-
1
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El-Serag H.B., and Rudolph K.L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132 (2007) 2557-2576
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
1642544603
-
Focus on hepatocellular carcinoma
-
Bruix J., Boix J., Sala M., et al. Focus on hepatocellular carcinoma. Cancer Cell (2004) 215-219
-
(2004)
Cancer Cell
, pp. 215-219
-
-
Bruix, J.1
Boix, J.2
Sala, M.3
-
3
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi P.A., and DePinho R.A. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6 (2006) 674-687
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
4
-
-
0030057130
-
Clonal analysis of precancerous lesions of hepatocellular carcinoma
-
Aihara T., Noguchi S., Sasaki Y., et al. Clonal analysis of precancerous lesions of hepatocellular carcinoma. Gastroenterology 111 (1996) 455-461
-
(1996)
Gastroenterology
, vol.111
, pp. 455-461
-
-
Aihara, T.1
Noguchi, S.2
Sasaki, Y.3
-
5
-
-
0028804071
-
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
-
De Souza A.T., Hankins G.R., Washington M.K., et al. M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat Genet 11 (1995) 447-449
-
(1995)
Nat Genet
, vol.11
, pp. 447-449
-
-
De Souza, A.T.1
Hankins, G.R.2
Washington, M.K.3
-
6
-
-
0035093737
-
DNA double-strand breaks: signalling, repair and the cancer connection
-
Khanna K.K., and Jackson S.P. DNA double-strand breaks: signalling, repair and the cancer connection. Nat Genet 27 (2001) 247-254
-
(2001)
Nat Genet
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
7
-
-
0035289717
-
Chromosomal stability and the DNA double-stranded break connection
-
Van Gent D.C., Hoeijmakers J.H.J., and Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat Rev Genet 2 (2001) 196-206
-
(2001)
Nat Rev Genet
, vol.2
, pp. 196-206
-
-
Van Gent, D.C.1
Hoeijmakers, J.H.J.2
Kanaar, R.3
-
8
-
-
46249134069
-
Defective Ku70 DNA double strand break repair enhances hepatocarcinogenesis in mice
-
Teoh N., Dan Y.Y., Swisshelm K., et al. Defective Ku70 DNA double strand break repair enhances hepatocarcinogenesis in mice. Hepatology 47 (2008) 2078-2088
-
(2008)
Hepatology
, vol.47
, pp. 2078-2088
-
-
Teoh, N.1
Dan, Y.Y.2
Swisshelm, K.3
-
9
-
-
0028145285
-
Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration
-
Loyer P., Glaise D., Cariou S., et al. Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration. J Biol Chem 269 (1994) 2491-2500
-
(1994)
J Biol Chem
, vol.269
, pp. 2491-2500
-
-
Loyer, P.1
Glaise, D.2
Cariou, S.3
-
10
-
-
68949167576
-
Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage
-
Buitrago-Molina L.E., Pothiraju D., Lamle J., et al. Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage. Hepatology 50 (2009) 500
-
(2009)
Hepatology
, vol.50
, pp. 500
-
-
Buitrago-Molina, L.E.1
Pothiraju, D.2
Lamle, J.3
-
11
-
-
0036674617
-
Live or let die: the cell's response to p53
-
Vousden K.H., and Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2 (2002) 594-604
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
12
-
-
0037365789
-
ATM and related protein kinases: safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3 (2003) 155-168
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
13
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao H., and Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 21 (2001) 4129-4139
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
14
-
-
0035941021
-
ATR and ATRiP: partners in checkpoint signalling
-
Cortez D., Guntuku S., Qin J., et al. ATR and ATRiP: partners in checkpoint signalling. Science 294 (2001) 1713-1716
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
-
15
-
-
0033224201
-
A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins
-
Edwards R., Bentley N.J., and Carr A.M. A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins. Nat Cell Biol 1 (1999) 393-398
-
(1999)
Nat Cell Biol
, vol.1
, pp. 393-398
-
-
Edwards, R.1
Bentley, N.J.2
Carr, A.M.3
-
16
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double strand breaks
-
Cortez D., Wang Y., Qin J., et al. Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double strand breaks. Science 286 (1999) 1162-1166
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
-
17
-
-
7044274454
-
Genome scale profiling of gene expression in hepatocellular carcinoma: classification, survival prediction and identification of therapeutic targets
-
Lee J.S., and Thorgeirsson S.S. Genome scale profiling of gene expression in hepatocellular carcinoma: classification, survival prediction and identification of therapeutic targets. Gastroenterology 127 (2004) S51-S55
-
(2004)
Gastroenterology
, vol.127
-
-
Lee, J.S.1
Thorgeirsson, S.S.2
-
18
-
-
0030879563
-
atm and p53 Cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity
-
Westphal C.H., Rowan S., Schmaltz C., et al. atm and p53 Cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity. Nat Genet 16 (1997) 397-401
-
(1997)
Nat Genet
, vol.16
, pp. 397-401
-
-
Westphal, C.H.1
Rowan, S.2
Schmaltz, C.3
-
19
-
-
33846937033
-
Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W., Zender L., Miething C., et al. Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445 (2007) 656-660
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
-
20
-
-
33846899456
-
Restoration of p53 leads to tumor regression in vivo
-
Ventura A., Kirsch D.G., McLaughlin M.E., et al. Restoration of p53 leads to tumor regression in vivo. Nature 445 (2007) 661-665
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
-
21
-
-
0032923742
-
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
-
Jiang X.R., Jimenez G., Chang E., et al. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 21 (1999) 111-114
-
(1999)
Nat Genet
, vol.21
, pp. 111-114
-
-
Jiang, X.R.1
Jimenez, G.2
Chang, E.3
-
22
-
-
4043124073
-
Telomeres and telomerase: a dual role in hepatocarcinogenesis
-
Satyanarayana A., Manns M.P., and Rudolph K.L. Telomeres and telomerase: a dual role in hepatocarcinogenesis. Hepatology 40 (2004) 276-283
-
(2004)
Hepatology
, vol.40
, pp. 276-283
-
-
Satyanarayana, A.1
Manns, M.P.2
Rudolph, K.L.3
-
23
-
-
0037421896
-
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
-
Wong K.-K., Maser R., Bachoo R.M., et al. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 421 (2003) 643-647
-
(2003)
Nature
, vol.421
, pp. 643-647
-
-
Wong, K.-K.1
Maser, R.2
Bachoo, R.M.3
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