Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection

Circulation Research

Volumn 110, Issue 1, 2012, Pages 20-33

  Boyle, Joseph J ^a   Johns, Michael ^a   Kampfer, Theresa ^a,b   Nguyen, Aivi T ^a   Game, Laurence ^c   Schaer, Dominik J ^a,b   Mason, Justin C ^a   Haskard, Dorian O ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

activating transcription factor 1; atherosclerosis; heme oxygenase 1; lipids; macrophages

Indexed keywords

ABC TRANSPORTER A1; ACTIVATING TRANSCRIPTION FACTOR 1; CHOLESTEROL; HEME; HEME OXYGENASE 1; IRON; LIVER X RECEPTOR BETA; SMALL INTERFERING RNA;

ARTICLE; ATHEROSCLEROTIC PLAQUE; BIOINFORMATICS; BLEEDING; CELL STIMULATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENHANCER REGION; FOAM CELL; GENE CONTROL; GENE INDUCTION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HEMORRHAGE SPECIALIST MACROPHAGE; HUMAN; HUMAN CELL; MACROPHAGE; MICROARRAY ANALYSIS; MONOCYTE; NORMAL HUMAN; OXIDATIVE STRESS; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ACTIVATING TRANSCRIPTION FACTOR 1; ATP-BINDING CASSETTE TRANSPORTERS; CELL COMMUNICATION; CELLS, CULTURED; FOAM CELLS; HEME; HEME OXYGENASE-1; HEMORRHAGE; HUMANS; IRON; LIPID METABOLISM; MACROPHAGES; ORPHAN NUCLEAR RECEPTORS; OXIDATIVE STRESS; PLAQUE, ATHEROSCLEROTIC; SIGNAL TRANSDUCTION;

EID: 84855348346     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.247577     Document Type: Article

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