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Volumn 331, Issue 3, 2009, Pages 925-932

Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CYTOKINE; HEME OXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SN 50; SUPEROXIDE; VASCULOTROPIN RECEPTOR 1; HEME OXYGENASE; HEME OXYGENASE-2; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

EID: 73349117810     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.158352     Document Type: Article
Times cited : (53)

References (35)
  • 1
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Abraham NG and Kappas A (2008) Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev 60:79-127.
    • (2008) Pharmacol Rev , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 3
    • 50849094843 scopus 로고    scopus 로고
    • Exacerbated corneal inflammation and neovascularization in the HO-2 null mice is ameliorated by biliverdin
    • Bellner L, Vitto M, Patil KA, Dunn MW, Regan R, and Laniado-Schwartzman M (2008) Exacerbated corneal inflammation and neovascularization in the HO-2 null mice is ameliorated by biliverdin. Exp Eye Res 87:268-278.
    • (2008) Exp Eye Res , vol.87 , pp. 268-278
    • Bellner, L.1    Vitto, M.2    Patil, K.A.3    Dunn, M.W.4    Regan, R.5    Laniado-Schwartzman, M.6
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 1642581763 scopus 로고    scopus 로고
    • Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: Induction of angiogenesis and inhibition of leukocytic infiltration
    • Bussolati B, Ahmed A, Pemberton H, Landis RC, Di Carlo F, Haskard DO, and Mason JC (2004) Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration. Blood 103:761-766.
    • (2004) Blood , vol.103 , pp. 761-766
    • Bussolati, B.1    Ahmed, A.2    Pemberton, H.3    Landis, R.C.4    Di Carlo, F.5    Haskard, D.O.6    Mason, J.C.7
  • 6
    • 1642368362 scopus 로고    scopus 로고
    • Induction of cytoprotective genes through Nrf2/ antioxidant response element pathway: A new therapeutic approach for the treatment of inflammatory diseases
    • Chen XL and Kunsch C (2004) Induction of cytoprotective genes through Nrf2/ antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases. Curr Pharm Des 10:879-891.
    • (2004) Curr Pharm Des , vol.10 , pp. 879-891
    • Chen, X.L.1    Kunsch, C.2
  • 7
    • 60749137151 scopus 로고    scopus 로고
    • NADPH oxidase-dependent signaling in endothelial cells: Role in physiology and pathophysiology
    • Frey RS, Ushio-Fukai M, and Malik A (2009) NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal 11:791-810.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 791-810
    • Frey, R.S.1    Ushio-Fukai, M.2    Malik, A.3
  • 8
    • 35648987863 scopus 로고    scopus 로고
    • Biliverdin inhibits activation of NF-kappaB: Reversal of inhibition by human biliverdin reductase
    • Gibbs PE and Maines MD (2007) Biliverdin inhibits activation of NF-kappaB: reversal of inhibition by human biliverdin reductase. Int J Cancer 121:2567-2574.
    • (2007) Int J Cancer , vol.121 , pp. 2567-2574
    • Gibbs, P.E.1    Maines, M.D.2
  • 9
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources , 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC
    • Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
    • (1996) Guide for the Care and Use of Laboratory Animals
  • 10
    • 37349011542 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-kappaB activation and the production of inflammatory cytokines in human endothelial cells
    • Ishizuka T, Cheng J, Singh H, Vitto MD, Manthati VL, Falck JR, and Laniado-Schwartzman M (2008) 20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-kappaB activation and the production of inflammatory cytokines in human endothelial cells. J Pharmacol Exp Ther 324:103-110.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 103-110
    • Ishizuka, T.1    Cheng, J.2    Singh, H.3    Vitto, M.D.4    Manthati, V.L.5    Falck, J.R.6    Laniado-Schwartzman, M.7
  • 14
    • 34547135735 scopus 로고    scopus 로고
    • Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress
    • Lin Q, Weis S, Yang G, Weng YH, Helston R, Rish K, Smith A, Bordner J, Polte T, Gaunitz F, et al. (2007) Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress. J Biol Chem 282: 20621-20633.
    • (2007) J Biol Chem , vol.282 , pp. 20621-20633
    • Lin, Q.1    Weis, S.2    Yang, G.3    Weng, Y.H.4    Helston, R.5    Rish, K.6    Smith, A.7    Bordner, J.8    Polte, T.9    Gaunitz, F.10
  • 16
    • 0023731036 scopus 로고
    • Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
    • Maines MD (1988) Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2:2557-2568.
    • (1988) FASEB J , vol.2 , pp. 2557-2568
    • Maines, M.D.1
  • 17
    • 0037166355 scopus 로고    scopus 로고
    • Eicosanoid regulation of vascular endothelial growth factor expression and angiogenesis in microvessel endothelial cells
    • Mezentsev A, Seta F, Dunn MW, Ono N, Falck JR, and Laniado-Schwartzman M (2002) Eicosanoid regulation of vascular endothelial growth factor expression and angiogenesis in microvessel endothelial cells. J Biol Chem 277:18670-18676.
    • (2002) J Biol Chem , vol.277 , pp. 18670-18676
    • Mezentsev, A.1    Seta, F.2    Dunn, M.W.3    Ono, N.4    Falck, J.R.5    Laniado-Schwartzman, M.6
  • 19
    • 0033847184 scopus 로고    scopus 로고
    • The indispensability of heme oxygenase-1 in protecting against acute heme proteininduced toxicity in vivo
    • Nath KA, Haggard JJ, Croatt AJ, Grande JP, Poss KD, and Alam J (2000) The indispensability of heme oxygenase-1 in protecting against acute heme proteininduced toxicity in vivo. Am J Pathol 156:1527-1535.
    • (2000) Am J Pathol , vol.156 , pp. 1527-1535
    • Nath, K.A.1    Haggard, J.J.2    Croatt, A.J.3    Grande, J.P.4    Poss, K.D.5    Alam, J.6
  • 22
    • 34249789273 scopus 로고    scopus 로고
    • Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase
    • Peshavariya HM, Dusting GJ, and Selemidis S (2007) Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase. Free Radic Res 41:699-712.
    • (2007) Free Radic Res , vol.41 , pp. 699-712
    • Peshavariya, H.M.1    Dusting, G.J.2    Selemidis, S.3
  • 23
    • 0028880959 scopus 로고
    • Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice
    • Poss KD, Thomas MJ, Ebralidze AK, O'Dell TJ, and Tonegawa S (1995) Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice. Neuron 15: 867-873.
    • (1995) Neuron , vol.15 , pp. 867-873
    • Poss, K.D.1    Thomas, M.J.2    Ebralidze, A.K.3    O'Dell, T.J.4    Tonegawa, S.5
  • 24
    • 0141749478 scopus 로고    scopus 로고
    • Heme oxygenase-2 knockout neurons are less vulnerable to hemoglobin toxicity
    • Rogers B, Yakopson V, Teng ZP, Guo Y, and Regan RF (2003) Heme oxygenase-2 knockout neurons are less vulnerable to hemoglobin toxicity. Free Radic Biol Med 35:872-881.
    • (2003) Free Radic Biol Med , vol.35 , pp. 872-881
    • Rogers, B.1    Yakopson, V.2    Teng, Z.P.3    Guo, Y.4    Regan, R.F.5
  • 27
    • 33750842076 scopus 로고    scopus 로고
    • Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis
    • Shibuya M (2006a) Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. J Biochem Mol Biol 39:469-478.
    • (2006) J Biochem Mol Biol , vol.39 , pp. 469-478
    • Shibuya, M.1
  • 28
    • 34447310236 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): A dual regulator for angiogenesis
    • discussion 231
    • Shibuya M (2006b) Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. Angiogenesis 9:225-230, discussion 231.
    • (2006) Angiogenesis , vol.9 , pp. 225-230
    • Shibuya, M.1
  • 29
    • 0023132858 scopus 로고
    • Bilirubin is an antioxidant of possible physiological importance
    • Stocker R, Yamamoto Y, McDonagh AF, Glazer AN, and Ames BN (1987) Bilirubin is an antioxidant of possible physiological importance. Science 235:1043-1046.
    • (1987) Science , vol.235 , pp. 1043-1046
    • Stocker, R.1    Yamamoto, Y.2    McDonagh, A.F.3    Glazer, A.N.4    Ames, B.N.5
  • 30
    • 0029664452 scopus 로고    scopus 로고
    • The role of NFkappaB in the angiogenic response of coronary microvessel endothelial cells
    • Stoltz RA, Abraham NG, and Laniado-Schwartzman M (1996) The role of NFkappaB in the angiogenic response of coronary microvessel endothelial cells. Proc Natl Acad Sci U S A 93:2832-2837.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2832-2837
    • Stoltz, R.A.1    Abraham, N.G.2    Laniado-Schwartzman, M.3
  • 31
    • 41049097824 scopus 로고    scopus 로고
    • NF-kappa B: A new player in angiostatic therapy
    • Tabruyn SP and Griffioen AW (2008) NF-kappa B: a new player in angiostatic therapy. Angiogenesis 11:101-106.
    • (2008) Angiogenesis , vol.11 , pp. 101-106
    • Tabruyn, S.P.1    Griffioen, A.W.2
  • 33
    • 34249071326 scopus 로고    scopus 로고
    • VEGF signaling through NADPH oxidase-derived ROS
    • Ushio-Fukai M (2007) VEGF signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal 9:731-739.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 731-739
    • Ushio-Fukai, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.