Bioaccessibility of T-2 and HT-2 toxins in mycotoxin contaminated bread models submitted to in vitro human digestion

Innovative Food Science and Emerging Technologies

Volumn 22, Issue , 2014, Pages 248-256

  De Angelis, Elisabetta ^a   Monaci, Linda ^a   Mackie, Alan ^b   Salt, Louise ^b   Visconti, Angelo ^a  

^a INSTITUTE OF SCIENCES OF FOOD PRODUCTION   (Italy)

^b INSTITUTE OF FOOD RESEARCH   (United Kingdom)

Author keywords

Bioaccessibility; Bread; Gastro duodenal tract; HT 2; In vitro digestion; Mass spectrometry; Mycotoxin stability; T 2

Indexed keywords

BIOCHEMISTRY; CEREAL PRODUCTS; CONTAMINATION; FOOD PROCESSING; MASS SPECTROMETRY; METABOLITES; NUTRITION; TOXICITY;

BIOACCESSIBILITY; BREAD; GASTRO-DUODENAL TRACT; HT-2; IN-VITRO DIGESTIONS; T-2;

FOOD SAFETY;

FUSARIUM; TRITICUM AESTIVUM;

EID: 84897070788     PISSN: 14668564     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ifset.2013.11.011     Document Type: Article

References (44)

1. G. Avantaggiato, R. Havenaar, and A. Visconti Assessing the zearalenone-binding activity of adsorbent materials during passage through a dynamic in vitro gastrointestinal model Food and Chemical Toxicology 41 2003 1283 1290
2. G. Avantaggiato, R. Havenaar, and A. Visconti Evaluation of the intestinal absorption of deoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy of activated carbon and other adsorbent materials Food and Chemical Toxicology 42 2004 817 824
3. G. Avantaggiato, R. Havenaar, and A. Visconti Assessment of the multi-mycotoxin-binding efficacy of a carbon/aluminosilicate-based product in an in vitro gastrointestinal model Journal of Agricultural and Food Chemistry 55 2007 4810 4819
4. F. Berthiller, C. Crews, C. Dall'Asta, S. De Saeger, G. Haesaert, and P. Karlovsky et al. Masked mycotoxins: A review Molecular Nutrition & Food Research 57 2013 165 186
5. F. Berthiller, R. Krska, K.J. Domig, W. Kneifel, N. Juge, and R. Schuhmacher et al. Hydrolytic fate of deoxynivalenol-3-glucoside during digestion Toxicology Letters 206 2011 264 267
6. E.F.A. Brandon, A.G. Oomen, C.J.M. Rompelberg, C.H.M. Versantvoort, J.G.M. van Engelen, and A.J.A.M. Sips Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment Regulatory Toxicology and Pharmacology 44 2006 161 171
7. G. Cano-Sancho, F.M. Valle-Algarra, M. Jiménez, P. Burdaspal, T.M. Legarda, and A.J. Ramos et al. Presence of trichothecenes and co-occurrence in cereal-based food from Catalonia (Spain) Food Control 22 2011 490 495
8. Commission Recommendation of 27 March 2013 on the presence of T-2 and HT-2 toxin in cereals and cereal products. Official Journal of the European Union, L 91/12.
9. Commission Regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuff. Official Journal of the European Union, L 364/5.
10. Commission Regulation (EC) No 1126/2007 amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products. Official Journal of the European Union, L 255/14.
11. A. Dall'Erta, M. Cirlini, M. Dall'Asta, D. Del Rio, G. Galaverna, and C. Dall'Asta Masked mycotoxins are efficiently hydrolized by human colonic microbiota releasing aglycones Chemical Research in Toxicology 26 2013 305 312
12. E. De Angelis, L. Monaci, M. Pascale, and A. Visconti Fate of deoxynivalenol, T-2 and HT-2 toxins and their glucoside conjugates from flour to bread: an investigation by HPLC-high resolution-mass spectrometry Food Additives & Contaminants: Part A 30 2 2013 345 355
13. M. De Boevre, J.D. Di Mavungu, S. Landschoot, K. Audenaert, M. Eeckhout, and P. Maene et al. Natural occurrence of mycotoxins and their masked forms in food and feed products World Mycotoxin Journal 5 2012 207 219
14. A. Desmarchelier, and W. Seefelder Survey of deoxynivalenol and deoxynivalenol-3-glucoside in cereal-based products by liquid chromatography electrospray ionization tandem mass spectrometry World Mycotoxin Journal 4 2011 29 35
15. EFSA Panel on Contaminants in the Food Chain Scientific opinion on the risks for animal and public health related to the presence of T-2 and HT-2 toxin in food and feed EFSA Journal 9 12 2011 2481
16. C.A. González-Arias, S. Marín, V. Sanchis, and A.J. Ramos Mycotoxin bioaccessibility/absorption using in vitro digestion model: A review World Mycotoxin Journal 6 2013 167 184
17. L. González-Osnaya, C. Cortés, J.M. Soriano, J.C. Moltó, and J. Mañes Occurrence of deoxynivalenol and T-2 toxin in bread and pasta commercialised in Spain Food Chemistry 124 2011 156 161
18. C.M. Hazel, and S. Patel Influence of processing on trichothecenes levels Toxicology Letters 153 2004 51 59
19. J. He, T. Zhou, J.C. Young, G.J. Boland, and P.M. Scott Chemical and biological transformations for detoxification of trichothecene mycotoxins in human and animal food chains: A review Trends in Food Science & Technology 21 2010 67 76
20. S.J. Hur, B.O. Lim, E.A. Decker, and D.J. McClements In vitro human digestion models for food applications Food Chemistry 125 2011 1 12
21. B. Kabak, E.F.A. Brandon, I. Var, M. Blokland, and A.J.A.M. Sips Effects of probiotic bacteria on the bioaccessibility of aflatoxin B1 and ochratoxin A using an in vitro digestion model under fed conditions Journal of Environmental Science and Health. Part. B 44 2009 472 480
22. M. Kostelanska, Z. Dzuman, A. Malachova, I. Capouchova, E. Prokinova, and A. Skerikova et al. Effects of milling and baking technologies on levels of deoxynivalenol and its masked form deoxynivalenol-3-glucoside Journal of Agricultural and Food Chemistry 59 2011 9303 9312
23. M. Kostelanska, J. Hajslova, M. Zachariasova, A. Malachova, K. Kalachova, and J. Poustka et al. Occurrence of deoxynivalenol and its major conjugate, deoxynivalenol-3-glucoside, in beer and some brewing intermediates Journal of Agricultural and Food Chemistry 57 2009 3187 3194
24. M. Kostelanska, M. Zachariasova, O. Lacina, M. Fenclova, A. Kollos, and J. Hajslova The study of deoxynivalenol and its masked metabolites fate during the brewing process realised by UPLC-TOFMS method Food Chemistry 126 2011 1870 1876
25. K. Lancova, J. Hajslova, J. Poustka, A. Krplova, M. Zachariasova, and P. Dostalek et al. Transfer of Fusarium mycotoxins and "masked" deoxynivalenol (deoxynivalenol-3-glucoside) from field barley through malt to beer Food Additives & Contaminants 25 2008 732 744
26. Y. Li, Z. Wang, R.C. Beier, J. Shen, D. De Smet, and S. De Saeger et al. T-2 toxin, a trichothecene mycotoxin: Review of toxicity, metabolism, and analytical methods Journal of Agricultural and Food Chemistry 59 2011 3441 3453
27. A. Mackie, and A. Macierzanka Colloidal aspects of protein digestion Current Opinion in Colloid & Interface Science 15 2010 102 108
28. G. Mandalari, A.M. Mackie, N.M. Rigby, M.S. Wickham, and E.N. Mills Physiological phosphatidylcholine protects bovine beta-lactoglobulin from simulated gastrointestinal proteolysis Molecular Nutrition & Food Research 53 2009 S131 S139
29. S.P. McCormick, N.P.J. Price, and C.P. Kurtzman Glucosylation and other biotransformation of T-2 toxin by yeast of the Trichomonascus Clade Applied and Environmental Microbiology 78 2012 8694 8702
30. L. Monaci, E. De Angelis, and A. Visconti Determination of deoxynivalenol, T-2 and HT-2 toxins in a bread model food by liquid chromatography-high resolution-Orbitrap-Mass Spectrometry equipped with a high-energy collision dissociation cell Journal of Chromatography A 1218 2011 8646 8654
31. F.J. Moreno, A.R. Mackie, and E.N.C. Mills Phospholipid interactions protect the milk allergen alpha-lactalbumin from proteolysis during in vitro digestion Journal of Agricultural and Food Chemistry 53 2005 9810 9816
32. M. Pascale, M. Haidukowski, V.M.T. Lattanzio, M. Silvestri, R. Ranieri, and A. Visconti Distribution of T-2 and HT-2 toxins in milling fractions of durum wheat Journal of Food Protection 74 2011 1700 1707
33. H. Pettersson Toxicity and risks with T-2 and HT-2 toxins in cereals Plant Breeding and Seed Science 64 2011 65 74
34. A. Poapolathep, S. Poapolathep, N. Klangkaew, Y. Sugita-Konishi, and S. Kumagai Detection of deoxynivalenol contamination in wheat products in Thailand Journal of Food Protection 71 2008 1931 1933
35. A. Raiola, G. Meca, J. Manes, and A. Ritieni Bioaccessibility of deoxynivalenol and its natural co-occurrence with ochratoxin A and aflatoxin B1 in Italian commercial pasta Food and Chemical Toxicology 50 2012 280 287
36. R.C. Schothorst, and H.P. van Egmond Report from SCOOP task 3.2.10 "collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU member states" subtask: trichothecenes Toxicology Letters 153 2004 133 143
37. D.L. Sudakin Trichothecenes in the environment: relevance to human health Toxicology Letters 143 2003 97 107
38. H.J. van der Fels-Klerx Scientific/technical report submitted to EFSA Occurrence data of trichothecene mycotoxins T-2 toxin and HT-2 toxin in food and feed. EFSA-Q-2010-00949 2010 (Available at http://www.efsa.europa.eu/en/scdocs/ doc/66e.pdf.)
39. O. Vendl, C. Crews, S. MacDonald, R. Krska, and F. Berthiller Occurrence of free and conjugated Fusarium mycotoxins in cereal-based food Food Additives & Contaminants: Part A 27 2010 1148 1152
40. C. Versantvoort, A. Oomen, E. Van de Kamp, C. Rompelberg, and A. Sips Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food Food and Chemical Toxicology 43 2005 31 40
41. C.H.M. Versantvoort, E. van de Kamp, and C.J.M. Rompelberg Development and applicability of an in vitro digestion model in assessing the bioaccessibility of contaminants from food 2004 (Available at http://rivm.openrepository.com/rivm/bitstream/10029/8885/1/320102002.pdf.)
42. A. Visconti, E.M. Haidukowski, M. Pascale, and M. Silvestri Reduction of deoxynivalenol during durum wheat processing and spaghetti cooking Toxicology Letters 153 2004 181 189
43. A. Visconti, F. Minervini, G. Lucivero, and V. Gambatesa Cytotoxic and immunotoxic effects of Fusarium mycotoxins using a rapid colorimetric bioassay Mycopathologia 113 1991 181 186
44. T. Zhou, J. He, and J. Gong Microbial transformation of trichothecene mycotoxins World Mycotoxin Journal 1 2008 23 30