PPARσ and PGC1α act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress

Cardiovascular Research

Volumn 85, Issue 4, 2010, Pages 701-710

  Ali, Faisal ^a   Ali, Nadira S ^a   Bauer, Andrea ^a   Boyle, Joseph J ^a   Hamdulay, Shahir S ^a   Haskard, Dorian O ^a   Randi, Anna M ^a   Mason, Justin C ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Endothelium; Haem oxygenase 1; Nuclear receptors; Oxidative stress; Peroxisome proliferator activated receptors

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; HEME OXYGENASE 1; HYDROGEN PEROXIDE; LEPTIN; MESSENGER RNA; OXIDIZING AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SMALL INTERFERING RNA; HEAT SHOCK PROTEIN; LIGAND; PPARGC1A PROTEIN, HUMAN; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; AORTA; ARTICLE; ATHEROGENESIS; BINDING SITE; CELL PROTECTION; CELL STRESS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; FEEDBACK SYSTEM; GENE; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INJURY; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM; VASCULARIZATION; ANIMAL; APOPTOSIS; ATHEROSCLEROSIS; C57BL MOUSE; CELL CULTURE; CYTOLOGY; ENZYME ACTIVATION; GENETICS; HOMEOSTASIS; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; TRANSCRIPTION INITIATION; UMBILICAL VEIN;

ANIMALS; AORTA; APOPTOSIS; ATHEROSCLEROSIS; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FEEDBACK, PHYSIOLOGICAL; HEAT-SHOCK PROTEINS; HEME OXYGENASE-1; HOMEOSTASIS; HUMANS; LIGANDS; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PPAR DELTA; RNA, SMALL INTERFERING; THIAZOLES; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UMBILICAL VEINS;

EID: 76749083354     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp365     Document Type: Article

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