-
1
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
DOI 10.2337/diabetes.52.1.102
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased betacell apoptosis in humans with type 2 diabetes. Diabetes. 2003;52(1):102-110. (Pubitemid 36042113)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
2
-
-
33745863033
-
Islet beta cell failure in type 2 diabetes
-
DOI 10.1172/JCI29103
-
Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest. 2006;116(7):1802-1812. (Pubitemid 44033300)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
3
-
-
79952369836
-
Ongoing beta-cell turnover in adult nonhuman primates is not adaptively increased in streptozotocin-induced diabetes
-
Saisho Y, et al. Ongoing beta-cell turnover in adult nonhuman primates is not adaptively increased in streptozotocin-induced diabetes. Diabetes. 2011;60(3):848-856.
-
(2011)
Diabetes
, vol.60
, Issue.3
, pp. 848-856
-
-
Saisho, Y.1
-
4
-
-
63049137246
-
Slow and steady is the key to beta-cell replication
-
Brennand K, Melton D. Slow and steady is the key to beta-cell replication. J Cell Mol Med. 2009;13(3):472-487.
-
(2009)
J Cell Mol Med
, vol.13
, Issue.3
, pp. 472-487
-
-
Brennand, K.1
Melton, D.2
-
5
-
-
12344323484
-
Type 2 diabetes - A matter of beta-cell life and death?
-
DOI 10.1126/science.1104345
-
Rhodes CJ. Type 2 diabetes-a matter of beta-cell life and death? Science. 2005;307(5708):380-384. (Pubitemid 40139973)
-
(2005)
Science
, vol.307
, Issue.5708
, pp. 380-384
-
-
Rhodes, C.J.1
-
6
-
-
66449093171
-
Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion
-
Sachdeva MM, Stoffers DA. Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion. Mol Endocrinol. 2009;23(6):747-758.
-
(2009)
Mol Endocrinol
, vol.23
, Issue.6
, pp. 747-758
-
-
Sachdeva, M.M.1
Stoffers, D.A.2
-
7
-
-
77950290798
-
{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes
-
Hanley SC, et al. {beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes. Endocrinology. 2010;151(4):1462-1472.
-
(2010)
Endocrinology
, vol.151
, Issue.4
, pp. 1462-1472
-
-
Hanley, S.C.1
-
8
-
-
79960202841
-
Type 2 diabetes across generations: From pathophysiology to prevention and management
-
Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet. 2011; 378(9786):169-181.
-
(2011)
Lancet
, vol.378
, Issue.9786
, pp. 169-181
-
-
Nolan, C.J.1
Damm, P.2
Prentki, M.3
-
9
-
-
0026573783
-
Adaptation of islets of Langerhans to pregnancy: Increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion
-
Parsons JA, Brelje TC, Sorenson RL. Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion. Endocrinology. 1992;130(3):1459-1466.
-
(1992)
Endocrinology
, vol.130
, Issue.3
, pp. 1459-1466
-
-
Parsons, J.A.1
Brelje, T.C.2
Sorenson, R.L.3
-
11
-
-
77958040076
-
Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy
-
Butler AE, et al. Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy. Diabetologia. 2010;53(10):2167-2176.
-
(2010)
Diabetologia
, vol.53
, Issue.10
, pp. 2167-2176
-
-
Butler, A.E.1
-
12
-
-
77949324263
-
Expansion of beta-cell mass in response to pregnancy
-
Rieck S, Kaestner KH. Expansion of beta-cell mass in response to pregnancy. Trends Endocrinol Metab. 2010;21(3):151-158.
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.3
, pp. 151-158
-
-
Rieck, S.1
Kaestner, K.H.2
-
13
-
-
0028845665
-
Apoptosis contributes to the involution of beta cell mass in the post partum rat pancreas
-
Scaglia L, Smith FE, Bonner-Weir S. Apoptosis contributes to the involution of beta cell mass in the post partum rat pancreas. Endocrinology. 1995;136(12):5461-5468.
-
(1995)
Endocrinology
, vol.136
, Issue.12
, pp. 5461-5468
-
-
Scaglia, L.1
Smith, F.E.2
Bonner-Weir, S.3
-
14
-
-
63849322132
-
Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy
-
Huang C, Snider F, Cross JC. Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy. Endocrinology. 2009;150(4):1618-1626.
-
(2009)
Endocrinology
, vol.150
, Issue.4
, pp. 1618-1626
-
-
Huang, C.1
Snider, F.2
Cross, J.C.3
-
15
-
-
38449099624
-
Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus
-
DOI 10.1126/science.1146812
-
Karnik SK, et al. Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus. Science. 2007;318(5851):806-809. (Pubitemid 351411773)
-
(2007)
Science
, vol.318
, Issue.5851
, pp. 806-809
-
-
Karnik, S.K.1
Chen, H.2
McLean, G.W.3
Heit, J.J.4
Gu, X.5
Zhang, A.Y.6
Fontaine, M.7
Yen, M.H.8
Kim, S.K.9
-
16
-
-
77449086017
-
Gestational diabetes mellitus resulting from impaired beta-cell compensation in the absence of FoxM1, a novel downstream effector of placental lactogen
-
Zhang H, et al. Gestational diabetes mellitus resulting from impaired beta-cell compensation in the absence of FoxM1, a novel downstream effector of placental lactogen. Diabetes. 2010;59(1):143-152.
-
(2010)
Diabetes
, vol.59
, Issue.1
, pp. 143-152
-
-
Zhang, H.1
-
17
-
-
77954480533
-
Serotonin regulates pancreatic beta cell mass during pregnancy
-
Kim H, et al. Serotonin regulates pancreatic beta cell mass during pregnancy. Nat Med. 2010; 16(7):804-808.
-
(2010)
Nat Med
, vol.16
, Issue.7
, pp. 804-808
-
-
Kim, H.1
-
18
-
-
78649329990
-
Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy
-
Schraenen A, et al. Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy. Diabetologia. 2010;53(12):2589-2599.
-
(2010)
Diabetologia
, vol.53
, Issue.12
, pp. 2589-2599
-
-
Schraenen, A.1
-
19
-
-
77956102457
-
FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation
-
Davis DB, et al. FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Mol Endocrinol. 2010;24(9):1822-1834.
-
(2010)
Mol Endocrinol
, vol.24
, Issue.9
, pp. 1822-1834
-
-
Davis, D.B.1
-
20
-
-
0027504201
-
Effects of steroid and lactogenic hormones on islets of Langerhans: A new hypothesis for the role of pregnancy steroids in the adaptation of islets to pregnancy
-
DOI 10.1210/en.133.5.2227
-
Sorenson RL, Brelje TC, Roth C. Effects of steroid and lactogenic hormones on islets of Langerhans: a new hypothesis for the role of pregnancy steroids in the adaptation of islets to pregnancy. Endocrinology. 1993;133(5):2227-2234. (Pubitemid 23324731)
-
(1993)
Endocrinology
, vol.133
, Issue.5
, pp. 2227-2234
-
-
Sorenson, R.L.1
Brelje, T.C.2
Roth, C.3
-
21
-
-
43849096860
-
Beneficial effects of lipids and prolactin on insulin secretion and beta-cell proliferation: A role for lipids in the adaptation of islets to pregnancy
-
DOI 10.1677/JOE-07-0657
-
Brelje TC, Bhagroo NV, Stout LE, Sorenson RL. Beneficial effects of lipids and prolactin on insulin secretion and beta-cell proliferation: a role for lipids in the adaptation of islets to pregnancy. J Endocrinol. 2008;197(2):265-276. (Pubitemid 351696239)
-
(2008)
Journal of Endocrinology
, vol.197
, Issue.2
, pp. 265-276
-
-
Brelje, T.C.1
Bhagroo, N.V.2
Stout, L.E.3
Sorenson, R.L.4
-
22
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215-233.
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 215-233
-
-
Bartel, D.P.1
-
23
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP. The impact of microRNAs on protein output. Nature. 2008;455(7209):64-71.
-
(2008)
Nature
, vol.455
, Issue.7209
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
24
-
-
36248978699
-
MicroRNA expression is required for pancreatic islet cell genesis in the mouse
-
DOI 10.2337/db07-0175
-
Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS. MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007;56(12):2938-2945. (Pubitemid 350223628)
-
(2007)
Diabetes
, vol.56
, Issue.12
, pp. 2938-2945
-
-
Lynn, F.C.1
Skewes-Cox, P.2
Kosaka, Y.3
McManus, M.T.4
Harfe, B.D.5
German, M.S.6
-
25
-
-
58149473947
-
Expression of islet-specific microRNAs during human pancreatic development
-
Joglekar MV, Joglekar VM, Hardikar AA. Expression of islet-specific microRNAs during human pancreatic development. Gene Expr Patterns. 2009; 9(2):109-113.
-
(2009)
Gene Expr Patterns
, vol.9
, Issue.2
, pp. 109-113
-
-
Joglekar, M.V.1
Joglekar, V.M.2
Hardikar, A.A.3
-
26
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
DOI 10.1038/nature03076
-
Poy MN, et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature. 2004; 432(7014):226-230. (Pubitemid 39545853)
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
MacDonald, P.E.6
Pfeffer, S.7
Tuschl, T.8
Rajewsky, N.9
Rorsman, P.10
Stoffel, M.11
-
27
-
-
79952795269
-
Diabetes mellitus, a microRNA-related disease?
-
Guay C, Roggli E, Nesca V, Jacovetti C, Regazzi R. Diabetes mellitus, a microRNA-related disease? Transl Res. 2011;157(4):253-264.
-
(2011)
Transl Res
, vol.157
, Issue.4
, pp. 253-264
-
-
Guay, C.1
Roggli, E.2
Nesca, V.3
Jacovetti, C.4
Regazzi, R.5
-
28
-
-
40149083894
-
Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs
-
DOI 10.1515/BC.2008.026
-
Lovis P, Gattesco S, Regazzi R. Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs. Biol Chem. 2008;389(3):305-312. (Pubitemid 351329024)
-
(2008)
Biological Chemistry
, vol.389
, Issue.3
, pp. 305-312
-
-
Lovis, P.1
Gattesco, S.2
Regazzi, R.3
-
29
-
-
34547126004
-
MicroRNA-124a regulates foxa2 expression and intracellular signaling in pancreatic beta-cell lines
-
DOI 10.1074/jbc.M611841200
-
Baroukh N, et al. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J Biol Chem. 2007; 282(27):19575-19588. (Pubitemid 47100119)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19575-19588
-
-
Baroukh, N.1
Ravier, M.A.2
Loder, M.K.3
Hill, E.V.4
Bounacer, A.5
Scharfmann, R.6
Rutter, G.A.7
Van Obberghen, E.8
-
30
-
-
58149350340
-
Alterations in microRNA expression contribute to fatty acid-induced pancreatic betacell dysfunction
-
Lovis P, et al. Alterations in microRNA expression contribute to fatty acid-induced pancreatic betacell dysfunction. Diabetes. 2008;57(10):2728-2736.
-
(2008)
Diabetes
, vol.57
, Issue.10
, pp. 2728-2736
-
-
Lovis, P.1
-
31
-
-
77951158889
-
Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells
-
Roggli E, et al. Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes. 2010;59(4):978-986.
-
(2010)
Diabetes
, vol.59
, Issue.4
, pp. 978-986
-
-
Roggli, E.1
-
32
-
-
65249093130
-
MiR-375 maintains normal pancreatic alpha- and beta-cell mass
-
Poy MN, et al. miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci U S A. 2009;106(14):5813-5818.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.14
, pp. 5813-5818
-
-
Poy, M.N.1
-
33
-
-
84860363301
-
In vitro proliferation of adult human beta-cells
-
Rutti S, Sauter NS, Bouzakri K, Prazak R, Halban PA, Donath MY. In vitro proliferation of adult human beta-cells. PLoS One. 2012;7(4):e35801.
-
(2012)
PLoS One
, vol.7
, Issue.4
-
-
Rutti, S.1
Sauter, N.S.2
Bouzakri, K.3
Prazak, R.4
Halban, P.A.5
Donath, M.Y.6
-
34
-
-
36649000083
-
Proliferation of sorted human and rat beta cells
-
DOI 10.1007/s00125-007-0855-1
-
Parnaud G, et al. Proliferation of sorted human and rat beta cells. Diabetologia. 2008;51(1):91-100. (Pubitemid 50002201)
-
(2008)
Diabetologia
, vol.51
, Issue.1
, pp. 91-100
-
-
Parnaud, G.1
Bosco, D.2
Berney, T.3
Pattou, F.4
Kerr-Conte, J.5
Donath, M.Y.6
Bruun, C.7
Mandrup-Poulsen, T.8
Billestrup, N.9
Halban, P.A.10
-
35
-
-
77952488104
-
Cytokine production by islets in health and diabetes: Cellular origin, regulation and function
-
Donath MY, Boni-Schnetzler M, Ellingsgaard H, Halban PA, Ehses JA. Cytokine production by islets in health and diabetes: cellular origin, regulation and function. Trends Endocrinol Metab. 2010;21(5):261-267.
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.5
, pp. 261-267
-
-
Donath, M.Y.1
Boni-Schnetzler, M.2
Ellingsgaard, H.3
Halban, P.A.4
Ehses, J.A.5
-
36
-
-
43249096519
-
Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes
-
Pirot P, Cardozo AK, Eizirik DL. Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes. Arq Bras Endocrinol Metabol. 2008;52(2):156-165.
-
(2008)
Arq Bras Endocrinol Metabol
, vol.52
, Issue.2
, pp. 156-165
-
-
Pirot, P.1
Cardozo, A.K.2
Eizirik, D.L.3
-
37
-
-
70450211212
-
The role of oestrogens in the adaptation of islets to insulin resistance
-
Nadal A, Alonso-Magdalena P, Soriano S, Ropero AB, Quesada I. The role of oestrogens in the adaptation of islets to insulin resistance. J Physiol. 2009;587(pt 21):5031-5037.
-
(2009)
J Physiol
, vol.587
, Issue.PART 21
, pp. 5031-5037
-
-
Nadal, A.1
Alonso-Magdalena, P.2
Soriano, S.3
Ropero, A.B.4
Quesada, I.5
-
38
-
-
0034686028
-
Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia
-
DOI 10.1074/jbc.275.20.15399
-
Vasavada RC, et al. Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia. J Biol Chem. 2000;275(20):15399-15406. (Pubitemid 30337270)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.20
, pp. 15399-15406
-
-
Vasavada, R.C.1
Garcia-Ocana, A.2
Zawalich, W.S.3
Sorenson, R.L.4
Dann, P.5
Syed, M.6
Ogren, L.7
Talamantes, F.8
Stewart, A.F.9
-
39
-
-
33745124662
-
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice
-
DOI 10.1073/pnas.0602956103
-
Le May C, et al. Estrogens protect pancreatic betacells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A. 2006;103(24):9232-9237. (Pubitemid 43902561)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.24
, pp. 9232-9237
-
-
Le, M.C.1
Chu, K.2
Hu, M.3
Ortega, C.S.4
Simpson, E.R.5
Korach, K.S.6
Tsai, M.-J.7
Mauvais-Jarvis, F.8
-
40
-
-
77149165088
-
Minireview: Estrogenic protection of beta-cell failure in metabolic diseases
-
Liu S, Mauvais-Jarvis F. Minireview: Estrogenic protection of beta-cell failure in metabolic diseases. Endocrinology. 2010;151(3):859-864.
-
(2010)
Endocrinology
, vol.151
, Issue.3
, pp. 859-864
-
-
Liu, S.1
Mauvais-Jarvis, F.2
-
41
-
-
26844582510
-
Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats
-
Choi SB, Jang JS, Park S. Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats. Endocrinology. 2005;146(11):4786-4794.
-
(2005)
Endocrinology
, vol.146
, Issue.11
, pp. 4786-4794
-
-
Choi, S.B.1
Jang, J.S.2
Park, S.3
-
42
-
-
59649122739
-
Deletion of the G proteincoupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice
-
Martensson UE, et al. Deletion of the G proteincoupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology. 2009;150(2):687-698.
-
(2009)
Endocrinology
, vol.150
, Issue.2
, pp. 687-698
-
-
Martensson, U.E.1
-
43
-
-
79959457594
-
Insulinotropic and antidiabetic effects of 17beta-estradiol and the GPR30 agonist G-1 on human pancreatic islets
-
Kumar R, Balhuizen A, Amisten S, Lundquist I, Salehi A. Insulinotropic and antidiabetic effects of 17beta-estradiol and the GPR30 agonist G-1 on human pancreatic islets. Endocrinology. 2011;152(7):2568-2579.
-
(2011)
Endocrinology
, vol.152
, Issue.7
, pp. 2568-2579
-
-
Kumar, R.1
Balhuizen, A.2
Amisten, S.3
Lundquist, I.4
Salehi, A.5
-
44
-
-
39749097760
-
GPR30: A novel therapeutic target in estrogen-related disease
-
Prossnitz ER, Sklar LA, Oprea TI, Arterburn JB. GPR30: a novel therapeutic target in estrogen-related disease. Trends Pharmacol Sci. 2008;29(3):116-123.
-
(2008)
Trends Pharmacol Sci
, vol.29
, Issue.3
, pp. 116-123
-
-
Prossnitz, E.R.1
Sklar, L.A.2
Oprea, T.I.3
Arterburn, J.B.4
-
45
-
-
79959768665
-
G protein-coupled oestrogen receptor 1 (GPER1)/GPR30: A new player in cardiovascular and metabolic oestrogenic signalling
-
Nilsson BO, Olde B, Leeb-Lundberg LM. G protein-coupled oestrogen receptor 1 (GPER1)/GPR30: a new player in cardiovascular and metabolic oestrogenic signalling. Br J Pharmacol. 2011;163(6):1131-1139.
-
(2011)
Br J Pharmacol
, vol.163
, Issue.6
, pp. 1131-1139
-
-
Nilsson, B.O.1
Olde, B.2
Leeb-Lundberg, L.M.3
-
46
-
-
0036140032
-
Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
-
DOI 10.1210/me.16.1.70
-
Filardo EJ, Quinn JA, Frackelton AR, JrBland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol. 2002;16(1):70-84. (Pubitemid 34044499)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.1
, pp. 70-84
-
-
Filardo, E.J.1
Quinn, J.A.2
Raymond Jr., F.A.3
Bland, K.I.4
-
47
-
-
33646366423
-
Virtual and biomolecular screening converge on a selective agonist for GPR30
-
Bologa CG, et al. Virtual and biomolecular screening converge on a selective agonist for GPR30. Nat Chem Biol. 2006;2(4):207-212.
-
(2006)
Nat Chem Biol
, vol.2
, Issue.4
, pp. 207-212
-
-
Bologa, C.G.1
-
48
-
-
77956373690
-
Beta-cell failure in diet-induced obese mice stratified according to body weight gain: Secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass
-
Peyot ML, et al. Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes. 2010;59(9):2178-2187.
-
(2010)
Diabetes
, vol.59
, Issue.9
, pp. 2178-2187
-
-
Peyot, M.L.1
-
49
-
-
24144496798
-
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes
-
DOI 10.2337/diabetes.54.9.2755
-
Kjorholt C, Akerfeldt MC, Biden TJ, Laybutt DR. Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. Diabetes. 2005;54(9):2755-2763. (Pubitemid 41233599)
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2755-2763
-
-
Kjorholt, C.1
Akerfeldt, M.C.2
Biden, T.J.3
Laybutt, D.R.4
-
50
-
-
2542479899
-
Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
-
DOI 10.1210/en.2004-0015
-
Brubaker PL, Drucker DJ. Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology. 2004;145(6):2653-2659. (Pubitemid 38686211)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2653-2659
-
-
Brubaker, P.L.1
Drucker, D.J.2
-
51
-
-
0032768616
-
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells
-
DOI 10.1007/s001250051238
-
Buteau J, Roduit R, Susini S, Prentki M. Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells. Diabetologia. 1999;42(7):856-864. (Pubitemid 29325077)
-
(1999)
Diabetologia
, vol.42
, Issue.7
, pp. 856-864
-
-
Buteau, J.1
Roduit, R.2
Susini, S.3
Prentki, M.4
-
52
-
-
68049136013
-
Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop
-
Cornu M, Yang JY, Jaccard E, Poussin C, Widmann C, Thorens B. Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. Diabetes. 2009;58(8):1816-1825.
-
(2009)
Diabetes
, vol.58
, Issue.8
, pp. 1816-1825
-
-
Cornu, M.1
Yang, J.Y.2
Jaccard, E.3
Poussin, C.4
Widmann, C.5
Thorens, B.6
-
53
-
-
79551532051
-
Insulin and glucagon regulate pancreatic alpha-cell proliferation
-
Liu Z, et al. Insulin and glucagon regulate pancreatic alpha-cell proliferation. PLoS One. 2011;6(1):e16096.
-
(2011)
PLoS One
, vol.6
, Issue.1
-
-
Liu, Z.1
-
54
-
-
69949168807
-
Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice
-
Wu X, et al. Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice. Diabetologia. 2009;52(10):2130-2141.
-
(2009)
Diabetologia
, vol.52
, Issue.10
, pp. 2130-2141
-
-
Wu, X.1
-
55
-
-
70349774453
-
The transcriptional response of the islet to pregnancy in mice
-
Rieck S, et al. The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol. 2009;23(10):1702-1712.
-
(2009)
Mol Endocrinol
, vol.23
, Issue.10
, pp. 1702-1712
-
-
Rieck, S.1
-
56
-
-
0027439729
-
Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: Implication for placental lactogen regulation of islet function during pregnancy
-
DOI 10.1210/en.132.2.879
-
Brelje TC, et al. Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy. Endocrinology. 1993;132(2):879-887. (Pubitemid 23056153)
-
(1993)
Endocrinology
, vol.132
, Issue.2
, pp. 879-887
-
-
Brelje, T.C.1
Scharp, D.W.2
Lacy, P.E.3
Ogren, L.4
Talamantes, F.5
Robertson, M.6
Friesen, H.G.7
Sorenson, R.L.8
-
57
-
-
84861335162
-
Importance of oestrogen receptors to preserve functional beta-cell mass in diabetes
-
Tiano JP, Mauvais-Jarvis F. Importance of oestrogen receptors to preserve functional beta-cell mass in diabetes. Nat Rev Endocrinol. 2012; 8(6):342-351.
-
(2012)
Nat Rev Endocrinol
, vol.8
, Issue.6
, pp. 342-351
-
-
Tiano, J.P.1
Mauvais-Jarvis, F.2
-
58
-
-
43549095238
-
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30
-
DOI 10.1146/annurev.physiol.70.113006.100518
-
Prossnitz ER, Arterburn JB, Smith HO, Oprea TI, Sklar LA, Hathaway HJ. Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annu Rev Physiol. 2008;70:165-190. (Pubitemid 351738176)
-
(2008)
Annual Review of Physiology
, vol.70
, pp. 165-190
-
-
Prossnitz, E.R.1
Arterburn, J.B.2
Smith, H.O.3
Oprea, T.I.4
Sklar, L.A.5
Hathaway, H.J.6
-
59
-
-
14844343093
-
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
-
DOI 10.1126/science.1106943
-
Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science. 2005;307(5715):1625-1630. (Pubitemid 40354745)
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1625-1630
-
-
Revankar, C.M.1
Cimino, D.F.2
Sklar, L.A.3
Arterburn, J.B.4
Prossnitz, E.R.5
-
60
-
-
70349649964
-
Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival
-
Liu S, et al. Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes. 2009;58(10):2292-2302.
-
(2009)
Diabetes
, vol.58
, Issue.10
, pp. 2292-2302
-
-
Liu, S.1
-
61
-
-
79960977229
-
Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes
-
Tiano JP, et al. Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes. J Clin Invest. 2011;121(8):3331-3342.
-
(2011)
J Clin Invest
, vol.121
, Issue.8
, pp. 3331-3342
-
-
Tiano, J.P.1
-
62
-
-
77954244922
-
A critical review of fundamental controversies in the field of GPR30 research
-
Langer G, et al. A critical review of fundamental controversies in the field of GPR30 research. Steroids. 2010;75(8-9):603-610.
-
(2010)
Steroids
, vol.75
, Issue.8-9
, pp. 603-610
-
-
Langer, G.1
-
63
-
-
81255157471
-
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
-
Ellingsgaard H, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med. 2011;17(11):1481-1489.
-
(2011)
Nat Med
, vol.17
, Issue.11
, pp. 1481-1489
-
-
Ellingsgaard, H.1
-
64
-
-
79951576817
-
Trophic effects of PACAP on pancreatic islets: A mini-review
-
Sakurai Y, Shintani N, Hayata A, Hashimoto H, Baba A. Trophic effects of PACAP on pancreatic islets: a mini-review. J Mol Neurosci. 2011;43(1):3-7.
-
(2011)
J Mol Neurosci
, vol.43
, Issue.1
, pp. 3-7
-
-
Sakurai, Y.1
Shintani, N.2
Hayata, A.3
Hashimoto, H.4
Baba, A.5
-
65
-
-
79953734660
-
Control of pancreatic beta cell regeneration by glucose metabolism
-
Porat S, et al. Control of pancreatic beta cell regeneration by glucose metabolism. Cell Metab. 2011;13(4):440-449.
-
(2011)
Cell Metab
, vol.13
, Issue.4
, pp. 440-449
-
-
Porat, S.1
-
66
-
-
79953752183
-
Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice
-
Levitt HE, et al. Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice. Diabetologia. 2011;54(3):572-582.
-
(2011)
Diabetologia
, vol.54
, Issue.3
, pp. 572-582
-
-
Levitt, H.E.1
-
67
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry RA, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4(2):249-264.
-
(2003)
Biostatistics
, vol.4
, Issue.2
, pp. 249-264
-
-
Irizarry, R.A.1
-
68
-
-
1342288026
-
Affy - Analysis of Affymetrix GeneChip data at the probe level
-
DOI 10.1093/bioinformatics/btg405
-
Gautier L, Cope L, Bolstad BM, Irizarry RA. affy - analysis of Affymetrix GeneChip data at the probe level. Bioinformatics. 2004;20(3):307-315. (Pubitemid 38262761)
-
(2004)
Bioinformatics
, vol.20
, Issue.3
, pp. 307-315
-
-
Gautier, L.1
Cope, L.2
Bolstad, B.M.3
Irizarry, R.A.4
-
69
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Article3
-
Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
70
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
Huang da W, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 2009;37(1):1-13.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.1
, pp. 1-13
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
71
-
-
0034006587
-
+ channel-dependent and -independent glucose-stimulated insulin secretion
-
Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes. 2000;49(3):424-430. (Pubitemid 30131788)
-
(2000)
Diabetes
, vol.49
, Issue.3
, pp. 424-430
-
-
Hohmeier, H.E.1
Mulder, H.2
Chen, G.3
Henkel-Rieger, R.4
Prentki, M.5
Newgard, C.B.6
-
72
-
-
0037390423
-
Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines
-
DOI 10.1210/en.2002-220916
-
Lilla V, et al. Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. Endocrinology. 2003;144(4):1368-1379. (Pubitemid 36428479)
-
(2003)
Endocrinology
, vol.144
, Issue.4
, pp. 1368-1379
-
-
Lilla, V.1
Webb, G.2
Rickenbach, K.3
Maturana, A.4
Steiner, D.F.5
Halban, P.A.6
Irminger, J.-C.7
-
73
-
-
0023224147
-
Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection
-
Gotoh M, et al. Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation. 1987;43(5):725-730. (Pubitemid 17075344)
-
(1987)
Transplantation
, vol.43
, Issue.5
, pp. 725-730
-
-
Gotoh, M.1
Maki, T.2
Satomi, S.3
|