The Rad50 hook domain regulates DNA damage signaling and tumorigenesis

Genes and Development

Volumn 28, Issue 5, 2014, Pages 451-462

  Roset, Ramon ^a   Inagaki, Akiko ^a   Hohl, Marcel ^a   Brenet, Fabienne ^b   Lafrance Vanasse, Julien ^c   Lange, Julian ^a   Scandura, Joseph M ^b   Tainer, John A ^c   Keeney, Scott ^a,d   Petrini, John H J ^a,d  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d Weill Graduate School of Medical Sciences of Cornell University   (United States)

Author keywords

ATM; Double strand breaks; Mre11 complex; Rad50

Indexed keywords

ATM PROTEIN; MRE11 PROTEIN; RAD50 PROTEIN; ZINC ION;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA REPAIR; GERM CELL; HEMATOPOIETIC CELL; HETEROZYGOTE; HOMEOSTASIS; HYDROCEPHALUS; LIVER CARCINOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL;

ATM; DOUBLE-STRAND BREAKS; MRE11 COMPLEX; RAD50;

ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CARCINOGENESIS; CELL CYCLE CHECKPOINTS; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; GERM CELLS; MICE; MUTATION; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 84896820650     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.236745.113     Document Type: Article

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