Increased incidence of traffic accidents in Toxoplasma-infected military drivers and protective effect RhD molecule revealed by a large-scale prospective cohort study

BMC Infectious Diseases

Volumn 9, Issue , 2009, Pages

  Klose, Jiří ^b   Novotná, Martina ^a   Berenreitterová, Miroslava ^a   Havlíček, Jan ^a   Flegr, Jaroslav ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b CENTRAL MILITARY HOSPITAL   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

RHESUS D ANTIBODY; PROTOZOON ANTIBODY; RHO(D) ANTIGEN;

ACCIDENT PREVENTION; ADULT; ANTIBODY TITER; ARTICLE; ATTRIBUTABLE RISK; CONTROLLED STUDY; CZECH REPUBLIC; DRIVER; HIGH RISK POPULATION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PHENOTYPE; PROSPECTIVE STUDY; PSYCHOLOGIC TEST; SOLDIER; TOXOPLASMOSIS; TRAFFIC ACCIDENT; BLOOD; BLOOD GROUP RHESUS SYSTEM; GENETIC POLYMORPHISM; GENETICS; RISK FACTOR; STATISTICAL MODEL;

ACCIDENTS, TRAFFIC; ANTIBODIES, PROTOZOAN; HUMANS; INCIDENCE; LOGISTIC MODELS; MALE; MILITARY PERSONNEL; PHENOTYPE; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; RH-HR BLOOD-GROUP SYSTEM; RISK FACTORS; TOXOPLASMOSIS; YOUNG ADULT;

EID: 67649687838     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-9-72     Document Type: Article

References (24)

1. Tenter AM Heckeroth AR Weiss LM Toxoplasma gondii: From animals to humans Int J Parasitol 2000, 30:1217-1258. 10.1016/S0020-7519(00)00124-7 11113252
2. Remington JS Krahenbuhl JL Immunology of Toxoplasma gondii Immunology of human infection, Part II New York: Plenum Publishing Corporation Nahmias AJ, O'Reilly J 1982 327 371
3. Jones JL Kruszon-Moran D Wilson M McQuillan G Navin T Mcauley JB Toxoplasma gondii infection in the United States: Seroprevalence and risk factors Am J Epidemiol 2001, 154:357-365. 10.1093/aje/154.4.357 11495859
4. Markell EK John DT Krotoski WA Markell and Voge's Medical parasitology. Philadelphia: W.B. Saunders Company 8 1999
5. Roberts LS Janovy J Jr Roberts' Foundations of parasitology. Boston: McGraw-Hill Companies, Inc Gerald S Schmidt, Larry S 6 2000
6. Havlíček J Gašová Z Smith AP Zvára K Flegr J Decrease of psychomotor performance in subjects with latent 'asymptomatic' toxoplasmosis Parasitology 2001, 122:515-520. 11393824
7. Flegr J Havlíček J Kodym P Malý M Smahel Z Increased risk of traffic accidents in subjects with latent toxoplasmosis: A retrospective case-control study BMC Infect Dis 2002:2. art-11 117239 12095427
8. Yereli K Balcioglu IC Ozbilgin A -Is Toxoplasma gondii a potential risk for traffic accidents in Turkey? Forensic Sci Int 2006, 163:34-37. 10.1016/j.forsciint.2005.11.002 16332418
9. Novotná M Havlíček J Smith AP Kolbeková P Skallová A Klose J Gašová Z Písačka M Sechovská M Flegr J Toxoplasma and reaction time: Role of toxoplasmosis in the origin, preservation and geographical distribution of Rh blood group polymorphism Parasitology 2008, 135:1253-1261. 10.1017/ S003118200800485X 18752708
10. Flegr J Novotná M Lindová J Havlíček J Neurophysiological effect of Rh factor. Protective role of the RhD molecule against Toxoplasma-induced impairment of reaction times in women Neuro Endocrinol Lett 2008, 29:475-481. 18766148
11. 2: Evidence that Rh (rhesus) proteins are CO2 channels Transf Clin Biol 2006, 13:103-110. 10.1016/j.tracli.2006.03.001
12. Biver S Scohy S Szpirer J Szpirer C Andre B Marini AM Physiological role of the putative ammonium transporter RhCG in the mouse Transf Clin Biol 2006, 13:167-168. 10.1016/j.tracli.2006.03.003
13. Flegr J Hrdý I Influence of chronic toxoplasmosis on some human personality factors Folia Parasitol 1994, 41:122-126. 7927062
14. Daniels G Human blood groups Oxford: Blackwell Publishers 2002
15. Kodym P Malý M Svandová E Lekatková H Badoutová M Vlková J Beneš C Zástěra M Toxoplasma in the Czech Republic 1923-1999: First case to widespread outbreak Int J Parasitol 2000, 30:11-18
16. Pokorny J Fruhbauer Z Polednakova S Sykora J Zastera M Fialova D Stanoveni antitoxoplasmickych protilatek IgG netodou ELISA (Assessment of antitoxoplasmatic IgG antibodies with the ELISA method) Cs Epidem 1989, 38:355-361
17. Kodym P Machala L Roháčová H Širocká B Malý M Evaluation of a commercial IgE ELISA in comparison with IgA and IgM ELISAs, IgG avidity assay and complement fixation for the diagnosis of acute toxoplasmosis Clin Microbiol Infect 2007, 13:40-47. 10.1111/j.1469-0691.2006.01564.x 17184286
18. Montoya JG Liesenfeld O Toxoplasmosis Lancet 2004, 363:1965-1975. 10.1016/S0140-6736(04)16412-X 15194258
19. Petridou E Moustaki M Human factors in the causation of road traffic crashes Europ J Epidemiol 2000, 16:819-826. 10.1023/A:1007649804201
20. Hrdá S Votýpka J Kodym P Flegr J Transient nature of Toxoplasma gondii-induced behavioral changes in mice J Parasitol 2000, 86:657-663. 10958436
21. Flegr J Hrušková M Hodný Z Novotná M Hanušová J Body height, body mass index, waist-hip ratio, fluctuating asymmetry and second to fourth digit ratio in subjects with latent toxoplasmosis Parasitology 2005, 130:621-628. 10.1017/ S0031182005007316 15977898
22. Hodková H Kolbeková P Skallová A Lindová J Flegr J Higher perceived dominance in Toxoplasma infected men - the new evidence for role of increased level of testosterone in toxoplasmosis-associated changes in human behavior Neuro Endocrinol Lett 2007, 28(2):110-114. 17435678
23. Flegr J Lindová J Kodym P Sex-dependent toxoplasmosis-associated differences in testosterone concentration in humans Parasitology 2008, 135:427-431. 10.1017/S0031182007004064 18205984
24. Archer J Testosterone and human aggression: An evaluation of the challenge hypothesis Neurosci Biobehav Rev 2006, 30:319-345. 10.1016/ j.neubiorev.2004.12.007 16483890