Sildenafil stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells via distinct signaling pathways

Biochemical Pharmacology

Volumn 84, Issue 8, 2012, Pages 1045-1054

  Liu, Xiao Ming ^a   Peyton, Kelly J ^a   Wang, Xinhui ^a   Durante, William ^a  

^a University of Missouri   (United States)

Author keywords

Heme oxygenase; Inducible nitric oxide synthase; Vascular smooth muscle cells

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ACETYLCYSTEINE; CARBON MONOXIDE; GUANYLATE CYCLASE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; KT 5720; KT 5823; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; ROTENONE; SILDENAFIL; TRANSCRIPTION FACTOR NF E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE OVEREXPRESSION; MUTANT; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SYNTHESIS; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARBON MONOXIDE; CELLS, CULTURED; HEME OXYGENASE (DECYCLIZING); MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PHOSPHODIESTERASE 5 INHIBITORS; PIPERAZINES; PROMOTER REGIONS, GENETIC; PURINES; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SULFONES; VASODILATOR AGENTS;

EID: 84866128524     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.07.023     Document Type: Article

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