메뉴 건너뛰기




Volumn 210, Issue 3, 2013, Pages 623-639

Tgfβ restores hematopoietic homeostasis after myelosuppressive chemotherapy

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1C; FLUOROURACIL; HEMOGLOBIN; TRANSFORMING GROWTH FACTOR BETA; ANTINEOPLASTIC AGENT; CDKN1C PROTEIN, MOUSE;

EID: 84877607466     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121610     Document Type: Article
Times cited : (76)

References (71)
  • 1
    • 0037439630 scopus 로고    scopus 로고
    • Making sense of latent TGFbeta activation
    • Annes, J.P., J.S. Munger, and D.B. Rifkin. 2003. Making sense of latent TGFbeta activation. J. Cell Sci. 116:217-224. http://dx.doi.org/10.1242/jcs.00229
    • (2003) J. Cell Sci. , vol.116 , pp. 217-224
    • Annes, J.P.1    Munger, J.S.2    Rifkin, D.B.3
  • 2
    • 0029736871 scopus 로고    scopus 로고
    • Redox-mediated activation of latent transforming growth factor-beta 1
    • Barcellos-Hoff, M.H., and T.A. Dix. 1996. Redox-mediated activation of latent transforming growth factor-beta 1. Mol. Endocrinol. 10:1077-1083. http://dx.doi.org/10.1210/me.10.9.1077
    • (1996) Mol. Endocrinol , vol.10 , pp. 1077-1083
    • Barcellos-Hoff, M.H.1    Dix, T.A.2
  • 3
    • 0033996341 scopus 로고    scopus 로고
    • TGF-(beta)1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation
    • Batard, P., M.N. Monier, N. Fortunel, K. Ducos, P. Sansilvestri-Morel, T. Phan, A. Hatzfeld, and J.A. Hatzfeld. 2000. TGF-(beta)1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation. J. Cell Sci. 113:383-390.
    • (2000) J. Cell Sci. , vol.113 , pp. 383-390
    • Batard, P.1    Monier, M.N.2    Fortunel, N.3    Ducos, K.4    Sansilvestri-Morel, P.5    Phan, T.6    Hatzfeld, A.7    Hatzfeld, J.A.8
  • 4
    • 34248185926 scopus 로고    scopus 로고
    • Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression
    • Biswas, S., M. Guix, C. Rinehart, T.C. Dugger, A. Chytil, H.L. Moses, M.L. Freeman, and C.L. Arteaga. 2007. Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. J. Clin. Invest. 117:1305-1313. http://dx.doi.org/10.1172/JCI30740
    • (2007) J. Clin. Invest. , vol.117 , pp. 1305-1313
    • Biswas, S.1    Guix, M.2    Rinehart, C.3    Dugger, T.C.4    Chytil, A.5    Moses, H.L.6    Freeman, M.L.7    Arteaga, C.L.8
  • 5
    • 80052445124 scopus 로고    scopus 로고
    • The role of Smad signaling in hematopoiesis and translational hematology
    • Blank, U., and S. Karlsson. 2011. The role of Smad signaling in hematopoiesis and translational hematology. Leukemia. 25:1379-1388. http://dx.doi.org/10.1038/leu.2011.95
    • (2011) Leukemia. , vol.25 , pp. 1379-1388
    • Blank, U.1    Karlsson, S.2
  • 7
    • 0030914867 scopus 로고    scopus 로고
    • Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
    • Bradford, G.B., B. Williams, R. Rossi, and I. Bertoncello. 1997. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp. Hematol. 25:445-453.
    • (1997) Exp. Hematol. , vol.25 , pp. 445-453
    • Bradford, G.B.1    Williams, B.2    Rossi, R.3    Bertoncello, I.4
  • 9
    • 0033694302 scopus 로고    scopus 로고
    • Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
    • Cheng, T., N. Rodrigues, D. Dombkowski, S. Stier, and D.T. Scadden. 2000a. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat. Med. 6:1235-1240. http://dx.doi.org/19.1938/81335
    • (2000) Nat. Med. , vol.6 , pp. 1235-1240
    • Cheng, T.1    Rodrigues, N.2    Dombkowski, D.3    Stier, S.4    Scadden, D.T.5
  • 10
    • 0034629129 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence maintained by p21cip1/waf1
    • Cheng, T., N. Rodrigues, H. Shen, Y. Yang, D. Dombkowski, M. Sykes, and D.T. Scadden. 2000b. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science. 287:1804-1808. http://dx.doi.org/19.1126/science.287.5459.1804
    • (2000) Science. , vol.287 , pp. 1804-1808
    • Cheng, T.1    Rodrigues, N.2    Shen, H.3    Yang, Y.4    Dombkowski, D.5    Sykes, M.6    Scadden, D.T.7
  • 11
    • 0035895046 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21(Cip1/Waf1) or p27(Kip1)
    • Cheng, T., H. Shen, N. Rodrigues, S. Stier, and D.T. Scadden. 2001. Transforming growth factor beta 1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21(Cip1/Waf1) or p27(Kip1). Blood. 98:3643-3649. http://dx.doi.org/19.1182/blood.V98.13.3643
    • (2001) Blood. , vol.98 , pp. 3643-3649
    • Cheng, T.1    Shen, H.2    Rodrigues, N.3    Stier, S.4    Scadden, D.T.5
  • 12
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier, S.H., S.J. Morrison, X. Liao, and I.L. Weissman. 1999. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc. Natl. Acad. Sci. USA. 96:3120-3125. http://dx.doi.org/19.1973/pnas.96.6.3120
    • (1999) Proc. Natl. Acad. Sci. USA. , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 14
    • 84863011896 scopus 로고    scopus 로고
    • Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
    • Csaszar, E., D.C. Kirouac, M. Yu, W. Wang, W. Qiao, M.P. Cooke, A.E. Boitano, C. Ito, and P.W. Zandstra. 2012. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell. 19:218-229. http://dx.doi.org/19.1916/j.stem.2012.01.003
    • (2012) Cell Stem Cell. , vol.19 , pp. 218-229
    • Csaszar, E.1    Kirouac, D.C.2    Yu, M.3    Wang, W.4    Qiao, W.5    Cooke, M.P.6    Boitano, A.E.7    Ito, C.8    Zandstra, P.W.9
  • 15
    • 0029074681 scopus 로고
    • Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice
    • Dickson, M.C., J.S. Martin, F.M. Cousins, A.B. Kulkarni, S. Karlsson, and R.J. Akhurst. 1995. Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development. 121: 1845-1854.
    • (1995) Development. , vol.121 , pp. 1845-1854
    • Dickson, M.C.1    Martin, J.S.2    Cousins, F.M.3    Kulkarni, A.B.4    Karlsson, S.5    Akhurst, R.J.6
  • 16
    • 79952724283 scopus 로고    scopus 로고
    • The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in
    • Ehninger, A., and A. Trumpp. 2011. The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in. J. Exp. Med. 208: 421-428. http://dx.doi.org/19.1984/jem.20119132
    • (2011) J. Exp. Med. , vol.208 , pp. 421-428
    • Ehninger, A.1    Trumpp, A.2
  • 17
    • 0034585151 scopus 로고    scopus 로고
    • Specific dose-response effects of TGF-beta1 on developmentally distinct hematopoietic stem/progenitor cells from human umbilical cord blood
    • Fortunel, N., J. Hatzfeld, L. Aoustin, P. Batard, K. Ducos, M.N. Monier, A. Charpentier, and A. Hatzfeld. 2000a. Specific dose-response effects of TGF-beta1 on developmentally distinct hematopoietic stem/progenitor cells from human umbilical cord blood. Hematol. J. 1:126-135. http://dx.doi.org/19.1938/sj.thj.6200021
    • (2000) Hematol. J. , vol.1 , pp. 126-135
    • Fortunel, N.1    Hatzfeld, J.2    Aoustin, L.3    Batard, P.4    Ducos, K.5    Monier, M.N.6    Charpentier, A.7    Hatzfeld, A.8
  • 18
    • 0034665777 scopus 로고    scopus 로고
    • Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis
    • Fortunel, N.O., A. Hatzfeld, and J.A. Hatzfeld. 2000b. Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis. Blood. 96:2022-2036.
    • (2000) Blood. , vol.96 , pp. 2022-2036
    • Fortunel, N.O.1    Hatzfeld, A.2    Hatzfeld, J.A.3
  • 19
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik, L., and R.A. Flavell. 2000. Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity. 12:171-181. http://dx.doi.org/19.1916/S1974-7613(00)80170-3
    • (2000) Immunity. , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 20
    • 18444389451 scopus 로고    scopus 로고
    • Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
    • Heissig, B., K. Hattori, S. Dias, M. Friedrich, B. Ferris, N.R. Hackett, R.G. Crystal, P. Besmer, D. Lyden, M.A. Moore, et al. 2002. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell. 199:625-637. http://dx.doi.org/19.1916/S0092-8674(02)00754-7
    • (2002) Cell. , vol.199 , pp. 625-637
    • Heissig, B.1    Hattori, K.2    Dias, S.3    Friedrich, M.4    Ferris, B.5    Hackett, N.R.6    Crystal, R.G.7    Besmer, P.8    Lyden, D.9    Moore, M.A.10
  • 21
    • 84857890422 scopus 로고    scopus 로고
    • Modulation of noncanonical TGF-β signaling preventscleft palate in Tgfbr2 mutant mice
    • Iwata, J.-I., J.G. Hacia, A. Suzuki, P.A. Sanchez-Lara, M. Urata, and Y. Chai. 2012. Modulation of noncanonical TGF-β signaling preventscleft palate in Tgfbr2 mutant mice. J. Clin. Invest. 122:873-885. http://dx.doi.org/19.1172/JCI61498
    • (2012) J. Clin. Invest. , vol.122 , pp. 873-885
    • Iwata, J.-I.1    Hacia, J.G.2    Suzuki, A.3    Sanchez-Lara, P.A.4    Urata, M.5    Chai, Y.6
  • 23
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel, M.J., O.H. Yilmaz, T. Iwashita, O.H. Yilmaz, C. Terhorst, and S.J. Morrison. 2005. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 121:1199-1121. http://dx.doi.org/19.1916/j.cell.2005.05.026
    • (2005) Cell. , vol.121 , pp. 1199-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 25
    • 22144473344 scopus 로고    scopus 로고
    • Tie2 activation contributes to hemangiogenic regeneration after myelosuppression
    • Kopp, H.G., S.T. Avecilla, A.T. Hooper, S.V. Shmelkov, C.A. Ramos, F. Zhang, and S. Rafii. 2005. Tie2 activation contributes to hemangiogenic regeneration after myelosuppression. Blood. 196:505-513. http://dx.doi.org/19.1182/blood-2004-11-4269
    • (2005) Blood. , vol.196 , pp. 505-513
    • Kopp, H.G.1    Avecilla, S.T.2    Hooper, A.T.3    Shmelkov, S.V.4    Ramos, C.A.5    Zhang, F.6    Rafii, S.7
  • 26
    • 0036754547 scopus 로고    scopus 로고
    • Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells
    • Lapidot, T., and I. Petit. 2002. Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp. Hematol. 30:973-981. http://dx.doi.org/19.1916/S0301-472X(02)00883-4
    • (2002) Exp. Hematol. , vol.30 , pp. 973-981
    • Lapidot, T.1    Petit, I.2
  • 28
    • 0142245613 scopus 로고    scopus 로고
    • TGF-beta signalingdeficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro
    • Larsson, J., U. Blank, H. Helgadottir, J.M. Björnsson, M. Ehinger, M.J. Goumans, X. Fan, P. Levéen, and S. Karlsson. 2003. TGF-beta signalingdeficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro. Blood. 192:3129-3135. http://dx.doi.org/19.1182/blood-2003-04-1300
    • (2003) Blood. , vol.192 , pp. 3129-3135
    • Larsson, J.1    Blank, U.2    Helgadottir, H.3    Björnsson, J.M.4    Ehinger, M.5    Goumans, M.J.6    Fan, X.7    Levéen, P.8    Karlsson, S.9
  • 29
    • 17844384518 scopus 로고    scopus 로고
    • Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-beta signaling in vivo
    • Larsson, J., U. Blank, J. Klintman, M. Magnusson, and S. Karlsson. 2005. Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-beta signaling in vivo. Exp. Hematol. 33:592-596. http://dx.doi.org/19.1916/j.exphem.2005.02.003
    • (2005) Exp. Hematol. , vol.33 , pp. 592-596
    • Larsson, J.1    Blank, U.2    Klintman, J.3    Magnusson, M.4    Karlsson, S.5
  • 31
    • 0037100520 scopus 로고    scopus 로고
    • Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable
    • Levéen, P., J. Larsson, M. Ehinger, C.M. Cilio, M. Sundler, L.J. Sjöstrand, R. Holmdahl, and S. Karlsson. 2002. Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. Blood. 190:560-568. http://dx.doi.org/19.1182/blood.V190.2.560
    • (2002) Blood. , vol.190 , pp. 560-568
    • Levéen, P.1    Larsson, J.2    Ehinger, M.3    Cilio, C.M.4    Sundler, M.5    Sjöstrand, L.J.6    Holmdahl, R.7    Karlsson, S.8
  • 32
    • 79958812285 scopus 로고    scopus 로고
    • Hierarchy of immature hematopoietic cells related to blood flow and niche
    • Lévesque, J.P., and I.G. Winkler. 2011. Hierarchy of immature hematopoietic cells related to blood flow and niche. Curr. Opin. Hematol. 18:220- 225. http://dx.doi.org/19.1997/MOH.0b013e3283475fe7
    • (2011) Curr. Opin. Hematol. , vol.18
    • Lévesque, J.P.1    Winkler, I.G.2
  • 33
    • 0037237648 scopus 로고    scopus 로고
    • Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    • Lévesque, J.P., J. Hendy, Y. Takamatsu, P.J. Simmons, and L.J. Bendall. 2003. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J. Clin. Invest. 111:187-196.
    • (2003) J. Clin. Invest. , vol.111 , pp. 187-196
    • Lévesque, J.P.1    Hendy, J.2    Takamatsu, Y.3    Simmons, P.J.4    Bendall, L.J.5
  • 35
    • 84884210416 scopus 로고    scopus 로고
    • CFU-S
    • C.A. Klug, and C.T. Jordan, editors. Humana Press, Inc., Totowa, NJ.
    • McCulloch, E.A. 2002. CFU-S. In Hematopoietic Stem Cell Protocols. C.A. Klug, and C.T. Jordan, editors. Humana Press, Inc., Totowa, NJ. 153-160.
    • (2002) In Hematopoietic Stem Cell Protocols. , pp. 153-160
    • McCulloch, E.A.1
  • 37
    • 0031059252 scopus 로고    scopus 로고
    • Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization
    • Morrison, S.J., D.E. Wright, and I.L. Weissman. 1997. Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proc. Natl. Acad. Sci. USA. 94:1908- 1913. http://dx.doi.org/19.1973/pnas.94.5.1908
    • (1997) Proc. Natl. Acad. Sci. USA. , vol.94 , pp. 1908-1913
    • Morrison, S.J.1    Wright, D.E.2    Weissman, I.L.3
  • 39
    • 0031670654 scopus 로고
    • Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1
    • Munger, J.S., J.G. Harpel, F.G. Giancotti, and D.B. Rifkin. 1098. Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1. Mol. Biol. Cell. 9:2627-2638.
    • (1098) Mol. Biol. Cell. , vol.9 , pp. 2627-2638
    • Munger, J.S.1    Harpel, J.G.2    Giancotti, F.G.3    Rifkin, D.B.4
  • 40
    • 0033524949 scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis
    • Munger, J.S., X. Huang, H. Kawakatsu, M.J. Griffiths, S.L. Dalton, J. Wu, J.F. Pittet, N. Kaminski, C. Garat, M.A. Matthay, et al. 1099. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell. 96:319-328. http://dx.doi.org/10.1016/S0092-8674(00)80545-0
    • (1099) Cell. , vol.96 , pp. 319-328
    • Munger, J.S.1    Huang, X.2    Kawakatsu, H.3    Griffiths, M.J.4    Dalton, S.L.5    Wu, J.6    Pittet, J.F.7    Kaminski, N.8    Garat, C.9    Matthay, M.A.10
  • 42
    • 0030579203 scopus 로고
    • TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
    • Oshima, M., H. Oshima, and M.M. Taketo. 1096. TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev. Biol. 179:297-302. http://dx.doi.org/10.1006/dbio.1996.0259
    • (1096) Dev. Biol. , vol.179 , pp. 297-302
    • Oshima, M.1    Oshima, H.2    Taketo, M.M.3
  • 43
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • Passegué, E., A.J. Wagers, S. Giuriato, W.C. Anderson, and I.L. Weissman. 2005. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J. Exp. Med. 202:1599-1611. http://dx.doi.org/10.1084/jem.20050967
    • (2005) J. Exp. Med. , vol.202 , pp. 1599-1611
    • Passegué, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 45
    • 0031967817 scopus 로고
    • Concentration of transforming growth factor beta in human bone tissue: relationship to age, menopause, bone turnover, and bone volume
    • Pfeilschifter, J., I. Diel, B. Scheppach, A. Bretz, R. Krempien, J. Erdmann, G. Schmid, N. Reske, H. Bismar, T. Seck, et al. 1098. Concentration of transforming growth factor beta in human bone tissue: relationship to age, menopause, bone turnover, and bone volume. J. Bone Miner. Res. 13:716-730. http://dx.doi.org/10.1359/jbmr.1998.13.4.716
    • (1098) J. Bone Miner. Res. , vol.13 , pp. 716-730
    • Pfeilschifter, J.1    Diel, I.2    Scheppach, B.3    Bretz, A.4    Krempien, R.5    Erdmann, J.6    Schmid, G.7    Reske, N.8    Bismar, H.9    Seck, T.10
  • 47
    • 0033532054 scopus 로고
    • The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta
    • Ribeiro, S.M., M. Poczatek, S. Schultz-Cherry, M. Villain, and J.E. Murphy-Ullrich. 1099. The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta. J. Biol. Chem. 274:13586-13593. http://dx.doi.org/10.1074/jbc.274.19.13586
    • (1099) J. Biol. Chem. , vol.274 , pp. 13586-13593
    • Ribeiro, S.M.1    Poczatek, M.2    Schultz-Cherry, S.3    Villain, M.4    Murphy-Ullrich, J.E.5
  • 48
    • 0025310993 scopus 로고
    • Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system
    • Sato, Y., R. Tsuboi, R. Lyons, H. Moses, and D.B. Rifkin. 1990. Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system. J. Cell Biol. 111:757-763. http://dx.doi.org/10.1083/jcb.111.2.757
    • (1990) J. Cell Biol. , vol.111 , pp. 757-763
    • Sato, Y.1    Tsuboi, R.2    Lyons, R.3    Moses, H.4    Rifkin, D.B.5
  • 49
    • 6344293545 scopus 로고    scopus 로고
    • Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation
    • Scandura, J.M., P. Boccuni, J. Massagué, and S.D. Nimer. 2004. Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proc. Natl. Acad. Sci. USA. 101:15231-15236. http://dx.doi.org/10.1073/pnas.0406771101
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , pp. 15231-15236
    • Scandura, J.M.1    Boccuni, P.2    Massagué, J.3    Nimer, S.D.4
  • 50
    • 0035894949 scopus 로고    scopus 로고
    • Observation of antigen-dependent CD8+ T-cell/dendritic cell interactions in vivo
    • Schaefer, B.C., M.L. Schaefer, J.W. Kappler, P. Marrack, and R.M. Kedl. 2001. Observation of antigen-dependent CD8+ T-cell/dendritic cell interactions in vivo. Cell. Immunol. 214:110-122. http://dx.doi.org/10.1006/cimm.2001.1895
    • (2001) Cell. Immunol. , vol.214 , pp. 110-122
    • Schaefer, B.C.1    Schaefer, M.L.2    Kappler, J.W.3    Marrack, P.4    Kedl, R.M.5
  • 51
    • 0029948374 scopus 로고
    • Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells
    • Sitnicka, E., F.W. Ruscetti, G.V. Priestley, N.S. Wolf, and S.H. Bartelmez. 1096. Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells. Blood. 88:82-88.
    • (1096) Blood. , vol.88 , pp. 82-88
    • Sitnicka, E.1    Ruscetti, F.W.2    Priestley, G.V.3    Wolf, N.S.4    Bartelmez, S.H.5
  • 52
    • 0033962393 scopus 로고    scopus 로고
    • Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardation
    • Takahashi, K., K. Nakayama, and K. Nakayama. 2000. Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardation. J. Biochem. 127:73-83. http://dx.doi.org/10.1093/oxfordjournals.jbchem.a022586
    • (2000) J. Biochem. , vol.127 , pp. 73-83
    • Takahashi, K.1    Nakayama, K.2    Nakayama, K.3
  • 53
    • 67650506105 scopus 로고    scopus 로고
    • TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
    • Tang, Y., X. Wu, W. Lei, L. Pang, C. Wan, Z. Shi, L. Zhao, T.R. Nagy, X. Peng, J. Hu, et al. 2009. TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat. Med. 15:757-765. http://dx.doi.org/10.1038/nm.1979
    • (2009) Nat. Med. , vol.15 , pp. 757-765
    • Tang, Y.1    Wu, X.2    Lei, W.3    Pang, L.4    Wan, C.5    Shi, Z.6    Zhao, L.7    Nagy, T.R.8    Peng, X.9    Hu, J.10
  • 54
    • 80052276418 scopus 로고    scopus 로고
    • Breaking the cell cycle of HSCs by p57 and friends
    • Tesio, M., and A. Trumpp. 2011. Breaking the cell cycle of HSCs by p57 and friends. Cell Stem Cell. 9:187-192. http://dx.doi.org/10.1016/j.stem.2011.08.005
    • (2011) Cell Stem Cell. , vol.9 , pp. 187-192
    • Tesio, M.1    Trumpp, A.2
  • 55
    • 33644827383 scopus 로고    scopus 로고
    • Bone-marrow haematopoietic-stem-cell niches
    • Wilson, A., and A. Trumpp. 2006. Bone-marrow haematopoietic-stem-cell niches. Nat. Rev. Immunol. 6:93-106. http://dx.doi.org/10.1038/nri1779
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 93-106
    • Wilson, A.1    Trumpp, A.2
  • 57
    • 78049510298 scopus 로고    scopus 로고
    • Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling
    • Wu, X., L. Pang, W. Lei, W. Lu, J. Li, Z. Li, F.J. Frassica, X. Chen, M. Wan, and X. Cao. 2010. Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling. Cell Stem Cell. 7:571-580. http://dx.doi.org/10.1016/j.stem.2010.09.012
    • (2010) Cell Stem Cell. , vol.7 , pp. 571-580
    • Wu, X.1    Pang, L.2    Lei, W.3    Lu, W.4    Li, J.5    Li, Z.6    Frassica, F.J.7    Chen, X.8    Wan, M.9    Cao, X.10
  • 58
    • 33747613351 scopus 로고    scopus 로고
    • Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
    • Yamazaki, S., A. Iwama, S. Takayanagi, Y. Morita, K. Eto, H. Ema, and H. Nakauchi. 2006. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 25:3515-3523. http://dx.doi.org/10.1038/sj.emboj.7601236
    • (2006) EMBO J. , vol.25 , pp. 3515-3523
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.3    Morita, Y.4    Eto, K.5    Ema, H.6    Nakauchi, H.7
  • 59
    • 60849093771 scopus 로고    scopus 로고
    • TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation
    • Yamazaki, S., A. Iwama, S. Takayanagi, K. Eto, H. Ema, and H. Nakauchi. 2009. TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Blood. 113:1250-1256. http://dx.doi.org/10.1182/blood-2008-04-146480
    • (2009) Blood. , vol.113 , pp. 1250-1256
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.3    Eto, K.4    Ema, H.5    Nakauchi, H.6
  • 61
    • 0030955563 scopus 로고
    • Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development
    • Yan, Y., J. Frisén, M.H. Lee, J. Massagué, and M. Barbacid. 1097. Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev. 11:973-983.
    • (1097) Genes Dev. , vol.11 , pp. 973-983
    • Yan, Y.1    Frisén, J.2    Lee, M.H.3    Massagué, J.4    Barbacid, M.5
  • 63
    • 33947265169 scopus 로고    scopus 로고
    • Absence of integrin-mediated TGFbeta1 activation in vivo recapitulates the phenotype of TGFbeta1-null mice
    • Yang, Z., Z. Mu, B. Dabovic, V. Jurukovski, D. Yu, J. Sung, X. Xiong, and J.S. Munger. 2007. Absence of integrin-mediated TGFbeta1 activation in vivo recapitulates the phenotype of TGFbeta1-null mice. J. Cell Biol. 176:787-793. http://dx.doi.org/10.1083/jcb.200611044
    • (2007) J. Cell Biol. , vol.176 , pp. 787-793
    • Yang, Z.1    Mu, Z.2    Dabovic, B.3    Jurukovski, V.4    Yu, D.5    Sung, J.6    Xiong, X.7    Munger, J.S.8
  • 65
    • 31544481865 scopus 로고    scopus 로고
    • SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity
    • Yilmaz, O.H., M.J. Kiel, and S.J. Morrison. 2006. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood. 107:924-930. http://dx.doi.org/10.1182/blood-2005-05-2140
    • (2006) Blood. , vol.107 , pp. 924-930
    • Yilmaz, O.H.1    Kiel, M.J.2    Morrison, S.J.3
  • 66
    • 10444261212 scopus 로고    scopus 로고
    • Development of TGF-beta signalling inhibitors for cancer therapy
    • Yingling, J.M., K.L. Blanchard, and J.S. Sawyer. 2004. Development of TGF-beta signalling inhibitors for cancer therapy. Nat. Rev. Drug Discov. 3:1011-1022. http://dx.doi.org/10.1038/nrd1580
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 1011-1022
    • Yingling, J.M.1    Blanchard, K.L.2    Sawyer, J.S.3
  • 68
    • 0034650486 scopus 로고    scopus 로고
    • Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
    • Yu, Q., and I. Stamenkovic. 2000. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev. 14:163-176.
    • (2000) Genes Dev. , vol.14 , pp. 163-176
    • Yu, Q.1    Stamenkovic, I.2
  • 69
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Yuan, Y., H. Shen, D.S. Franklin, D.T. Scadden, and T. Cheng. 2004. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat. Cell Biol. 6:436-442. http://dx.doi.org/10.1038/ncb1126
    • (2004) Nat. Cell Biol. , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.