-
1
-
-
0030921166
-
Protective genes expressed in endothelial cells: A regulatory response to injury
-
Bach FH, Hancock WW, Ferran C. Protective genes expressed in endothelial cells: a regulatory response to injury. Immunol Today. 1997;18:483-486.
-
(1997)
Immunol Today
, vol.18
, pp. 483-486
-
-
Bach, F.H.1
Hancock, W.W.2
Ferran, C.3
-
2
-
-
0034979275
-
Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
-
Zachary I. Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor. Am J Physiol Cell Physiol. 2001; 280:C1375-C1386.
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Zachary, I.1
-
3
-
-
1642581763
-
Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: Induction of angiogenesis and inhibition of leukocytic infiltration
-
Bussolati B, Ahmed A, Pemberton H, et al. Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration. Blood. 2004;103: 761-766.
-
(2004)
Blood
, vol.103
, pp. 761-766
-
-
Bussolati, B.1
Ahmed, A.2
Pemberton, H.3
-
4
-
-
4744342973
-
Decay-accelerating factor induction on vascular endothelium by VEGF is mediated via a VEGF-R2 and PKCα/ε-dependent cytoprotective signaling pathway and is inhibited by cyclosporin A
-
Mason JC, Steinberg R, Lidington EA, Kinderlerer AR, Ohba M, Haskard DO. Decay-accelerating factor induction on vascular endothelium by VEGF is mediated via a VEGF-R2 and PKCα/ε-dependent cytoprotective signaling pathway and is inhibited by cyclosporin A. J Biol Chem. 2004; 279:41611-41618.
-
(2004)
J Biol Chem
, vol.279
, pp. 41611-41618
-
-
Mason, J.C.1
Steinberg, R.2
Lidington, E.A.3
Kinderlerer, A.R.4
Ohba, M.5
Haskard, D.O.6
-
5
-
-
0014348401
-
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
-
Tenhunen R, Marver HS, Schmid R. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci U S A. 1968;61:748-755.
-
(1968)
Proc Natl Acad Sci U S A
, vol.61
, pp. 748-755
-
-
Tenhunen, R.1
Marver, H.S.2
Schmid, R.3
-
6
-
-
0025969686
-
Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron
-
Eisenstein RS, Garcia-Mayol D, Pettingell W, Munro HN. Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. Proc Natl Acad Sci U S A. 1991;88: 688-692.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 688-692
-
-
Eisenstein, R.S.1
Garcia-Mayol, D.2
Pettingell, W.3
Munro, H.N.4
-
7
-
-
0033161957
-
Haem oxygenase-1 prevents cell death by regulating cellular iron
-
Ferris CD, Jaffrey SR, Sawa A, et al. Haem oxygenase-1 prevents cell death by regulating cellular iron. Nat Cell Biol. 1999;1:152-157.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 152-157
-
-
Ferris, C.D.1
Jaffrey, S.R.2
Sawa, A.3
-
8
-
-
0032893958
-
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
-
Yachie A, Niida Y, Wada T, et al. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J Clin Invest. 1999;103:129-135.
-
(1999)
J Clin Invest
, vol.103
, pp. 129-135
-
-
Yachie, A.1
Niida, Y.2
Wada, T.3
-
9
-
-
0030886381
-
Heme oxygenase 1 is required for mammalian iron reutilization
-
Poss KD, Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci U S A. 1997;94:10919-10924.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10919-10924
-
-
Poss, K.D.1
Tonegawa, S.2
-
10
-
-
0035896220
-
Heme oxygenase-1 inhibits atherosclerotic lesion formation in LDL-receptor knockout mice
-
Ishikawa K, Sugawara D, Wang Xp, et al. Heme oxygenase-1 inhibits atherosclerotic lesion formation in LDL-receptor knockout mice. Circ Res. 2001;88:506-512.
-
(2001)
Circ Res
, vol.88
, pp. 506-512
-
-
Ishikawa, K.1
Sugawara, D.2
Wang, X.3
-
11
-
-
0035920256
-
Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice
-
Yet S-F, Tian R, Layne MD, et al. Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Circ Res. 2001;89:168-173.
-
(2001)
Circ Res
, vol.89
, pp. 168-173
-
-
Yet, S.-F.1
Tian, R.2
Layne, M.D.3
-
12
-
-
0031757984
-
Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes
-
Hancock WW, Buelow R, Sayegh MH, Turka LA. Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes. Nat Med. 1998;4:1392-1396.
-
(1998)
Nat Med
, vol.4
, pp. 1392-1396
-
-
Hancock, W.W.1
Buelow, R.2
Sayegh, M.H.3
Turka, L.A.4
-
13
-
-
0031697123
-
Expression of heme oxygenase-1 can determine cardiac xenograft survival
-
Soares MP, Lin Y, Anrather J, et al. Expression of heme oxygenase-1 can determine cardiac xenograft survival. Nat Med. 1998;4:1073-1077.
-
(1998)
Nat Med
, vol.4
, pp. 1073-1077
-
-
Soares, M.P.1
Lin, Y.2
Anrather, J.3
-
14
-
-
0344284580
-
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury
-
Otterbein LE, Zuckerbraun BS, Haga M, et al. Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med. 2003;9:183-190.
-
(2003)
Nat Med
, vol.9
, pp. 183-190
-
-
Otterbein, L.E.1
Zuckerbraun, B.S.2
Haga, M.3
-
15
-
-
0028881851
-
Complement-mediated regulation of tissue factor activity in endothelium
-
Saadi S, Holzknecht RA, Patte CP, Stern DM, Platt JL. Complement-mediated regulation of tissue factor activity in endothelium. J Exp Med. 1995;182:1807-1814.
-
(1995)
J Exp Med
, vol.182
, pp. 1807-1814
-
-
Saadi, S.1
Holzknecht, R.A.2
Patte, C.P.3
Stern, D.M.4
Platt, J.L.5
-
16
-
-
0031010642
-
The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity
-
Tedesco F, Pausa M, Nardon E, Introna M, Mantovani A, Dobrina A. The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity. J Exp Med. 1997; 185:1619-1627.
-
(1997)
J Exp Med
, vol.185
, pp. 1619-1627
-
-
Tedesco, F.1
Pausa, M.2
Nardon, E.3
Introna, M.4
Mantovani, A.5
Dobrina, A.6
-
17
-
-
0024334289
-
Decay-accelerating factor: Biochemistry, molecular biology and function
-
Lublin DM, Atkinson JP. Decay-accelerating factor: biochemistry, molecular biology and function. Annu Rev Immunol. 1989;7:35-58.
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 35-58
-
-
Lublin, D.M.1
Atkinson, J.P.2
-
18
-
-
0033198618
-
Induction of decay-accelerating factor by cytokines or the membrane-attack complex protects vascular endothelial cells against complement deposition
-
Mason JC, Yarwood H, Sugars K, Morgan BP, Davies KA, Haskard DO. Induction of decay-accelerating factor by cytokines or the membrane-attack complex protects vascular endothelial cells against complement deposition. Blood. 1999;94: 1673-1682.
-
(1999)
Blood
, vol.94
, pp. 1673-1682
-
-
Mason, J.C.1
Yarwood, H.2
Sugars, K.3
Morgan, B.P.4
Davies, K.A.5
Haskard, D.O.6
-
19
-
-
1542619241
-
Critical protection from renal ischemia reperfusion injury by CD55 and CD59
-
Yamada K, Miwa T, Liu J, Nangaku M, Song W-C. Critical protection from renal ischemia reperfusion injury by CD55 and CD59. J Immunol. 2004;172: 3869-3875.
-
(2004)
J Immunol
, vol.172
, pp. 3869-3875
-
-
Yamada, K.1
Miwa, T.2
Liu, J.3
Nangaku, M.4
Song, W.-C.5
-
20
-
-
0036127426
-
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
-
Lee TS, Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med. 2002;8:240-246.
-
(2002)
Nat Med
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
-
21
-
-
0037448802
-
Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: Implications in the antiproliferative response to rapamycin
-
Visner GA, Lu F, Zhou H, Liu J, Kazemfar K, Agarwal A. Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation. 2003;107:911-916.
-
(2003)
Circulation
, vol.107
, pp. 911-916
-
-
Visner, G.A.1
Lu, F.2
Zhou, H.3
Liu, J.4
Kazemfar, K.5
Agarwal, A.6
-
22
-
-
23444454955
-
Heme oxygenase-1: A therapeutic amplification funnel
-
Bach FH. Heme oxygenase-1: a therapeutic amplification funnel. FASEB J. 2005;19:1216-1219.
-
(2005)
FASEB J
, vol.19
, pp. 1216-1219
-
-
Bach, F.H.1
-
23
-
-
0036090780
-
Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells
-
Dulak J, Jozkowicz A, Foresti R, et al. Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells. Antioxid Redox Signal. 2002;4:229-240.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 229-240
-
-
Dulak, J.1
Jozkowicz, A.2
Foresti, R.3
-
24
-
-
0027452195
-
A beneficial role of bile pigments as an endogenous tissue protector: Anti-complement effects of biliverdin and conjugated bilirubin
-
Nakagami T, Toyomura K, Kinoshita T, Morisawa S. A beneficial role of bile pigments as an endogenous tissue protector: anti-complement effects of biliverdin and conjugated bilirubin. Biochim Biophys Acta. 1993;1158:189-193.
-
(1993)
Biochim Biophys Acta
, vol.1158
, pp. 189-193
-
-
Nakagami, T.1
Toyomura, K.2
Kinoshita, T.3
Morisawa, S.4
-
25
-
-
0030045835
-
Heme oxygenase: A novel target for the modulation of the inflammatory response
-
Willis D, Moore AR, Frederick R, Willoughby DA. Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat Med. 1996;2:87-90.
-
(1996)
Nat Med
, vol.2
, pp. 87-90
-
-
Willis, D.1
Moore, A.R.2
Frederick, R.3
Willoughby, D.A.4
-
26
-
-
0033561224
-
Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice
-
Yet SF, Perrella MA, Layne MD, et al. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest. 1999;103:R23-R99.
-
(1999)
J Clin Invest
, vol.103
-
-
Yet, S.F.1
Perrella, M.A.2
Layne, M.D.3
-
27
-
-
0034693434
-
Isolation of endothelial cells from murine tissue
-
Marelli-Berg FM, Peek E, Lidington EA, Stauss HJ, Lechler RI. Isolation of endothelial cells from murine tissue. J Immunol Methods. 2000;244: 205-215.
-
(2000)
J Immunol Methods
, vol.244
, pp. 205-215
-
-
Marelli-Berg, F.M.1
Peek, E.2
Lidington, E.A.3
Stauss, H.J.4
Lechler, R.I.5
-
28
-
-
38849203158
-
Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276
-
Seldon MP, Silva G, Pejanovic N, et al. Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276. J Immunol. 2007;179:7840-7851.
-
(2007)
J Immunol
, vol.179
, pp. 7840-7851
-
-
Seldon, M.P.1
Silva, G.2
Pejanovic, N.3
-
29
-
-
0034071424
-
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
-
Otterbein LE, Bach FH, Alam J, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med. 2000;6:422-428.
-
(2000)
Nat Med
, vol.6
, pp. 422-428
-
-
Otterbein, L.E.1
Bach, F.H.2
Alam, J.3
-
30
-
-
34250008488
-
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
-
Pamplona A, Ferreira A, Balla J, et al. Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat Med. 2007;13:703-710.
-
(2007)
Nat Med
, vol.13
, pp. 703-710
-
-
Pamplona, A.1
Ferreira, A.2
Balla, J.3
-
31
-
-
1542724430
-
Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation
-
Soares MP, Seldon MP, Gregoire IP, et al. Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation. J Immunol. 2004;172:3553-3563.
-
(2004)
J Immunol
, vol.172
, pp. 3553-3563
-
-
Soares, M.P.1
Seldon, M.P.2
Gregoire, I.P.3
-
32
-
-
36349008676
-
Statin-mediated cytoprotection of human vascular endothelial cells: A role for Kruppel-like factor 2-dependent induction of heme oxygenase-1
-
Ali F, Hamdulay SH, Kinderlerer AR, et al. Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1. J Thromb Haemost. 2007;5:2537-2546.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2537-2546
-
-
Ali, F.1
Hamdulay, S.H.2
Kinderlerer, A.R.3
-
33
-
-
12844255778
-
Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer
-
Holla VR, Wang D, Brown JR, Mann JR, Katkuri S, DuBois RN. Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer. J Biol Chem. 2005; 280:476-483.
-
(2005)
J Biol Chem
, vol.280
, pp. 476-483
-
-
Holla, V.R.1
Wang, D.2
Brown, J.R.3
Mann, J.R.4
Katkuri, S.5
DuBois, R.N.6
-
34
-
-
0034596874
-
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis
-
Brouard S, Otterbein LE, Anrather J, et al. Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med. 2000;192:1015-1026.
-
(2000)
J Exp Med
, vol.192
, pp. 1015-1026
-
-
Brouard, S.1
Otterbein, L.E.2
Anrather, J.3
-
35
-
-
33645945014
-
Heme oxygenase-1/ carbon monoxide: From basic science to therapeutic applications
-
Ryter SW, Alam J, Choi AM. Heme oxygenase-1/ carbon monoxide: from basic science to therapeutic applications. Physiol Rev. 2006;86:583-650.
-
(2006)
Physiol Rev
, vol.86
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
36
-
-
0037208589
-
Phase II, randomized trial comparing bevaci-zumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al. Phase II, randomized trial comparing bevaci-zumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol. 2003;21:60-65.
-
(2003)
J Clin Oncol
, vol.21
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
-
37
-
-
34547941252
-
Autocrine VEGF signaling is required for vascular homeostasis
-
Lee S, Chen TT, Barber CL, et al. Autocrine VEGF signaling is required for vascular homeostasis. Cell. 2007;130:691-703.
-
(2007)
Cell
, vol.130
, pp. 691-703
-
-
Lee, S.1
Chen, T.T.2
Barber, C.L.3
-
38
-
-
47249112564
-
KLF-2-dependent, shear stress-induced expression of CD59: A novel cytoprotective mechanism against complement-mediated injury in the vasculature
-
Kinderlerer AR, Ali F, Johns M, et al. KLF-2-dependent, shear stress-induced expression of CD59: a novel cytoprotective mechanism against complement-mediated injury in the vasculature. J Biol Chem. 2008;283:14636- 14644.
-
(2008)
J Biol Chem
, vol.283
, pp. 14636-14644
-
-
Kinderlerer, A.R.1
Ali, F.2
Johns, M.3
-
39
-
-
0026750782
-
Superoxide responses of endothelial cells to C5a and TNF-α: Divergent signal transduction pathways
-
Murphy HS, Shayman JA, Till GO, et al. Superoxide responses of endothelial cells to C5a and TNF-α: divergent signal transduction pathways. Am J Physiol. 1992;263:L51-L59.
-
(1992)
Am J Physiol
, vol.263
-
-
Murphy, H.S.1
Shayman, J.A.2
Till, G.O.3
-
40
-
-
19944431852
-
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both
-
Nakao A, Neto JS, Kanno S, et al. Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant. 2005;5:282-291.
-
(2005)
Am J Transplant
, vol.5
, pp. 282-291
-
-
Nakao, A.1
Neto, J.S.2
Kanno, S.3
-
41
-
-
0032760050
-
Inhibitory effect of bilirubin on complement-mediated hemolysis
-
ArriagaSM, Mottino AD, AlmaraAM. Inhibitory effect of bilirubin on complement-mediated hemolysis. Biochim BiophysActa. 1999;1473:329-336.
-
(1999)
Biochim BiophysActa
, vol.1473
, pp. 329-336
-
-
Arriaga, S.M.1
Mottino, A.D.2
Almara, A.M.3
-
42
-
-
0035884632
-
-
Qian Z, Hu W, Liu J, Sanfilippo F, Hruban RH, Baldwin WM 3rd. Accelerated graft arteriosclerosis in cardiac transplants: complement activation promotes progression of lesions from medium to large arteries. Transplantation. 2001;72:900-906.
-
Qian Z, Hu W, Liu J, Sanfilippo F, Hruban RH, Baldwin WM 3rd. Accelerated graft arteriosclerosis in cardiac transplants: complement activation promotes progression of lesions from medium to large arteries. Transplantation. 2001;72:900-906.
-
-
-
-
43
-
-
33845883789
-
Inhibition of complement component C3 reduces vein graft atherosclerosis in apolipoprotein E3-Leiden transgenic mice
-
Schepers A, de Vries MR, van Leuven CJ, et al. Inhibition of complement component C3 reduces vein graft atherosclerosis in apolipoprotein E3-Leiden transgenic mice. Circulation. 2006;114: 2831-2838.
-
(2006)
Circulation
, vol.114
, pp. 2831-2838
-
-
Schepers, A.1
de Vries, M.R.2
van Leuven, C.J.3
-
44
-
-
0027358877
-
Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage
-
Balla J, Jacob HS, Balla G, Nath K, Eaton JW, Vercellotti GM. Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc Natl Acad Sci USA. 1993;90:9285-9289.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9285-9289
-
-
Balla, J.1
Jacob, H.S.2
Balla, G.3
Nath, K.4
Eaton, J.W.5
Vercellotti, G.M.6
-
45
-
-
33646238468
-
Heme oxygenase-1 is essential for and promotes tolerance to transplanted organs
-
YamashitaK, Ollinger R, McDaid J, et al. Heme oxygenase-1 is essential for and promotes tolerance to transplanted organs. FASEB J. 2006;20: 776-778.
-
(2006)
FASEB J
, vol.20
, pp. 776-778
-
-
Yamashita, K.1
Ollinger, R.2
McDaid, J.3
-
46
-
-
33846799062
-
-
Wehner J, Morrell CN, Reynolds T, Rodriguez ER, Baldwin WM 3rd. Antibody and complement in transplant vasculopathy. Circ Res. 2007;100: 191-203.
-
Wehner J, Morrell CN, Reynolds T, Rodriguez ER, Baldwin WM 3rd. Antibody and complement in transplant vasculopathy. Circ Res. 2007;100: 191-203.
-
-
-
-
47
-
-
34547686232
-
Heme oxygenase-1 in organ transplantation
-
Soares MP, Bach FH. Heme oxygenase-1 in organ transplantation. Front Biosci. 2007;12:4932-4945.
-
(2007)
Front Biosci
, vol.12
, pp. 4932-4945
-
-
Soares, M.P.1
Bach, F.H.2
-
49
-
-
0035039579
-
Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis
-
FujitaT, Toda K, KarimovaA, et al. Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis. Nat Med. 2001;7:598-604.
-
(2001)
Nat Med
, vol.7
, pp. 598-604
-
-
Fujita, T.1
Toda, K.2
Karimova, A.3
-
50
-
-
23844507814
-
Bilirubin: A natural inhibitor of vascular smooth muscle cell proliferation
-
Ollinger R, Bilban M, Erat A, et al. Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferation. Circulation. 2005;112:1030-1039.
-
(2005)
Circulation
, vol.112
, pp. 1030-1039
-
-
Ollinger, R.1
Bilban, M.2
Erat, A.3
|