메뉴 건너뛰기




Volumn 57, Issue 2, 2014, Pages 362-365

Are we overestimating the loss of beta cells in type 2 diabetes?

Author keywords

Beta cells; Chromogranin A; Electron microscopy; Glucagon; Insulin; Insulin granules

Indexed keywords

CHROMOGRANIN A; GLUCAGON; GLUCOSE; INSULIN;

EID: 84893710029     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3098-3     Document Type: Article
Times cited : (111)

References (17)
  • 1
    • 84864285795 scopus 로고    scopus 로고
    • Management of hyperglycaemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • 1:STN:280:DC%2BC38rnsV2jsA%3D%3D 22526604 10.1007/s00125-012-2534-0
    • Inzucchi SE, Bergenstal RM, Buse JB et al (2012) Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 55:1577-1596
    • (2012) Diabetologia , vol.55 , pp. 1577-1596
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 2
    • 41849097354 scopus 로고    scopus 로고
    • Beta cell mass in diabetes: A realistic therapeutic target?
    • 1:STN:280:DC%2BD1c3jtF2nsw%3D%3D 18317728 10.1007/s00125-008-0936-9
    • Meier JJ (2008) Beta cell mass in diabetes: a realistic therapeutic target? Diabetologia 51:703-713
    • (2008) Diabetologia , vol.51 , pp. 703-713
    • Meier, J.J.1
  • 3
    • 18644376240 scopus 로고    scopus 로고
    • Type 2 diabetes, insulin secretion and beta-cell mass
    • 15892647 10.2174/1566524053766004
    • Ahrén B (2005) Type 2 diabetes, insulin secretion and beta-cell mass. Curr Mol Med 5:275-286
    • (2005) Curr Mol Med , vol.5 , pp. 275-286
    • Ahrén, B.1
  • 4
    • 44649109566 scopus 로고    scopus 로고
    • Weighing up beta-cell mass in mice and humans: Self-renewal, progenitors or stem cells?
    • 1:CAS:528:DC%2BD1cXmvVKrs7k%3D 18450368 10.1016/j.mce.2008.03.001
    • Hanley NA, Hanley KP, Miettinen PJ, Otonkoski T (2008) Weighing up beta-cell mass in mice and humans: self-renewal, progenitors or stem cells? Mol Cell Endocrinol 288:79-85
    • (2008) Mol Cell Endocrinol , vol.288 , pp. 79-85
    • Hanley, N.A.1    Hanley, K.P.2    Miettinen, P.J.3    Otonkoski, T.4
  • 5
    • 1842844414 scopus 로고    scopus 로고
    • Decreased beta-cell mass in diabetes: Significance, mechanisms and therapeutic implications
    • 1:STN:280:DC%2BD2c7mtVChug%3D%3D 14767595 10.1007/s00125-004-1336-4
    • Donath MY, Halban PA (2004) Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications. Diabetologia 47:581-589
    • (2004) Diabetologia , vol.47 , pp. 581-589
    • Donath, M.Y.1    Halban, P.A.2
  • 6
    • 0037219411 scopus 로고    scopus 로고
    • Beta cell deficit and increased beta cell apoptosis in humans with type 2 diabetes
    • 1:CAS:528:DC%2BD3sXisVaisA%3D%3D 12502499 10.2337/diabetes.52.1.102
    • Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC (2003) Beta cell deficit and increased beta cell apoptosis in humans with type 2 diabetes. Diabetes 52:102-110
    • (2003) Diabetes , vol.52 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 7
    • 75549088122 scopus 로고    scopus 로고
    • Goals of treatment for type 2 diabetes: Beta-cell preservation for glycemic control
    • 1:CAS:528:DC%2BC3cXpvFOhuw%3D%3D 19875548 10.2337/dc09-S306
    • Marchetti P, Lupi R, del Guerra S et al (2009) Goals of treatment for type 2 diabetes: beta-cell preservation for glycemic control. Diabetes Care 32(Suppl 2):S178-S183
    • (2009) Diabetes Care , vol.32 , Issue.SUPPL 2
    • Marchetti, P.1    Lupi, R.2    Del Guerra, S.3
  • 8
    • 84866639915 scopus 로고    scopus 로고
    • Effects of bariatric surgery on glucose homeostasis and type 2 diabetes
    • 1:CAS:528:DC%2BC38XhsVSlur%2FJ 3462491 22885332 10.1053/j.gastro.2012.07. 114
    • Bradley D, Magkos F, Klein S (2012) Effects of bariatric surgery on glucose homeostasis and type 2 diabetes. Gastroenterology 143:897-912
    • (2012) Gastroenterology , vol.143 , pp. 897-912
    • Bradley, D.1    Magkos, F.2    Klein, S.3
  • 9
    • 84866389264 scopus 로고    scopus 로고
    • Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure
    • 1:CAS:528:DC%2BC38XhtlKrsbzI 3445031 22980982 10.1016/j.cell.2012.07.029
    • Talchai C, Xuan S, Lin HV, Sussel L, Accili D (2012) Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure. Cell 150:1223-1234
    • (2012) Cell , vol.150 , pp. 1223-1234
    • Talchai, C.1    Xuan, S.2    Lin, H.V.3    Sussel, L.4    Accili, D.5
  • 10
    • 84862516777 scopus 로고    scopus 로고
    • Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans
    • 1:STN:280:DC%2BC38vhsVCksA%3D%3D 22286529 10.1007/s00125-012-2466-8
    • Meier JJ, Breuer TG, Bonadonna RC et al (2012) Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans. Diabetologia 55:1346-1354
    • (2012) Diabetologia , vol.55 , pp. 1346-1354
    • Meier, J.J.1    Breuer, T.G.2    Bonadonna, R.C.3
  • 11
    • 80052737348 scopus 로고    scopus 로고
    • Histopathology and ex vivo insulin secretion of pancreatic islets in gestational diabetes: A case report
    • 21765242 10.4161/isl.3.5.15940
    • Tancredi M, Marselli L, Lencioni C et al (2011) Histopathology and ex vivo insulin secretion of pancreatic islets in gestational diabetes: a case report. Islets 3:231-233
    • (2011) Islets , vol.3 , pp. 231-233
    • Tancredi, M.1    Marselli, L.2    Lencioni, C.3
  • 12
    • 35848963392 scopus 로고    scopus 로고
    • The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
    • 1:CAS:528:DC%2BD2sXht1Kku7bM 17906960 10.1007/s00125-007-0816-8
    • Marchetti P, Bugliani M, Lupi R et al (2007) The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia 50:2486-2494
    • (2007) Diabetologia , vol.50 , pp. 2486-2494
    • Marchetti, P.1    Bugliani, M.2    Lupi, R.3
  • 13
    • 77955364191 scopus 로고    scopus 로고
    • Gene expression profiles of beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes
    • 2903480 20644627 10.1371/journal.pone.0011499
    • Marselli L, Thorne J, Dahiya S et al (2010) Gene expression profiles of beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS One 5:e11499
    • (2010) PLoS One , vol.5 , pp. 11499
    • Marselli, L.1    Thorne, J.2    Dahiya, S.3
  • 14
    • 81055129681 scopus 로고    scopus 로고
    • Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes
    • 1:CAS:528:DC%2BC3MXhsFynurzO 3216964 22102895 10.1371/journal.pone. 0027445
    • Kilimnik G, Zhao B, Jo J et al (2011) Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes. PLoS One 6:e27445
    • (2011) PLoS One , vol.6 , pp. 27445
    • Kilimnik, G.1    Zhao, B.2    Jo, J.3
  • 15
    • 53549093011 scopus 로고    scopus 로고
    • Pancreatic beta-cell mass in European subjects with type 2 diabetes
    • 10.1111/j.1463-1326.2008.00969.x
    • Rahier J, Guiot Y, Goebbels RM, Sempoux C, Henquin JC (2008) Pancreatic beta-cell mass in European subjects with type 2 diabetes. Diab Obes Metab 10(Suppl 4):32-34
    • (2008) Diab Obes Metab , vol.10 , Issue.SUPPL 4 , pp. 32-34
    • Rahier, J.1    Guiot, Y.2    Goebbels, R.M.3    Sempoux, C.4    Henquin, J.C.5
  • 16
    • 77950290798 scopus 로고    scopus 로고
    • Beta cell mass dynamics and islet cell plasticity in human type 2 diabetes
    • 1:CAS:528:DC%2BC3cXks1Cmtr0%3D 20176718 10.1210/en.2009-1277
    • Hanley AC, Austin E, Assouline-Thomas B et al (2010) Beta cell mass dynamics and islet cell plasticity in human type 2 diabetes. Endocrinology 151:1462-1472
    • (2010) Endocrinology , vol.151 , pp. 1462-1472
    • Hanley, A.C.1    Austin, E.2    Assouline-Thomas, B.3
  • 17
    • 10744222060 scopus 로고    scopus 로고
    • Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects
    • 1:CAS:528:DC%2BD2cXhvFelu78%3D 14988246 10.2337/diabetes.53.3.624
    • Deng S, Vatamaniuk M, Huang X et al (2004) Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects. Diabetes 53:624-632
    • (2004) Diabetes , vol.53 , pp. 624-632
    • Deng, S.1    Vatamaniuk, M.2    Huang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.