Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets

Diabetologia

Volumn 54, Issue 9, 2011, Pages 2337-2346

  Favre, D ^a,b   Niederhauser, G ^a,b   Fahmi, D ^a,b   Plaisance, V ^a,b   Brajkovic, S ^a,b   Beeler, N ^a,b   Allagnat, F ^a   Haefliger, J A ^a   Regazzi, R ^b   Waeber, G ^a   Abderrahmani, A ^a,b,c  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIV LILLE   (France)

Author keywords

Antioxidant; Apoptosis; Diabetes; HDL; ICER; Insulin; Oxidative stress; Oxidised LDL; Pancreatic beta cells

Indexed keywords

ACETYLCYSTEINE; CYCLIC AMP; GUANOSINE TRIPHOSPHATASE; HIGH DENSITY LIPOPROTEIN; HYDROGEN PEROXIDE; INDUCIBLE CYCLIC AMP EARLY REPRESSOR; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; RAB PROTEIN; RAB27A PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL FUNCTION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HYDROLYSIS; INSULIN RELEASE; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT MODULATOR; HUMANS; HYDROGEN PEROXIDE; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; LIPOPROTEINS, LDL; MALE; MODELS, ANIMAL; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING;

EID: 80054707772     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2165-x     Document Type: Article

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