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Volumn 8, Issue 1, 2013, Pages

Reduction of Connexin36 Content by ICER-1 Contributes to Insulin-Secreting Cells Apoptosis Induced by Oxidized LDL Particles

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 36; INDUCIBLE CYCLIC AMP EARLY REPRESSOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; PERILIPIN; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84873844411     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055198     Document Type: Article
Times cited : (17)

References (51)
  • 1
    • 77951926420 scopus 로고    scopus 로고
    • Etiology of type 1 diabetes
    • Todd JA, (2010) Etiology of type 1 diabetes. Immunity 32: 457-467.
    • (2010) Immunity , vol.32 , pp. 457-467
    • Todd, J.A.1
  • 2
    • 34249682591 scopus 로고    scopus 로고
    • beta-cell failure in diabetes and preservation by clinical treatment
    • Wajchenberg BL, (2007) beta-cell failure in diabetes and preservation by clinical treatment. Endocr Rev 28: 187-218.
    • (2007) Endocr Rev , vol.28 , pp. 187-218
    • Wajchenberg, B.L.1
  • 3
    • 80054765899 scopus 로고    scopus 로고
    • Connexins: key mediators of endocrine function
    • Bosco D, Haefliger JA, Meda P, (2011) Connexins: key mediators of endocrine function. Physiol Rev 91: 1393-1445.
    • (2011) Physiol Rev , vol.91 , pp. 1393-1445
    • Bosco, D.1    Haefliger, J.A.2    Meda, P.3
  • 4
    • 41949138132 scopus 로고    scopus 로고
    • ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells
    • Allagnat F, Alonso F, Martin D, Abderrahmani A, Waeber G, et al. (2008) ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J Biol Chem 283: 5226-5234.
    • (2008) J Biol Chem , vol.283 , pp. 5226-5234
    • Allagnat, F.1    Alonso, F.2    Martin, D.3    Abderrahmani, A.4    Waeber, G.5
  • 5
    • 0141844506 scopus 로고    scopus 로고
    • Connexin-36 contributes to control function of insulin-producing cells
    • Le Gurun S, Martin D, Formenton A, Maechler P, Caille D, et al. (2003) Connexin-36 contributes to control function of insulin-producing cells. J Biol Chem 278: 37690-37697.
    • (2003) J Biol Chem , vol.278 , pp. 37690-37697
    • Le Gurun, S.1    Martin, D.2    Formenton, A.3    Maechler, P.4    Caille, D.5
  • 7
  • 9
    • 12944299284 scopus 로고    scopus 로고
    • Low-density lipoprotein size and subclasses are markers of clinically apparent and non-apparent atherosclerosis in type 2 diabetes
    • Berneis K, Jeanneret C, Muser J, Felix B, Miserez AR, (2005) Low-density lipoprotein size and subclasses are markers of clinically apparent and non-apparent atherosclerosis in type 2 diabetes. Metabolism 54: 227-234.
    • (2005) Metabolism , vol.54 , pp. 227-234
    • Berneis, K.1    Jeanneret, C.2    Muser, J.3    Felix, B.4    Miserez, A.R.5
  • 10
    • 33645872999 scopus 로고    scopus 로고
    • Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander?
    • Heinecke JW, (2006) Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander? J Exp Med 203: 813-816.
    • (2006) J Exp Med , vol.203 , pp. 813-816
    • Heinecke, J.W.1
  • 11
    • 2642526387 scopus 로고    scopus 로고
    • High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease
    • Rohrer L, Hersberger M, von Eckardstein A, (2004) High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease. Curr Opin Lipidol 15: 269-278.
    • (2004) Curr Opin Lipidol , vol.15 , pp. 269-278
    • Rohrer, L.1    Hersberger, M.2    von Eckardstein, A.3
  • 12
    • 14244251463 scopus 로고    scopus 로고
    • Oxidation, lipoproteins, and atherosclerosis: which is wrong, the antioxidants or the theory?
    • Williams KJ, Fisher EA, (2005) Oxidation, lipoproteins, and atherosclerosis: which is wrong, the antioxidants or the theory? Curr Opin Clin Nutr Metab Care 8: 139-146.
    • (2005) Curr Opin Clin Nutr Metab Care , vol.8 , pp. 139-146
    • Williams, K.J.1    Fisher, E.A.2
  • 13
    • 77956181479 scopus 로고    scopus 로고
    • Association of macroalbuminuria with oxidized LDL and TGF-beta in type 2 diabetic patients: a case-control study
    • Nakhjavani M, Esteghamati A, Khalilzadeh O, Asgarani F, Mansournia N, et al. (2010) Association of macroalbuminuria with oxidized LDL and TGF-beta in type 2 diabetic patients: a case-control study. Int Urol Nephrol 42: 487-492.
    • (2010) Int Urol Nephrol , vol.42 , pp. 487-492
    • Nakhjavani, M.1    Esteghamati, A.2    Khalilzadeh, O.3    Asgarani, F.4    Mansournia, N.5
  • 14
    • 77953289382 scopus 로고    scopus 로고
    • Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol
    • Nakhjavani M, Khalilzadeh O, Khajeali L, Esteghamati A, Morteza A, et al. (2010) Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol. Lipids 45: 321-327.
    • (2010) Lipids , vol.45 , pp. 321-327
    • Nakhjavani, M.1    Khalilzadeh, O.2    Khajeali, L.3    Esteghamati, A.4    Morteza, A.5
  • 15
    • 0041668083 scopus 로고    scopus 로고
    • LDL-cholesterol, HDL-cholesterol or triglycerides-which is the culprit?
    • Taskinen MR, (2003) LDL-cholesterol, HDL-cholesterol or triglycerides-which is the culprit? Diabetes Res Clin Pract 61Suppl 1: S19-26.
    • (2003) Diabetes Res Clin Pract , vol.61
    • Taskinen, M.R.1
  • 16
    • 0038381515 scopus 로고    scopus 로고
    • Insulin-secreting beta-cell dysfunction induced by human lipoproteins
    • Roehrich ME, Mooser V, Lenain V, Herz J, Nimpf J, et al. (2003) Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem 278: 18368-18375.
    • (2003) J Biol Chem , vol.278 , pp. 18368-18375
    • Roehrich, M.E.1    Mooser, V.2    Lenain, V.3    Herz, J.4    Nimpf, J.5
  • 17
    • 0036721312 scopus 로고    scopus 로고
    • Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification
    • Cnop M, Hannaert JC, Grupping AY, Pipeleers DG, (2002) Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification. Endocrinology 143: 3449-3453.
    • (2002) Endocrinology , vol.143 , pp. 3449-3453
    • Cnop, M.1    Hannaert, J.C.2    Grupping, A.Y.3    Pipeleers, D.G.4
  • 18
    • 34247866358 scopus 로고    scopus 로고
    • Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells
    • Abderrahmani A, Niederhauser G, Favre D, Abdelli S, Ferdaoussi M, et al. (2007) Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells. Diabetologia 50: 1304-1314.
    • (2007) Diabetologia , vol.50 , pp. 1304-1314
    • Abderrahmani, A.1    Niederhauser, G.2    Favre, D.3    Abdelli, S.4    Ferdaoussi, M.5
  • 19
    • 80054707772 scopus 로고    scopus 로고
    • Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets
    • Favre D, Niederhauser G, Fahmi D, Plaisance V, Brajkovic S, et al. (2011) Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets. Diabetologia 54: 2337-2346.
    • (2011) Diabetologia , vol.54 , pp. 2337-2346
    • Favre, D.1    Niederhauser, G.2    Fahmi, D.3    Plaisance, V.4    Brajkovic, S.5
  • 20
    • 77649098985 scopus 로고    scopus 로고
    • The influence of major dietary fatty acids on insulin secretion and action
    • Lopez S, Bermudez B, Abia R, Muriana FJ, (2010) The influence of major dietary fatty acids on insulin secretion and action. Curr Opin Lipidol 21: 15-20.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 15-20
    • Lopez, S.1    Bermudez, B.2    Abia, R.3    Muriana, F.J.4
  • 21
    • 78751640180 scopus 로고    scopus 로고
    • Possible contributions of lipoproteins and cholesterol to the pathogenesis of diabetes mellitus type 2
    • von Eckardstein A, Sibler RA, (2011) Possible contributions of lipoproteins and cholesterol to the pathogenesis of diabetes mellitus type 2. Curr Opin Lipidol 22: 26-32.
    • (2011) Curr Opin Lipidol , vol.22 , pp. 26-32
    • von Eckardstein, A.1    Sibler, R.A.2
  • 23
    • 33845406233 scopus 로고    scopus 로고
    • New insights into the vascular mechanisms underlying the beneficial effect of swimming training on the endothelial vasodilator function in apolipoprotein E-deficient mice
    • Pellegrin M, Berthelot A, Houdayer C, Gaume V, Deckert V, et al. (2007) New insights into the vascular mechanisms underlying the beneficial effect of swimming training on the endothelial vasodilator function in apolipoprotein E-deficient mice. Atherosclerosis 190: 35-42.
    • (2007) Atherosclerosis , vol.190 , pp. 35-42
    • Pellegrin, M.1    Berthelot, A.2    Houdayer, C.3    Gaume, V.4    Deckert, V.5
  • 24
    • 81055138804 scopus 로고    scopus 로고
    • Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging
    • Meyrelles SS, Peotta VA, Pereira TM, Vasquez EC, (2011) Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging. Lipids in health and disease 10: 211.
    • (2011) Lipids in Health and Disease , vol.10 , pp. 211
    • Meyrelles, S.S.1    Peotta, V.A.2    Pereira, T.M.3    Vasquez, E.C.4
  • 25
    • 0842291578 scopus 로고    scopus 로고
    • Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells
    • Merglen A, Theander S, Rubi B, Chaffard G, Wollheim CB, et al. (2004) Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology 145: 667-678.
    • (2004) Endocrinology , vol.145 , pp. 667-678
    • Merglen, A.1    Theander, S.2    Rubi, B.3    Chaffard, G.4    Wollheim, C.B.5
  • 26
    • 0037390423 scopus 로고    scopus 로고
    • Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines
    • Lilla V, Webb G, Rickenbach K, Maturana A, Steiner DF, et al. (2003) Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. Endocrinology 144: 1368-1379.
    • (2003) Endocrinology , vol.144 , pp. 1368-1379
    • Lilla, V.1    Webb, G.2    Rickenbach, K.3    Maturana, A.4    Steiner, D.F.5
  • 27
    • 0026793195 scopus 로고
    • Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O
    • Ramirez-Zacarias JL, Castro-Munozledo F, Kuri-Harcuch W, (1992) Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry. 97: 493-497.
    • (1992) Histochemistry , vol.97 , pp. 493-497
    • Ramirez-Zacarias, J.L.1    Castro-Munozledo, F.2    Kuri-Harcuch, W.3
  • 28
    • 0035882492 scopus 로고    scopus 로고
    • Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36
    • Guldenagel M, Ammermuller J, Feigenspan A, Teubner B, Degen J, et al. (2001) Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36. J Neurosci 21: 6036-6044.
    • (2001) J Neurosci , vol.21 , pp. 6036-6044
    • Guldenagel, M.1    Ammermuller, J.2    Feigenspan, A.3    Teubner, B.4    Degen, J.5
  • 29
    • 71449112615 scopus 로고    scopus 로고
    • Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes
    • Pellegrin M, Alonso F, Aubert JF, Bouzourene K, Braunersreuther V, et al. (2009) Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes. Hypertension 53: 782-789.
    • (2009) Hypertension , vol.53 , pp. 782-789
    • Pellegrin, M.1    Alonso, F.2    Aubert, J.F.3    Bouzourene, K.4    Braunersreuther, V.5
  • 30
    • 78651303018 scopus 로고    scopus 로고
    • Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to beta-cell apoptosis
    • Allagnat F, Cunha D, Moore F, Vanderwinden JM, Eizirik DL, et al. (2011) Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to beta-cell apoptosis. Cell Death Differ 18: 328-337.
    • (2011) Cell Death Differ , vol.18 , pp. 328-337
    • Allagnat, F.1    Cunha, D.2    Moore, F.3    Vanderwinden, J.M.4    Eizirik, D.L.5
  • 31
    • 0027741257 scopus 로고
    • Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor
    • Molina CA, Foulkes NS, Lalli E, Sassone-Corsi P, (1993) Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell 75: 875-886.
    • (1993) Cell , vol.75 , pp. 875-886
    • Molina, C.A.1    Foulkes, N.S.2    Lalli, E.3    Sassone-Corsi, P.4
  • 32
    • 33644859688 scopus 로고    scopus 로고
    • ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis
    • Abderrahmani A, Cheviet S, Ferdaoussi M, Coppola T, Waeber G, et al. (2006) ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis. EMBO J 25: 977-986.
    • (2006) EMBO J , vol.25 , pp. 977-986
    • Abderrahmani, A.1    Cheviet, S.2    Ferdaoussi, M.3    Coppola, T.4    Waeber, G.5
  • 33
    • 66649132790 scopus 로고    scopus 로고
    • PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis
    • Moore F, Colli ML, Cnop M, Esteve MI, Cardozo AK, et al. (2009) PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis. Diabetes 58: 1283-1291.
    • (2009) Diabetes , vol.58 , pp. 1283-1291
    • Moore, F.1    Colli, M.L.2    Cnop, M.3    Esteve, M.I.4    Cardozo, A.K.5
  • 34
    • 84870988528 scopus 로고    scopus 로고
    • C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in beta-cells
    • Allagnat F, Fukaya M, Nogueira TC, Delaroche D, Welsh N, et al. (2012) C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in beta-cells. Cell Death Differ.
    • (2012) Cell Death Differ
    • Allagnat, F.1    Fukaya, M.2    Nogueira, T.C.3    Delaroche, D.4    Welsh, N.5
  • 35
    • 48149101799 scopus 로고    scopus 로고
    • Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells
    • Martin D, Allagnat F, Chaffard G, Caille D, Fukuda M, et al. (2008) Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells. Diabetologia 51: 1429-1439.
    • (2008) Diabetologia , vol.51 , pp. 1429-1439
    • Martin, D.1    Allagnat, F.2    Chaffard, G.3    Caille, D.4    Fukuda, M.5
  • 36
    • 19944432792 scopus 로고    scopus 로고
    • Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells
    • Cardozo AK, Ortis F, Storling J, Feng YM, Rasschaert J, et al. (2005) Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells. Diabetes 54: 452-461.
    • (2005) Diabetes , vol.54 , pp. 452-461
    • Cardozo, A.K.1    Ortis, F.2    Storling, J.3    Feng, Y.M.4    Rasschaert, J.5
  • 37
    • 80052846979 scopus 로고    scopus 로고
    • Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, beta-cell proliferation, and mass
    • Nguidjoe E, Sokolow S, Bigabwa S, Pachera N, D'Amico E, et al. (2011) Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, beta-cell proliferation, and mass. Diabetes 60: 2076-2085.
    • (2011) Diabetes , vol.60 , pp. 2076-2085
    • Nguidjoe, E.1    Sokolow, S.2    Bigabwa, S.3    Pachera, N.4    D'Amico, E.5
  • 39
    • 0032478347 scopus 로고    scopus 로고
    • Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis
    • Hofker MH, van Vlijmen BJ, Havekes LM, (1998) Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis. Atherosclerosis 137: 1-11.
    • (1998) Atherosclerosis , vol.137 , pp. 1-11
    • Hofker, M.H.1    van Vlijmen, B.J.2    Havekes, L.M.3
  • 40
    • 42149113411 scopus 로고    scopus 로고
    • Lipoprotein size and susceptibility to atherosclerosis-insights from genetically modified mouse models
    • Veniant MM, Beigneux AP, Bensadoun A, Fong LG, Young SG, (2008) Lipoprotein size and susceptibility to atherosclerosis-insights from genetically modified mouse models. Curr Drug Targets 9: 174-189.
    • (2008) Curr Drug Targets , vol.9 , pp. 174-189
    • Veniant, M.M.1    Beigneux, A.P.2    Bensadoun, A.3    Fong, L.G.4    Young, S.G.5
  • 41
    • 2942520978 scopus 로고    scopus 로고
    • Atherosclerosis in the apolipoprotein-E-deficient mouse: a decade of progress
    • Meir KS, Leitersdorf E, (2004) Atherosclerosis in the apolipoprotein-E-deficient mouse: a decade of progress. Arterioscler Thromb Vasc Biol 24: 1006-1014.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1006-1014
    • Meir, K.S.1    Leitersdorf, E.2
  • 42
  • 43
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R, Keaney JF Jr, (2004) Role of oxidative modifications in atherosclerosis. Physiol Rev 84: 1381-1478.
    • (2004) Physiol Rev , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney Jr., J.F.2
  • 44
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang SH, Reddick RL, Piedrahita JA, Maeda N, (1992) Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 258: 468-471.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 45
    • 0037389415 scopus 로고    scopus 로고
    • HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells
    • Robbesyn F, Garcia V, Auge N, Vieira O, Frisach MF, et al. (2003) HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells. Faseb J 17: 743-745.
    • (2003) Faseb J , vol.17 , pp. 743-745
    • Robbesyn, F.1    Garcia, V.2    Auge, N.3    Vieira, O.4    Frisach, M.F.5
  • 47
    • 38149133304 scopus 로고    scopus 로고
    • Genetics and molecular biology: HDLs and their multiple ways to protect cells
    • Petremand J, Abderrahmani A, Widmann C, (2008) Genetics and molecular biology: HDLs and their multiple ways to protect cells. Curr Opin Lipidol 19: 95-97.
    • (2008) Curr Opin Lipidol , vol.19 , pp. 95-97
    • Petremand, J.1    Abderrahmani, A.2    Widmann, C.3
  • 48
    • 84860592286 scopus 로고    scopus 로고
    • HDLs protect pancreatic beta-cells against ER stress by restoring protein folding and trafficking
    • Petremand J, Puyal J, Chatton JY, Duprez J, Allagnat F, et al. (2012) HDLs protect pancreatic beta-cells against ER stress by restoring protein folding and trafficking. Diabetes 61: 1100-1111.
    • (2012) Diabetes , vol.61 , pp. 1100-1111
    • Petremand, J.1    Puyal, J.2    Chatton, J.Y.3    Duprez, J.4    Allagnat, F.5
  • 49
    • 0042922453 scopus 로고    scopus 로고
    • Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death
    • El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, et al. (2003) Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology 144: 4154-4163.
    • (2003) Endocrinology , vol.144 , pp. 4154-4163
    • El-Assaad, W.1    Buteau, J.2    Peyot, M.L.3    Nolan, C.4    Roduit, R.5
  • 50
    • 36649015243 scopus 로고    scopus 로고
    • Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
    • Brasaemle DL, (2007) Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J Lipid Res 48: 2547-2559.
    • (2007) J Lipid Res , vol.48 , pp. 2547-2559
    • Brasaemle, D.L.1
  • 51
    • 79955601028 scopus 로고    scopus 로고
    • Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
    • Pike LS, Smift AL, Croteau NJ, Ferrick DA, Wu M, (2011) Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. Biochim Biophys Acta 1807: 726-734.
    • (2011) Biochim Biophys Acta , vol.1807 , pp. 726-734
    • Pike, L.S.1    Smift, A.L.2    Croteau, N.J.3    Ferrick, D.A.4    Wu, M.5


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