Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 277, Issue 6 21-6, 1999, Pages

  Hartsfield, Cynthia L ^a   Alam, Jawed ^b   Choi, Augustine M K ^c,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OCHSNER MEDICAL CENTER   (United States)

^c YALE UNIVERSITY   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activator protein 1; Endothelial cell; Heme oxygenase 1; Hypoxia inducible factor 1; Vascular smooth muscle cell

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; DNA; HEME OXYGENASE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DNA BINDING; ELECTROPHORETIC MOBILITY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYPOXIA; LUNG BLOOD VESSEL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PULMONARY ARTERY; RAT;

EID: 0033370832     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.6.l1133     Document Type: Article

References (38)

1. Alam, J., S. Camhi, and A. M. K. Choi. Identification of a second 5′ distal region that functions as a basal level and inducer-dependent transcriptional enhancer of the mouse heme oxygenase-1 gene. J. Biol. Chem. 270: 11977-11984, 1987.
2. Barberis, A., G. Superti-Furga, and M. Busslinger. Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter. Cell 50: 347-359, 1987.
3. Camhi, S., J. Alam, L. Otterbein, S. L. Sylvester, and A. M. K. Choi. Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. Am. J. Respir. Cell Mol. Biol. 13: 387-398, 1995.
4. Choi, A. M. K., and J. Alam. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am. J. Respir. Cell Mol. Biol. 15: 9-19, 1996.
5. Coceani, F., L. Kelsey, E. Seidlitz, G. S. Marks, B. E. McLaughlin, H. J. Vreman, D. K. Stevenson, M. Rabinovitch, and C. Ackerley. Carbon monoxide formation in the ductus arteriousus in the lamb: implications for the regulation of muscle tone. Br. J. Pharmacol. 102: 599-608, 1997.
6. Deng, W. P., and J. A. Nickoloff. Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal. Biochem. 200: 81-88, 1992.
7. Guillemin, K., and M. A. Krasnow. The hypoxic response: huffing and HIFing. Cell 89: 9-12, 1997.
8. Katayose, D., S. Isoyama, H. Fujita, and S. Shibahara. Separate regulation of heme oxygenase and heat shock protein 70 mRNA expression in the rat heart by hemodynamic stress. Biochem. Biophys. Res. Commun. 191: 587-594, 1993.
9. Kourembanas, S., R. L. Hannan, and D. V. Faller. Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells. J. Clin. Invest. 86: 670-674, 1990.
10. Kourembanas, S., P.A. Marsden, L. P. McQuillan, and D. V. Faller. Hypoxia induces endothelin gene expression and secretion in cultured human endothelium. J. Clin. Invest. 88: 1054-1057, 1991.
11. Kourembanas, S., L. P. McQuillan, G. K. Leung, and D. V. Faller. Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. J. Clin. Invest. 92: 99-104, 1993.
12. Kozlowski, R. Z. Ion channels, oxygen sensation and signal transduction in pulmonary arterial smooth muscle. Cardiovasc. Res. 30: 318-325, 1995.
13. Leach, R. M., and D. F. Treacher. Clinical aspects of hypoxic pulmonary vasoconstriction. Exp. Physiol. 80: 865-875, 1995.
14. Lee, P. J., J. Alam, G. W. Wiegand, and A. M. K. Choi. Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc. Natl. Acad. Sci. USA 93: 10393-10398, 1996.
15. Lee, P. J., B.-H. Jiang, B. Y. Chin, N. V. Iyer, J. Alam, G. L. Semenza, and A. M. K. Choi. Hypoxia inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J. Biol. Chem. 272: 5375-5381, 1997.
16. Lloyd, T. C. Effect of alveolar hypoxia on pulmonary vascular resistance. J. Appl. Physiol. 19: 1086-1094, 1964.
17. Maines, M. D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2: 2557-2568, 1988.
18. McCoubrey, W. K., Jr., T. J. Haung, and M. D. Maines. Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur. J. Biochem. 247: 725-732, 1997.
19. McQuillan, L. P., G. K. Leung, P. A. Marsden, S. K. Kostyk, and S. Kourembanas. Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1921-H1927, 1994.
20. Meyrick, B. R., and L. Reid. Pulmonary hypertension. Anatomic and physiologic correlates. Clin. Chest Med. 4: 199-217, 1983.
21. Millhorn, D. E., R. Raymond, L. Conforti, W. Zhu, D. Beitner-Johnson, T. Filisko, M. B. Genter, S. Kobayashi, and M. Peng. Regulation of gene expression for tyrosine hydroxylase in oxygen sensitive cells by hypoxia. Kidney Int. 51: 527-535, 1997.
22. Morita, T., and S. Kourembanas. Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide. J. Clin. Invest. 96: 2676-2682, 1995.
23. Morita, T., M. A. Perrella, M.-E. Lee, and S. Kourembanas. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc. Natl. Acad. Sci. USA 92: 1475-1479, 1995.
24. Motterlini, R., R. Foresti, M. Intaglietta, and R. M. Winslow. NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H107-H114, 1996.
25. Nath, D. A., G. Balla, G. M. Vercelotti, J. Balla, H. S. Jacob, M. D. Levitt, and M. E. Rosenberg. Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. J. Clin. Invest. 90: 267-270, 1992.
26. Otterbein, L., S. L. Sylvester, and A. M. K. Choi. Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. Am. J. Respir. Cell Mol. Biol. 13: 595-601, 1995.
27. Palmer, L. A., G. L. Semenza, M. H. Stoler, and R. A. Johns. Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L212-L219, 1998.
28. Shibahara, S., R. Muller, H. Taguchi, and T. Yoshida. Cloning and expression of cDNA for rat heme oxygenase. Proc. Natl. Acad. Sci. USA 82: 7865-7869, 1985.
29. Shweiki, D., A. Itin, D. Soffer, and E. Keshet. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845, 1992.
30. + current in rat pulmonary artery muscle cells. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H365-H370, 1994.
31. Vogt, B. A., T. P. Shanley, A. Croatt, J. Alam, K. J. Johnson, and K. A. Nath. Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury. J. Clin. Invest. 98: 2139-2145, 1996.
32. Von Euler, U., and G. Liljestrand. Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol. Scand. 12: 301-320, 1946.
33. Weir, K. E., and S. L. Archer. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J. 9: 183-189, 1995.
34. Willis, D., A. R. Moore, R. Frederick, and D. A. Willoughby. Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat. Med. 2: 87-90, 1996.
35. Yamaguchi, T., M. Terakado, F. Horio, K. Aoki, M. Tanaka, and H. Nakajima. Role of bilirubin as an antioxidant in an ischemia-reperfusion of rat liver and induction of heme oxygenase. Biochem. Biophys. Res. Commun. 223: 129-135, 1996.
36. Yu, A. Y., M. G. Frid, L. A. Shimoda, C. M. Wiener, K. Stenmark, and G. L. Semenza. Temporal, spatial, and oxygenregulated expression of hypoxia-inducible factor-1 in the lung. Am. J. Physiol. 275 (Lung Cell. Mol. Physiol. 19): L818-L826, 1998.
37. Yuan, X.-J., M. L. Tod, L. J. Rubin, and M. P. Blaustein. Hypoxic and metabolic regulation of voltage-gated K+ channels in rat pulmonary artery smooth muscle cells. Exp. Physiol. 80: 803-813, 1995.
38. Zackary, R., S. P. Gaine, J. L. Dinerman, M. Ruat, N. A. Flavahan, and S. H. Snyder. Heme oxygenase-2: endothelial and neuronal localization and role in endothelium-dependent relaxation. Proc. Natl. Acad. Sci. USA 93: 795-798, 1996.