메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Role of microRNAs in islet beta-cell compensation and failure during diabetes

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; MICRORNA;

EID: 84897003161     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2014/618652     Document Type: Review
Times cited : (53)

References (114)
  • 1
    • 33745863033 scopus 로고    scopus 로고
    • Islet β cell failure in type 2 diabetes
    • DOI 10.1172/JCI29103
    • Prentki M., Nolan C. J., Islet β cell failure in type 2 diabetes. The Journal of Clinical Investigation 2006 116 7 1802 1812 2-s2.0-33745863033 10.1172/JCI29103 (Pubitemid 44033300)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 2
    • 9444242665 scopus 로고    scopus 로고
    • Five of stages of evolving β-cell dysfunction during progression to diabetes
    • DOI 10.2337/diabetes.53.suppl-3.S16
    • Weir G. C., Bonner-Weir S., Five of stages of evolving β -cell dysfunction during progression to diabetes. Diabetes 2004 53 supplement 3 S16 S21 2-s2.0-9444242665 10.2337/diabetes.53.suppl-3.S16 (Pubitemid 39564517)
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Weir, G.C.1    Bonner-Weir, S.2
  • 3
    • 0037219411 scopus 로고    scopus 로고
    • β-Cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
    • DOI 10.2337/diabetes.52.1.102
    • Butler A. E., Janson J., Bonner-Weir S., Ritzel R., Rizza R. A., Butler P. C., β -cell deficit and increased β -cell apoptosis in humans with type 2 diabetes. Diabetes 2003 52 1 102 110 2-s2.0-0037219411 10.2337/diabetes.52.1.102 (Pubitemid 36042113)
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 4
    • 84862516777 scopus 로고    scopus 로고
    • Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans
    • 2-s2.0-84856104087 10.1007/s00125-012-2466-8
    • Meier J. J., Breuer T. G. K., Bonadonna R. C., Tannapfel A., Uhl W., Schmidt W. E., Schrader H., Menge B. A., Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans. Diabetologia 2012 55 5 1346 1354 2-s2.0-84856104087 10.1007/s00125-012-2466-8
    • (2012) Diabetologia , vol.55 , Issue.5 , pp. 1346-1354
    • Meier, J.J.1    Breuer, T.G.K.2    Bonadonna, R.C.3    Tannapfel, A.4    Uhl, W.5    Schmidt, W.E.6    Schrader, H.7    Menge, B.A.8
  • 5
    • 41849097354 scopus 로고    scopus 로고
    • Beta cell mass in diabetes: A realistic therapeutic target?
    • 2-s2.0-41849097354 10.1007/s00125-008-0936-9
    • Meier J. J., Beta cell mass in diabetes: a realistic therapeutic target? Diabetologia 2008 51 5 703 713 2-s2.0-41849097354 10.1007/s00125-008-0936-9
    • (2008) Diabetologia , vol.51 , Issue.5 , pp. 703-713
    • Meier, J.J.1
  • 6
    • 23644457358 scopus 로고    scopus 로고
    • β-Cell function in morbidly obese subjects during free living: Long-term effects of weight loss
    • DOI 10.2337/diabetes.54.8.2382
    • Camastra S., Manco M., Mari A., Baldi S., Gastaldelli A., Greco A. V., Mingrone G., Ferrannini E., β -cell function in morbidly obese subjects during free living: long-term effects of weight loss. Diabetes 2005 54 8 2382 2389 2-s2.0-23644457358 10.2337/diabetes.54.8.2382 (Pubitemid 41134266)
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2382-2389
    • Camastra, S.1    Manco, M.2    Mari, A.3    Baldi, S.4    Gastaldelli, A.5    Greco, A.V.6    Mingrone, G.7    Ferrannini, E.8
  • 7
    • 33644747390 scopus 로고    scopus 로고
    • Mechanisms of β-cell death in type 2 diabetes
    • DOI 10.2337/diabetes.54.suppl-2.S108
    • Donath M. Y., Ehses J. A., Maedler K., Schumann D. M., Ellingsgaard H., Eppler E., Reinecke M., Mechanisms of β -cell death in type 2 diabetes. Diabetes 2005 54 supplement 2 S108 S113 2-s2.0-33644747390 10.2337/diabetes.54. suppl-2.S108 (Pubitemid 43343338)
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Donath, M.Y.1    Ehses, J.A.2    Maedler, K.3    Schumann, D.M.4    Ellingsgaard, H.5    Eppler, E.6    Reinecke, M.7
  • 8
    • 53549093011 scopus 로고    scopus 로고
    • Pancreatic β -cell mass in European subjects with type 2 diabetes
    • supplement 4 2-s2.0-53549093011 10.1111/j.1463-1326.2008.00969.x
    • Rahier J., Guiot Y., Goebbels R. M., Sempoux C., Henquin J. C., Pancreatic β -cell mass in European subjects with type 2 diabetes. Diabetes, Obesity & Metabolism 2008 10 supplement 4 32 42 2-s2.0-53549093011 10.1111/j.1463-1326.2008.00969.x
    • (2008) Diabetes, Obesity & Metabolism , vol.10 , pp. 32-42
    • Rahier, J.1    Guiot, Y.2    Goebbels, R.M.3    Sempoux, C.4    Henquin, J.C.5
  • 11
    • 0035143062 scopus 로고    scopus 로고
    • Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets. Effects of the ob gene and compensatory growth of the implantation organ
    • Tyrberg B., Ustinov J., Otonkoski T., Andersson A., Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets: effects of the ob gene and compensatory growth of the implantation organ. Diabetes 2001 50 2 301 307 2-s2.0-0035143062 (Pubitemid 32127286)
    • (2001) Diabetes , vol.50 , Issue.2 , pp. 301-307
    • Tyrberg, B.1    Ustinov, J.2    Otonkoski, T.3    Andersson, A.4
  • 12
    • 20444363538 scopus 로고    scopus 로고
    • Beta-cells in type 2 diabetes: A loss of function and mass
    • supplement 3 2-s2.0-20444363538
    • Maedler K., Donath M. Y., Beta-cells in type 2 diabetes: a loss of function and mass. Hormone Research 2004 62 supplement 3 67 73 2-s2.0-20444363538
    • (2004) Hormone Research , vol.62 , pp. 67-73
    • Maedler, K.1    Donath, M.Y.2
  • 13
    • 33750577223 scopus 로고    scopus 로고
    • Aging correlates with decreased β-cell proliferative capacity and enhanced sensitivity to apoptosis: A potential role for fas and pancreatic duodenal homeobox-1
    • DOI 10.2337/db05-1586
    • Maedler K., Schumann D. M., Schulthess F., Oberholzer J., Bosco D., Berney T., Donath M. Y., Aging correlates with decreased β -cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for fas and pancreatic duodenal homeobox-1. Diabetes 2006 55 9 2455 2462 2-s2.0-33750577223 10.2337/db05-1586 (Pubitemid 44871145)
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2455-2462
    • Maedler, K.1    Schumann, D.M.2    Schulthess, F.3    Oberholzer, J.4    Bosco, D.5    Berney, T.6    Donath, M.Y.7
  • 14
    • 0027253061 scopus 로고
    • Long-term complications of diabetes mellitus
    • DOI 10.1056/NEJM199306103282306
    • Nathan D. M., Long-term complications of diabetes mellitus. The New England Journal of Medicine 1993 328 23 1676 1685 2-s2.0-0027253061 10.1056/NEJM199306103282306 (Pubitemid 23157351)
    • (1993) New England Journal of Medicine , vol.328 , Issue.23 , pp. 1676-1685
    • Nathan, D.M.1
  • 15
    • 9444291835 scopus 로고    scopus 로고
    • Islet graft assessment in the Edmonton Protocol: Implications for predicting long-term clinical outcome
    • DOI 10.2337/diabetes.53.12.3107
    • Street C. N., Lakey J. R. T., Shapiro A. M. J., Imes S., Rajotte R. V., Ryan E. A., Lyon J. G., Kin T., Avila J., Tsujimura T., Korbutt G. S., Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome. Diabetes 2004 53 12 3107 3114 2-s2.0-9444291835 10.2337/diabetes.53.12.3107 (Pubitemid 39564485)
    • (2004) Diabetes , vol.53 , Issue.12 , pp. 3107-3114
    • Street, C.N.1    Lakey, J.R.T.2    Shapiro, A.M.J.3    Imes, S.4    Rajotte, R.V.5    Ryan, E.A.6    Lyon, J.G.7    Kin, T.8    Avila, J.9    Tsujimura, T.10    Korbutt, G.S.11
  • 16
    • 2342466734 scopus 로고    scopus 로고
    • Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
    • DOI 10.2337/diacare.27.5.1047
    • Wild S., Roglic G., Green A., Sicree R., King H., Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004 27 5 1047 1053 2-s2.0-2342466734 10.2337/diacare.27.5.1047 (Pubitemid 38579764)
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 17
    • 66149090410 scopus 로고    scopus 로고
    • MiRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57BI/6J male mice
    • 2-s2.0-66149090410 10.1371/journal.pone.0005610 e5610
    • Safdar A., Abadi A., Akhtar M., Hettinga B. P., Tarnopolsky M. A., miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57BI/6J male mice. PLoS ONE 2009 4 5 2-s2.0-66149090410 10.1371/journal.pone. 0005610 e5610
    • (2009) PLoS ONE , vol.4 , Issue.5
    • Safdar, A.1    Abadi, A.2    Akhtar, M.3    Hettinga, B.P.4    Tarnopolsky, M.A.5
  • 18
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • 2-s2.0-58249088751 10.1016/j.cell.2009.01.002
    • Bartel D. P., MicroRNAs: target recognition and regulatory functions. Cell 2009 136 2 215 233 2-s2.0-58249088751 10.1016/j.cell.2009.01.002
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 19
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • 2-s2.0-49949116902 10.1038/nature07242
    • Baek D., Villén J., Shin C., Camargo F. D., Gygi S. P., Bartel D. P., The impact of microRNAs on protein output. Nature 2008 455 7209 64 71 2-s2.0-49949116902 10.1038/nature07242
    • (2008) Nature , vol.455 , Issue.7209 , pp. 64-71
    • Baek, D.1    Villén, J.2    Shin, C.3    Camargo, F.D.4    Gygi, S.P.5    Bartel, D.P.6
  • 20
    • 36248978699 scopus 로고    scopus 로고
    • MicroRNA expression is required for pancreatic islet cell genesis in the mouse
    • DOI 10.2337/db07-0175
    • Lynn F. C., Skewes-Cox P., Kosaka Y., McManus M. T., Harfe B. D., German M. S., MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes 2007 56 12 2938 2945 2-s2.0-36248978699 10.2337/db07-0175 (Pubitemid 350223628)
    • (2007) Diabetes , vol.56 , Issue.12 , pp. 2938-2945
    • Lynn, F.C.1    Skewes-Cox, P.2    Kosaka, Y.3    McManus, M.T.4    Harfe, B.D.5    German, M.S.6
  • 21
    • 58149473947 scopus 로고    scopus 로고
    • Expression of islet-specific microRNAs during human pancreatic development
    • 2-s2.0-58149473947 10.1016/j.gep.2008.10.001
    • Joglekar M. V., Joglekar V. M., Hardikar A. A., Expression of islet-specific microRNAs during human pancreatic development. Gene Expression Patterns 2009 9 2 109 113 2-s2.0-58149473947 10.1016/j.gep.2008.10.001
    • (2009) Gene Expression Patterns , vol.9 , Issue.2 , pp. 109-113
    • Joglekar, M.V.1    Joglekar, V.M.2    Hardikar, A.A.3
  • 23
    • 79952795269 scopus 로고    scopus 로고
    • Diabetes mellitus, a microRNA-related disease?
    • 2-s2.0-79952795269 10.1016/j.trsl.2011.01.009
    • Guay C., Roggli E., Nesca V., Jacovetti C., Regazzi R., Diabetes mellitus, a microRNA-related disease? Translational Research 2011 157 4 253 264 2-s2.0-79952795269 10.1016/j.trsl.2011.01.009
    • (2011) Translational Research , vol.157 , Issue.4 , pp. 253-264
    • Guay, C.1    Roggli, E.2    Nesca, V.3    Jacovetti, C.4    Regazzi, R.5
  • 24
    • 40149083894 scopus 로고    scopus 로고
    • Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs
    • DOI 10.1515/BC.2008.026
    • Lovis P., Gattesco S., Regazzi R., Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs. Biological Chemistry 2008 389 3 305 312 2-s2.0-40149083894 10.1515/BC.2008.026 (Pubitemid 351329024)
    • (2008) Biological Chemistry , vol.389 , Issue.3 , pp. 305-312
    • Lovis, P.1    Gattesco, S.2    Regazzi, R.3
  • 25
    • 34547126004 scopus 로고    scopus 로고
    • MicroRNA-124a regulates foxa2 expression and intracellular signaling in pancreatic β-cell lines
    • DOI 10.1074/jbc.M611841200
    • Baroukh N., Ravier M. A., Loder M. K., Hill E. V., Bounacer A., Scharfmann R., Rutter G. A., Van Obberghen E., MicroRNA-124a regulates foxa2 expression and intracellular signaling in pancreatic β -cell lines. The Journal of Biological Chemistry 2007 282 27 19575 19588 2-s2.0-34547126004 10.1074/jbc.M611841200 (Pubitemid 47100119)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.27 , pp. 19575-19588
    • Baroukh, N.1    Ravier, M.A.2    Loder, M.K.3    Hill, E.V.4    Bounacer, A.5    Scharfmann, R.6    Rutter, G.A.7    Van Obberghen, E.8
  • 26
    • 33748749597 scopus 로고    scopus 로고
    • MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells
    • DOI 10.1074/jbc.M601225200
    • Plaisance V., Abderrahmani A., Perret-Menoud V., Jacquemin P., Lemaigre F., Regazzi R., MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. The Journal of Biological Chemistry 2006 281 37 26932 26942 2-s2.0-33748749597 10.1074/jbc.M601225200 (Pubitemid 44401722)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.37 , pp. 26932-26942
    • Plaisance, V.1    Abderrahmani, A.2    Perret-Menoud, V.3    Jacquemin, P.4    Lemaigre, F.5    Regazzi, R.6
  • 27
    • 84878340278 scopus 로고    scopus 로고
    • How to make a functional beta-cell
    • 10.1242/dev.093187
    • Pagliuca F. W., Melton D. A., How to make a functional beta-cell. Development 2013 140 2472 2483 10.1242/dev.093187
    • (2013) Development , vol.140 , pp. 2472-2483
    • Pagliuca, F.W.1    Melton, D.A.2
  • 28
    • 25444455671 scopus 로고    scopus 로고
    • Regulation of pancreatic beta-cell mass
    • DOI 10.1152/physrev.00025.2004
    • Bouwens L., Rooman I., Regulation of pancreatic beta-cell mass. Physiological Reviews 2005 85 4 1255 1270 2-s2.0-25444455671 10.1152/physrev.00025.2004 (Pubitemid 41362270)
    • (2005) Physiological Reviews , vol.85 , Issue.4 , pp. 1255-1270
    • Bouwens, L.1    Rooman, I.2
  • 29
    • 79953321898 scopus 로고    scopus 로고
    • Neurogenin3: A master regulator of pancreatic islet differentiation and regeneration
    • 2-s2.0-79953321898
    • Rukstalis J. M., Habener J. F., Neurogenin3: a master regulator of pancreatic islet differentiation and regeneration. Islets 2009 1 3 177 184 2-s2.0-79953321898
    • (2009) Islets , vol.1 , Issue.3 , pp. 177-184
    • Rukstalis, J.M.1    Habener, J.F.2
  • 30
    • 0037097981 scopus 로고    scopus 로고
    • Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity
    • DOI 10.1101/gad.985002
    • Lee C. S., Perreault N., Brestelli J. E., Kaestner K. H., Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes & Development 2002 16 12 1488 1497 2-s2.0-0037097981 10.1101/gad.985002 (Pubitemid 34686330)
    • (2002) Genes and Development , vol.16 , Issue.12 , pp. 1488-1497
    • Lee, C.S.1    Perreault, N.2    Brestelli, J.E.3    Kaestner, K.H.4
  • 32
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: MicroRNA biogenesis pathways and their regulation
    • 2-s2.0-61849137222 10.1038/ncb0309-228
    • Winter J., Jung S., Keller S., Gregory R. I., Diederichs S., Many roads to maturity: microRNA biogenesis pathways and their regulation. Nature Cell Biology 2009 11 3 228 234 2-s2.0-61849137222 10.1038/ncb0309-228
    • (2009) Nature Cell Biology , vol.11 , Issue.3 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederichs, S.5
  • 33
    • 35848945091 scopus 로고    scopus 로고
    • MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3
    • DOI 10.1016/j.ydbio.2007.09.008, PII S0012160607013449
    • Joglekar M. V., Parekh V. S., Mehta S., Bhonde R. R., Hardikar A. A., MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Developmental Biology 2007 311 2 603 612 2-s2.0-35848945091 10.1016/j.ydbio.2007.09.008 (Pubitemid 350054939)
    • (2007) Developmental Biology , vol.311 , Issue.2 , pp. 603-612
    • Joglekar, M.V.1    Parekh, V.S.2    Mehta, S.3    Bhonde, R.R.4    Hardikar, A.A.5
  • 34
    • 33644783807 scopus 로고    scopus 로고
    • Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3
    • Lee C. S., de León D. D., Kaestner K. H., Stoffers D. A., Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3. Diabetes 2006 55 2 269 272 2-s2.0-33644783807 (Pubitemid 43343252)
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 269-272
    • Lee, C.S.1    De Leon, D.D.2    Kaestner, K.H.3    Stoffers, D.A.4
  • 35
    • 0028243872 scopus 로고
    • Growth dynamics of pancreatic islet cell populations during fetal and neonatal development of the rat
    • Kaung H.-L. C., Growth dynamics of pancreatic islet cell populations during fetal and neonatal development of the rat. Developmental Dynamics 1994 200 2 163 175 2-s2.0-0028243872 (Pubitemid 24190005)
    • (1994) Developmental Dynamics , vol.200 , Issue.2 , pp. 163-175
    • Kaung, H.-L.C.1
  • 36
    • 0018909901 scopus 로고
    • Pancreatic insulin-, glucagon-, and somatostatin-positive islet cell populations during the perinatal development of the rat. I. Morphometric quantitation
    • McEvoy R. C., Madson K. L., Pancreatic insulin-, glucagon-, and somatostatin-positive islet cell populations during the perinatal development of the rat. I. Morphometric quantitation. Biology of the Neonate 1980 38 5-6 248 254 2-s2.0-0018909901 (Pubitemid 10001246)
    • (1980) Biology of the Neonate , vol.38 , Issue.5-6 , pp. 248-254
    • McEvoy, R.C.1    Madson, K.L.2
  • 37
    • 0019449568 scopus 로고
    • Changes in the volumes of the A-, B-, and D-cell populations in the pancreatic islets during the postnatal development of the rat
    • McEvoy R. C., Changes in the volumes of the A-, B-, and D-cell populations in the pancreatic islets during the postnatal development of the rat. Diabetes 1981 30 10 813 817 2-s2.0-0019449568 (Pubitemid 11020052)
    • (1981) Diabetes , vol.30 , Issue.10 , pp. 813-817
    • McEvoy, R.C.1
  • 38
    • 0033867213 scopus 로고    scopus 로고
    • Linear correlation between β-cell mass and body weight throughout the lifespan in Lewis rats. Role of β-cell hyperplasia and hypertrophy
    • Montanya E., Nacher V., Biarnes M., Soler J., Linear correlation between β -cell mass and body weight throughout the lifespan in Lewis rats: role of β -cell hyperplasia and hypertrophy. Diabetes 2000 49 8 1341 1346 2-s2.0-0033867213 (Pubitemid 30624235)
    • (2000) Diabetes , vol.49 , Issue.8 , pp. 1341-1346
    • Montanya, E.1    Nacher, V.2    Biarnes, M.3    Soler, J.4
  • 39
    • 0029991261 scopus 로고    scopus 로고
    • Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period
    • DOI 10.1007/s001250050477
    • Wang R. N., Bouwens L., Klöppel G., Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period. Diabetologia 1996 39 5 548 557 2-s2.0-0029991261 10.1007/s001250050477 (Pubitemid 26135458)
    • (1996) Diabetologia , vol.39 , Issue.5 , pp. 548-557
    • Wang, R.N.1    Bouwens, L.2    Kloppel, G.3
  • 43
    • 34548284448 scopus 로고    scopus 로고
    • Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development
    • DOI 10.1371/journal.pbio.0050203
    • Kloosterman W. P., Lagendijk A. K., Ketting R. F., Moulton J. D., Plasterk R. H. A., Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biology 2007 5 8 e203 2-s2.0-37349055535 10.1371/journal.pbio.0050203 (Pubitemid 47328277)
    • (2007) PLoS Biology , vol.5 , Issue.8 , pp. 1738-1749
    • Kloosterman, W.P.1    Lagendijk, A.K.2    Ketting, R.F.3    Moulton, J.D.4    Plasterk, R.H.A.5
  • 44
    • 61349122608 scopus 로고    scopus 로고
    • MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas
    • 2-s2.0-61349122608 10.1016/j.gep.2008.12.003
    • Correa-Medina M., Bravo-Egana V., Rosero S., Ricordi C., Edlund H., Diez J., Pastori R. L., MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas. Gene Expression Patterns 2009 9 4 193 199 2-s2.0-61349122608 10.1016/j.gep.2008.12.003
    • (2009) Gene Expression Patterns , vol.9 , Issue.4 , pp. 193-199
    • Correa-Medina, M.1    Bravo-Egana, V.2    Rosero, S.3    Ricordi, C.4    Edlund, H.5    Diez, J.6    Pastori, R.L.7
  • 45
    • 84874432277 scopus 로고    scopus 로고
    • MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic beta-cells
    • 10.2337/db12-0451
    • Wang Y., Liu J., Liu C., Naji A., Stoffers D. A., MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic beta-cells. Diabetes 2013 62 3 887 895 10.2337/db12-0451
    • (2013) Diabetes , vol.62 , Issue.3 , pp. 887-895
    • Wang, Y.1    Liu, J.2    Liu, C.3    Naji, A.4    Stoffers, D.A.5
  • 47
    • 66649096458 scopus 로고    scopus 로고
    • Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic β -cells leads to increased β -cell mass and prevention of hyperglycemia
    • 2-s2.0-66649096458 10.2337/db08-0519
    • Hamada S., Hara K., Hamada T., Yasuda H., Moriyama H., Nakayama R., Nagata M., Yokono K., Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic β -cells leads to increased β -cell mass and prevention of hyperglycemia. Diabetes 2009 58 6 1321 1332 2-s2.0-66649096458 10.2337/db08-0519
    • (2009) Diabetes , vol.58 , Issue.6 , pp. 1321-1332
    • Hamada, S.1    Hara, K.2    Hamada, T.3    Yasuda, H.4    Moriyama, H.5    Nakayama, R.6    Nagata, M.7    Yokono, K.8
  • 48
    • 84860872990 scopus 로고    scopus 로고
    • The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β -cell mass: Implications in the development of type-2 diabetes
    • 2-s2.0-80355125578 10.1007/s00018-011-0874-4
    • Xie J., Herbert T. P., The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β -cell mass: implications in the development of type-2 diabetes. Cellular and Molecular Life Sciences 2012 69 8 1289 1304 2-s2.0-80355125578 10.1007/s00018-011-0874-4
    • (2012) Cellular and Molecular Life Sciences , vol.69 , Issue.8 , pp. 1289-1304
    • Xie, J.1    Herbert, T.P.2
  • 50
    • 44749088201 scopus 로고    scopus 로고
    • β -Cell replication is the primary mechanism subserving the postnatal expansion of β -cell mass in humans
    • 2-s2.0-44749088201 10.2337/db07-1369
    • Meier J. J., Butler A. E., Saisho Y., Monchamp T., Galasso R., Bhushan A., Rizza R. A., Butler P. C., β -cell replication is the primary mechanism subserving the postnatal expansion of β -cell mass in humans. Diabetes 2008 57 6 1584 1594 2-s2.0-44749088201 10.2337/db07-1369
    • (2008) Diabetes , vol.57 , Issue.6 , pp. 1584-1594
    • Meier, J.J.1    Butler, A.E.2    Saisho, Y.3    Monchamp, T.4    Galasso, R.5    Bhushan, A.6    Rizza, R.A.7    Butler, P.C.8
  • 52
    • 52749088737 scopus 로고    scopus 로고
    • HES-1 is involved in adaptation of adult human β -cells to proliferation in vitro
    • 2-s2.0-52749088737 10.2337/db07-1323
    • Bar Y., Russ H. A., Knoller S., Ouziel-Yahalom L., Efrat S., HES-1 is involved in adaptation of adult human β -cells to proliferation in vitro. Diabetes 2008 57 9 2413 2420 2-s2.0-52749088737 10.2337/db07-1323
    • (2008) Diabetes , vol.57 , Issue.9 , pp. 2413-2420
    • Bar, Y.1    Russ, H.A.2    Knoller, S.3    Ouziel-Yahalom, L.4    Efrat, S.5
  • 53
    • 84860363301 scopus 로고    scopus 로고
    • In vitro proliferation of adult human beta-cells
    • 2-s2.0-84860363301 10.1371/journal.pone.0035801 e35801
    • Rutti S., Sauter N. S., Bouzakri K., Prazak R., Halban P. A., Donath M. Y., In vitro proliferation of adult human beta-cells. PLoS ONE 2012 7 4 2-s2.0-84860363301 10.1371/journal.pone.0035801 e35801
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Rutti, S.1    Sauter, N.S.2    Bouzakri, K.3    Prazak, R.4    Halban, P.A.5    Donath, M.Y.6
  • 54
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • 2-s2.0-33644618433 10.1016/j.cmet.2006.01.004
    • Drucker D. J., The biology of incretin hormones. Cell Metabolism 2006 3 3 153 165 2-s2.0-33644618433 10.1016/j.cmet.2006.01.004
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 153-165
    • Drucker, D.J.1
  • 56
    • 48449104756 scopus 로고    scopus 로고
    • Exendin-4 protects β -cells from interleukin-1 β -induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway
    • 2-s2.0-48449104756 10.2337/db07-1214
    • Ferdaoussi M., Abdelli S., Yang J.-Y., Cornu M., Niederhauser G., Favre D., Widmann C., Regazzi R., Thorens B., Waeber G., Abderrahmani A., Exendin-4 protects β -cells from interleukin-1 β -induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes 2008 57 5 1205 1215 2-s2.0-48449104756 10.2337/db07-1214
    • (2008) Diabetes , vol.57 , Issue.5 , pp. 1205-1215
    • Ferdaoussi, M.1    Abdelli, S.2    Yang, J.-Y.3    Cornu, M.4    Niederhauser, G.5    Favre, D.6    Widmann, C.7    Regazzi, R.8    Thorens, B.9    Waeber, G.10    Abderrahmani, A.11
  • 57
    • 84861203551 scopus 로고    scopus 로고
    • Regulation of microRNA-375 by cAMP in pancreatic beta-cells
    • 10.1210/me.2011-1205
    • Keller D. M., Clark E. A., Goodman R. H., Regulation of microRNA-375 by cAMP in pancreatic beta-cells. Molecular Endocrinology 2012 26 6 989 999 10.1210/me.2011-1205
    • (2012) Molecular Endocrinology , vol.26 , Issue.6 , pp. 989-999
    • Keller, D.M.1    Clark, E.A.2    Goodman, R.H.3
  • 58
    • 58149350343 scopus 로고    scopus 로고
    • MiR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic β -Cells
    • 2-s2.0-58149350343 10.2337/db07-1614
    • El Ouaamari A., Baroukh N., Martens G. A., Lebrun P., Pipeleers D., van Obberghen E., MiR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic β -Cells. Diabetes 2008 57 10 2708 2717 2-s2.0-58149350343 10.2337/db07-1614
    • (2008) Diabetes , vol.57 , Issue.10 , pp. 2708-2717
    • El Ouaamari, A.1    Baroukh, N.2    Martens, G.A.3    Lebrun, P.4    Pipeleers, D.5    Van Obberghen, E.6
  • 59
    • 33745480963 scopus 로고    scopus 로고
    • Specific MicroRNAs modulate embryonic stem cell-derived neurogenesis
    • DOI 10.1634/stemcells.2005-0441
    • Krichevsky A. M., Sonntag K.-C., Isacson O., Kosik K. S., Specific MicroRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 2006 24 4 857 864 2-s2.0-33745480963 10.1634/stemcells.2005-0441 (Pubitemid 44464719)
    • (2006) Stem Cells , vol.24 , Issue.4 , pp. 857-864
    • Krichevsky, A.M.1    Sonntag, K.-C.2    Isacson, O.3    Kosik, K.S.4
  • 60
    • 33751297289 scopus 로고    scopus 로고
    • Mechanisms controlling the expression of the components of the exocytotic apparatus under physiological and pathological conditions
    • DOI 10.1042/BST0340696
    • Abderrahmani A., Plaisance V., Lovis P., Regazzi R., Mechanisms controlling the expression of the components of the exocytotic apparatus under physiological and pathological conditions. Biochemical Society Transactions 2006 34 5 696 700 2-s2.0-33751297289 10.1042/BST0340696 (Pubitemid 44796401)
    • (2006) Biochemical Society Transactions , vol.34 , Issue.5 , pp. 696-700
    • Abderrahmani, A.1    Plaisance, V.2    Lovis, P.3    Regazzi, R.4
  • 62
    • 52049103091 scopus 로고    scopus 로고
    • Pancreas islets in metabolic signaling - Focus on the beta-cell
    • 2-s2.0-52049103091 10.2741/3198
    • Suckale J., Solimena M., Pancreas islets in metabolic signaling-focus on the beta-cell. Frontiers in Bioscience 2008 13 18 7156 7171 2-s2.0-52049103091 10.2741/3198
    • (2008) Frontiers in Bioscience , vol.13 , Issue.18 , pp. 7156-7171
    • Suckale, J.1    Solimena, M.2
  • 63
    • 58249107416 scopus 로고    scopus 로고
    • Identification of glucose-regulated miRNAs from pancreatic β cells reveals a role for miR-30d in insulin transcription
    • 2-s2.0-58249107416 10.1261/rna.1211209
    • Tang X., Muniappan L., Tang G., Özcan S., Identification of glucose-regulated miRNAs from pancreatic β cells reveals a role for miR-30d in insulin transcription. RNA 2009 15 2 287 293 2-s2.0-58249107416 10.1261/rna.1211209
    • (2009) RNA , vol.15 , Issue.2 , pp. 287-293
    • Tang, X.1    Muniappan, L.2    Tang, G.3    Özcan, S.4
  • 64
    • 53149104775 scopus 로고    scopus 로고
    • Glucose regulation of insulin gene expression in pancreatic β -cells
    • 2-s2.0-53149104775 10.1042/BJ20081029
    • Andrali S. S., Smapley M. L., Vanderford N. L., Özcan S., Glucose regulation of insulin gene expression in pancreatic β -cells. Biochemical Journal 2008 415 1 1 10 2-s2.0-53149104775 10.1042/BJ20081029
    • (2008) Biochemical Journal , vol.415 , Issue.1 , pp. 1-10
    • Andrali, S.S.1    Smapley, M.L.2    Vanderford, N.L.3    Özcan, S.4
  • 65
    • 84883793279 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
    • 10.1038/nm.3287
    • Xu G., Chen J., Jing G., Shalev A., Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. Nature Medicine 2013 19 1141 1146 10.1038/nm.3287
    • (2013) Nature Medicine , vol.19 , pp. 1141-1146
    • Xu, G.1    Chen, J.2    Jing, G.3    Shalev, A.4
  • 66
    • 33845524266 scopus 로고    scopus 로고
    • Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of β-cells
    • DOI 10.2337/db06-0090
    • Tweedie E., Artner I., Crawford L., Poffenberger G., Thorens B., Stein R., Powers A. C., Gannon M., Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of β -cells. Diabetes 2006 55 12 3264 3270 2-s2.0-33845524266 10.2337/db06-0090 (Pubitemid 44923582)
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3264-3270
    • Tweedie, E.1    Artner, I.2    Crawford, L.3    Poffenberger, G.4    Thorens, B.5    Stein, R.6    Powers, A.C.7    Gannon, M.8
  • 67
    • 0034717337 scopus 로고    scopus 로고
    • Glucose-stimulated preproinsulin gene expression and nuclear trans- location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2
    • DOI 10.1074/jbc.275.21.15977
    • Rafiq I., da Silva Xavier G., Hooper S., Rutter G. A., Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2. The Journal of Biological Chemistry 2000 275 21 15977 15984 2-s2.0-0034717337 10.1074/jbc.275.21.15977 (Pubitemid 30366902)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.21 , pp. 15977-15984
    • Rafiq, I.1    Da Silva Xavier, G.2    Hooper, S.3    Rutter, G.A.4
  • 68
    • 84883687796 scopus 로고    scopus 로고
    • Direct autocrine action of insulin on beta-cells: Does it make physiological sense?
    • 10.2337/db13-0246
    • Rhodes C. J., White M. F., Leahy J. L., Kahn S. E., Direct autocrine action of insulin on beta-cells: does it make physiological sense? Diabetes 2013 62 7 2157 2163 10.2337/db13-0246
    • (2013) Diabetes , vol.62 , Issue.7 , pp. 2157-2163
    • Rhodes, C.J.1    White, M.F.2    Leahy, J.L.3    Kahn, S.E.4
  • 70
    • 84877601932 scopus 로고    scopus 로고
    • When less is more: The forbidden fruits of gene repression in the adult beta-cell
    • 10.1111/dom.12029
    • Pullen T. J., Rutter G. A., When less is more: the forbidden fruits of gene repression in the adult beta-cell. Diabetes, Obesity & Metabolism 2013 15 6 503 512 10.1111/dom.12029
    • (2013) Diabetes, Obesity & Metabolism , vol.15 , Issue.6 , pp. 503-512
    • Pullen, T.J.1    Rutter, G.A.2
  • 71
    • 84863214806 scopus 로고    scopus 로고
    • Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic beta-cells leads to relative hyperinsulinism during exercise
    • 10.2337/db11-1531
    • Pullen T. J., Sylow L., Sun G., Halestrap A. P., Richter E. A., Rutter G. A., Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic beta-cells leads to relative hyperinsulinism during exercise. Diabetes 2012 61 7 1719 1725 10.2337/db11-1531
    • (2012) Diabetes , vol.61 , Issue.7 , pp. 1719-1725
    • Pullen, T.J.1    Sylow, L.2    Sun, G.3    Halestrap, A.P.4    Richter, E.A.5    Rutter, G.A.6
  • 72
    • 0026573783 scopus 로고
    • Adaptation of islets of Langerhans to pregnancy: Increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion
    • 2-s2.0-0026573783 10.1210/en.130.3.1459
    • Parsons J. A., Brelje T. C., Sorenson R. L., Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion. Endocrinology 1992 130 3 1459 1466 2-s2.0-0026573783 10.1210/en.130.3.1459
    • (1992) Endocrinology , vol.130 , Issue.3 , pp. 1459-1466
    • Parsons, J.A.1    Brelje, T.C.2    Sorenson, R.L.3
  • 73
    • 77949324263 scopus 로고    scopus 로고
    • Expansion of β -cell mass in response to pregnancy
    • 2-s2.0-77949324263 10.1016/j.tem.2009.11.001
    • Rieck S., Kaestner K. H., Expansion of β -cell mass in response to pregnancy. Trends in Endocrinology and Metabolism 2010 21 3 151 158 2-s2.0-77949324263 10.1016/j.tem.2009.11.001
    • (2010) Trends in Endocrinology and Metabolism , vol.21 , Issue.3 , pp. 151-158
    • Rieck, S.1    Kaestner, K.H.2
  • 75
    • 84873689087 scopus 로고    scopus 로고
    • Compensatory beta-cell mass expansion: A big role for a tiny actor
    • 10.4161/cc.23378
    • Jacovetti C., Regazzi R., Compensatory beta-cell mass expansion: a big role for a tiny actor. Cell Cycle 2013 12 2 197 198 10.4161/cc.23378
    • (2013) Cell Cycle , vol.12 , Issue.2 , pp. 197-198
    • Jacovetti, C.1    Regazzi, R.2
  • 76
    • 77958040076 scopus 로고    scopus 로고
    • Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy
    • 2-s2.0-77958040076 10.1007/s00125-010-1809-6
    • Butler A. E., Cao-Minh L., Galasso R., Rizza R. A., Corradin A., Cobelli C., Butler P. C., Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy. Diabetologia 2010 53 10 2167 2176 2-s2.0-77958040076 10.1007/s00125-010-1809-6
    • (2010) Diabetologia , vol.53 , Issue.10 , pp. 2167-2176
    • Butler, A.E.1    Cao-Minh, L.2    Galasso, R.3    Rizza, R.A.4    Corradin, A.5    Cobelli, C.6    Butler, P.C.7
  • 77
    • 2542479899 scopus 로고    scopus 로고
    • Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
    • DOI 10.1210/en.2004-0015
    • Brubaker P. L., Drucker D. J., Minireview: glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology 2004 145 6 2653 2659 2-s2.0-2542479899 10.1210/en.2004-0015 (Pubitemid 38686211)
    • (2004) Endocrinology , vol.145 , Issue.6 , pp. 2653-2659
    • Brubaker, P.L.1    Drucker, D.J.2
  • 79
    • 70450211212 scopus 로고    scopus 로고
    • The role of oestrogens in the adaptation of islets to insulin resistance
    • 2-s2.0-70450211212 10.1113/jphysiol.2009.177188
    • Nadal A., Alonso-Magdalena P., Soriano S., Ropero A. B., Quesada I., The role of oestrogens in the adaptation of islets to insulin resistance. The Journal of Physiology 2009 587 21 5031 5037 2-s2.0-70450211212 10.1113/jphysiol.2009.177188
    • (2009) The Journal of Physiology , vol.587 , Issue.21 , pp. 5031-5037
    • Nadal, A.1    Alonso-Magdalena, P.2    Soriano, S.3    Ropero, A.B.4    Quesada, I.5
  • 80
    • 0034686028 scopus 로고    scopus 로고
    • Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia
    • DOI 10.1074/jbc.275.20.15399
    • Vasavada R. C., Garcia-Ocaña A., Zawalich W. S., Sorenson R. L., Dann P., Syed M., Ogren L., Talamantes F., Stewart A. F., Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia. The Journal of Biological Chemistry 2000 275 20 15399 15406 2-s2.0-0034686028 10.1074/jbc.275.20.15399 (Pubitemid 30337270)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.20 , pp. 15399-15406
    • Vasavada, R.C.1    Garcia-Ocana, A.2    Zawalich, W.S.3    Sorenson, R.L.4    Dann, P.5    Syed, M.6    Ogren, L.7    Talamantes, F.8    Stewart, A.F.9
  • 81
    • 0035130272 scopus 로고    scopus 로고
    • β-Cell adaptation and decompensation during the progression of diabetes
    • Weir G. C., Laybutt D. R., Kaneto H., Bonner-Weir S., Sharma A., β -cell adaptation and decompensation during the progression of diabetes. Diabetes 2001 50 supplement 1 S154 S159 2-s2.0-0035130272 (Pubitemid 32148243)
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Weir, G.C.1    Laybutt, D.R.2    Kaneto, H.3    Bonner-Weir, S.4    Sharma, A.5
  • 82
    • 84876565085 scopus 로고    scopus 로고
    • Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes
    • 10.2337/db12-0701
    • Chan J. Y., Luzuriaga J., Bensellam M., Biden T. J., Laybutt D. R., Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes. Diabetes 2013 62 5 1557 1568 10.2337/db12-0701
    • (2013) Diabetes , vol.62 , Issue.5 , pp. 1557-1568
    • Chan, J.Y.1    Luzuriaga, J.2    Bensellam, M.3    Biden, T.J.4    Laybutt, D.R.5
  • 83
    • 0033956846 scopus 로고    scopus 로고
    • The db/db mouse, a model for diabetic dyslipidemia: Molecular characterization and effects of western diet feeding
    • Kobayashi K., Forte T. M., Taniguchi S., Ishida B. Y., Oka K., Chan L., The db/db db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding. Metabolism 2000 49 1 22 31 2-s2.0-0033956846 10.1016/S0026-0495(00)90588-2 (Pubitemid 30054029)
    • (2000) Metabolism: Clinical and Experimental , vol.49 , Issue.1 , pp. 22-31
    • Kobayashi, K.1    Forte, T.M.2    Taniguchi, S.3    Ishida, B.Y.4    Oka, K.5    Chan, L.6
  • 84
    • 84890124194 scopus 로고    scopus 로고
    • Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes
    • 10.1007/s00125-013-2993-y
    • Nesca V., Guay C., Jacovetti C., Menoud V., Peyot M., Laybutt D. R., Prentki M., Regazzi R., Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes. Diabetologia 2013 56 10 2203 2212 10.1007/s00125-013-2993-y
    • (2013) Diabetologia , vol.56 , Issue.10 , pp. 2203-2212
    • Nesca, V.1    Guay, C.2    Jacovetti, C.3    Menoud, V.4    Peyot, M.5    Laybutt, D.R.6    Prentki, M.7    Regazzi, R.8
  • 85
    • 84891043328 scopus 로고    scopus 로고
    • Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion
    • 10.1007/s00125-013-3089-4
    • Locke J. M., da Silva Xavier G., Dawe H. R., Rutter G. A., Harries L. W., Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion. Diabetologia 2014 57 1 122 128 10.1007/s00125-013-3089-4
    • (2014) Diabetologia , vol.57 , Issue.1 , pp. 122-128
    • Locke, J.M.1    Da Silva Xavier, G.2    Dawe, H.R.3    Rutter, G.A.4    Harries, L.W.5
  • 86
    • 50449086746 scopus 로고    scopus 로고
    • Obesity and free fatty acids
    • 2-s2.0-50449086746 10.1016/j.ecl.2008.06.007
    • Boden G., Obesity and free fatty acids. Endocrinology and Metabolism Clinics of North America 2008 37 3 635 646 2-s2.0-50449086746 10.1016/j.ecl.2008.06.007
    • (2008) Endocrinology and Metabolism Clinics of North America , vol.37 , Issue.3 , pp. 635-646
    • Boden, G.1
  • 87
    • 0030759095 scopus 로고    scopus 로고
    • The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: Results of the Paris Prospective study
    • DOI 10.1007/s001250050793
    • Charles M. A., Eschwège E., Thibult N., Claude J.-R., Warnet J.-M., Rosselin G. E., Girard J., Balkau B., The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: results of the Paris prospective study. Diabetologia 1997 40 9 1101 1106 2-s2.0-0030759095 10.1007/s001250050793 (Pubitemid 27381974)
    • (1997) Diabetologia , vol.40 , Issue.9 , pp. 1101-1106
    • Charles, M.A.1    Eschwege, E.2    Thibult, N.3    Claude, J.-R.4    Warnet, J.-M.5    Rosselin, G.E.6    Girard, J.7    Balkau, B.8
  • 88
    • 24144496798 scopus 로고    scopus 로고
    • Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
    • DOI 10.2337/diabetes.54.9.2755
    • Kjørholt C., Åkerfeldt M. C., Biden T. J., Laybutt D. R., Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β -cell differentiation and secretory function in the db/db mouse model of diabetes. Diabetes 2005 54 9 2755 2763 2-s2.0-24144496798 10.2337/diabetes.54.9.2755 (Pubitemid 41233599)
    • (2005) Diabetes , vol.54 , Issue.9 , pp. 2755-2763
    • Kjorholt, C.1    Akerfeldt, M.C.2    Biden, T.J.3    Laybutt, D.R.4
  • 89
    • 41149115561 scopus 로고    scopus 로고
    • Islet inflammation in type 2 diabetes: From metabolic stress to therapy
    • supplement 2 2-s2.0-41149115561
    • Donath M. Y., Schumann D. M., Faulenbach M., Ellingsgaard H., Perren A., Ehses J. A., Islet inflammation in type 2 diabetes: from metabolic stress to therapy. Diabetes Care 2008 31 supplement 2 S161 S164 2-s2.0-41149115561
    • (2008) Diabetes Care , vol.31
    • Donath, M.Y.1    Schumann, D.M.2    Faulenbach, M.3    Ellingsgaard, H.4    Perren, A.5    Ehses, J.A.6
  • 90
    • 53849106114 scopus 로고    scopus 로고
    • Glucolipotoxicity of the pancreatic β -cell: Myth or reality?
    • 2-s2.0-53849106114 10.1042/BST0360901
    • Poitout V., Glucolipotoxicity of the pancreatic β -cell: myth or reality? Biochemical Society Transactions 2008 36 5 901 904 2-s2.0-53849106114 10.1042/BST0360901
    • (2008) Biochemical Society Transactions , vol.36 , Issue.5 , pp. 901-904
    • Poitout, V.1
  • 91
    • 58149350340 scopus 로고    scopus 로고
    • Alterations in microRNA expression contribute to fatty acid-induced pancreatic β -Cell dysfunction
    • 2-s2.0-58149350340 10.2337/db07-1252
    • Lovis P., Roggli E., Laybutt D. R., Gattesco S., Yang J.-Y., Widmann C., Abderrahmani A., Regazzi R., Alterations in microRNA expression contribute to fatty acid-induced pancreatic β -Cell dysfunction. Diabetes 2008 57 10 2728 2736 2-s2.0-58149350340 10.2337/db07-1252
    • (2008) Diabetes , vol.57 , Issue.10 , pp. 2728-2736
    • Lovis, P.1    Roggli, E.2    Laybutt, D.R.3    Gattesco, S.4    Yang, J.-Y.5    Widmann, C.6    Abderrahmani, A.7    Regazzi, R.8
  • 93
    • 77951158889 scopus 로고    scopus 로고
    • Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic β -cells
    • 2-s2.0-77951158889 10.2337/db09-0881
    • Roggli E., Britan A., Gattesco S., Lin-Marq N., Abderrahmani A., Meda P., Regazzi R., Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic β -cells. Diabetes 2010 59 4 978 986 2-s2.0-77951158889 10.2337/db09-0881
    • (2010) Diabetes , vol.59 , Issue.4 , pp. 978-986
    • Roggli, E.1    Britan, A.2    Gattesco, S.3    Lin-Marq, N.4    Abderrahmani, A.5    Meda, P.6    Regazzi, R.7
  • 94
    • 34247866358 scopus 로고    scopus 로고
    • Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells
    • DOI 10.1007/s00125-007-0642-z
    • Abderrahmani A., Niederhauser G., Favre D., Abdelli S., Ferdaoussi M., Yang J. Y., Regazzi R., Widmann C., Waeber G., Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells. Diabetologia 2007 50 6 1304 1314 2-s2.0-34247866358 10.1007/s00125-007-0642-z (Pubitemid 46701553)
    • (2007) Diabetologia , vol.50 , Issue.6 , pp. 1304-1314
    • Abderrahmani, A.1    Niederhauser, G.2    Favre, D.3    Abdelli, S.4    Ferdaoussi, M.5    Yang, J.Y.6    Regazzi, R.7    Widmann, C.8    Waeber, G.9
  • 95
    • 80054707772 scopus 로고    scopus 로고
    • Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets
    • 2-s2.0-80054707772 10.1007/s00125-011-2165-x
    • Favre D., Niederhauser G., Fahmi D., Plaisance V., Brajkovic S., Beeler N., Allagnat F., Haefliger J. A., Regazzi R., Waeber G., Abderrahmani A., Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets. Diabetologia 2011 54 9 2337 2346 2-s2.0-80054707772 10.1007/s00125-011-2165-x
    • (2011) Diabetologia , vol.54 , Issue.9 , pp. 2337-2346
    • Favre, D.1    Niederhauser, G.2    Fahmi, D.3    Plaisance, V.4    Brajkovic, S.5    Beeler, N.6    Allagnat, F.7    Haefliger, J.A.8    Regazzi, R.9    Waeber, G.10    Abderrahmani, A.11
  • 96
    • 84873844411 scopus 로고    scopus 로고
    • Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles
    • e55198 10.1371/journal.pone.0055198
    • Haefliger J. A., Martin D., Favre D., Petremand Y., Mazzolai L., Abderrahmani A., Meda P., Waeber G., Allagnat F., Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles. PloS ONE 2013 8 1 e55198 10.1371/journal.pone.0055198
    • (2013) PloS ONE , vol.8 , Issue.1
    • Haefliger, J.A.1    Martin, D.2    Favre, D.3    Petremand, Y.4    Mazzolai, L.5    Abderrahmani, A.6    Meda, P.7    Waeber, G.8    Allagnat, F.9
  • 97
    • 1842527452 scopus 로고    scopus 로고
    • The Metabolic Syndrome, Circulating Oxidized LDL, and Risk of Myocardial Infarction in Well-Functioning Elderly People in the Health, Aging, and Body Composition Cohort
    • DOI 10.2337/diabetes.53.4.1068
    • Holvoet P., Kritchevsky S. B., Tracy R. P., Mertens A., Rubin S. M., Butler J., Goodpaster B., Harriss T. B., The metabolic syndrome, circulating oxidized LDL, and risk of myocardial infarction in well-functioning elderly people in the health, aging, and body composition cohort. Diabetes 2004 53 4 1068 1073 2-s2.0-1842527452 10.2337/diabetes.53.4.1068 (Pubitemid 38436620)
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1068-1073
    • Holvoet, P.1    Kritchevsky, S.B.2    Tracy, R.P.3    Mertens, A.4    Rubin, S.M.5    Butler, J.6    Goodpaster, B.7    Harriss, T.B.8
  • 98
    • 77953289382 scopus 로고    scopus 로고
    • Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol
    • 2-s2.0-77953289382 10.1007/s11745-010-3401-8
    • Nakhjavani M., Khalilzadeh O., Khajeali L., Esteghamati A., Morteza A., Jamali A., Dadkhahipour S., Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol. Lipids 2010 45 4 321 327 2-s2.0-77953289382 10.1007/s11745-010-3401-8
    • (2010) Lipids , vol.45 , Issue.4 , pp. 321-327
    • Nakhjavani, M.1    Khalilzadeh, O.2    Khajeali, L.3    Esteghamati, A.4    Morteza, A.5    Jamali, A.6    Dadkhahipour, S.7
  • 99
    • 0028985195 scopus 로고
    • Antoantibodies against oxidatively modified low-density lipoproteins in NIDDM
    • 2-s2.0-0028985195
    • Bellomo G., Maggi E., Poli M., Agosta F. G., Bollati P., Finardi G., Antoantibodies against oxidatively modified low-density lipoproteins in NIDDM. Diabetes 1995 44 1 60 66 2-s2.0-0028985195
    • (1995) Diabetes , vol.44 , Issue.1 , pp. 60-66
    • Bellomo, G.1    Maggi, E.2    Poli, M.3    Agosta, F.G.4    Bollati, P.5    Finardi, G.6
  • 100
    • 38849201796 scopus 로고    scopus 로고
    • Cholesterol in islet dysfunction and type 2 diabetes
    • DOI 10.1172/JCI33296
    • Brunham L. R., Kruit J. K., Verchere C. B., Hayden M. R., Cholesterol in islet dysfunction and type 2 diabetes. The Journal of Clinical Investigation 2008 118 2 403 408 2-s2.0-38849201796 10.1172/JCI33296 (Pubitemid 351206525)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.2 , pp. 403-408
    • Brunham, L.R.1    Kruit, J.K.2    Verchere, C.B.3    Hayden, M.R.4
  • 103
    • 70349320177 scopus 로고    scopus 로고
    • Low- and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic β -cells
    • 2-s2.0-70349320177 10.1210/en.2009-0252
    • Rütti S., Ehses J. A., Sibler R. A., Prazak R., Rohrer L., Georgopoulos S., Meier D. T., Niclauss N., Thierry B., Donath M. Y., von Eckardstein A., Low- and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic β -cells. Endocrinology 2009 150 10 4521 4530 2-s2.0-70349320177 10.1210/en.2009-0252
    • (2009) Endocrinology , vol.150 , Issue.10 , pp. 4521-4530
    • Rütti, S.1    Ehses, J.A.2    Sibler, R.A.3    Prazak, R.4    Rohrer, L.5    Georgopoulos, S.6    Meier, D.T.7    Niclauss, N.8    Thierry, B.9    Donath, M.Y.10    Von Eckardstein, A.11
  • 105
    • 77956266047 scopus 로고    scopus 로고
    • The emerging genetics of type 2 diabetes
    • 2-s2.0-77956266047 10.1016/j.molmed.2010.06.004
    • Bonnefond A., Froguel P., Vaxillaire M., The emerging genetics of type 2 diabetes. Trends in Molecular Medicine 2010 16 9 407 416 2-s2.0-77956266047 10.1016/j.molmed.2010.06.004
    • (2010) Trends in Molecular Medicine , vol.16 , Issue.9 , pp. 407-416
    • Bonnefond, A.1    Froguel, P.2    Vaxillaire, M.3
  • 108
    • 0034663750 scopus 로고    scopus 로고
    • Molecular targets of a human HNF1α mutation responsible for pancreatic β-cell dysfunction
    • Wang H., Antinozzi P. A., Hagenfeldt K. A., Maechler P., Wollheim C. B., Molecular targets of a human HNF1 α mutation responsible for pancreatic β -cell dysfunction. The EMBO Journal 2000 19 16 4257 4264 2-s2.0-0034663750 (Pubitemid 30623736)
    • (2000) EMBO Journal , vol.19 , Issue.16 , pp. 4257-4264
    • Wang, H.1    Antinozzi, P.A.2    Hagenfeldt, K.A.3    Maechler, P.4    Wollheim, C.B.5
  • 109
    • 84865581182 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction
    • supplement 3 10.1111/j.1463-1326.2012.01654.x
    • Guay C., Jacovetti C., Nesca V., Motterle A., Tugay K., Regazzi R., Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction. Diabetes, Obesity & Metabolism 2012 14 supplement 3 12 21 10.1111/j.1463-1326.2012.01654.x
    • (2012) Diabetes, Obesity & Metabolism , vol.14 , pp. 12-21
    • Guay, C.1    Jacovetti, C.2    Nesca, V.3    Motterle, A.4    Tugay, K.5    Regazzi, R.6
  • 112
    • 84880652927 scopus 로고    scopus 로고
    • Targeting long non-coding RNA to therapeutically upregulate gene expression
    • 10.1038/nrd4018
    • Wahlestedt C., Targeting long non-coding RNA to therapeutically upregulate gene expression. Nature Reviews Drug Discovery 2013 12 433 446 10.1038/nrd4018
    • (2013) Nature Reviews Drug Discovery , vol.12 , pp. 433-446
    • Wahlestedt, C.1
  • 113
    • 84875177348 scopus 로고    scopus 로고
    • X-inactivation, imprinting, and long noncoding RNAs in health and disease
    • 10.1016/j.cell.2013.02.016
    • Lee J. T., Bartolomei M. S., X-inactivation, imprinting, and long noncoding RNAs in health and disease. Cell 2013 152 6 1308 1323 10.1016/j.cell.2013.02.016
    • (2013) Cell , vol.152 , Issue.6 , pp. 1308-1323
    • Lee, J.T.1    Bartolomei, M.S.2
  • 114
    • 84875200257 scopus 로고    scopus 로고
    • Long noncoding RNAs: Cellular address codes in development and disease
    • 10.1016/j.cell.2013.02.012
    • Batista P. J., Chang H. Y., Long noncoding RNAs: cellular address codes in development and disease. Cell 2013 152 6 1298 1307 10.1016/j.cell.2013.02.012
    • (2013) Cell , vol.152 , Issue.6 , pp. 1298-1307
    • Batista, P.J.1    Chang, H.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.