Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells

Biochemical and Biophysical Research Communications

Volumn 402, Issue 1, 2010, Pages 99-104

  Ishikado, Atsushi ^a   Nishio, Yoshihiko ^a   Morino, Katsutaro ^a   Ugi, Satoshi ^a   Kondo, Hajime ^a   Makino, Taketoshi ^b   Kashiwagi, Atsunori ^a   Maegawa, Hiroshi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b Sunstar Inc   (Japan)

Author keywords

4 hydroxy hexenal; 4 hydroxy nonenal; N 3 polyunsaturated fatty acid; Oxidative stress; Peroxidation

Indexed keywords

HEME OXYGENASE 1; HEXOBARBITAL; MESSENGER RNA; OMEGA 3 FATTY ACID; SMALL INTERFERING RNA; TERT BUTYL HYDROPEROXIDE; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DOSE RESPONSE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION;

ALDEHYDES; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FATTY ACIDS, OMEGA-3; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HEME OXYGENASE-1; HUMANS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS;

EID: 78049269927     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.124     Document Type: Article

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