메뉴 건너뛰기




Volumn 20, Issue 11, 2014, Pages 1789-1809

The Multifunctional role and therapeutic potential of HO-1 in the vascular endothelium

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; BILIVERDIN; CARBON MONOXIDE; HEME OXYGENASE 1;

EID: 84896343373     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2013.5659     Document Type: Review
Times cited : (64)

References (200)
  • 1
    • 0344011671 scopus 로고    scopus 로고
    • Human heme oxygenase: Cell cycle-dependent expression and DNA mi-croarray identification of multiple gene responses after transduction of endothelial cells
    • Abraham NG, Scapagnini G, and Kappas A. Human heme oxygenase: cell cycle-dependent expression and DNA mi-croarray identification of multiple gene responses after transduction of endothelial cells. J Cell Biochem 90: 1098-1111, 2003.
    • (2003) J Cell Biochem , vol.90 , pp. 1098-1111
    • Abraham, N.G.1    Scapagnini, G.2    Kappas, A.3
  • 3
    • 15044365735 scopus 로고    scopus 로고
    • Protective effects of exogenous bilirubin on ischemia-reperfusion injury in the isolated, perfused rat kidney
    • Adin CA, Croker BP, and Agarwal A. Protective effects of exogenous bilirubin on ischemia-reperfusion injury in the isolated, perfused rat kidney. Am J Physiol Renal Physiol 288: F778-F784, 2005.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Adin, C.A.1    Croker, B.P.2    Agarwal, A.3
  • 4
    • 0028039868 scopus 로고
    • Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5¢ sequences are required for induction by heme or heavy metals
    • Alam J, Cai J, and Smith A. Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5¢ sequences are required for induction by heme or heavy metals. J Biol Chem 269: 1001-1009, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 1001-1009
    • Alam, J.1    Cai, J.2    Smith, A.3
  • 5
    • 0029019008 scopus 로고
    • Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer
    • Alam J, Camhi S, and Choi AM. Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer. J Biol Chem 270: 11977-11984, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 11977-11984
    • Alam, J.1    Camhi, S.2    Choi, A.M.3
  • 6
    • 33846924300 scopus 로고    scopus 로고
    • How many transcription factors does it take to turn on the heme oxygenase-1 gene?
    • Alam J and Cook JL. How many transcription factors does it take to turn on the heme oxygenase-1 gene? Am J Respir Cell Mol Biol 36: 166-174, 2007.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 166-174
    • Alam, J.1    Cook, J.L.2
  • 7
    • 76749083354 scopus 로고    scopus 로고
    • PPARd and PGC1a act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress
    • Ali F, Ali NS, Bauer A, Boyle JJ, Hamdulay SS, Haskard DO, Randi AM, and Mason JC. PPARd and PGC1a act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress. Cardiovasc Res 85: 701-710, 2010.
    • (2010) Cardiovasc Res , vol.85 , pp. 701-710
    • Ali, F.1    Ali, N.S.2    Bauer, A.3    Boyle, J.J.4    Hamdulay, S.S.5    Haskard, D.O.6    Randi, A.M.7    Mason, J.C.8
  • 11
    • 33646471962 scopus 로고    scopus 로고
    • Heme oxygenase attenuates oxidative stress and inflammation, and increases VEGF expression in portal hypertensive rats
    • Angermayr B, Mejias M, Gracia-Sancho J, Garcia-Pagan JC, Bosch J, and Fernandez M. Heme oxygenase attenuates oxidative stress and inflammation, and increases VEGF expression in portal hypertensive rats. J Hepatol 44: 1033-1039, 2006.
    • (2006) J Hepatol , vol.44 , pp. 1033-1039
    • Angermayr, B.1    Mejias, M.2    Gracia-Sancho, J.3    Garcia-Pagan, J.C.4    Bosch, J.5    Fernandez, M.6
  • 12
    • 84866176037 scopus 로고    scopus 로고
    • Heme oxygenase-1, oxidation, inflammation, and atherosclerosis
    • Araujo JA, Zhang M, and Yin F. Heme oxygenase-1, oxidation, inflammation, and atherosclerosis. Front Pharmacol 3: 119, 2012.
    • (2012) Front Pharmacol , vol.3 , Issue.119
    • Araujo, J.A.1    Zhang, M.2    Yin, F.3
  • 13
    • 77649284241 scopus 로고    scopus 로고
    • Shorter GT repeat polymorphism in the heme oxy-genase-1 gene promoter has protective effect on ische-mic stroke in dyslipidemia patients
    • Bai CH, Chen JR, Chiu HC, Chou CC, Chau LY, and Pan WH. Shorter GT repeat polymorphism in the heme oxy-genase-1 gene promoter has protective effect on ische-mic stroke in dyslipidemia patients. J Biomed Sci 17: 12, 2010.
    • J Biomed Sci , vol.17 , Issue.12 , pp. 2010
    • Bai, C.H.1    Chen, J.R.2    Chiu, H.C.3    Chou, C.C.4    Chau, L.Y.5    Pan, W.H.6
  • 14
    • 0025819677 scopus 로고
    • Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species
    • Balla G, Vercellotti GM, Muller-Eberhard U, Eaton J, and Jacob HS. Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species. Lab Invest 64: 648-655, 1991.
    • (1991) Lab Invest , vol.64 , pp. 648-655
    • Balla, G.1    Vercellotti, G.M.2    Muller-Eberhard, U.3    Eaton, J.4    Jacob, H.S.5
  • 16
    • 84861601576 scopus 로고    scopus 로고
    • Heme oxygenase-1 post-translational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment
    • Barone E, Di Domenico F, Sultana R, Coccia R, Mancuso C, Perluigi M, and Butterfield DA. Heme oxygenase-1 post-translational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. Free Radic Biol Med 52: 2292-2301, 2012.
    • (2012) Free Radic Biol Med , vol.52 , pp. 2292-2301
    • Barone, E.1    Di Domenico, F.2    Sultana, R.3    Coccia, R.4    Mancuso, C.5    Perluigi, M.6    Butterfield, D.A.7
  • 17
    • 65249103435 scopus 로고    scopus 로고
    • Nox4 NADPH oxidase mediates oxidative stress and apo-ptosis caused by TNF-alpha in cerebral vascular endothe-lial cells
    • Basuroy S, Bhattacharya S, Leffler CW, and Parfenova H. Nox4 NADPH oxidase mediates oxidative stress and apo-ptosis caused by TNF-alpha in cerebral vascular endothe-lial cells. Am J Physiol Cell Physiol 296: C422-C432, 2009.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Basuroy, S.1    Bhattacharya, S.2    Leffler, C.W.3    Parfenova, H.4
  • 22
    • 84855348346 scopus 로고    scopus 로고
    • Activating transcription factor 1 directs Mhem atheroprotective macrophages via coordinated iron handling and foam cell protection
    • Boyle JJ, Johns M, T. K, Nguyen AT, Game L, Schaer DJ, C. MJ, and Haskard DO. Activating transcription factor 1 directs Mhem atheroprotective macrophages via coordinated iron handling and foam cell protection. Circ Res 110: 20-33, 2012.
    • (2012) Circ Res , vol.110 , pp. 20-33
    • Boyle, J.J.1    Johns, M.2    Nguyen, A.T.3    Game, L.4    Schaer, D.J.5    Mj, C.6    Haskard, D.O.7
  • 25
    • 1642581763 scopus 로고    scopus 로고
    • Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: Induction of angio-genesis and inhibition of leukocytic infiltration
    • Bussolati B, Ahmed A, Pemberton H, C. LR, Di Carlo F, Haskard DO, and Mason JC. Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angio-genesis and inhibition of leukocytic infiltration. Blood 103: 761-766, 2004.
    • (2004) Blood , vol.103 , pp. 761-766
    • Bussolati, B.1    Ahmed, A.2    Pemberton, H.3    Lr, C.4    Di Carlo, F.5    Haskard, D.O.6    Mason, J.C.7
  • 26
    • 33746874131 scopus 로고    scopus 로고
    • Dual role of VEGF-induced heme-oxygenase-1 in angiogenesis
    • Bussolati B and Mason JC. Dual role of VEGF-induced heme-oxygenase-1 in angiogenesis. Antioxid Redox Signal 8: 1153-1163, 2006.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1153-1163
    • Bussolati, B.1    Mason, J.C.2
  • 28
    • 3142652478 scopus 로고    scopus 로고
    • Lumen digestion" technique for isolation of aortic endothelial cells from heme oxygenase-1 knockout mice
    • Chen S, Sega M, and Agarwal A. "Lumen digestion" technique for isolation of aortic endothelial cells from heme oxygenase-1 knockout mice. Biotechniques 37: 84-89, 2004.
    • (2004) Biotechniques , vol.37 , pp. 84-89
    • Chen, S.1    Sega, M.2
  • 32
    • 77957802876 scopus 로고    scopus 로고
    • Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein
    • Choi YK, Kim CK, Lee H, Jeoung D, Ha KS, Kwon YG, Kim KW, and Kim YM. Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein. J Biol Chem 285: 32116-32125, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 32116-32125
    • Choi, Y.K.1    Kim, C.K.2    Lee, H.3    Jeoung, D.4    Ha, K.S.5    Kwon, Y.G.6    Kim, K.W.7    Kim, Y.M.8
  • 36
    • 33745486718 scopus 로고    scopus 로고
    • Inhibition of cellular respiration by endogenously produced carbon monoxide
    • D'Amico G, Lam F, Hagen T, and Moncada S. Inhibition of cellular respiration by endogenously produced carbon monoxide. J Cell Sci 119: 2291-2298, 2006.
    • (2006) J Cell Sci , vol.119 , pp. 2291-2298
    • D'Amico, G.1    Lam, F.2    Hagen, T.3    Moncada, S.4
  • 37
    • 34848858001 scopus 로고    scopus 로고
    • Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2
    • Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, and Gimbrone MA, Jr. Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2. Circ Res 101: 723-733, 2007.
    • (2007) Circ Res , vol.101 , pp. 723-733
    • Dai, G.1    Vaughn, S.2    Zhang, Y.3    Wang, E.T.4    Garcia-Cardena, G.5    Gimbrone Jr., M.A.6
  • 38
    • 34548855958 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress
    • Datla SR, Dusting GJ, Mori TA, Taylor CJ, Croft KD, and Jiang F. Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress. Hypertension 50: 636-642, 2007.
    • (2007) Hypertension , vol.50 , pp. 636-642
    • Datla, S.R.1    Dusting, G.J.2    Mori, T.A.3    Taylor, C.J.4    Croft, K.D.5    Jiang, F.6
  • 40
    • 14444268977 scopus 로고    scopus 로고
    • Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis
    • Deramaudt BM, Braunstein S, Remy P, and Abraham NG. Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis. J Cell Biochem 68: 121-127, 1998.
    • (1998) J Cell Biochem , vol.68 , pp. 121-127
    • Deramaudt, B.M.1    Braunstein, S.2    Remy, P.3    Abraham, N.G.4
  • 42
    • 12344261026 scopus 로고    scopus 로고
    • Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis
    • Devesa I, Ferrandiz ML, Guillen I, Cerda JM, and Alcaraz MJ. Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis. Lab Invest 85: 34-44, 2005.
    • (2005) Lab Invest , vol.85 , pp. 34-44
    • Devesa, I.1    Ferrandiz, M.L.2    Guillen, I.3    Cerda, J.M.4    Alcaraz, M.J.5
  • 43
  • 49
    • 4644226200 scopus 로고    scopus 로고
    • The role of heme oxygenase-1 promoter polymorphisms in human disease
    • Exner M, Minar E, Wagner O, and Schillinger M. The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic Biol Med 37: 1097-1104, 2004.
    • (2004) Free Radic Biol Med , vol.37 , pp. 1097-1104
    • Exner, M.1    Minar, E.2    Wagner, O.3    Schillinger, M.4
  • 51
    • 0038001984 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane
    • Fernandez M and Bonkovsky HL. Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane. Br J Pharmacol 139: 634-640, 2003.
    • (2003) Br J Pharmacol , vol.139 , pp. 634-640
    • Fernandez, M.1    Bonkovsky, H.L.2
  • 53
    • 84857029789 scopus 로고    scopus 로고
    • Acute myocardial infarction in strepto-zotocin-induced hyperglycaemic rats: Protection by a carbon monoxide-releasing molecule (CORM-3)
    • Filippo CD, Perretti M, Rossi F, Ferraraccio F, Motterlini R, and D'Amico M. Acute myocardial infarction in strepto-zotocin-induced hyperglycaemic rats: protection by a carbon monoxide-releasing molecule (CORM-3). Naunyn Schmiedebergs Arch Pharmacol 385: 137-144, 2012.
    • (2012) Naunyn Schmiedebergs Arch Pharmacol , vol.385 , pp. 137-144
    • Filippo, C.D.1    Perretti, M.2    Rossi, F.3    Ferraraccio, F.4    Motterlini, R.5    D'Amico, M.6
  • 54
    • 77958086954 scopus 로고    scopus 로고
    • Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase
    • Fujii M, Inoguchi T, Sasaki S, Maeda Y, Zheng J, Kobayashi K, and Takayanagi R. Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase. Kidney Int 78: 905-919, 2010.
    • (2010) Kidney Int , vol.78 , pp. 905-919
    • Fujii, M.1    Inoguchi, T.2    Sasaki, S.3    Maeda, Y.4    Zheng, J.5    Kobayashi, K.6    Takayanagi, R.7
  • 55
    • 0038714320 scopus 로고    scopus 로고
    • Characterization of a new double-filament model of focal cerebral ischemia in heme oxygenase-2-deficient mice
    • Goto S, Sampei K, Alkayed NJ, Dore S, and Koehler RC. Characterization of a new double-filament model of focal cerebral ischemia in heme oxygenase-2-deficient mice. Am J Physiol Regul Integr Comp Physiol 285: R222-R230, 2003.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.285
    • Goto, S.1    Sampei, K.2    Alkayed, N.J.3    Dore, S.4    Koehler, R.C.5
  • 57
    • 33846639179 scopus 로고    scopus 로고
    • Statins and the vascular endo-thelial inflammatory response
    • Greenwood J and Mason JC. Statins and the vascular endo-thelial inflammatory response. Trends Immunol 28: 88-98, 2007.
    • (2007) Trends Immunol , vol.28 , pp. 88-98
    • Greenwood, J.1    Mason, J.C.2
  • 60
    • 77950521629 scopus 로고    scopus 로고
    • Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium
    • Hamdulay SS, Wang B, Birdsey GM, Ali F, Dumont O, Evans PC, Haskard DO, Wheeler-Jones CP, and Mason JC. Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. Free Radic Biol Med 48: 1013-1023, 2010.
    • (2010) Free Radic Biol Med , vol.48 , pp. 1013-1023
    • Hamdulay, S.S.1    Wang, B.2    Birdsey, G.M.3    Ali, F.4    Dumont, O.5    Evans, P.C.6    Haskard, D.O.7    Wheeler-Jones, C.P.8    Mason, J.C.9
  • 61
    • 0036096578 scopus 로고    scopus 로고
    • Cross talk between carbon monoxide and nitric oxide
    • Hartsfield CL. Cross talk between carbon monoxide and nitric oxide. Antioxid Redox Signal 4: 301-307, 2002.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 301-307
    • Hartsfield, C.L.1
  • 62
    • 0033370832 scopus 로고    scopus 로고
    • Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells
    • Hartsfield CL, Alam J, and Choi AM. Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells. Am J Physiol 277: L1133-L1141, 1999.
    • (1999) Am J Physiol , vol.277
    • Hartsfield, C.L.1    Alam, J.2    Choi, A.M.3
  • 63
    • 3042799349 scopus 로고    scopus 로고
    • Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene
    • Hayashi S, Omata Y, Sakamoto H, Higashimoto Y, Hara T, Sagara Y, and Noguchi M. Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene. Gene 336: 241-250, 2004.
    • (2004) Gene , vol.336 , pp. 241-250
    • Hayashi, S.1    Omata, Y.2    Sakamoto, H.3    Higashimoto, Y.4    Hara, T.5    Sagara, Y.6    Noguchi, M.7
  • 66
    • 77954761548 scopus 로고    scopus 로고
    • Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human en-dothelial cells
    • Hinkelmann U, Grosser N, Erdmann K, Schroder H, and Immenschuh S. Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human en-dothelial cells. Eur J Pharm Sci 41: 118-124, 2010.
    • (2010) Eur J Pharm Sci , vol.41 , pp. 118-124
    • Hinkelmann, U.1    Grosser, N.2    Erdmann, K.3    Schroder, H.4    Immenschuh, S.5
  • 67
    • 33845696649 scopus 로고    scopus 로고
    • Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice
    • Hirai K, Sasahira T, Ohmori H, Fujii K, and Kuniyasu H. Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice. Int J Cancer 120: 500-505, 2007.
    • (2007) Int J Cancer , vol.120 , pp. 500-505
    • Hirai, K.1    Sasahira, T.2    Ohmori, H.3    Fujii, K.4    Kuniyasu, H.5
  • 68
    • 0033605676 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling
    • Huang LE, Willmore WG, Gu J, Goldberg MA, and Bunn HF. Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling. J Biol Chem 274: 9038-9044, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 9038-9044
    • Huang, L.E.1    Willmore, W.G.2    Gu, J.3    Goldberg, M.A.4    Bunn, H.F.5
  • 69
    • 78049269927 scopus 로고    scopus 로고
    • Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells
    • Ishikado A, Nishio Y, Morino K, Ugi S, Kondo H, Makino T, Kashiwagi A, and Maegawa H. Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells. Biochem Biophys Res Commun 402: 99-104, 2010.
    • (2010) Biochem Biophys Res Commun , vol.402 , pp. 99-104
    • Ishikado, A.1    Nishio, Y.2    Morino, K.3    Ugi, S.4    Kondo, H.5    Makino, T.6    Kashiwagi, A.7    Maegawa, H.8
  • 70
    • 84866165298 scopus 로고    scopus 로고
    • Vasculitis, atherosclerosis, and altered HDL composition in heme-oxygenase-1-knockout mice
    • Ishikawa K, Navab M, and Lusis AJ. Vasculitis, atherosclerosis, and altered HDL composition in heme-oxygenase-1-knockout mice. Int J Hypertens 2012: 948203, 2012.
    • (2012) Int J Hypertens
    • Ishikawa, K.1    Navab, M.2    Lusis, A.J.3
  • 72
    • 77953704443 scopus 로고    scopus 로고
    • Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin
    • Jansen T, Hortmann M, Oelze M, Opitz B, Steven S, Schell R, Knorr M, Karbach S, Schuhmacher S, Wenzel P, Munzel T, and Daiber A. Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin. J Mol Cell Cardiol 49: 186-195, 2010.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 186-195
    • Jansen, T.1    Hortmann, M.2    Oelze, M.3    Opitz, B.4    Steven, S.5    Schell, R.6    Knorr, M.7    Karbach, S.8    Schuhmacher, S.9    Wenzel, P.10    Munzel, T.11    Daiber, A.12
  • 75
    • 0037217407 scopus 로고    scopus 로고
    • Heme oxygenase inhibitor restores arteriolar nitric oxide function in dahl rats
    • Johnson FK, Durante W, Peyton KJ, and Johnson RA. Heme oxygenase inhibitor restores arteriolar nitric oxide function in dahl rats. Hypertension 41: 149-155, 2003.
    • (2003) Hypertension , vol.41 , pp. 149-155
    • Johnson, F.K.1    Durante, W.2    Peyton, K.J.3    Johnson, R.A.4
  • 76
    • 0043132417 scopus 로고    scopus 로고
    • Carbon monoxide promotes endothelium-dependent constriction of isolated gracilis muscle arterioles
    • Johnson FK and Johnson RA. Carbon monoxide promotes endothelium-dependent constriction of isolated gracilis muscle arterioles. Am J Physiol Regul Integr Comp Physiol 285: R536-R541, 2003.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.285
    • Johnson, F.K.1    Johnson, R.A.2
  • 77
    • 77957234852 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency leads to alteration of soluble guanylate cyclase redox regulation
    • Jones AW, Durante W, and Korthuis RJ. Heme oxygenase-1 deficiency leads to alteration of soluble guanylate cyclase redox regulation. J Pharmacol Exp Ther 335: 85-91, 2010.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 85-91
    • Jones, A.W.1    Durante, W.2    Korthuis, R.J.3
  • 79
    • 1642531778 scopus 로고    scopus 로고
    • Heme oxygenase and angiogenic activity of endothelial cells: Stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX
    • Józkowicz A, Huk I, Nigisch A, Weigel G, Dietrich W, Motterlini R, and Dulak J. Heme oxygenase and angiogenic activity of endothelial cells: stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX. Antioxid Redox Signal 5: 155-162, 2003.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 155-162
    • Józkowicz, A.1    Huk, I.2    Nigisch, A.3    Weigel, G.4    Dietrich, W.5    Motterlini, R.6    Dulak, J.7
  • 81
    • 35848942608 scopus 로고    scopus 로고
    • Heme oxygenase-1 in tumors: Is it a false friend?
    • Jozkowicz A, Was H, and Dulak J. Heme oxygenase-1 in tumors: is it a false friend? Antioxid Redox Signal 9: 2099-2117, 2007.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 2099-2117
    • Jozkowicz, A.1    Was, H.2    Dulak, J.3
  • 82
    • 0035949615 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice
    • Juan SH, Lee TS, Tseng KW, Liou JY, Shyue SK, Wu KK, and Chau LY. Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation 104: 1519-1525, 2001.
    • (2001) Circulation , vol.104 , pp. 1519-1525
    • Juan, S.H.1    Lee, T.S.2    Tseng, K.W.3    Liou, J.Y.4    Shyue, S.K.5    Wu, K.K.6    Chau, L.Y.7
  • 84
    • 0042031556 scopus 로고    scopus 로고
    • Bilirubin rinse: A simple protectant against the rat liver graft injury mimicking heme oxygenase-1 preconditioning
    • Kato Y, Shimazu M, Kondo M, Uchida K, Kumamoto Y, Wakabayashi G, Kitajima M, and Suematsu M. Bilirubin rinse: a simple protectant against the rat liver graft injury mimicking heme oxygenase-1 preconditioning. Hepatology 38: 364-373, 2003.
    • (2003) Hepatology , vol.38 , pp. 364-373
    • Kato, Y.1    Shimazu, M.2    Kondo, M.3    Uchida, K.4    Kumamoto, Y.5    Wakabayashi, G.6    Kitajima, M.7    Suematsu, M.8
  • 89
    • 61849124659 scopus 로고    scopus 로고
    • Heme-oxygenase-1 expression enhances vascular en-dothelial resistance to complement-mediated injury through induction of decay-accelerating factor. A role for bilirubin and ferritin
    • Kinderlerer AR, Gregoire IP, Hamdulay SS, Steinberg R, Ali F, Silva G, Ali N, Haskard DO, Soares MP, and Mason JC. Heme-oxygenase-1 expression enhances vascular en-dothelial resistance to complement-mediated injury through induction of decay-accelerating factor. A role for bilirubin and ferritin. Blood 113: 1598-1607, 2009.
    • (2009) Blood , vol.113 , pp. 1598-1607
    • Kinderlerer, A.R.1    Gregoire, I.P.2    Hamdulay, S.S.3    Steinberg, R.4    Ali, F.5    Silva, G.6    Ali, N.7    Haskard, D.O.8    Soares, M.P.9    Mason, J.C.10
  • 93
    • 78650676293 scopus 로고    scopus 로고
    • Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: Effects on macrophage viability and tissue iron distribution
    • Kovtunovych G, Eckhaus MA, Ghosh MC, Ollivierre-Wilson H, and Rouault TA. Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. Blood 116: 6054-6062, 2010.
    • (2010) Blood , vol.116 , pp. 6054-6062
    • Kovtunovych, G.1    Eckhaus, M.A.2    Ghosh, M.C.3    Ollivierre-Wilson, H.4    Rouault, T.A.5
  • 96
    • 77952306257 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide promote neo-vascularization after myocardial infarction by modulating the expression of HIF-1alpha, SDF-1alpha and VEGF-B
    • Lakkisto P, Kyto V, Forsten H, Siren JM, Segersvard H, Voipio-Pulkki LM, Laine M, Pulkki K, and Tikkanen I. Heme oxygenase-1 and carbon monoxide promote neo-vascularization after myocardial infarction by modulating the expression of HIF-1alpha, SDF-1alpha and VEGF-B. Eur J Pharmacol 635: 156-164, 2010.
    • (2010) Eur J Pharmacol , vol.635 , pp. 156-164
    • Lakkisto, P.1    Kyto, V.2    Forsten, H.3    Siren, J.M.4    Segersvard, H.5    Voipio-Pulkki, L.M.6    Laine, M.7    Pulkki, K.8    Tikkanen, I.9
  • 97
    • 84896376590 scopus 로고    scopus 로고
    • Heme oxygenase-2 (HO-2) knockout mice display impaired corneal wound healing and marked corneal neovascularization
    • E-abstract 3619
    • Laniado-Schwartzman M. MA, Seta F, Dunn MW, Abraham NG, and Gronert K. Heme oxygenase-2 (HO-2) knockout mice display impaired corneal wound healing and marked corneal neovascularization. Invest Ophthalmol Vis Sci 46: E-abstract 3619, 2005.
    • (2005) Invest Ophthalmol Vis Sci , vol.46
    • Laniado-Schwartzman, M.M.A.1    Seta, F.2    Dunn, M.W.3    Abraham, N.G.4    Gronert, K.5
  • 98
    • 0031041377 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates tran-scriptional activation of the heme oxygenase-1 gene in response to hypoxia
    • Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, and Choi AM. Hypoxia-inducible factor-1 mediates tran-scriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 5375-5381
    • Lee, P.J.1    Jiang, B.H.2    Chin, B.Y.3    Iyer, N.V.4    Alam, J.5    Semenza, G.L.6    Choi, A.M.7
  • 99
    • 79951767414 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells
    • Lee SE, Jeong SI, Kim GD, Yang H, Park CS, Jin YH, and Park YS. Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells. Toxicol Lett 201: 240-248, 2011.
    • (2011) Toxicol Lett , vol.201 , pp. 240-248
    • Lee, S.E.1    Jeong, S.I.2    Kim, G.D.3    Yang, H.4    Park, C.S.5    Jin, Y.H.6    Park, Y.S.7
  • 100
    • 4444369432 scopus 로고    scopus 로고
    • Simvastatin induces heme oxygenase-1: A novel mechanism of vessel protection
    • Lee TS, Chang CC, Zhu Y, and Shyy JY. Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation 110: 1296-1302, 2004.
    • (2004) Circulation , vol.110 , pp. 1296-1302
    • Lee, T.S.1    Chang, C.C.2    Zhu, Y.3    Shyy, J.Y.4
  • 101
    • 81255157580 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis
    • Li T, Tian H, Zhao Y, An F, Zhang L, Zhang J, Peng J, Zhang Y, and Guo Y. Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis. Eur J Pharmacol 672: 143-152, 2011.
    • (2011) Eur J Pharmacol , vol.672 , pp. 143-152
    • Li, T.1    Tian, H.2    Zhao, Y.3    An, F.4    Zhang, L.5    Zhang, J.6    Peng, J.7    Zhang, Y.8    Guo, Y.9
  • 103
    • 0036392112 scopus 로고    scopus 로고
    • Differential effect of heme-oxygenase-1 in endothelial and smooth muscle cell cycle progression
    • Li Volti G, Wang J, Traganos F, Kappas A, and Abraham NG. Differential effect of heme-oxygenase-1 in endothelial and smooth muscle cell cycle progression. Biochem Biophys Res Commun 296: 1077-1082, 2002.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 1077-1082
    • Li Volti, G.1    Wang, J.2    Traganos, F.3    Kappas, A.4    Abraham, N.G.5
  • 104
    • 67949099048 scopus 로고    scopus 로고
    • After vascular injury, heme oxygenase-1/carbon monoxide enhances re-endothelialization via promoting mobilization of circulating endothelial progenitor cells
    • Lin HH, Chen YH, Yet SF, and Chau LY. After vascular injury, heme oxygenase-1/carbon monoxide enhances re-endothelialization via promoting mobilization of circulating endothelial progenitor cells. J Thromb Haemost 7: 1401-1408, 2009.
    • (2009) J Thromb Haemost , vol.7 , pp. 1401-1408
    • Lin, H.H.1    Chen, Y.H.2    Yet, S.F.3    Chau, L.Y.4
  • 105
    • 79952811645 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide induces vascular endothelial growth factor expression via p38 kinase-dependent activation of Sp1
    • Lin HH, Lai SC, and Chau LY. Heme oxygenase-1/carbon monoxide induces vascular endothelial growth factor expression via p38 kinase-dependent activation of Sp1. J Biol Chem 286: 3829-3838, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 3829-3838
    • Lin, H.H.1    Lai, S.C.2    Chau, L.Y.3
  • 106
    • 50849145160 scopus 로고    scopus 로고
    • Ubiquitin-proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway
    • Lin PH, Chiang MT, and Chau LY. Ubiquitin-proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway. Biochim Biophys Acta 1783: 1826-1834, 2008.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 1826-1834
    • Lin, P.H.1    Chiang, M.T.2    Chau, L.Y.3
  • 107
    • 14644400430 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates myocardial ischemia/re-perfusion injury in diabetic mice
    • Liu X, Wei J, Peng DH, Layne MD, and Yet SF. Absence of heme oxygenase-1 exacerbates myocardial ischemia/re-perfusion injury in diabetic mice. Diabetes 54: 778-784, 2005.
    • (2005) Diabetes , vol.54 , pp. 778-784
    • Liu, X.1    Wei, J.2    Peng, D.H.3    Layne, M.D.4    Yet, S.F.5
  • 109
    • 84866128524 scopus 로고    scopus 로고
    • Sildenafil stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells via distinct signaling pathways
    • Liu XM, Peyton KJ, Wang X, and Durante W. Sildenafil stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells via distinct signaling pathways. Biochem Pharmacol 84: 1045-1054, 2012.
    • (2012) Biochem Pharmacol , vol.84 , pp. 1045-1054
    • Liu, X.M.1    Peyton, K.J.2    Wang, X.3    Durante, W.4
  • 110
    • 0037532741 scopus 로고    scopus 로고
    • Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: Implications for the role of oxidative stress in the development of multiple sclerosis
    • Liu Y, Zhu B, Wang X, Luo L, Li P, Paty DW, and Cynader MS. Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: implications for the role of oxidative stress in the development of multiple sclerosis. J Neuroimmunol 139: 27-35, 2003.
    • (2003) J Neuroimmunol , vol.139 , pp. 27-35
    • Liu, Y.1    Zhu, B.2    Wang, X.3    Luo, L.4    Li, P.5    Paty, D.W.6    Cynader, M.S.7
  • 112
    • 70350351419 scopus 로고    scopus 로고
    • Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase
    • Maghzal GJ, Leck MC, Collinson E, Li C, and Stocker R. Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase. J Biol Chem 284: 29251-29259, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 29251-29259
    • Maghzal, G.J.1    Leck, M.C.2    Collinson, E.3    Li, C.4    Stocker, R.5
  • 113
    • 0022632224 scopus 로고
    • Characterization of two constitutive forms of rat liver microsomal heme oxygenase. only one molecular species of the enzyme is inducible
    • Maines MD, Trakshel GM, and Kutty RK. Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem 261: 411-419, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 411-419
    • Maines, M.D.1    Trakshel, G.M.2    Kutty, R.K.3
  • 114
    • 84865212337 scopus 로고    scopus 로고
    • Carbon monoxide (CO)-releasing molecule-derived CO regulates tissue factor and plasmin-ogen activator inhibitor type 1 in human endothelial cells
    • Maruyama K, Morishita E, Yuno T, Sekiya A, Asakura H, Ohtake S, and Yachie A. Carbon monoxide (CO)-releasing molecule-derived CO regulates tissue factor and plasmin-ogen activator inhibitor type 1 in human endothelial cells. Thromb Res 130: e188-e193, 2012.
    • (2012) Thromb Res , vol.130
    • Maruyama, K.1    Morishita, E.2    Yuno, T.3    Sekiya, A.4    Asakura, H.5    Ohtake, S.6    Yachie, A.7
  • 116
    • 0028838293 scopus 로고
    • Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide
    • Morita T and Kourembanas S. Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide. J Clin Invest 96: 2676-2682, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 2676-2682
    • Morita, T.1    Kourembanas, S.2
  • 117
    • 0034607632 scopus 로고    scopus 로고
    • Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols
    • Motterlini R, Foresti R, Bassi R, Calabrese V, Clark JE, and Green CJ. Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols. J Biol Chem 275: 13613-13620, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 13613-13620
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Calabrese, V.4    Clark, J.E.5    Green, C.J.6
  • 118
    • 84887617601 scopus 로고    scopus 로고
    • Emerging concepts on the anti-inflammatory actions of carbon monoxide-releasing molecules (CO-RMs)
    • Motterlini R, Haas B, and Foresti R. Emerging concepts on the anti-inflammatory actions of carbon monoxide-releasing molecules (CO-RMs). Med Gas Res 2: 28, 2012.
    • (2012) Med Gas Res , vol.2 , Issue.28
    • Motterlini, R.1    Haas, B.2    Foresti, R.3
  • 119
    • 77956323967 scopus 로고    scopus 로고
    • The therapeutic potential of carbon monoxide
    • Motterlini R and Otterbein LE. The therapeutic potential of carbon monoxide. Nat Rev Drug Discov 9: 728-743, 2010.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 728-743
    • Motterlini, R.1    Otterbein, L.E.2
  • 121
    • 36348957437 scopus 로고    scopus 로고
    • Statin treatment increases formation of carbon monoxide and bilirubin in mice: A novel mechanism of in vivo antioxidant protection
    • Muchova L, Wong RJ, Hsu M, Morioka I, Vitek L, Zelenka J, Schroder H, and Stevenson DK. Statin treatment increases formation of carbon monoxide and bilirubin in mice: a novel mechanism of in vivo antioxidant protection. Can J Physiol Pharmacol 85: 800-810, 2007.
    • (2007) Can J Physiol Pharmacol , vol.85 , pp. 800-810
    • Muchova, L.1    Wong, R.J.2    Hsu, M.3    Morioka, I.4    Vitek, L.5    Zelenka, J.6    Schroder, H.7    Stevenson, D.K.8
  • 122
    • 0027452195 scopus 로고
    • A beneficial role of bile pigments as an endogenous tissue protector: Anti-complement effects of biliverdin and conjugated bilirubin
    • Nakagami T, Toyomura K, Kinoshita T, and Morisawa S. A beneficial role of bile pigments as an endogenous tissue protector: anti-complement effects of biliverdin and conjugated bilirubin. Biochim Biophys Acta 1158: 189-193, 1993.
    • (1993) Biochim Biophys Acta , vol.1158 , pp. 189-193
    • Nakagami, T.1    Toyomura, K.2    Kinoshita, T.3    Morisawa, S.4
  • 124
    • 23044447945 scopus 로고    scopus 로고
    • Biliverdin administration prevents the formation of intimal hyperplasia induced by vascular injury
    • Nakao A, Murase N, Ho C, Toyokawa H, Billiar TR, and Kanno S. Biliverdin administration prevents the formation of intimal hyperplasia induced by vascular injury. Circulation 112: 587-591, 2005.
    • (2005) Circulation , vol.112 , pp. 587-591
    • Nakao, A.1    Murase, N.2    Ho, C.3    Toyokawa, H.4    Billiar, T.R.5    Kanno, S.6
  • 128
    • 70549084059 scopus 로고    scopus 로고
    • Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells
    • Nizamutdinova IT, Kim YM, Kim HJ, Seo HG, Lee JH, and Chang KC. Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells. Atherosclerosis 207: 405-411, 2009.
    • (2009) Atherosclerosis , vol.207 , pp. 405-411
    • Nizamutdinova, I.T.1    Kim, Y.M.2    Kim, H.J.3    Seo, H.G.4    Lee, J.H.5    Chang, K.C.6
  • 135
    • 17744385995 scopus 로고    scopus 로고
    • A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells
    • Pae HO, Oh GS, Choi BM, Kim YM, and Chung HT. A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells. Endocrinology 146: 2229-2238, 2005.
    • (2005) Endocrinology , vol.146 , pp. 2229-2238
    • Pae, H.O.1    Oh, G.S.2    Choi, B.M.3    Kim, Y.M.4    Chung, H.T.5
  • 136
    • 78049442406 scopus 로고    scopus 로고
    • Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
    • Paine A, Eiz-Vesper B, Blasczyk R, and Immenschuh S. Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem Pharmacol 80: 1895-1903, 2010.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1895-1903
    • Paine, A.1    Eiz-Vesper, B.2    Blasczyk, R.3    Immenschuh, S.4
  • 137
    • 33646436473 scopus 로고    scopus 로고
    • Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: Contributions of HO-1 and HO-2 to cytoprotection
    • Parfenova H, Basuroy S, Bhattacharya S, Tcheranova D, Qu Y, Regan RF, and Leffler CW. Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection. Am J Physiol Cell Physiol 290: C1399-C1410, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Parfenova, H.1    Basuroy, S.2    Bhattacharya, S.3    Tcheranova, D.4    Qu, Y.5    Regan, R.F.6    Leffler, C.W.7
  • 138
    • 67549134935 scopus 로고    scopus 로고
    • Targeting heme oxygenase: Therapeutic implications for diseases of the cardiovascular system
    • Peterson SJ, Frishman WH, and Abraham NG. Targeting heme oxygenase: therapeutic implications for diseases of the cardiovascular system. Cardiol Rev 17: 99-111, 2009.
    • (2009) Cardiol Rev , vol.17 , pp. 99-111
    • Peterson, S.J.1    Frishman, W.H.2    Abraham, N.G.3
  • 139
    • 0036090811 scopus 로고    scopus 로고
    • Biological chemistry of carbon monoxide
    • Piantadosi CA. Biological chemistry of carbon monoxide. Antioxid Redox Signal 4: 259-270, 2002.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 259-270
    • Piantadosi, C.A.1
  • 140
    • 77957897673 scopus 로고    scopus 로고
    • Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]-derivatives
    • Pitchumony TS, Spingler B, Motterlini R, and Alberto R. Syntheses, structural characterization and CO releasing properties of boranocarbonate
    • (2010) Org Biomol Chem , vol.8 , pp. 4849-4854
    • Pitchumony, T.S.1    Spingler, B.2    Motterlini, R.3    Alberto, R.4
  • 141
    • 0030886054 scopus 로고    scopus 로고
    • Reduced stress defense in heme oxygenase 1-deficient cells
    • Poss KD and Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 94: 10925-10930, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10925-10930
    • Poss, K.D.1    Tonegawa, S.2
  • 142
    • 28844446987 scopus 로고    scopus 로고
    • Molecular basis of heme oxygenase-1 induction: Implications for chemoprevention and chemoprotection
    • Prawan A, Kundu JK, and Surh YJ. Molecular basis of heme oxygenase-1 induction: implications for chemoprevention and chemoprotection. Antioxid Redox Signal 7: 1688-1703, 2005.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1688-1703
    • Prawan, A.1    Kundu, J.K.2    Surh, Y.J.3
  • 143
    • 84865106571 scopus 로고    scopus 로고
    • Epigalloca-techin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-alpha
    • Pullikotil P, Chen H, Muniyappa R, Greenberg CC, Yang S, Reiter CE, Lee JW, Chung JH, and Quon MJ. Epigalloca-techin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-alpha. J Nutr Biochem 23: 1134-1145, 2012.
    • (2012) J Nutr Biochem , vol.23 , pp. 1134-1145
    • Pullikotil, P.1    Chen, H.2    Muniyappa, R.3    Greenberg, C.C.4    Yang, S.5    Reiter, C.E.6    Lee, J.W.7    Chung, J.H.8    Quon, M.J.9
  • 145
    • 84872804281 scopus 로고    scopus 로고
    • Carbon monoxide: Mechanisms of action and potential clinical implications
    • Rochette L, Cottin Y, Zeller M, and Vergely C. Carbon monoxide: mechanisms of action and potential clinical implications. Pharmacol Ther 137: 133-152, 2013.
    • (2013) Pharmacol Ther , vol.137 , pp. 133-152
    • Rochette, L.1    Cottin, Y.2    Zeller, M.3    Vergely, C.4
  • 148
    • 0036670493 scopus 로고    scopus 로고
    • Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells
    • Ryter SW, Xi S, Hartsfield CL, and Choi AM. Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells. Antioxid Redox Signal 4: 587-592, 2002.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 587-592
    • Ryter, S.W.1    Xi, S.2    Hartsfield, C.L.3    Choi, A.M.4
  • 151
    • 38849203158 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276
    • Seldon MP, Silva G, Pejanovic N, Larsen R, Gregoire IP, Filipe J, Anrather J, and Soares MP. Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276. J Immunol 179: 7840-7851, 2007.
    • (2007) J Immunol , vol.179 , pp. 7840-7851
    • Seldon, M.P.1    Silva, G.2    Pejanovic, N.3    Larsen, R.4    Gregoire, I.P.5    Filipe, J.6    Anrather, J.7    Soares, M.P.8
  • 153
    • 56749170891 scopus 로고    scopus 로고
    • Heme induces endothelial tissue factor expression: Potential role in he-mostatic activation in patients with hemolytic anemia
    • Setty BN, Betal SG, Zhang J, and Stuart MJ. Heme induces endothelial tissue factor expression: potential role in he-mostatic activation in patients with hemolytic anemia. J Thromb Haemost 6: 2202-2209, 2008.
    • (2008) J Thromb Haemost , vol.6 , pp. 2202-2209
    • Setty, B.N.1    Betal, S.G.2    Zhang, J.3    Stuart, M.J.4
  • 155
    • 78649480344 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells
    • Shih RH and Yang CM. Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells. J Neuroin-flammation 7: 86, 2010.
    • J Neuroin-flammation , vol.7 , Issue.86 , pp. 2010
    • Shih, R.H.1    Yang, C.M.2
  • 156
    • 33746215182 scopus 로고    scopus 로고
    • The antiapoptotic effect of heme oxygenase-1 in endothelial cells involves the degradation of p38 alpha MAPK isoform
    • Silva G, Cunha A, Gregoire IP, Seldon MP, and Soares MP. The antiapoptotic effect of heme oxygenase-1 in endothelial cells involves the degradation of p38 alpha MAPK isoform. J Immunol 177: 1894-1903, 2006.
    • (2006) J Immunol , vol.177 , pp. 1894-1903
    • Silva, G.1    Cunha, A.2    Gregoire, I.P.3    Seldon, M.P.4    Soares, M.P.5
  • 160
    • 77957602846 scopus 로고    scopus 로고
    • CORMs protect endothelial cells during cold preservation, resulting in inhibition of intimal hyperplasia after aorta transplantation in rats
    • Song H, Hoeger S, Hillebrands JL, Mandel I, Loesel R, Beck G, Schilling L, Schnuelle P, and Yard B. CORMs protect endothelial cells during cold preservation, resulting in inhibition of intimal hyperplasia after aorta transplantation in rats. Transpl Int 23: 1144-1153, 2010.
    • (2010) Transpl Int , vol.23 , pp. 1144-1153
    • Song, H.1    Hoeger, S.2    Hillebrands, J.L.3    Mandel, I.4    Loesel, R.5    Beck, G.6    Schilling, L.7    Schnuelle, P.8    Yard, B.9
  • 162
    • 33750969074 scopus 로고    scopus 로고
    • Heme oxygenase-1: A novel drug target for atherosclerotic diseases?
    • Stocker R and Perrella MA. Heme oxygenase-1: a novel drug target for atherosclerotic diseases? Circulation 114: 2178-2189, 2006.
    • (2006) Circulation , vol.114 , pp. 2178-2189
    • Stocker, R.1    Ma, P.2
  • 163
    • 0028228808 scopus 로고
    • Soluble guanylate cyclase from bovine lung: Activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states
    • Stone JR and Marletta MA. Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states. Biochemistry 33: 5636-5640, 1994.
    • (1994) Biochemistry , vol.33 , pp. 5636-5640
    • Stone, J.R.1    Marletta, M.A.2
  • 164
    • 78649357701 scopus 로고    scopus 로고
    • Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells
    • Sukumari-Ramesh S, Laird MD, Singh N, Vender JR, Al-leyne CH, Jr., and Dhandapani KM. Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells. Glia 58: 1858-1870, 2010.
    • (2010) Glia , vol.58 , pp. 1858-1870
    • Sukumari-Ramesh, S.1    Laird, M.D.2    Singh, N.3    Vender, J.R.4    Al-leyne Jr., C.H.5    Dhandapani, K.M.6
  • 165
    • 50249117105 scopus 로고    scopus 로고
    • Preconditioning of carbon monoxide releasing molecule-derived CO attenuates LPS-induced activation of HUVEC
    • Sun B, Zou X, Chen Y, Zhang P, and Shi G. Preconditioning of carbon monoxide releasing molecule-derived CO attenuates LPS-induced activation of HUVEC. Int J Biol Sci 4: 270-278, 2008.
    • (2008) Int J Biol Sci , vol.4 , pp. 270-278
    • Sun, B.1    Zou, X.2    Chen, Y.3    Zhang, P.4    Shi, G.5
  • 168
    • 0042163205 scopus 로고    scopus 로고
    • Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes
    • Hoen PA, Van der Lans CA, Van Eck M, Bijsterbosch MK, Van Berkel TJ, and Twisk J. Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes. Circ Res 93: 262-269, 2003.
    • (2003) Circ Res , vol.93 , pp. 262-269
    • Hoen, P.A.1    Van Der Lans, C.A.2    Van Eck, M.3    Bijsterbosch, M.K.4    Van Berkel, T.J.5    Twisk, J.6
  • 170
    • 27744505661 scopus 로고    scopus 로고
    • Improved graft mesenchymal stem cell survival in is-chemic heart with a hypoxia-regulated heme oxygenase-1 vector
    • Tang YL, Tang Y, Zhang YC, Qian K, Shen L, and Phillips MI. Improved graft mesenchymal stem cell survival in is-chemic heart with a hypoxia-regulated heme oxygenase-1 vector. J Am Coll Cardiol 46: 1339-1350, 2005.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1339-1350
    • Tang, Y.L.1    Tang, Y.2    Zhang, Y.C.3    Qian, K.4    Shen, L.5    Phillips, M.I.6
  • 171
    • 0032993141 scopus 로고    scopus 로고
    • TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells
    • Terry CM, Clikeman JA, Hoidal JR, and Callahan KS. TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells. Am J Physiol 276: H1493-H1501, 1999.
    • (1999) Am J Physiol , vol.276
    • Terry, C.M.1    Clikeman, J.A.2    Hoidal, J.R.3    Callahan, K.S.4
  • 172
    • 0033372937 scopus 로고    scopus 로고
    • Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS
    • Thorup C, Jones CL, Gross SS, Moore LC, and Goligorsky MS. Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS. Am J Physiol 277: F882-F889, 1999.
    • (1999) Am J Physiol , vol.277
    • Thorup, C.1    Jones, C.L.2    Gross, S.S.3    Moore, L.C.4    Goligorsky, M.S.5
  • 176
    • 33748521847 scopus 로고    scopus 로고
    • Sildenafil induces angiogenic response in human coronary arteriolar endothelial cells through the expression of thioredoxin, hemeoxygenase and vascular endothelial growth factor
    • Vidavalur R, Penumathsa SV, Zhan L, Thirunavukkarasu M, and Maulik N. Sildenafil induces angiogenic response in human coronary arteriolar endothelial cells through the expression of thioredoxin, hemeoxygenase and vascular endothelial growth factor. Vascul Pharmacol 45: 91-95, 2006.
    • (2006) Vascul Pharmacol , vol.45 , pp. 91-95
    • Vidavalur, R.1    Penumathsa, S.V.2    Zhan, L.3    Thirunavukkarasu, M.4    Maulik, N.5
  • 177
    • 0037448802 scopus 로고    scopus 로고
    • Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: Implications in the antiproliferative response to rapamycin
    • Visner GA, Lu F, Zhou H, Liu J, Kazemfar K, and Agarwal A. Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation 107: 911-916, 2003.
    • (2003) Circulation , vol.107 , pp. 911-916
    • Visner, G.A.1    Lu, F.2    Zhou, H.3    Liu, J.4    Kazemfar, K.5    Agarwal, A.6
  • 180
    • 0031935208 scopus 로고    scopus 로고
    • Expression of heme oxygenase-1 in atherosclerotic lesions
    • Wang LJ, Lee TS, Lee FY, Pai RC, and Chau LY. Expression of heme oxygenase-1 in atherosclerotic lesions. Am J Pathol 152: 711-720, 1998.
    • (1998) Am J Pathol , vol.152 , pp. 711-720
    • Wang, L.J.1    Lee, T.S.2    Lee, F.Y.3    Pai, R.C.4    Chau, L.Y.5
  • 181
    • 33847291917 scopus 로고    scopus 로고
    • Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation
    • Wang X, Wang Y, Kim HP, Nakahira K, Ryter SW, and Choi AM. Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation. J Biol Chem 282: 1718-1726, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 1718-1726
    • Wang, X.1    Wang, Y.2    Kim, H.P.3    Nakahira, K.4    Ryter, S.W.5    Choi, A.M.6
  • 185
    • 84871713925 scopus 로고    scopus 로고
    • The social network of carbon monoxide in medicine
    • Wegiel B, Hanto DW, and Otterbein LE. The social network of carbon monoxide in medicine. Trends Mol Med 19: 3-11, 2013.
    • (2013) Trends Mol Med , vol.19 , pp. 3-11
    • Wegiel, B.1    Hanto, D.W.2    Otterbein, L.E.3
  • 186
    • 77951770043 scopus 로고    scopus 로고
    • Carbon monoxide-releasing molecule-2 (CORM-2) attenuates acute hepatic ischemia reperfusion injury in rats
    • Wei Y, Chen P, de Bruyn M, Zhang W, Bremer E, and Helfrich W. Carbon monoxide-releasing molecule-2 (CORM-2) attenuates acute hepatic ischemia reperfusion injury in rats. BMC Gastroenterol 10: 42, 2010.
    • BMC Gastroenterol , vol.10 , Issue.42 , pp. 2010
    • Wei, Y.1    Chen, P.2    De Bruyn, M.3    Zhang, W.4    Bremer, E.5    Helfrich, W.6
  • 189
    • 84855381655 scopus 로고    scopus 로고
    • Niacin Inhibits Vascular Inflammation via the Induction of Heme Oxyge-nase-1
    • Wu BJ, Chen K, Barter PJ, and Rye KA. Niacin Inhibits Vascular Inflammation via the Induction of Heme Oxyge-nase-1. Circulation 125: 150-158, 2012.
    • (2012) Circulation , vol.125 , pp. 150-158
    • Wu, B.J.1    Chen, K.2    Barter, P.J.3    Rye, K.A.4
  • 192
    • 33646179260 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways
    • Wu CC, Hsu MC, Hsieh CW, Lin JB, Lai PH, and Wung BS. Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways. Life Sci 78: 2889-2897, 2006.
    • (2006) Life Sci , vol.78 , pp. 2889-2897
    • Wu, C.C.1    Hsu, M.C.2    Hsieh, C.W.3    Lin, J.B.4    Lai, P.H.5    Wung, B.S.6
  • 193
    • 27744523788 scopus 로고    scopus 로고
    • Bilirubin derived from heme degradation suppresses MHC class II expression in endothelial cells
    • Wu J, Ma J, Fan ST, Schlitt HJ, and Tsui TY. Bilirubin derived from heme degradation suppresses MHC class II expression in endothelial cells. Biochem Biophys Res Commun 338: 890-896, 2005.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 890-896
    • Wu, J.1    Ma, J.2    Fan, S.T.3    Schlitt, H.J.4    Tsui, T.Y.5
  • 196
    • 0141706806 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling
    • Yet SF, Layne MD, Liu X, Chen YH, Ith B, Sibinga NE, and Perrella MA. Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling. FASEB J 17: 1759-1761, 2003.
    • (2003) FASEB J , vol.17 , pp. 1759-1761
    • Yet, S.F.1    Layne, M.D.2    Liu, X.3    Chen, Y.H.4    Ith, B.5    Sibinga, N.E.6    Perrella, M.A.7
  • 199
    • 33845679333 scopus 로고    scopus 로고
    • Endothelial STAT3 is essential for the protective effects of HO-1 in oxidant-induced lung injury
    • Zhang X, Shan P, Jiang G, Zhang SS, Otterbein LE, Fu XY, and Lee PJ. Endothelial STAT3 is essential for the protective effects of HO-1 in oxidant-induced lung injury. FASEB J 20: 2156-2158, 2006.
    • (2006) FASEB J , vol.20 , pp. 2156-2158
    • Zhang, X.1    Shan, P.2    Jiang, G.3    Zhang, S.S.4    Otterbein, L.E.5    Fu, X.Y.6    Lee, P.J.7
  • 200
    • 0037428458 scopus 로고    scopus 로고
    • Carbon monoxide inhibition of apo-ptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3
    • Zhang X, Shan P, Otterbein LE, Alam J, Flavell RA, Davis RJ, Choi AM, and Lee PJ. Carbon monoxide inhibition of apo-ptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. J Biol Chem 278: 1248-1258, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 1248-1258
    • Zhang, X.1    Shan, P.2    Otterbein, L.E.3    Alam, J.4    Flavell, R.A.5    Davis, R.J.6    Choi, A.M.7    Lee, P.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.