotozoal activities of phospholipid analogues
    • Croft S.L., Seifert K., Duchene M. Antiprotozoal activities of phospholipid analogues. Mol. Biochem. Parasitol. 2003, 126(2):165-172.
    • (2003) Mol. Biochem. Parasitol. , vol.126 , Issue.2 , pp. 165-172
    • Croft, S.L.1    Seifert, K.2    Duchene, M.3
  • 59
    • 0026515452 scopus 로고
    • Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group
    • Dannemann B., McCutchan J.A., Israelski D., Antoniskis D., Leport C., Luft B., Nussbaum J., Clumeck N., Morlat P., Chiu J., et al. Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group. Ann. Intern. Med. 1992, 116(1):33-43.
    • (1992) Ann. Intern. Med. , vol.116 , Issue.1 , pp. 33-43
    • Dannemann, B.1    McCutchan, J.A.2    Israelski, D.3    Antoniskis, D.4    Leport, C.5    Luft, B.6    Nussbaum, J.7    Clumeck, N.8    Morlat, P.9    Chiu, J.10
  • 63
    • 84861904136 scopus 로고    scopus 로고
    • Liver-stage malaria parasites vulnerable to diverse chemical scaffolds
    • Derbyshire E.R., Prudencio M., Mota M.M., Clardy J. Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proc. Natl. Acad. Sci. USA 2012, 109(22):8511-8516.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , Issue.22 , pp. 8511-8516
    • Derbyshire, E.R.1    Prudencio, M.2    Mota, M.M.3    Clardy, J.4
  • 65
    • 0016394869 scopus 로고
    • Congenital toxoplasmosis. A prospective study of 378 pregnancies
    • Desmonts G., Couvreur J. Congenital toxoplasmosis. A prospective study of 378 pregnancies. N. Engl. J. Med. 1974, 290(20):1110-1116.
    • (1974) N. Engl. J. Med. , vol.290 , Issue.20 , pp. 1110-1116
    • Desmonts, G.1    Couvreur, J.2
  • 66
    • 0015962176 scopus 로고
    • Toxoplasmosis in pregnancy and its transmission to the fetus
    • Desmonts G., Couvreur J. Toxoplasmosis in pregnancy and its transmission to the fetus. Bull. N.Y. Acad. Med. 1974, 50(2):146-159.
    • (1974) Bull. N.Y. Acad. Med. , vol.50 , Issue.2 , pp. 146-159
    • Desmonts, G.1    Couvreur, J.2
  • 67
    • 84884248924 scopus 로고    scopus 로고
    • Research perspective: potential role of nitazoxanide in ovarian cancer treatment. Old drug, new purpose?
    • Di Santo N., Ehrisman J. Research perspective: potential role of nitazoxanide in ovarian cancer treatment. Old drug, new purpose?. Cancers (Basel) 2013, 5(3):1163-1176.
    • (2013) Cancers (Basel) , vol.5 , Issue.3 , pp. 1163-1176
    • Di Santo, N.1    Ehrisman, J.2
  • 68
    • 0017231098 scopus 로고
    • Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine
    • Doberstyn E.B., Hall A.P., Vetvutanapibul K., Sonkon P. Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. Am. J. Trop. Med. Hyg. 1976, 25(1):14-19.
    • (1976) Am. J. Trop. Med. Hyg. , vol.25 , Issue.1 , pp. 14-19
    • Doberstyn, E.B.1    Hall, A.P.2    Vetvutanapibul, K.3    Sonkon, P.4
  • 69
    • 84880926027 scopus 로고    scopus 로고
    • Artemisinin resistance is a clear and present danger
    • Dondorp A.M., Ringwald P. Artemisinin resistance is a clear and present danger. Trends Parasitol. 2013, 29(8):359-360.
    • (2013) Trends Parasitol. , vol.29 , Issue.8 , pp. 359-360
    • Dondorp, A.M.1    Ringwald, P.2
  • 71
    • 84867610036 scopus 로고    scopus 로고
    • Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
    • Dorlo T.P., Balasegaram M., Beijnen J.H., de Vries P.J. Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis. J. Antimicrob. Chemother. 2012, 67(11):2576-2597.
    • (2012) J. Antimicrob. Chemother. , vol.67 , Issue.11 , pp. 2576-2597
    • Dorlo, T.P.1    Balasegaram, M.2    Beijnen, J.H.3    de Vries, P.J.4
  • 73
    • 34548304745 scopus 로고    scopus 로고
    • In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling
    • Ekins S., Mestres J., Testa B. In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling. Br. J. Pharmacol. 2007, 152(1):9-20.
    • (2007) Br. J. Pharmacol. , vol.152 , Issue.1 , pp. 9-20
    • Ekins, S.1    Mestres, J.2    Testa, B.3
  • 74
    • 70350125916 scopus 로고    scopus 로고
    • The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation
    • Elazar M., Liu M., McKenna S.A., Liu P., Gehrig E.A., Puglisi J.D., Rossignol J.F., Glenn J.S. The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation. Gastroenterology 2009, 137(5):1827-1835.
    • (2009) Gastroenterology , vol.137 , Issue.5 , pp. 1827-1835
    • Elazar, M.1    Liu, M.2    McKenna, S.A.3    Liu, P.4    Gehrig, E.A.5    Puglisi, J.D.6    Rossignol, J.F.7    Glenn, J.S.8
  • 75
    • 77955402138 scopus 로고    scopus 로고
    • Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease
    • Engel J.C., Ang K.K., Chen S., Arkin M.R., McKerrow J.H., Doyle P.S. Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease. Antimicrob. Agents Chemother. 2010, 54(8):3326-3334.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , Issue.8 , pp. 3326-3334
    • Engel, J.C.1    Ang, K.K.2    Chen, S.3    Arkin, M.R.4    McKerrow, J.H.5    Doyle, P.S.6
  • 77
    • 0026537075 scopus 로고
    • Azithromycin for cerebral toxoplasmosis
    • Farthing C., Rendel M., Currie B., Seidlin M. Azithromycin for cerebral toxoplasmosis. Lancet 1992, 339(8790):437-438.
    • (1992) Lancet , vol.339 , Issue.8790 , pp. 437-438
    • Farthing, C.1    Rendel, M.2    Currie, B.3    Seidlin, M.4
  • 78
    • 2942620300 scopus 로고    scopus 로고
    • Increased risk of traffic accidents in subjects with latent toxoplasmosis: a retrospective case-control study
    • Flegr J., Havlicek J., Kodym P., Maly M., Smahel Z. Increased risk of traffic accidents in subjects with latent toxoplasmosis: a retrospective case-control study. BMC Infect. Dis. 2002, 2:11.
    • (2002) BMC Infect. Dis. , vol.2 , pp. 11
    • Flegr, J.1    Havlicek, J.2    Kodym, P.3    Maly, M.4    Smahel, Z.5
  • 79
    • 67649687838 scopus 로고    scopus 로고
    • Increased incidence of traffic accidents in Toxoplasma-infected military drivers and protective effect RhD molecule revealed by a large-scale prospective cohort study
    • Flegr J., Klose J., Novotna M., Berenreitterova M., Havlicek J. Increased incidence of traffic accidents in Toxoplasma-infected military drivers and protective effect RhD molecule revealed by a large-scale prospective cohort study. BMC Infect. Dis. 2009, 9:72.
    • (2009) BMC Infect. Dis. , vol.9 , pp. 72
    • Flegr, J.1    Klose, J.2    Novotna, M.3    Berenreitterova, M.4    Havlicek, J.5
  • 80
    • 0000240697 scopus 로고
    • Mel B in the treatment of human trypanosomiasis
    • Friedheim E.A. Mel B in the treatment of human trypanosomiasis. Am. J. Trop. Med. Hyg. 1949, 29(2):173-180.
    • (1949) Am. J. Trop. Med. Hyg. , vol.29 , Issue.2 , pp. 173-180
    • Friedheim, E.A.1
  • 82
    • 77953023715 scopus 로고    scopus 로고
    • Chagas disease in Spain, the United States and other non-endemic countries
    • Gascon J., Bern C., Pinazo M.J. Chagas disease in Spain, the United States and other non-endemic countries. Acta Trop. 2010, 115(1-2):22-27.
    • (2010) Acta Trop. , vol.115 , Issue.1-2 , pp. 22-27
    • Gascon, J.1    Bern, C.2    Pinazo, M.J.3
  • 83
    • 0028029323 scopus 로고
    • Management of toxoplasmosis
    • Georgiev V.S. Management of toxoplasmosis. Drugs 1994, 48(2):179-188.
    • (1994) Drugs , vol.48 , Issue.2 , pp. 179-188
    • Georgiev, V.S.1
  • 84
    • 0018399276 scopus 로고
    • Drug therapy reviews: trimethoprim-sulfamethoxazole
    • Gleckman R., Alvarez S., Joubert D.W. Drug therapy reviews: trimethoprim-sulfamethoxazole. Am. J. Hosp. Pharm. 1979, 36(7):893-906.
    • (1979) Am. J. Hosp. Pharm. , vol.36 , Issue.7 , pp. 893-906
    • Gleckman, R.1    Alvarez, S.2    Joubert, D.W.3
  • 85
    • 84884534575 scopus 로고    scopus 로고
    • Drug library screening against metronidazole-sensitive and metronidazole-resistant Trichomonas vaginalis isolates
    • Goodhew E.B., Secor W.E. Drug library screening against metronidazole-sensitive and metronidazole-resistant Trichomonas vaginalis isolates. Sex. Transm. Infect. 2013, 89(6):479-484.
    • (2013) Sex. Transm. Infect. , vol.89 , Issue.6 , pp. 479-484
    • Goodhew, E.B.1    Secor, W.E.2
  • 86
    • 57149107850 scopus 로고    scopus 로고
    • Traversal of human and animal trypanosomes across the blood-brain barrier
    • Grab D.J., Kennedy P.G. Traversal of human and animal trypanosomes across the blood-brain barrier. J. Neurovirol. 2008, 14(5):344-351.
    • (2008) J. Neurovirol. , vol.14 , Issue.5 , pp. 344-351
    • Grab, D.J.1    Kennedy, P.G.2
  • 88
    • 0032709747 scopus 로고    scopus 로고
    • Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four-seven years later in a poor urban community in northeast Brazil
    • Guerrant D.I., Moore S.R., Lima A.A., Patrick P.D., Schorling J.B., Guerrant R.L. Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four-seven years later in a poor urban community in northeast Brazil. Am. J. Trop. Med. Hyg. 1999, 61(5):707-713.
    • (1999) Am. J. Trop. Med. Hyg. , vol.61 , Issue.5 , pp. 707-713
    • Guerrant, D.I.1    Moore, S.R.2    Lima, A.A.3    Patrick, P.D.4    Schorling, J.B.5    Guerrant, R.L.6
  • 90
    • 0035100870 scopus 로고    scopus 로고
    • Human dermal safety studies with eflornithine HCl 13.9% cream (Vaniqa), a novel treatment for excessive facial hair
    • Hickman J.G., Huber F., Palmisano M. Human dermal safety studies with eflornithine HCl 13.9% cream (Vaniqa), a novel treatment for excessive facial hair. Curr. Med. Res. Opin. 2001, 16(4):235-244.
    • (2001) Curr. Med. Res. Opin. , vol.16 , Issue.4 , pp. 235-244
    • Hickman, J.G.1    Huber, F.2    Palmisano, M.3
  • 91
    • 84857809426 scopus 로고    scopus 로고
    • Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases
    • Hotez P. Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases. Vaccine 2011, 29(Suppl. 4):D104-D110.
    • (2011) Vaccine , vol.29 , Issue.SUPPL. 4
    • Hotez, P.1
  • 94
    • 79955428497 scopus 로고    scopus 로고
    • The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
    • 80ps16
    • Huang R., Southall N., Wang Y., Yasgar A., Shinn P., Jadhav A., Nguyen D.T., Austin C.P. The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics. Sci. Transl. Med. 2011, 3(80):80ps16.
    • (2011) Sci. Transl. Med. , vol.3 , Issue.80
    • Huang, R.1    Southall, N.2    Wang, Y.3    Yasgar, A.4    Shinn, P.5    Jadhav, A.6    Nguyen, D.T.7    Austin, C.P.8
  • 95
    • 0030824384 scopus 로고    scopus 로고
    • Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to d,l-alpha-difluoromethylornithine
    • Iten M., Mett H., Evans A., Enyaru J.C., Brun R., Kaminsky R. Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to d,l-alpha-difluoromethylornithine. Antimicrob. Agents Chemother. 1997, 41(9):1922-1925.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , Issue.9 , pp. 1922-1925
    • Iten, M.1    Mett, H.2    Evans, A.3    Enyaru, J.C.4    Brun, R.5    Kaminsky, R.6
  • 98
    • 80053459547 scopus 로고    scopus 로고
    • Innovative partnerships for drug discovery against neglected diseases
    • Jakobsen P.H., Wang M.W., Nwaka S. Innovative partnerships for drug discovery against neglected diseases. PLoS Negl. Trop. Dis. 2011, 5(9):e1221.
    • (2011) PLoS Negl. Trop. Dis. , vol.5 , Issue.9
    • Jakobsen, P.H.1    Wang, M.W.2    Nwaka, S.3
  • 99
    • 84876759859 scopus 로고    scopus 로고
    • Whole-organism high-throughput screening against Trypanosoma brucei brucei
    • Jones A.J., Avery V.M. Whole-organism high-throughput screening against Trypanosoma brucei brucei. Expert Opin. Drug Discov. 2013, 8(5):495-507.
    • (2013) Expert Opin. Drug Discov. , vol.8 , Issue.5 , pp. 495-507
    • Jones, A.J.1    Avery, V.M.2
  • 100
    • 0029785787 scopus 로고    scopus 로고
    • Risk factors for Toxoplasma gondii infection in pregnancy. Results of a prospective case-control study in Norway
    • Kapperud G., Jenum P.A., Stray-Pedersen B., Melby K.K., Eskild A., Eng J. Risk factors for Toxoplasma gondii infection in pregnancy. Results of a prospective case-control study in Norway. Am. J. Epidemiol. 1996, 144(4):405-412.
    • (1996) Am. J. Epidemiol. , vol.144 , Issue.4 , pp. 405-412
    • Kapperud, G.1    Jenum, P.A.2    Stray-Pedersen, B.3    Melby, K.K.4    Eskild, A.5    Eng, J.6
  • 101
    • 84874263173 scopus 로고    scopus 로고
    • Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffolds
    • Katiyar S., Kufareva I., Behera R., Thomas S.M., Ogata Y., Pollastri M., Abagyan R., Mensa-Wilmot K. Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffolds. PLoS ONE 2013, 8(2):e56150.
    • (2013) PLoS ONE , vol.8 , Issue.2
    • Katiyar, S.1    Kufareva, I.2    Behera, R.3    Thomas, S.M.4    Ogata, Y.5    Pollastri, M.6    Abagyan, R.7    Mensa-Wilmot, K.8
  • 102
    • 84965088820 scopus 로고
    • A study of experimental cutaneous leishmaniasis in white mice
    • Kellina O.I. A study of experimental cutaneous leishmaniasis in white mice. Med. Parazitol. (Mosk). 1961, 30:684-691.
    • (1961) Med. Parazitol. (Mosk). , vol.30 , pp. 684-691
    • Kellina, O.I.1
  • 103
    • 84857369836 scopus 로고    scopus 로고
    • Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei
    • Kelly J.M., Taylor M.C., Horn D., Loza E., Kalvinsh I., Bjorkling F. Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei. Bioorg. Med. Chem. Lett. 2012, 22(5):1886-1890.
    • (2012) Bioorg. Med. Chem. Lett. , vol.22 , Issue.5 , pp. 1886-1890
    • Kelly, J.M.1    Taylor, M.C.2    Horn, D.3    Loza, E.4    Kalvinsh, I.5    Bjorkling, F.6
  • 104
    • 51549108736 scopus 로고    scopus 로고
    • The continuing problem of human African trypanosomiasis (sleeping sickness)
    • Kennedy P.G. The continuing problem of human African trypanosomiasis (sleeping sickness). Ann. Neurol. 2008, 64(2):116-126.
    • (2008) Ann. Neurol. , vol.64 , Issue.2 , pp. 116-126
    • Kennedy, P.G.1
  • 105
    • 84872373862 scopus 로고    scopus 로고
    • Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness)
    • Kennedy P.G. Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness). Lancet Neurol. 2013, 12(2):186-194.
    • (2013) Lancet Neurol. , vol.12 , Issue.2 , pp. 186-194
    • Kennedy, P.G.1
  • 106
    • 0021948029 scopus 로고
    • Qinghaosu (artemisinin): an antimalarial drug from China
    • Klayman D.L. Qinghaosu (artemisinin): an antimalarial drug from China. Science 1985, 228(4703):1049-1055.
    • (1985) Science , vol.228 , Issue.4703 , pp. 1049-1055
    • Klayman, D.L.1
  • 109
    • 10444281634 scopus 로고    scopus 로고
    • Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?
    • Krungkrai J., Scozzafava A., Reungprapavut S., Krungkrai S.R., Rattanajak R., Kamchonwongpaisan S., Supuran C.T. Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?. Bioorg. Med. Chem. 2005, 13(2):483-489.
    • (2005) Bioorg. Med. Chem. , vol.13 , Issue.2 , pp. 483-489
    • Krungkrai, J.1    Scozzafava, A.2    Reungprapavut, S.3    Krungkrai, S.R.4    Rattanajak, R.5    Kamchonwongpaisan, S.6    Supuran, C.T.7
  • 110
    • 53549094659 scopus 로고    scopus 로고
    • Carbonic anhydrase inhibitors: inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides-in vitro and in vivo studies
    • Krungkrai J., Krungkrai S.R., Supuran C.T. Carbonic anhydrase inhibitors: inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides-in vitro and in vivo studies. Bioorg. Med. Chem. Lett. 2008, 18(20):5466-5471.
    • (2008) Bioorg. Med. Chem. Lett. , vol.18 , Issue.20 , pp. 5466-5471
    • Krungkrai, J.1    Krungkrai, S.R.2    Supuran, C.T.3
  • 111
    • 84875614866 scopus 로고    scopus 로고
    • Global economic burden of Chagas disease: a computational simulation model
    • Lee B.Y., Bacon K.M., Bottazzi M.E., Hotez P.J. Global economic burden of Chagas disease: a computational simulation model. Lancet Infect. Dis. 2013, 13(4):342-348.
    • (2013) Lancet Infect. Dis. , vol.13 , Issue.4 , pp. 342-348
    • Lee, B.Y.1    Bacon, K.M.2    Bottazzi, M.E.3    Hotez, P.J.4
  • 112
    • 0023934097 scopus 로고
    • Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy
    • Leport C., Raffi F., Matheron S., Katlama C., Regnier B., Saimot A.G., Marche C., Vedrenne C., Vilde J.L. Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy. Am. J. Med. 1988, 84(1):94-100.
    • (1988) Am. J. Med. , vol.84 , Issue.1 , pp. 94-100
    • Leport, C.1    Raffi, F.2    Matheron, S.3    Katlama, C.4    Regnier, B.5    Saimot, A.G.6    Marche, C.7    Vedrenne, C.8    Vilde, J.L.9
  • 113
    • 0033509735 scopus 로고    scopus 로고
    • Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani
    • Lira R., Sundar S., Makharia A., Kenney R., Gam A., Saraiva E., Sacks D. Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani. J. Infect. Dis. 1999, 180(2):564-567.
    • (1999) J. Infect. Dis. , vol.180 , Issue.2 , pp. 564-567
    • Lira, R.1    Sundar, S.2    Makharia, A.3    Kenney, R.4    Gam, A.5    Saraiva, E.6    Sacks, D.7
  • 114
    • 84975019637 scopus 로고
    • Studies in chemotherapy. XVI. The trypanocidal action of synthalin
    • Lourie E., Yorke W. Studies in chemotherapy. XVI. The trypanocidal action of synthalin. Ann. Trop. Med. Parasitol. 1937, 31:435-445.
    • (1937) Ann. Trop. Med. Parasitol. , vol.31 , pp. 435-445
    • Lourie, E.1    Yorke, W.2
  • 116
    • 84871041926 scopus 로고    scopus 로고
    • Plasmodium kinases as targets for new-generation antimalarials
    • Lucet I.S., Tobin A., Drewry D., Wilks A.F., Doerig C. Plasmodium kinases as targets for new-generation antimalarials. Future Med. Chem. 2012, 4(18):2295-2310.
    • (2012) Future Med. Chem. , vol.4 , Issue.18 , pp. 2295-2310
    • Lucet, I.S.1    Tobin, A.2    Drewry, D.3    Wilks, A.F.4    Doerig, C.5
  • 117
    • 0026901767 scopus 로고
    • Toxoplasmic encephalitis in AIDS
    • Luft B.J., Remington J.S. Toxoplasmic encephalitis in AIDS. Clin. Infect. Dis. 1992, 15(2):211-222.
    • (1992) Clin. Infect. Dis. , vol.15 , Issue.2 , pp. 211-222
    • Luft, B.J.1    Remington, J.S.2
  • 119
    • 0031055981 scopus 로고    scopus 로고
    • Biochemical alterations in paromomycin-treated Leishmania donovani promastigotes
    • Maarouf M., Lawrence F., Brown S., Robert-Gero M. Biochemical alterations in paromomycin-treated Leishmania donovani promastigotes. Parasitol. Res. 1997, 83(2):198-202.
    • (1997) Parasitol. Res. , vol.83 , Issue.2 , pp. 198-202
    • Maarouf, M.1    Lawrence, F.2    Brown, S.3    Robert-Gero, M.4
  • 122
    • 84874304359 scopus 로고    scopus 로고
    • Safety and efficacy of co-trimoxazole for treatment and prevention of Plasmodium falciparum malaria: a systematic review
    • Manyando C., Njunju E.M., D'Alessandro U., Van Geertruyden J.P. Safety and efficacy of co-trimoxazole for treatment and prevention of Plasmodium falciparum malaria: a systematic review. PLoS ONE 2013, 8(2):e56916.
    • (2013) PLoS ONE , vol.8 , Issue.2
    • Manyando, C.1    Njunju, E.M.2    D'Alessandro, U.3    Van Geertruyden, J.P.4
  • 124
    • 85015294644 scopus 로고    scopus 로고
    • Combination therapy with nitazoxanide and amphotericin B, Glucantime, miltefosine and sitamaquine against Leishmania (Leishmania) infantum intracellular amastigotes
    • Mesquita J.T., Tempone A.G., Reimao J.Q. Combination therapy with nitazoxanide and amphotericin B, Glucantime, miltefosine and sitamaquine against Leishmania (Leishmania) infantum intracellular amastigotes. Acta Trop. 2013.
    • (2013) Acta Trop.
    • Mesquita, J.T.1    Tempone, A.G.2    Reimao, J.Q.3
  • 125
    • 0032991693 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration approval of Am Bisome (liposomal amphotericin B) for treatment of visceral leishmaniasis
    • discussion 49-51
    • Meyerhoff A. U.S. Food and Drug Administration approval of Am Bisome (liposomal amphotericin B) for treatment of visceral leishmaniasis. Clin. Infect. Dis. 1999, 28(1):42-48. discussion 49-51.
    • (1999) Clin. Infect. Dis. , vol.28 , Issue.1 , pp. 42-48
    • Meyerhoff, A.1
  • 126
    • 0016220150 scopus 로고
    • Evaluation of clindamycin in combination with quinine against multidrug-resistant strains of Plasmodium falciparum
    • Miller L.H., Glew R.H., Wyler D.J., Howard W.A., Collins W.E., Contacos P.G., Neva F.A. Evaluation of clindamycin in combination with quinine against multidrug-resistant strains of Plasmodium falciparum. Am. J. Trop. Med. Hyg. 1974, 23(4):565-569.
    • (1974) Am. J. Trop. Med. Hyg. , vol.23 , Issue.4 , pp. 565-569
    • Miller, L.H.1    Glew, R.H.2    Wyler, D.J.3    Howard, W.A.4    Collins, W.E.5    Contacos, P.G.6    Neva, F.A.7
  • 127
    • 34248369669 scopus 로고    scopus 로고
    • Artemisinins inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense in vitro growth
    • Mishina Y.V., Krishna S., Haynes R.K., Meade J.C. Artemisinins inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense in vitro growth. Antimicrob. Agents Chemother. 2007, 51(5):1852-1854.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , Issue.5 , pp. 1852-1854
    • Mishina, Y.V.1    Krishna, S.2    Haynes, R.K.3    Meade, J.C.4
  • 128
    • 0021367819 scopus 로고
    • Clinical trial of nifurtimox in human African trypanosomiasis
    • Moens F., De Wilde M., Ngato K. Clinical trial of nifurtimox in human African trypanosomiasis. Ann. Soc. Belg. Med. Trop. 1984, 64(1):37-43.
    • (1984) Ann. Soc. Belg. Med. Trop. , vol.64 , Issue.1 , pp. 37-43
    • Moens, F.1    De Wilde, M.2    Ngato, K.3
  • 129
    • 2942541583 scopus 로고    scopus 로고
    • Toxoplasmosis
    • Montoya J.G., Liesenfeld O. Toxoplasmosis. Lancet 2004, 363(9425):1965-1976.
    • (2004) Lancet , vol.363 , Issue.9425 , pp. 1965-1976
    • Montoya, J.G.1    Liesenfeld, O.2
  • 130
    • 79957918070 scopus 로고    scopus 로고
    • Could pharma open its drug freezers?
    • Mullard A. Could pharma open its drug freezers?. Nat. Rev. Drug Discov. 2011, 10(6):399-400.
    • (2011) Nat. Rev. Drug Discov. , vol.10 , Issue.6 , pp. 399-400
    • Mullard, A.1
  • 131
    • 84863204946 scopus 로고    scopus 로고
    • Drug repurposing programmes get lift off
    • Mullard A. Drug repurposing programmes get lift off. Nat. Rev. Drug Discov. 2012, 11(7):505-506.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , Issue.7 , pp. 505-506
    • Mullard, A.1
  • 132
    • 37349023592 scopus 로고    scopus 로고
    • Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides
    • Muller J., Naguleswaran A., Muller N., Hemphill A. Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides. Exp. Parasitol. 2008, 118(1):80-88.
    • (2008) Exp. Parasitol. , vol.118 , Issue.1 , pp. 80-88
    • Muller, J.1    Naguleswaran, A.2    Muller, N.3    Hemphill, A.4
  • 133
    • 51949104566 scopus 로고    scopus 로고
    • Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells
    • Muller J., Sidler D., Nachbur U., Wastling J., Brunner T., Hemphill A. Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells. Int. J. Cancer 2008, 123(8):1797-1806.
    • (2008) Int. J. Cancer , vol.123 , Issue.8 , pp. 1797-1806
    • Muller, J.1    Sidler, D.2    Nachbur, U.3    Wastling, J.4    Brunner, T.5    Hemphill, A.6
  • 135
    • 84883100343 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and other autoimmune rheumatic diseases: challenges to treatment
    • Murphy G., Lisnevskaia L., Isenberg D. Systemic lupus erythematosus and other autoimmune rheumatic diseases: challenges to treatment. Lancet 2013, 382(9894):809-818.
    • (2013) Lancet , vol.382 , Issue.9894 , pp. 809-818
    • Murphy, G.1    Lisnevskaia, L.2    Isenberg, D.3
  • 137
    • 84871099014 scopus 로고    scopus 로고
    • Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
    • Murray C.J., Vos T., Lozano R., Naghavi M., Flaxman A.D., Michaud C., Ezzati M., Shibuya K., Salomon J.A., Abdalla S., Aboyans V., Abraham J., Ackerman I., Aggarwal R., Ahn S.Y., Ali M.K., Alvarado M., Anderson H.R., Anderson L.M., Andrews K.G., Atkinson C., Baddour L.M., Bahalim A.N., Barker-Collo S., Barrero L.H., Bartels D.H., Basanez M.G., Baxter A., Bell M.L., Benjamin E.J., Bennett D., Bernabe E., Bhalla K., Bhandari B., Bikbov B., Bin Abdulhak A., Birbeck G., Black J.A., Blencowe H., Blore J.D., Blyth F., Bolliger I., Bonaventure A., Boufous S., Bourne R., Boussinesq M., Braithwaite T., Brayne C., Bridgett L., Brooker S., Brooks P., Brugha T.S., Bryan-Hancock C., Bucello C., Buchbinder R., Buckle G., Budke C.M., Burch M., Burney P., Burstein R., Calabria B., Campbell B., Canter C.E., Carabin H., Carapetis J., Carmona L., Cella C., Charlson F., Chen H., Cheng A.T., Chou D., Chugh S.S., Coffeng L.E., Colan S.D., Colquhoun S., Colson K.E., Condon J., Connor M.D., Cooper L.T., Corriere M., Cortinovis M., de Vaccaro K.C., Couser W., Cowie B.C., Criqui M.H., Cross M., Dabhadkar K.C., Dahiya M., Dahodwala N., Damsere-Derry J., Danaei G., Davis A., De Leo D., Degenhardt L., Dellavalle R., Delossantos A., Denenberg J., Derrett S., Des Jarlais D.C., Dharmaratne S.D., Dherani M., Diaz-Torne C., Dolk H., Dorsey E.R., Driscoll T., Duber H., Ebel B., Edmond K., Elbaz A., Ali S.E., Erskine H., Erwin P.J., Espindola P., Ewoigbokhan S.E., Farzadfar F., Feigin V., Felson D.T., Ferrari A., Ferri C.P., Fevre E.M., Finucane M.M., Flaxman S., Flood L., Foreman K., Forouzanfar M.H., Fowkes F.G., Fransen M., Freeman M.K., Gabbe B.J., Gabriel S.E., Gakidou E., Ganatra H.A., Garcia B., Gaspari F., Gillum R.F., Gmel G., Gonzalez-Medina D., Gosselin R., Grainger R., Grant B., Groeger J., Guillemin F., Gunnell D., Gupta R., Haagsma J., Hagan H., Halasa Y.A., Hall W., Haring D., Haro J.M., Harrison J.E., Havmoeller R., Hay R.J., Higashi H., Hill C., Hoen B., Hoffman H., Hotez P.J., Hoy D., Huang J.J., Ibeanusi S.E., Jacobsen K.H., James S.L., Jarvis D., Jasrasaria R., Jayaraman S., Johns N., Jonas J.B., Karthikeyan G., Kassebaum N., Kawakami N., Keren A., Khoo J.P., King C.H., Knowlton L.M., Kobusingye O., Koranteng A., Krishnamurthi R., Laden F., Lalloo R., Laslett L.L., Lathlean T., Leasher J.L., Lee Y.Y., Leigh J., Levinson D., Lim S.S., Limb E., Lin J.K., Lipnick M., Lipshultz S.E., Liu W., Loane M., Ohno S.L., Lyons R., Mabweijano J., MacIntyre M.F., Malekzadeh R., Mallinger L., Manivannan S., Marcenes W., March L., Margolis D.J., Marks G.B., Marks R., Matsumori A., Matzopoulos R., Mayosi B.M., McAnulty J.H., McDermott M.M., McGill N., McGrath J., Medina-Mora M.E., Meltzer M., Mensah G.A., Merriman T.R., Meyer A.C., Miglioli V., Miller M., Miller T.R., Mitchell P.B., Mock C., Mocumbi A.O., Moffitt T.E., Mokdad A.A., Monasta L., Montico M., Moradi-Lakeh M., Moran A., Morawska L., Mori R., Murdoch M.E., Mwaniki M.K., Naidoo K., Nair M.N., Naldi L., Narayan K.M., Nelson P.K., Nelson R.G., Nevitt M.C., Newton C.R., Nolte S., Norman P., Norman R., O'Donnell M., O'Hanlon S., Olives C., Omer S.B., Ortblad K., Osborne R., Ozgediz D., Page A., Pahari B., Pandian J.D., Rivero A.P., Patten S.B., Pearce N., Padilla R.P., Perez-Ruiz F., Perico N., Pesudovs K., Phillips D., Phillips M.R., Pierce K., Pion S., Polanczyk G.V., Polinder S., Pope C.A., Popova S., Porrini E., Pourmalek F., Prince M., Pullan R.L., Ramaiah K.D., Ranganathan D., Razavi H., Regan M., Rehm J.T., Rein D.B., Remuzzi G., Richardson K., Rivara F.P., Roberts T., Robinson C., De Leon F.R., Ronfani L., Room R., Rosenfeld L.C., Rushton L., Sacco R.L., Saha S., Sampson U., Sanchez-Riera L., Sanman E., Schwebel D.C., Scott J.G., Segui-Gomez M., Shahraz S., Shepard D.S., Shin H., Shivakoti R., Singh D., Singh G.M., Singh J.A., Singleton J., Sleet D.A., Sliwa K., Smith E., Smith J.L., Stapelberg N.J., Steer A., Steiner T., Stolk W.A., Stovner L.J., Sudfeld C., Syed S., Tamburlini G., Tavakkoli M., Taylor H.R., Taylor J.A., Taylor W.J., Thomas B., Thomson W.M., Thurston G.D., Tleyjeh I.M., Tonelli M., Towbin J.A., Truelsen T., Tsilimbaris M.K., Ubeda C., Undurraga E.A., van der Werf M.J., van Os J., Vavilala M.S., Venketasubramanian N., Wang M., Wang W., Watt K., Weatherall D.J., Weinstock M.A., Weintraub R., Weisskopf M.G., Weissman M.M., White R.A., Whiteford H., Wiebe N., Wiersma S.T., Wilkinson J.D., Williams H.C., Williams S.R., Witt E., Wolfe F., Woolf A.D., Wulf S., Yeh P.H., Zaidi A.K., Zheng Z.J., Zonies D., Lopez A.D., AlMazroa M.A., Memish Z.A. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012, 380(9859):2197-2223.
    • (2012) Lancet , vol.380 , Issue.9859 , pp. 2197-2223
    • Murray, C.J.1    Vos, T.2    Lozano, R.3    Naghavi, M.4    Flaxman, A.D.5    Michaud, C.6    Ezzati, M.7    Shibuya, K.8    Salomon, J.A.9    Abdalla, S.10    Aboyans, V.11    Abraham, J.12    Ackerman, I.13    Aggarwal, R.14    Ahn, S.Y.15    Ali, M.K.16    Alvarado, M.17    Anderson, H.R.18    Anderson, L.M.19    Andrews, K.G.20    more..
  • 138
    • 17344379918 scopus 로고    scopus 로고
    • Molecular characterization of susceptible and naturally resistant strains of Trypanosoma cruzi to benznidazole and nifurtimox
    • Murta S.M., Gazzinelli R.T., Brener Z., Romanha A.J. Molecular characterization of susceptible and naturally resistant strains of Trypanosoma cruzi to benznidazole and nifurtimox. Mol. Biochem. Parasitol. 1998, 93(2):203-214.
    • (1998) Mol. Biochem. Parasitol. , vol.93 , Issue.2 , pp. 203-214
    • Murta, S.M.1    Gazzinelli, R.T.2    Brener, Z.3    Romanha, A.J.4
  • 139
  • 140
    • 0026542263 scopus 로고
    • Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala
    • Navin T.R., Arana B.A., Arana F.E., Berman J.D., Chajon J.F. Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala. J. Infect. Dis. 1992, 165(3):528-534.
    • (1992) J. Infect. Dis. , vol.165 , Issue.3 , pp. 528-534
    • Navin, T.R.1    Arana, B.A.2    Arana, F.E.3    Berman, J.D.4    Chajon, J.F.5
  • 141
    • 0014256575 scopus 로고
    • The effect of antibiotics of the neomycin group on experimental cutaneous leishmaniasis
    • Neal R.A. The effect of antibiotics of the neomycin group on experimental cutaneous leishmaniasis. Ann. Trop. Med. Parasitol. 1968, 62(1):54-62.
    • (1968) Ann. Trop. Med. Parasitol. , vol.62 , Issue.1 , pp. 54-62
    • Neal, R.A.1
  • 143
    • 33749441465 scopus 로고    scopus 로고
    • Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease
    • Nikolskaia O.V., de A.L.A.P., Kim Y.V., Lonsdale-Eccles J.D., Fukuma T., Scharfstein J., Grab D.J. Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease. J. Clin. Invest. 2006, 116(10):2739-2747.
    • (2006) J. Clin. Invest. , vol.116 , Issue.10 , pp. 2739-2747
    • Nikolskaia, O.V.1    de, A.L.A.P.2    Kim, Y.V.3    Lonsdale-Eccles, J.D.4    Fukuma, T.5    Scharfstein, J.6    Grab, D.J.7
  • 144
    • 84866643099 scopus 로고    scopus 로고
    • Artemisinin derivatives: a patent review (2006 - present)
    • Njuguna N.M., Ongarora D.S., Chibale K. Artemisinin derivatives: a patent review (2006 - present). Expert Opin. Ther. Pat. 2012, 22(10):1179-1203.
    • (2012) Expert Opin. Ther. Pat. , vol.22 , Issue.10 , pp. 1179-1203
    • Njuguna, N.M.1    Ongarora, D.S.2    Chibale, K.3
  • 145
    • 84882785178 scopus 로고    scopus 로고
    • Chagas disease: an overview of clinical and epidemiological aspects
    • Council on Chagas Disease of the Interamerican Society of Cardiology
    • Nunes M.C., Dones W., Morillo C.A., Encina J.J., Ribeiro A.L., Council on Chagas Disease of the Interamerican Society of Cardiology Chagas disease: an overview of clinical and epidemiological aspects. J. Am. Coll. Cardiol. 2013, 62(9):767-776.
    • (2013) J. Am. Coll. Cardiol. , vol.62 , Issue.9 , pp. 767-776
    • Nunes, M.C.1    Dones, W.2    Morillo, C.A.3    Encina, J.J.4    Ribeiro, A.L.5
  • 146
    • 33750531864 scopus 로고    scopus 로고
    • Innovative lead discovery strategies for tropical diseases
    • Nwaka S., Hudson A. Innovative lead discovery strategies for tropical diseases. Nat. Rev. Drug Discov. 2006, 5(11):941-955.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.11 , pp. 941-955
    • Nwaka, S.1    Hudson, A.2
  • 147
    • 84888094480 scopus 로고    scopus 로고
    • Small molecule kinase inhibitors approved by the FDA from 2000 to 2011: a systematic review of preclinical ADME data
    • O'Brien Z., Fallah Moghaddam M. Small molecule kinase inhibitors approved by the FDA from 2000 to 2011: a systematic review of preclinical ADME data. Expert Opin. Drug Metab. Toxicol. 2013, 9(12):1597-1612.
    • (2013) Expert Opin. Drug Metab. Toxicol. , vol.9 , Issue.12 , pp. 1597-1612
    • O'Brien, Z.1    Fallah Moghaddam, M.2
  • 148
    • 84876033143 scopus 로고    scopus 로고
    • The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing
    • Ochiana S.O., Pandarinath V., Wang Z., Kapoor R., Ondrechen M.J., Ruben L., Pollastri M.P. The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing. Eur. J. Med. Chem. 2013, 62:777-784.
    • (2013) Eur. J. Med. Chem. , vol.62 , pp. 777-784
    • Ochiana, S.O.1    Pandarinath, V.2    Wang, Z.3    Kapoor, R.4    Ondrechen, M.J.5    Ruben, L.6    Pollastri, M.P.7
  • 149
    • 5644245285 scopus 로고    scopus 로고
    • Management of children with infection-associated persistent diarrhea
    • Ochoa T.J., Salazar-Lindo E., Cleary T.G. Management of children with infection-associated persistent diarrhea. Semin. Pediatr. Infect. Dis. 2004, 15(4):229-236.
    • (2004) Semin. Pediatr. Infect. Dis. , vol.15 , Issue.4 , pp. 229-236
    • Ochoa, T.J.1    Salazar-Lindo, E.2    Cleary, T.G.3
  • 150
    • 84874964102 scopus 로고    scopus 로고
    • Artemether and lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa
    • Ogutu B. Artemether and lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa. Expert Opin. Pharmacother. 2013, 14(5):643-654.
    • (2013) Expert Opin. Pharmacother. , vol.14 , Issue.5 , pp. 643-654
    • Ogutu, B.1
  • 152
    • 0030996657 scopus 로고    scopus 로고
    • A randomized clinical trial of topical paromomycin versus oral ketoconazole for treating cutaneous leishmaniasis in Turkey
    • Ozgoztasi O., Baydar I. A randomized clinical trial of topical paromomycin versus oral ketoconazole for treating cutaneous leishmaniasis in Turkey. Int. J. Dermatol. 1997, 36(1):61-63.
    • (1997) Int. J. Dermatol. , vol.36 , Issue.1 , pp. 61-63
    • Ozgoztasi, O.1    Baydar, I.2
  • 153
    • 84898010996 scopus 로고    scopus 로고
    • Paladin Labs Inc, Application for Inclusion of Miltefosine on WHO. Model List of Essential Medicines.
    • Paladin Labs Inc, 2010. Application for Inclusion of Miltefosine on WHO. Model List of Essential Medicines.
    • (2010)
  • 154
    • 35548984903 scopus 로고    scopus 로고
    • Meta-analysis of three case controlled studies and an ecological study into the link between cryptogenic epilepsy and chronic toxoplasmosis infection
    • Palmer B.S. Meta-analysis of three case controlled studies and an ecological study into the link between cryptogenic epilepsy and chronic toxoplasmosis infection. Seizure 2007, 16(8):657-663.
    • (2007) Seizure , vol.16 , Issue.8 , pp. 657-663
    • Palmer, B.S.1
  • 155
    • 84874592654 scopus 로고    scopus 로고
    • Cloning, characterization, and sulfonamide and thiol inhibition studies of an alpha-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease
    • Pan P., Vermelho A.B., Capaci Rodrigues G., Scozzafava A., Tolvanen M.E., Parkkila S., Capasso C., Supuran C.T. Cloning, characterization, and sulfonamide and thiol inhibition studies of an alpha-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. J. Med. Chem. 2013, 56(4):1761-1771.
    • (2013) J. Med. Chem. , vol.56 , Issue.4 , pp. 1761-1771
    • Pan, P.1    Vermelho, A.B.2    Capaci Rodrigues, G.3    Scozzafava, A.4    Tolvanen, M.E.5    Parkkila, S.6    Capasso, C.7    Supuran, C.T.8
  • 156
    • 84878042492 scopus 로고    scopus 로고
    • Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis
    • Patel G., Karver C.E., Behera R., Guyett P.J., Sullenberger C., Edwards P., Roncal N.E., Mensa-Wilmot K., Pollastri M.P. Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis. J. Med. Chem. 2013, 56(10):3820-3832.
    • (2013) J. Med. Chem. , vol.56 , Issue.10 , pp. 3820-3832
    • Patel, G.1    Karver, C.E.2    Behera, R.3    Guyett, P.J.4    Sullenberger, C.5    Edwards, P.6    Roncal, N.E.7    Mensa-Wilmot, K.8    Pollastri, M.P.9
  • 157
    • 0026574444 scopus 로고
    • Eflornithine treatment of refractory Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome
    • Paulson Y.J., Gilman T.M., Heseltine P.N., Sharma O.P., Boylen C.T. Eflornithine treatment of refractory Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Chest 1992, 101(1):67-74.
    • (1992) Chest , vol.101 , Issue.1 , pp. 67-74
    • Paulson, Y.J.1    Gilman, T.M.2    Heseltine, P.N.3    Sharma, O.P.4    Boylen, C.T.5
  • 159
    • 0028366196 scopus 로고
    • The treatment of human African trypanosomiasis
    • Pepin J., Milord F. The treatment of human African trypanosomiasis. Adv. Parasitol. 1994, 33:1-47.
    • (1994) Adv. Parasitol. , vol.33 , pp. 1-47
    • Pepin, J.1    Milord, F.2
  • 160
    • 0023659828 scopus 로고
    • Difluoromethylornithine for arseno-resistant Trypanosoma brucei gambiense sleeping sickness
    • Pepin J., Milord F., Guern C., Schechter P.J. Difluoromethylornithine for arseno-resistant Trypanosoma brucei gambiense sleeping sickness. Lancet 1987, 2(8573):1431-1433.
    • (1987) Lancet , vol.2 , Issue.8573 , pp. 1431-1433
    • Pepin, J.1    Milord, F.2    Guern, C.3    Schechter, P.J.4
  • 161
    • 26044468809 scopus 로고    scopus 로고
    • Opportunities and challenges in antiparasitic drug discovery
    • Pink R., Hudson A., Mouries M.A., Bendig M. Opportunities and challenges in antiparasitic drug discovery. Nat. Rev. Drug Discov. 2005, 4(9):727-740.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , Issue.9 , pp. 727-740
    • Pink, R.1    Hudson, A.2    Mouries, M.A.3    Bendig, M.4
  • 163
    • 84867915028 scopus 로고    scopus 로고
    • In vitro antileishmanial drug susceptibility of clinical isolates from patients with Indian visceral leishmaniasis-status of newly introduced drugs
    • Prajapati V.K., Mehrotra S., Gautam S., Rai M., Sundar S. In vitro antileishmanial drug susceptibility of clinical isolates from patients with Indian visceral leishmaniasis-status of newly introduced drugs. Am. J. Trop. Med. Hyg. 2012, 87(4):655-657.
    • (2012) Am. J. Trop. Med. Hyg. , vol.87 , Issue.4 , pp. 655-657
    • Prajapati, V.K.1    Mehrotra, S.2    Gautam, S.3    Rai, M.4    Sundar, S.5
  • 164
    • 38449084743 scopus 로고    scopus 로고
    • Nifurtimox-eflornithine combination therapy for second-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Congo
    • Priotto G., Kasparian S., Ngouama D., Ghorashian S., Arnold U., Ghabri S., Karunakara U. Nifurtimox-eflornithine combination therapy for second-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Congo. Clin. Infect. Dis. 2007, 45(11):1435-1442.
    • (2007) Clin. Infect. Dis. , vol.45 , Issue.11 , pp. 1435-1442
    • Priotto, G.1    Kasparian, S.2    Ngouama, D.3    Ghorashian, S.4    Arnold, U.5    Ghabri, S.6    Karunakara, U.7
  • 167
    • 3442888590 scopus 로고    scopus 로고
    • Plasmodium falciparum carbonic anhydrase is a possible target for malaria chemotherapy
    • Reungprapavut S., Krungkrai S.R., Krungkrai J. Plasmodium falciparum carbonic anhydrase is a possible target for malaria chemotherapy. J. Enzyme Inhib. Med. Chem. 2004, 19(3):249-256.
    • (2004) J. Enzyme Inhib. Med. Chem. , vol.19 , Issue.3 , pp. 249-256
    • Reungprapavut, S.1    Krungkrai, S.R.2    Krungkrai, J.3
  • 171
    • 84859523382 scopus 로고    scopus 로고
    • Epidemiology of and diagnostic strategies for toxoplasmosis
    • Robert-Gangneux F., Darde M.L. Epidemiology of and diagnostic strategies for toxoplasmosis. Clin. Microbiol. Rev. 2012, 25(2):264-296.
    • (2012) Clin. Microbiol. Rev. , vol.25 , Issue.2 , pp. 264-296
    • Robert-Gangneux, F.1    Darde, M.L.2
  • 172
    • 84890861790 scopus 로고    scopus 로고
    • Synthesis and anti-plasmodium activity of benzimidazole analogues structurally related to astemizole
    • Roman G., Crandall I.E., Szarek W.A. Synthesis and anti-plasmodium activity of benzimidazole analogues structurally related to astemizole. ChemMedChem 2013.
    • (2013) ChemMedChem
    • Roman, G.1    Crandall, I.E.2    Szarek, W.A.3
  • 173
    • 33645862564 scopus 로고    scopus 로고
    • Congenital toxoplasmosis-prenatal aspects of Toxoplasma gondii infection
    • Rorman E., Zamir C.S., Rilkis I., Ben-David H. Congenital toxoplasmosis-prenatal aspects of Toxoplasma gondii infection. Reprod. Toxicol. 2006, 21(4):458-472.
    • (2006) Reprod. Toxicol. , vol.21 , Issue.4 , pp. 458-472
    • Rorman, E.1    Zamir, C.S.2    Rilkis, I.3    Ben-David, H.4
  • 178
    • 70449267916 scopus 로고
    • Treatment of amoebic hepatitis with emetine and chloroquine
    • Scaffidi V., Astuto R. Treatment of amoebic hepatitis with emetine and chloroquine. Panminerva Med. 1959, 1:162.
    • (1959) Panminerva Med. , vol.1 , pp. 162
    • Scaffidi, V.1    Astuto, R.2
  • 179
    • 77953024390 scopus 로고    scopus 로고
    • Efficacy of artemisinin in experimental visceral leishmaniasis
    • Sen R., Ganguly S., Saha P., Chatterjee M. Efficacy of artemisinin in experimental visceral leishmaniasis. Int. J. Antimicrob. Agents 2010, 36(1):43-49.
    • (2010) Int. J. Antimicrob. Agents , vol.36 , Issue.1 , pp. 43-49
    • Sen, R.1    Ganguly, S.2    Saha, P.3    Chatterjee, M.4
  • 180
    • 0035321503 scopus 로고    scopus 로고
    • Vaniqa-eflornithine 13.9% cream
    • 5
    • Shapiro J., Lui H. Vaniqa-eflornithine 13.9% cream. Skin Therapy Lett. 2001, 6(7):1-3, 5.
    • (2001) Skin Therapy Lett. , vol.6 , Issue.7 , pp. 1-3
    • Shapiro, J.1    Lui, H.2
  • 181
    • 79952459914 scopus 로고    scopus 로고
    • The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000-2009: the way forward
    • Simarro P.P., Diarra A., Ruiz Postigo J.A., Franco J.R., Jannin J.G. The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000-2009: the way forward. PLoS Negl. Trop. Dis. 2011, 5(2):e1007.
    • (2011) PLoS Negl. Trop. Dis. , vol.5 , Issue.2
    • Simarro, P.P.1    Diarra, A.2    Ruiz Postigo, J.A.3    Franco, J.R.4    Jannin, J.G.5
  • 182
    • 84861909705 scopus 로고    scopus 로고
    • Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis
    • Simarro P.P., Franco J., Diarra A., Postigo J.A., Jannin J. Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis. Parasitology 2012, 139(7):842-846.
    • (2012) Parasitology , vol.139 , Issue.7 , pp. 842-846
    • Simarro, P.P.1    Franco, J.2    Diarra, A.3    Postigo, J.A.4    Jannin, J.5
  • 184
    • 37849012349 scopus 로고    scopus 로고
    • The sulfonamide group as a structural alert: A distorted story?
    • Smith D.A., Jones R.M. The sulfonamide group as a structural alert: A distorted story?. Curr. Opin. Drug Discov. Devel. 2008, 11(1):72-79.
    • (2008) Curr. Opin. Drug Discov. Devel. , vol.11 , Issue.1 , pp. 72-79
    • Smith, D.A.1    Jones, R.M.2
  • 185
    • 0033638448 scopus 로고    scopus 로고
    • Phase II study of miltefosine 6% solution as topical treatment of skin metastases in breast cancer patients
    • Smorenburg C.H., Seynaeve C., Bontenbal M., Planting A.S., Sindermann H., Verweij J. Phase II study of miltefosine 6% solution as topical treatment of skin metastases in breast cancer patients. Anticancer Drugs 2000, 11(10):825-828.
    • (2000) Anticancer Drugs , vol.11 , Issue.10 , pp. 825-828
    • Smorenburg, C.H.1    Seynaeve, C.2    Bontenbal, M.3    Planting, A.S.4    Sindermann, H.5    Verweij, J.6
  • 187
    • 33645115547 scopus 로고    scopus 로고
    • Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial
    • Sotelo J., Briceno E., Lopez-Gonzalez M.A. Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 2006, 144(5):337-343.
    • (2006) Ann. Intern. Med. , vol.144 , Issue.5 , pp. 337-343
    • Sotelo, J.1    Briceno, E.2    Lopez-Gonzalez, M.A.3
  • 188
    • 77949441247 scopus 로고    scopus 로고
    • The development of drugs for treatment of sleeping sickness: a historical review
    • Steverding D. The development of drugs for treatment of sleeping sickness: a historical review. Parasit. Vectors 2010, 3(1):15.
    • (2010) Parasit. Vectors , vol.3 , Issue.1 , pp. 15
    • Steverding, D.1
  • 189
    • 0034780949 scopus 로고    scopus 로고
    • Drug resistance in Indian visceral leishmaniasis
    • Sundar S. Drug resistance in Indian visceral leishmaniasis. Trop. Med. Int. Health 2001, 6(11):849-854.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.11 , pp. 849-854
    • Sundar, S.1
  • 190
    • 78649980921 scopus 로고    scopus 로고
    • Liposomal amphotericin B and leishmaniasis: dose and response
    • Sundar S., Chakravarty J. Liposomal amphotericin B and leishmaniasis: dose and response. J. Global Infect. Dis. 2010, 2(2):159-166.
    • (2010) J. Global Infect. Dis. , vol.2 , Issue.2 , pp. 159-166
    • Sundar, S.1    Chakravarty, J.2
  • 191
    • 84871558204 scopus 로고    scopus 로고
    • Leishmaniasis: an update of current pharmacotherapy
    • Sundar S., Chakravarty J. Leishmaniasis: an update of current pharmacotherapy. Expert Opin. Pharmacother. 2013, 14(1):53-63.
    • (2013) Expert Opin. Pharmacother. , vol.14 , Issue.1 , pp. 53-63
    • Sundar, S.1    Chakravarty, J.2
  • 192
    • 0034451615 scopus 로고    scopus 로고
    • Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic
    • Sundar S., More D.K., Singh M.K., Singh V.P., Sharma S., Makharia A., Kumar P.C., Murray H.W. Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic. Clin. Infect. Dis. 2000, 31(4):1104-1107.
    • (2000) Clin. Infect. Dis. , vol.31 , Issue.4 , pp. 1104-1107
    • Sundar, S.1    More, D.K.2    Singh, M.K.3    Singh, V.P.4    Sharma, S.5    Makharia, A.6    Kumar, P.C.7    Murray, H.W.8
  • 193
    • 42149158230 scopus 로고    scopus 로고
    • Carbonic anhydrases as drug targets
    • Supuran C.T. Carbonic anhydrases as drug targets. Curr. Pharm. Des. 2008, 14(7):601-602.
    • (2008) Curr. Pharm. Des. , vol.14 , Issue.7 , pp. 601-602
    • Supuran, C.T.1
  • 194
    • 38849143765 scopus 로고    scopus 로고
    • Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
    • Supuran C.T. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat. Rev. Drug Discov. 2008, 7(2):168-181.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , Issue.2 , pp. 168-181
    • Supuran, C.T.1
  • 195
    • 77954218410 scopus 로고    scopus 로고
    • Carbonic anhydrase inhibitors
    • Supuran C.T. Carbonic anhydrase inhibitors. Bioorg. Med. Chem. Lett. 2010, 20(12):3467-3474.
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , Issue.12 , pp. 3467-3474
    • Supuran, C.T.1
  • 197
    • 84884993499 scopus 로고    scopus 로고
    • Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis
    • Syrjanen L., Vermelho A.B., de Almeida Rodrigues I., Corte-Real S., Salonen T., Pan P., Vullo D., Parkkila S., Capasso C., Supuran C.T. Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis. J. Med. Chem. 2013, 56(18):7372-7381.
    • (2013) J. Med. Chem. , vol.56 , Issue.18 , pp. 7372-7381
    • Syrjanen, L.1    Vermelho, A.B.2    de Almeida Rodrigues, I.3    Corte-Real, S.4    Salonen, T.5    Pan, P.6    Vullo, D.7    Parkkila, S.8    Capasso, C.9    Supuran, C.T.10
  • 198
    • 79957998176 scopus 로고    scopus 로고
    • Doxycycline for malaria chemoprophylaxis and treatment: report from the CDC expert meeting on malaria chemoprophylaxis
    • Centers for Disease C. and Prevention
    • Tan K.R., Magill A.J., Parise M.E., Arguin P.M., Centers for Disease C. and Prevention Doxycycline for malaria chemoprophylaxis and treatment: report from the CDC expert meeting on malaria chemoprophylaxis. Am. J. Trop. Med. Hyg. 2011, 84(4):517-531.
    • (2011) Am. J. Trop. Med. Hyg. , vol.84 , Issue.4 , pp. 517-531
    • Tan, K.R.1    Magill, A.J.2    Parise, M.E.3    Arguin, P.M.4
  • 199
    • 24644446896 scopus 로고    scopus 로고
    • Open label extension studies: research or marketing?
    • Taylor G.J., Wainwright P. Open label extension studies: research or marketing?. BMJ 2005, 331(7516):572-574.
    • (2005) BMJ , vol.331 , Issue.7516 , pp. 572-574
    • Taylor, G.J.1    Wainwright, P.2
  • 200
    • 0032804471 scopus 로고    scopus 로고
    • Amphotericin B deoxycholate treatment of visceral leishmaniasis with newer modes of administration and precautions: a study of 938 cases
    • Thakur C.P., Singh R.K., Hassan S.M., Kumar R., Narain S., Kumar A. Amphotericin B deoxycholate treatment of visceral leishmaniasis with newer modes of administration and precautions: a study of 938 cases. Trans. R. Soc. Trop. Med. Hyg. 1999, 93(3):319-323.
    • (1999) Trans. R. Soc. Trop. Med. Hyg. , vol.93 , Issue.3 , pp. 319-323
    • Thakur, C.P.1    Singh, R.K.2    Hassan, S.M.3    Kumar, R.4    Narain, S.5    Kumar, A.6
  • 201
    • 84879575765 scopus 로고    scopus 로고
    • The global burden of congenital toxoplasmosis: a systematic review
    • Torgerson P.R., Mastroiacovo P. The global burden of congenital toxoplasmosis: a systematic review. Bull. World Health Organ. 2013, 91(7):501-508.
    • (2013) Bull. World Health Organ. , vol.91 , Issue.7 , pp. 501-508
    • Torgerson, P.R.1    Mastroiacovo, P.2
  • 202
    • 34548032814 scopus 로고    scopus 로고
    • Antibodies to Toxoplasma gondii in patients with schizophrenia: a meta-analysis
    • Torrey E.F., Bartko J.J., Lun Z.R., Yolken R.H. Antibodies to Toxoplasma gondii in patients with schizophrenia: a meta-analysis. Schizophr. Bull. 2007, 33(3):729-736.
    • (2007) Schizophr. Bull. , vol.33 , Issue.3 , pp. 729-736
    • Torrey, E.F.1    Bartko, J.J.2    Lun, Z.R.3    Yolken, R.H.4
  • 203
    • 0142227145 scopus 로고    scopus 로고
    • Specific chemotherapy of Chagas disease: controversies and advances
    • Urbina J.A., Docampo R. Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasitol. 2003, 19(11):495-501.
    • (2003) Trends Parasitol. , vol.19 , Issue.11 , pp. 495-501
    • Urbina, J.A.1    Docampo, R.2
  • 204
    • 0026793457 scopus 로고
    • Advances in sleeping sickness therapy
    • Van Nieuwenhove S. Advances in sleeping sickness therapy. Ann. Soc. Belg. Med. Trop. 1992, 72(Suppl. 1):39-51.
    • (1992) Ann. Soc. Belg. Med. Trop. , vol.72 , Issue.SUPPL. 1 , pp. 39-51
    • Van Nieuwenhove, S.1
  • 208
    • 0015389380 scopus 로고
    • Experience with nifurtimox in chronic Chagas' infection. Preliminary report
    • Wegner D.H., Rohwedder R.W. Experience with nifurtimox in chronic Chagas' infection. Preliminary report. Arzneimittelforschung 1972, 22(9):1635-1641.
    • (1972) Arzneimittelforschung , vol.22 , Issue.9 , pp. 1635-1641
    • Wegner, D.H.1    Rohwedder, R.W.2
  • 210
    • 77956286255 scopus 로고    scopus 로고
    • Microbiology. Is the tide turning for new malaria medicines?
    • Wells T.N. Microbiology. Is the tide turning for new malaria medicines?. Science 2010, 329(5996):1153-1154.
    • (2010) Science , vol.329 , Issue.5996 , pp. 1153-1154
    • Wells, T.N.1
  • 211
    • 2942590820 scopus 로고    scopus 로고
    • Nitazoxanide: a new broad spectrum antiparasitic agent
    • White C.A. Nitazoxanide: a new broad spectrum antiparasitic agent. Expert Rev. Anti Infect. Ther. 2004, 2(1):43-49.
    • (2004) Expert Rev. Anti Infect. Ther. , vol.2 , Issue.1 , pp. 43-49
    • White, C.A.1
  • 212
    • 0009516038 scopus 로고
    • Treatment of acute malaria with pyrimethamine
    • Wilson T., Edeson J.F. Treatment of acute malaria with pyrimethamine. Br. Med. J. 1953, 1(4804):253-255.
    • (1953) Br. Med. J. , vol.1 , Issue.4804 , pp. 253-255
    • Wilson, T.1    Edeson, J.F.2
  • 213
    • 0034775612 scopus 로고    scopus 로고
    • Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria
    • Winstanley P. Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria. Trop. Med. Int. Health 2001, 6(11):952-954.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.11 , pp. 952-954
    • Winstanley, P.1
  • 216
    • 84897998551 scopus 로고    scopus 로고
    • World Health Organization, 2008. The global burden of disease: update.
    • World Health Organization, 2008. The global burden of disease: 2004 update.
  • 217
    • 84897976694 scopus 로고    scopus 로고
    • World Health Organization, Global report on antimalarial drug efficacy and drug resistance: 2000-2010.
    • World Health Organization 2010, Global report on antimalarial drug efficacy and drug resistance: 2000-2010.
    • (2010)
  • 218
    • 84898003209 scopus 로고    scopus 로고
    • World Health Organization, Chagas Disease: control and elimination. World Health Assembly Report.
    • World Health Organization, 2010a. Chagas Disease: control and elimination. World Health Assembly Report.
    • (2010)
  • 219
    • 84897981786 scopus 로고    scopus 로고
    • World Health Organization, Working to overcome the global impact of neglected tropical diseases. First WHO report on neglected tropical diseases.
    • World Health Organization, 2010b. Working to overcome the global impact of neglected tropical diseases. First WHO report on neglected tropical diseases.
    • (2010)
  • 220
    • 84897989957 scopus 로고    scopus 로고
    • World Health Organization, Global Health Observatory Map Gallery. Retrieved 15th November, from
    • World Health Organization, Global Health Observatory Map Gallery. Retrieved 15th November, 2013, from http://gamapserver.who.int/mapLibrary/.
    • (2013)
  • 221
    • 84897977671 scopus 로고    scopus 로고
    • World Health Organization, World Malaria Report 2013.
    • World Health Organization, 2013. World Malaria Report 2013.
    • (2013)
  • 222
    • 26844510687 scopus 로고    scopus 로고
    • Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins
    • Xiao S.H. Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins. Acta Trop. 2005, 96(2-3):153-167.
    • (2005) Acta Trop. , vol.96 , Issue.2-3 , pp. 153-167
    • Xiao, S.H.1
  • 224
    • 0025776247 scopus 로고
    • Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature
    • Zic J.A., Horowitz D.H., Arzubiaga C., King L.E. Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature. Arch. Dermatol. 1991, 127(7):1034-1040.
    • (1991) Arch. Dermatol. , vol.127 , Issue.7 , pp. 1034-1040
    • Zic, J.A.1    Horowitz, D.H.2    Arzubiaga, C.3    King, L.E.4


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