-
1
-
-
0027057672
-
International SMA consortium meeting. (26–28 June 1992, Bonn, Germany)
-
1. TL Munsat KE Davies 1992 International SMA consortium meeting. (26–28 June 1992, Bonn, Germany) Neuromuscul Disord 2 5–6 423 428 1300191 1:STN:280:DyaK3s3jslOlsg%3D%3D 10.1016/S0960-8966(06)80015-5 Munsat TL, Davies KE (1992) International SMA consortium meeting. (26–28 June 1992, Bonn, Germany). Neuromuscul Disord 2(5–6):423–428
-
(1992)
Neuromuscul Disord
, vol.2
, Issue.5–6
, pp. 423-428
-
-
Munsat, TL1
Davies, KE2
-
2
-
-
26944503463
-
134th ENMC International workshop: outcome measures and treatment of spinal muscular atrophy, 11–13 february, 2005 Naarden, The Netherlands
-
2. E Bertini 2005 134th ENMC International workshop: outcome measures and treatment of spinal muscular atrophy, 11–13 february, 2005 Naarden, The Netherlands Neuromuscul Disord 15 11 802 816 16202598 1:STN:280:DC%2BD2Mrms1OksA%3D%3D 10.1016/j.nmd.2005.07.005 Bertini E et al (2005) 134th ENMC International workshop: outcome measures and treatment of spinal muscular atrophy, 11–13 february, 2005 Naarden, The Netherlands. Neuromuscul Disord 15(11):802–816
-
(2005)
Neuromuscul Disord
, vol.15
, Issue.11
, pp. 802-816
-
-
Bertini, E1
-
3
-
-
10244245060
-
Function changes in spinal muscular atrophy II and III. The DCN/SMA Group
-
3. BS Russman 1996 Function changes in spinal muscular atrophy II and III. The DCN/SMA Group Neurology 47 4 973 976 8857729 1:STN:280:DyaK2s%2FhtVKqtA%3D%3D 10.1212/WNL.47.4.973 Russman BS et al (1996) Function changes in spinal muscular atrophy II and III. The DCN/SMA Group. Neurology 47(4):973–976
-
(1996)
Neurology
, vol.47
, Issue.4
, pp. 973-976
-
-
Russman, BS1
-
4
-
-
0034007548
-
An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA)
-
4. B Wirth 2000 An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA) Hum Mutat 15 3 228 237 10679938 1:CAS:528:DC%2BD3cXitVGjtr0%3D 10.1002/(SICI)1098-1004(200003)15:3<228::AID-HUMU3>3.0.CO;2-9 Wirth B (2000) An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA). Hum Mutat 15(3):228–237
-
(2000)
Hum Mutat
, vol.15
, Issue.3
, pp. 228-237
-
-
Wirth, B1
-
5
-
-
0031442184
-
Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy
-
5. H Iwahashi 1997 Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy Nature 390 6658 413 417 9389483 1:CAS:528:DyaK2sXns12rtb0%3D 10.1038/37144 Iwahashi H et al (1997) Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy. Nature 390(6658):413–417
-
(1997)
Nature
, vol.390
, Issue.6658
, pp. 413-417
-
-
Iwahashi, H1
-
6
-
-
0037169562
-
A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy
-
6. PJ Young 2002 A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy J Biol Chem 277 4 2852 2859 11704667 1:CAS:528:DC%2BD38XhtVSgt70%3D 10.1074/jbc.M108769200 Young PJ et al (2002) A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy. J Biol Chem 277(4):2852–2859
-
(2002)
J Biol Chem
, vol.277
, Issue.4
, pp. 2852-2859
-
-
Young, PJ1
-
7
-
-
0035074529
-
Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein
-
7. L Gangwani 2001 Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein Nat Cell Biol 3 4 376 383 11283611 1:CAS:528:DC%2BD3MXivVygtr4%3D 10.1038/35070059 Gangwani L et al (2001) Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein. Nat Cell Biol 3(4):376–383
-
(2001)
Nat Cell Biol
, vol.3
, Issue.4
, pp. 376-383
-
-
Gangwani, L1
-
8
-
-
0346033442
-
Downregulation of Bcl-2 proteins in type I spinal muscular atrophy motor neurons during fetal development
-
8. C Soler-Botija 2003 Downregulation of Bcl-2 proteins in type I spinal muscular atrophy motor neurons during fetal development J Neuropathol Exp Neurol 62 4 420 426 12722834 1:CAS:528:DC%2BD3sXjt1yrtrw%3D Soler-Botija C et al (2003) Downregulation of Bcl-2 proteins in type I spinal muscular atrophy motor neurons during fetal development. J Neuropathol Exp Neurol 62(4):420–426
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, Issue.4
, pp. 420-426
-
-
Soler-Botija, C1
-
9
-
-
85121086560
-
-
9. Anderton RS et al (2012) Co-regulation of survival of motor neuron and Bcl-xL expression: Implications for neuroprotection in spinal muscular atrophy. Neuroscience 220:228–236
-
-
-
-
10
-
-
0028797783
-
Identification and characterization of a spinal muscular atrophy-determining gene
-
10. S Lefebvre 1995 Identification and characterization of a spinal muscular atrophy-determining gene Cell 80 1 155 165 7813012 1:CAS:528:DyaK2MXjtFegu74%3D 10.1016/0092-8674(95)90460-3 Lefebvre S et al (1995) Identification and characterization of a spinal muscular atrophy-determining gene. Cell 80(1):155–165
-
(1995)
Cell
, vol.80
, Issue.1
, pp. 155-165
-
-
Lefebvre, S1
-
11
-
-
0035073894
-
SMN gene duplication and the emergence of the SMN2 gene occurred in distinct hominids: SMN2 is unique to Homo sapiens
-
11. CF Rochette N Gilbert LR Simard 2001 SMN gene duplication and the emergence of the SMN2 gene occurred in distinct hominids: SMN2 is unique to Homo sapiens Hum Genet 108 3 255 266 11354640 1:CAS:528:DC%2BD3MXjvFynsr0%3D 10.1007/s004390100473 Rochette CF, Gilbert N, Simard LR (2001) SMN gene duplication and the emergence of the SMN2 gene occurred in distinct hominids: SMN2 is unique to Homo sapiens. Hum Genet 108(3):255–266
-
(2001)
Hum Genet
, vol.108
, Issue.3
, pp. 255-266
-
-
Rochette, CF1
Gilbert, N2
Simard, LR3
-
12
-
-
4644278816
-
Survival motor neuron SMN1 and SMN2 gene promoters: identical sequences and differential expression in neurons and non-neuronal cells
-
12. B Boda 2004 Survival motor neuron SMN1 and SMN2 gene promoters: identical sequences and differential expression in neurons and non-neuronal cells Eur J Hum Genet 12 9 729 737 15162126 1:CAS:528:DC%2BD2cXmvVarsbg%3D 10.1038/sj.ejhg.5201217 Boda B et al (2004) Survival motor neuron SMN1 and SMN2 gene promoters: identical sequences and differential expression in neurons and non-neuronal cells. Eur J Hum Genet 12(9):729–737
-
(2004)
Eur J Hum Genet
, vol.12
, Issue.9
, pp. 729-737
-
-
Boda, B1
-
13
-
-
0033033434
-
A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy
-
13. CL Lorson 1999 A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy Proc Natl Acad Sci USA 96 11 6307 6311 10339583 1:CAS:528:DyaK1MXksFKktr4%3D 10.1073/pnas.96.11.6307 Lorson CL et al (1999) A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy. Proc Natl Acad Sci USA 96(11):6307–6311
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.11
, pp. 6307-6311
-
-
Lorson, CL1
-
14
-
-
0036544654
-
Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1
-
14. L Cartegni AR Krainer 2002 Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1 Nat Genet 30 4 377 384 11925564 1:CAS:528:DC%2BD38Xisl2lsLo%3D 10.1038/ng854 Cartegni L, Krainer AR (2002) Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1. Nat Genet 30(4):377–384
-
(2002)
Nat Genet
, vol.30
, Issue.4
, pp. 377-384
-
-
Cartegni, L1
Krainer, AR2
-
15
-
-
0041665176
-
A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy
-
15. T Kashima JL Manley 2003 A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy Nat Genet 34 4 460 463 12833158 1:CAS:528:DC%2BD3sXmt1Sku7Y%3D 10.1038/ng1207 Kashima T, Manley JL (2003) A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy. Nat Genet 34(4):460–463
-
(2003)
Nat Genet
, vol.34
, Issue.4
, pp. 460-463
-
-
Kashima, T1
Manley, JL2
-
16
-
-
0035976998
-
Characterization of functional domains of the SMN protein in vivo
-
16. J Wang G Dreyfuss 2001 Characterization of functional domains of the SMN protein in vivo J Biol Chem 276 48 45387 45393 11572858 1:CAS:528:DC%2BD3MXovFentrc%3D 10.1074/jbc.M105059200 Wang J, Dreyfuss G (2001) Characterization of functional domains of the SMN protein in vivo. J Biol Chem 276(48):45387–45393
-
(2001)
J Biol Chem
, vol.276
, Issue.48
, pp. 45387-45393
-
-
Wang, J1
Dreyfuss, G2
-
17
-
-
0034701295
-
Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy
-
17. T Frugier 2000 Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy Hum Mol Genet 9 5 849 858 10749994 1:CAS:528:DC%2BD3cXitlaisLg%3D 10.1093/hmg/9.5.849 Frugier T et al (2000) Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy. Hum Mol Genet 9(5):849–858
-
(2000)
Hum Mol Genet
, vol.9
, Issue.5
, pp. 849-858
-
-
Frugier, T1
-
18
-
-
0033613150
-
SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins
-
18. L Pellizzoni B Charroux G Dreyfuss 1999 SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins Proc Natl Acad Sci USA 96 20 11167 11172 10500148 1:CAS:528:DyaK1MXmvVCnu7g%3D 10.1073/pnas.96.20.11167 Pellizzoni L, Charroux B, Dreyfuss G (1999) SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins. Proc Natl Acad Sci USA 96(20):11167–11172
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.20
, pp. 11167-11172
-
-
Pellizzoni, L1
Charroux, B2
Dreyfuss, G3
-
19
-
-
61749099937
-
Regulation of SMN protein stability
-
19. BG Burnett 2009 Regulation of SMN protein stability Mol Cell Biol 29 5 1107 1115 19103745 1:CAS:528:DC%2BD1MXitlymurk%3D 10.1128/MCB.01262-08 Burnett BG et al (2009) Regulation of SMN protein stability. Mol Cell Biol 29(5):1107–1115
-
(2009)
Mol Cell Biol
, vol.29
, Issue.5
, pp. 1107-1115
-
-
Burnett, BG1
-
20
-
-
0032457032
-
Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulated
-
20. V Bella La 1998 Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulated Eur J Neurosci 10 9 2913 2923 9758161 10.1111/j.1460-9568.1998.00298.x La Bella V et al (1998) Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulated. Eur J Neurosci 10(9):2913–2923
-
(1998)
Eur J Neurosci
, vol.10
, Issue.9
, pp. 2913-2923
-
-
Bella, V1
-
21
-
-
0029954338
-
A novel nuclear structure containing the survival of motor neurons protein
-
21. Q Liu G Dreyfuss 1996 A novel nuclear structure containing the survival of motor neurons protein EMBO J 15 14 3555 3565 8670859 1:CAS:528:DyaK28Xksl2msbg%3D Liu Q, Dreyfuss G (1996) A novel nuclear structure containing the survival of motor neurons protein. EMBO J 15(14):3555–3565
-
(1996)
EMBO J
, vol.15
, Issue.14
, pp. 3555-3565
-
-
Liu, Q1
Dreyfuss, G2
-
22
-
-
0033571601
-
The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body
-
22. T Carvalho 1999 The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body J Cell Biol 147 4 715 728 10562276 1:CAS:528:DyaK1MXnsFSqtL8%3D 10.1083/jcb.147.4.715 Carvalho T et al (1999) The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body. J Cell Biol 147(4):715–728
-
(1999)
J Cell Biol
, vol.147
, Issue.4
, pp. 715-728
-
-
Carvalho, T1
-
23
-
-
0035325266
-
Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN
-
23. PJ Young 2001 Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN Exp Cell Res 265 2 252 261 11302690 1:CAS:528:DC%2BD3MXis1ert7o%3D 10.1006/excr.2001.5186 Young PJ et al (2001) Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN. Exp Cell Res 265(2):252–261
-
(2001)
Exp Cell Res
, vol.265
, Issue.2
, pp. 252-261
-
-
Young, PJ1
-
24
-
-
0035887042
-
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
-
24. MD Hebert 2001 Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein Genes Dev 15 20 2720 2729 11641277 1:CAS:528:DC%2BD3MXnvVWksb0%3D 10.1101/gad.908401 Hebert MD et al (2001) Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein. Genes Dev 15(20):2720–2729
-
(2001)
Genes Dev
, vol.15
, Issue.20
, pp. 2720-2729
-
-
Hebert, MD1
-
25
-
-
2142754136
-
The SMN complex
-
25. AK Gubitz W Feng G Dreyfuss 2004 The SMN complex Exp Cell Res 296 1 51 56 15120993 1:CAS:528:DC%2BD2cXjs1Cju78%3D 10.1016/j.yexcr.2004.03.022 Gubitz AK, Feng W, Dreyfuss G (2004) The SMN complex. Exp Cell Res 296(1):51–56
-
(2004)
Exp Cell Res
, vol.296
, Issue.1
, pp. 51-56
-
-
Gubitz, AK1
Feng, W2
Dreyfuss, G3
-
26
-
-
0032568567
-
Heterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissues
-
26. JW Francis 1998 Heterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissues Proc Natl Acad Sci USA 95 11 6492 6497 9600994 1:CAS:528:DyaK1cXjtlKgur8%3D 10.1073/pnas.95.11.6492 Francis JW et al (1998) Heterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissues. Proc Natl Acad Sci USA 95(11):6492–6497
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 6492-6497
-
-
Francis, JW1
-
27
-
-
0034096078
-
Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord
-
27. S Pagliardini 2000 Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord Hum Mol Genet 9 1 47 56 10587577 1:CAS:528:DC%2BD3cXmt1ertw%3D%3D 10.1093/hmg/9.1.47 Pagliardini S et al (2000) Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord. Hum Mol Genet 9(1):47–56
-
(2000)
Hum Mol Genet
, vol.9
, Issue.1
, pp. 47-56
-
-
Pagliardini, S1
-
28
-
-
0033519596
-
Localization of survival motor neuron protein in human apoptotic-like and regenerating muscle fibers, and neuromuscular junctions
-
28. A Broccolini WK Engel V Askanas 1999 Localization of survival motor neuron protein in human apoptotic-like and regenerating muscle fibers, and neuromuscular junctions Neuroreport 10 8 1637 1641 10501549 1:CAS:528:DyaK1MXksFaltLk%3D 10.1097/00001756-199906030-00003 Broccolini A, Engel WK, Askanas V (1999) Localization of survival motor neuron protein in human apoptotic-like and regenerating muscle fibers, and neuromuscular junctions. Neuroreport 10(8):1637–1641
-
(1999)
Neuroreport
, vol.10
, Issue.8
, pp. 1637-1641
-
-
Broccolini, A1
Engel, WK2
Askanas, V3
-
29
-
-
0030776040
-
Expression of the SMN gene, the spinal muscular atrophy determining gene, in the mammalian central nervous system
-
29. G Battaglia 1997 Expression of the SMN gene, the spinal muscular atrophy determining gene, in the mammalian central nervous system Hum Mol Genet 6 11 1961 1971 9302277 1:CAS:528:DyaK2sXmslKitL4%3D 10.1093/hmg/6.11.1961 Battaglia G et al (1997) Expression of the SMN gene, the spinal muscular atrophy determining gene, in the mammalian central nervous system. Hum Mol Genet 6(11):1961–1971
-
(1997)
Hum Mol Genet
, vol.6
, Issue.11
, pp. 1961-1971
-
-
Battaglia, G1
-
30
-
-
84863011418
-
A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy
-
30. M Ruggiu 2012 A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy Mol Cell Biol 32 1 126 138 22037760 1:CAS:528:DC%2BC38Xjt12ms7s%3D 10.1128/MCB.06077-11 Ruggiu M et al (2012) A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy. Mol Cell Biol 32(1):126–138
-
(2012)
Mol Cell Biol
, vol.32
, Issue.1
, pp. 126-138
-
-
Ruggiu, M1
-
31
-
-
49049091331
-
Pathogenesis of proximal autosomal recessive spinal muscular atrophy
-
31. G Simic 2008 Pathogenesis of proximal autosomal recessive spinal muscular atrophy Acta Neuropathol 116 3 223 234 18629520 1:CAS:528:DC%2BD1cXpsVCqurY%3D 10.1007/s00401-008-0411-1 Simic G (2008) Pathogenesis of proximal autosomal recessive spinal muscular atrophy. Acta Neuropathol 116(3):223–234
-
(2008)
Acta Neuropathol
, vol.116
, Issue.3
, pp. 223-234
-
-
Simic, G1
-
32
-
-
0030931727
-
The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins
-
32. Q Liu 1997 The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins Cell 90 6 1013 1021 9323129 1:CAS:528:DyaK2sXmtlOgur0%3D 10.1016/S0092-8674(00)80367-0 Liu Q et al (1997) The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell 90(6):1013–1021
-
(1997)
Cell
, vol.90
, Issue.6
, pp. 1013-1021
-
-
Liu, Q1
-
33
-
-
0033552589
-
Gemin3: a novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems
-
33. B Charroux 1999 Gemin3: a novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems J Cell Biol 147 6 1181 1194 10601333 1:CAS:528:DyaK1MXotVGqtbg%3D 10.1083/jcb.147.6.1181 Charroux B et al (1999) Gemin3: a novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. J Cell Biol 147(6):1181–1194
-
(1999)
J Cell Biol
, vol.147
, Issue.6
, pp. 1181-1194
-
-
Charroux, B1
-
34
-
-
0034688999
-
Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli
-
34. B Charroux 2000 Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli J Cell Biol 148 6 1177 1186 10725331 1:CAS:528:DC%2BD3cXitVaqtrY%3D 10.1083/jcb.148.6.1177 Charroux B et al (2000) Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. J Cell Biol 148(6):1177–1186
-
(2000)
J Cell Biol
, vol.148
, Issue.6
, pp. 1177-1186
-
-
Charroux, B1
-
35
-
-
0037200002
-
Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex
-
35. J Baccon 2002 Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex J Biol Chem 277 35 31957 31962 12065586 1:CAS:528:DC%2BD38XmslOqurk%3D 10.1074/jbc.M203478200 Baccon J et al (2002) Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. J Biol Chem 277(35):31957–31962
-
(2002)
J Biol Chem
, vol.277
, Issue.35
, pp. 31957-31962
-
-
Baccon, J1
-
36
-
-
0037085390
-
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins
-
36. AK Gubitz 2002 Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins J Biol Chem 277 7 5631 5636 11714716 1:CAS:528:DC%2BD38XhsFCjtLY%3D 10.1074/jbc.M109448200 Gubitz AK et al (2002) Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. J Biol Chem 277(7):5631–5636
-
(2002)
J Biol Chem
, vol.277
, Issue.7
, pp. 5631-5636
-
-
Gubitz, AK1
-
37
-
-
2242443509
-
Essential role for the SMN complex in the specificity of snRNP assembly
-
37. L Pellizzoni J Yong G Dreyfuss 2002 Essential role for the SMN complex in the specificity of snRNP assembly Science 298 5599 1775 1779 12459587 1:CAS:528:DC%2BD38XovFKms7w%3D 10.1126/science.1074962 Pellizzoni L, Yong J, Dreyfuss G (2002) Essential role for the SMN complex in the specificity of snRNP assembly. Science 298(5599):1775–1779
-
(2002)
Science
, vol.298
, Issue.5599
, pp. 1775-1779
-
-
Pellizzoni, L1
Yong, J2
Dreyfuss, G3
-
38
-
-
33646377172
-
Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly
-
38. C Carissimi 2006 Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly J Biol Chem 281 12 8126 8134 16434402 1:CAS:528:DC%2BD28Xitl2rsLw%3D 10.1074/jbc.M512243200 Carissimi C et al (2006) Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. J Biol Chem 281(12):8126–8134
-
(2006)
J Biol Chem
, vol.281
, Issue.12
, pp. 8126-8134
-
-
Carissimi, C1
-
39
-
-
0032862988
-
Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner
-
39. VA Raker 1999 Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner Mol Cell Biol 19 10 6554 6565 10490595 1:CAS:528:DyaK1MXmtlamtbk%3D Raker VA et al (1999) Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner. Mol Cell Biol 19(10):6554–6565
-
(1999)
Mol Cell Biol
, vol.19
, Issue.10
, pp. 6554-6565
-
-
Raker, VA1
-
40
-
-
34047148903
-
Chaperoning ribonucleoprotein biogenesis in health and disease
-
40. L Pellizzoni 2007 Chaperoning ribonucleoprotein biogenesis in health and disease EMBO Rep 8 4 340 345 17401408 1:CAS:528:DC%2BD2sXjs1yqtbo%3D 10.1038/sj.embor.7400941 Pellizzoni L (2007) Chaperoning ribonucleoprotein biogenesis in health and disease. EMBO Rep 8(4):340–345
-
(2007)
EMBO Rep
, vol.8
, Issue.4
, pp. 340-345
-
-
Pellizzoni, L1
-
41
-
-
34548152119
-
Molecular functions of the SMN complex
-
41. SJ Kolb DJ Battle G Dreyfuss 2007 Molecular functions of the SMN complex J Child Neurol 22 8 990 994 17761654 10.1177/0883073807305666 Kolb SJ, Battle DJ, Dreyfuss G (2007) Molecular functions of the SMN complex. J Child Neurol 22(8):990–994
-
(2007)
J Child Neurol
, vol.22
, Issue.8
, pp. 990-994
-
-
Kolb, SJ1
Battle, DJ2
Dreyfuss, G3
-
42
-
-
0035370526
-
Spliceosomal UsnRNP biogenesis, structure and function
-
42. CL Will R Luhrmann 2001 Spliceosomal UsnRNP biogenesis, structure and function Curr Opin Cell Biol 13 3 290 301 11343899 1:CAS:528:DC%2BD3MXktVaju78%3D 10.1016/S0955-0674(00)00211-8 Will CL, Luhrmann R (2001) Spliceosomal UsnRNP biogenesis, structure and function. Curr Opin Cell Biol 13(3):290–301
-
(2001)
Curr Opin Cell Biol
, vol.13
, Issue.3
, pp. 290-301
-
-
Will, CL1
Luhrmann, R2
-
43
-
-
73949149584
-
RNA processing defects associated with diseases of the motor neuron
-
43. SJ Kolb S Sutton DR Schoenberg 2010 RNA processing defects associated with diseases of the motor neuron Muscle Nerve 41 1 5 17 19697368 1:CAS:528:DC%2BC3cXht1Ogtbg%3D 10.1002/mus.21428 Kolb SJ, Sutton S, Schoenberg DR (2010) RNA processing defects associated with diseases of the motor neuron. Muscle Nerve 41(1):5–17
-
(2010)
Muscle Nerve
, vol.41
, Issue.1
, pp. 5-17
-
-
Kolb, SJ1
Sutton, S2
Schoenberg, DR3
-
44
-
-
67651083390
-
Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
-
44. AH Burghes CE Beattie 2009 Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick? Nat Rev Neurosci 10 8 597 609 19584893 1:CAS:528:DC%2BD1MXotlSnsrc%3D 10.1038/nrn2670 Burghes AH, Beattie CE (2009) Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick? Nat Rev Neurosci 10(8):597–609
-
(2009)
Nat Rev Neurosci
, vol.10
, Issue.8
, pp. 597-609
-
-
Burghes, AH1
Beattie, CE2
-
45
-
-
84867555865
-
An SMN-dependent U12 splicing event essential for motor circuit function
-
45. F Lotti 2012 An SMN-dependent U12 splicing event essential for motor circuit function Cell 151 2 440 454 23063131 1:CAS:528:DC%2BC38XhsV2qu7vK 10.1016/j.cell.2012.09.012 Lotti F et al (2012) An SMN-dependent U12 splicing event essential for motor circuit function. Cell 151(2):440–454
-
(2012)
Cell
, vol.151
, Issue.2
, pp. 440-454
-
-
Lotti, F1
-
46
-
-
0042202619
-
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization
-
46. HL Zhang 2003 Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization J Neurosci 23 16 6627 6637 12878704 1:CAS:528:DC%2BD3sXlvF2mt7s%3D Zhang HL et al (2003) Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization. J Neurosci 23(16):6627–6637
-
(2003)
J Neurosci
, vol.23
, Issue.16
, pp. 6627-6637
-
-
Zhang, HL1
-
47
-
-
0042887389
-
Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding
-
47. ML McWhorter 2003 Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding J Cell Biol 162 5 919 931 12952942 1:CAS:528:DC%2BD3sXntFeqsbo%3D 10.1083/jcb.200303168 McWhorter ML et al (2003) Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding. J Cell Biol 162(5):919–931
-
(2003)
J Cell Biol
, vol.162
, Issue.5
, pp. 919-931
-
-
McWhorter, ML1
-
48
-
-
33751100104
-
Survival motor neuron function in motor axons is independent of functions required for small nuclear ribonucleoprotein biogenesis
-
48. TL Carrel 2006 Survival motor neuron function in motor axons is independent of functions required for small nuclear ribonucleoprotein biogenesis J Neurosci 26 43 11014 11022 17065443 1:CAS:528:DC%2BD28XhtFymsLjL 10.1523/JNEUROSCI.1637-06.2006 Carrel TL et al (2006) Survival motor neuron function in motor axons is independent of functions required for small nuclear ribonucleoprotein biogenesis. J Neurosci 26(43):11014–11022
-
(2006)
J Neurosci
, vol.26
, Issue.43
, pp. 11014-11022
-
-
Carrel, TL1
-
49
-
-
79952390939
-
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons
-
49. C Fallini 2011 The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons J Neurosci 31 10 3914 3925 21389246 1:CAS:528:DC%2BC3MXjslGqtbY%3D 10.1523/JNEUROSCI.3631-10.2011 Fallini C et al (2011) The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci 31(10):3914–3925
-
(2011)
J Neurosci
, vol.31
, Issue.10
, pp. 3914-3925
-
-
Fallini, C1
-
50
-
-
0015383455
-
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
-
50. JF Kerr AH Wyllie AR Currie 1972 Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer 26 4 239 257 4561027 1:STN:280:DyaE3s%2FgsFSksw%3D%3D 10.1038/bjc.1972.33 Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26(4):239–257
-
(1972)
Br J Cancer
, vol.26
, Issue.4
, pp. 239-257
-
-
Kerr, JF1
Wyllie, AH2
Currie, AR3
-
51
-
-
34250308322
-
Apoptosis: a review of programmed cell death
-
51. S Elmore 2007 Apoptosis: a review of programmed cell death Toxicol Pathol 35 4 495 516 17562483 1:CAS:528:DC%2BD2sXmtlWmtb4%3D 10.1080/01926230701320337 Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35(4):495–516
-
(2007)
Toxicol Pathol
, vol.35
, Issue.4
, pp. 495-516
-
-
Elmore, S1
-
52
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
52. MP Mattson 2000 Apoptosis in neurodegenerative disorders Nat Rev Mol Cell Biol 1 2 120 129 11253364 1:CAS:528:DC%2BD3MXivVGjtbk%3D 10.1038/35040009 Mattson MP (2000) Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 1(2):120–129
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, Issue.2
, pp. 120-129
-
-
Mattson, MP1
-
53
-
-
13544249779
-
Defining the role of the Bcl-2 family of proteins in the nervous system
-
53. T Lindsten WX Zong CB Thompson 2005 Defining the role of the Bcl-2 family of proteins in the nervous system Neuroscientist 11 1 10 15 15632274 1:CAS:528:DC%2BD2MXht1ylsrk%3D 10.1177/1073858404269267 Lindsten T, Zong WX, Thompson CB (2005) Defining the role of the Bcl-2 family of proteins in the nervous system. Neuroscientist 11(1):10–15
-
(2005)
Neuroscientist
, vol.11
, Issue.1
, pp. 10-15
-
-
Lindsten, T1
Zong, WX2
Thompson, CB3
-
54
-
-
0026058318
-
Cell death during development of the nervous system
-
54. RW Oppenheim 1991 Cell death during development of the nervous system Annu Rev Neurosci 14 453 501 2031577 1:STN:280:DyaK3M3jsVSnsw%3D%3D 10.1146/annurev.ne.14.030191.002321 Oppenheim RW (1991) Cell death during development of the nervous system. Annu Rev Neurosci 14:453–501
-
(1991)
Annu Rev Neurosci
, vol.14
, pp. 453-501
-
-
Oppenheim, RW1
-
55
-
-
0031826405
-
The role of apoptosis in neurodegenerative diseases
-
55. P Desjardins S Ledoux 1998 The role of apoptosis in neurodegenerative diseases Metab Brain Dis 13 2 79 96 9699918 1:CAS:528:DyaK1cXltlChsLg%3D 10.1023/A:1020605112755 Desjardins P, Ledoux S (1998) The role of apoptosis in neurodegenerative diseases. Metab Brain Dis 13(2):79–96
-
(1998)
Metab Brain Dis
, vol.13
, Issue.2
, pp. 79-96
-
-
Desjardins, P1
Ledoux, S2
-
56
-
-
0032896327
-
Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism
-
56. LJ Martin 1999 Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism J Neuropathol Exp Neurol 58 5 459 471 10331434 1:STN:280:DyaK1M3mtVaktQ%3D%3D 10.1097/00005072-199905000-00005 Martin LJ (1999) Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism. J Neuropathol Exp Neurol 58(5):459–471
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, Issue.5
, pp. 459-471
-
-
Martin, LJ1
-
57
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
57. DW Cleveland JD Rothstein 2001 From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS Nat Rev Neurosci 2 11 806 819 11715057 1:CAS:528:DC%2BD38Xmt1WitLs%3D 10.1038/35097565 Cleveland DW, Rothstein JD (2001) From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2(11):806–819
-
(2001)
Nat Rev Neurosci
, vol.2
, Issue.11
, pp. 806-819
-
-
Cleveland, DW1
Rothstein, JD2
-
58
-
-
0034061620
-
Ultrastructural analysis and TUNEL demonstrate motor neuron apoptosis in Werdnig–Hoffmann disease
-
58. G Simic 2000 Ultrastructural analysis and TUNEL demonstrate motor neuron apoptosis in Werdnig–Hoffmann disease J Neuropathol Exp Neurol 59 5 398 407 10888370 1:STN:280:DC%2BD3czksVaqtg%3D%3D Simic G et al (2000) Ultrastructural analysis and TUNEL demonstrate motor neuron apoptosis in Werdnig–Hoffmann disease. J Neuropathol Exp Neurol 59(5):398–407
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, Issue.5
, pp. 398-407
-
-
Simic, G1
-
59
-
-
0036310343
-
Neuronal death is enhanced and begins during foetal development in type I spinal muscular atrophy spinal cord
-
59. C Soler-Botija 2002 Neuronal death is enhanced and begins during foetal development in type I spinal muscular atrophy spinal cord Brain 125 Pt 7 1624 1634 12077011 10.1093/brain/awf155 Soler-Botija C et al (2002) Neuronal death is enhanced and begins during foetal development in type I spinal muscular atrophy spinal cord. Brain 125(Pt 7):1624–1634
-
(2002)
Brain
, vol.125
, Issue.Pt 7
, pp. 1624-1634
-
-
Soler-Botija, C1
-
60
-
-
33646881769
-
Abolishing Bax-dependent apoptosis shows beneficial effects on spinal muscular atrophy model mice
-
60. MS Tsai 2006 Abolishing Bax-dependent apoptosis shows beneficial effects on spinal muscular atrophy model mice Mol Ther 13 6 1149 1155 16564230 1:CAS:528:DC%2BD28XltFCltrs%3D 10.1016/j.ymthe.2006.02.008 Tsai MS et al (2006) Abolishing Bax-dependent apoptosis shows beneficial effects on spinal muscular atrophy model mice. Mol Ther 13(6):1149–1155
-
(2006)
Mol Ther
, vol.13
, Issue.6
, pp. 1149-1155
-
-
Tsai, MS1
-
61
-
-
33645162940
-
Abolishing Trp53-dependent apoptosis does not benefit spinal muscular atrophy model mice
-
61. MS Tsai 2006 Abolishing Trp53-dependent apoptosis does not benefit spinal muscular atrophy model mice Eur J Hum Genet 14 3 372 375 16391561 1:CAS:528:DC%2BD28Xhs1eqtrg%3D 10.1038/sj.ejhg.5201556 Tsai MS et al (2006) Abolishing Trp53-dependent apoptosis does not benefit spinal muscular atrophy model mice. Eur J Hum Genet 14(3):372–375
-
(2006)
Eur J Hum Genet
, vol.14
, Issue.3
, pp. 372-375
-
-
Tsai, MS1
-
62
-
-
44649087310
-
Survival motor neuron protein regulates apoptosis in an in vitro model of spinal muscular atrophy
-
62. GC Parker 2008 Survival motor neuron protein regulates apoptosis in an in vitro model of spinal muscular atrophy Neurotox Res 13 1 39 48 18367439 1:CAS:528:DC%2BD1cXntV2ns7Y%3D 10.1007/BF03033366 Parker GC et al (2008) Survival motor neuron protein regulates apoptosis in an in vitro model of spinal muscular atrophy. Neurotox Res 13(1):39–48
-
(2008)
Neurotox Res
, vol.13
, Issue.1
, pp. 39-48
-
-
Parker, GC1
-
63
-
-
0037109143
-
Involvement of survival motor neuron (SMN) protein in cell death
-
63. S Vyas 2002 Involvement of survival motor neuron (SMN) protein in cell death Hum Mol Genet 11 22 2751 2764 12374765 1:CAS:528:DC%2BD38XotVSjsbw%3D 10.1093/hmg/11.22.2751 Vyas S et al (2002) Involvement of survival motor neuron (SMN) protein in cell death. Hum Mol Genet 11(22):2751–2764
-
(2002)
Hum Mol Genet
, vol.11
, Issue.22
, pp. 2751-2764
-
-
Vyas, S1
-
64
-
-
18044361919
-
Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin-induced cell death
-
64. W Wang 2005 Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin-induced cell death Mol Genet Metab 85 1 38 45 15862279 1:CAS:528:DC%2BD2MXjs1Oju7s%3D 10.1016/j.ymgme.2004.12.015 Wang W et al (2005) Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin-induced cell death. Mol Genet Metab 85(1):38–45
-
(2005)
Mol Genet Metab
, vol.85
, Issue.1
, pp. 38-45
-
-
Wang, W1
-
65
-
-
79953718027
-
Survival of motor neuron protein over-expression prevents calpain-mediated cleavage and activation of procaspase-3 in differentiated human SH-SY5Y cells
-
65. RS Anderton 2011 Survival of motor neuron protein over-expression prevents calpain-mediated cleavage and activation of procaspase-3 in differentiated human SH-SY5Y cells Neuroscience 181 226 233 21333717 1:CAS:528:DC%2BC3MXks1Wksbg%3D 10.1016/j.neuroscience.2011.02.032 Anderton RS et al (2011) Survival of motor neuron protein over-expression prevents calpain-mediated cleavage and activation of procaspase-3 in differentiated human SH-SY5Y cells. Neuroscience 181:226–233
-
(2011)
Neuroscience
, vol.181
, pp. 226-233
-
-
Anderton, RS1
-
66
-
-
0034700180
-
Survival motor neuron protein modulates neuron-specific apoptosis
-
66. DA Kerr 2000 Survival motor neuron protein modulates neuron-specific apoptosis Proc Natl Acad Sci USA 97 24 13312 13317 11078511 1:CAS:528:DC%2BD3cXosVOjsrk%3D 10.1073/pnas.230364197 Kerr DA et al (2000) Survival motor neuron protein modulates neuron-specific apoptosis. Proc Natl Acad Sci USA 97(24):13312–13317
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.24
, pp. 13312-13317
-
-
Kerr, DA1
-
67
-
-
0030976895
-
A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro
-
67. Z Han 1997 A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro J Biol Chem 272 20 13432 13436 9148968 1:CAS:528:DyaK2sXjtlaru7o%3D 10.1074/jbc.272.20.13432 Han Z et al (1997) A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro. J Biol Chem 272(20):13432–13436
-
(1997)
J Biol Chem
, vol.272
, Issue.20
, pp. 13432-13436
-
-
Han, Z1
-
68
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
68. QL Deveraux 1998 IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases EMBO J 17 8 2215 2223 9545235 1:CAS:528:DyaK1cXivFOmsb8%3D 10.1093/emboj/17.8.2215 Deveraux QL et al (1998) IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J 17(8):2215–2223
-
(1998)
EMBO J
, vol.17
, Issue.8
, pp. 2215-2223
-
-
Deveraux, QL1
-
69
-
-
0034234532
-
The short prodomain influences caspase-3 activation in HeLa cells
-
69. T Meergans 2000 The short prodomain influences caspase-3 activation in HeLa cells Biochem J 349 Pt 1 135 140 10861221 1:CAS:528:DC%2BD3cXlt1Snsro%3D 10.1042/0264-6021:3490135 Meergans T et al (2000) The short prodomain influences caspase-3 activation in HeLa cells. Biochem J 349(Pt 1):135–140
-
(2000)
Biochem J
, vol.349
, Issue.Pt 1
, pp. 135-140
-
-
Meergans, T1
-
70
-
-
36048992832
-
Knockdown of SMN by RNA interference induces apoptosis in differentiated P19 neural stem cells
-
70. B Trulzsch 2007 Knockdown of SMN by RNA interference induces apoptosis in differentiated P19 neural stem cells Brain Res 1183 1 9 17976539 10.1016/j.brainres.2007.09.025 1:CAS:528:DC%2BD2sXhtlWksL3M Trulzsch B et al (2007) Knockdown of SMN by RNA interference induces apoptosis in differentiated P19 neural stem cells. Brain Res 1183:1–9
-
(2007)
Brain Res
, vol.1183
, pp. 1-9
-
-
Trulzsch, B1
-
71
-
-
84862518720
-
Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy
-
71. D Sareen 2012 Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy PLoS One 7 6 e39113 22723941 1:CAS:528:DC%2BC38XptlSnsLw%3D 10.1371/journal.pone.0039113 Sareen D et al (2012) Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. PLoS One 7(6):e39113
-
(2012)
PLoS One
, vol.7
, Issue.6
, pp. e39113
-
-
Sareen, D1
-
72
-
-
54449098255
-
SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain
-
72. MP Walker 2008 SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain Hum Mol Genet 17 21 3399 3410 18689355 1:CAS:528:DC%2BD1cXht1entrrL 10.1093/hmg/ddn234 Walker MP et al (2008) SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain. Hum Mol Genet 17(21):3399–3410
-
(2008)
Hum Mol Genet
, vol.17
, Issue.21
, pp. 3399-3410
-
-
Walker, MP1
-
73
-
-
78651254380
-
Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain
-
73. JL Fuentes MS Strayer AG Matera 2010 Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain PLoS One 5 12 e15769 21209906 1:CAS:528:DC%2BC3MXlsl2ltw%3D%3D 10.1371/journal.pone.0015769 Fuentes JL, Strayer MS, Matera AG (2010) Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain. PLoS One 5(12):e15769
-
(2010)
PLoS One
, vol.5
, Issue.12
, pp. e15769
-
-
Fuentes, JL1
Strayer, MS2
Matera, AG3
-
74
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
74. A Gross JM McDonnell SJ Korsmeyer 1999 BCL-2 family members and the mitochondria in apoptosis Genes Dev 13 15 1899 1911 10444588 1:CAS:528:DyaK1MXltlGktrg%3D 10.1101/gad.13.15.1899 Gross A, McDonnell JM, Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13(15):1899–1911
-
(1999)
Genes Dev
, vol.13
, Issue.15
, pp. 1899-1911
-
-
Gross, A1
McDonnell, JM2
Korsmeyer, SJ3
-
75
-
-
0242522206
-
Regulation of apoptosis by Bcl-2 family proteins
-
75. A Burlacu 2003 Regulation of apoptosis by Bcl-2 family proteins J Cell Mol Med 7 3 249 257 14594549 1:CAS:528:DC%2BD2MXltVWrtb0%3D 10.1111/j.1582-4934.2003.tb00225.x Burlacu A (2003) Regulation of apoptosis by Bcl-2 family proteins. J Cell Mol Med 7(3):249–257
-
(2003)
J Cell Mol Med
, vol.7
, Issue.3
, pp. 249-257
-
-
Burlacu, A1
-
76
-
-
0034035329
-
Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product
-
76. K Sato 2000 Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product Cell Death Differ 7 4 374 383 10773822 1:CAS:528:DC%2BD3cXjt1Kisbo%3D 10.1038/sj.cdd.4400660 Sato K et al (2000) Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product. Cell Death Differ 7(4):374–383
-
(2000)
Cell Death Differ
, vol.7
, Issue.4
, pp. 374-383
-
-
Sato, K1
-
77
-
-
0041821398
-
Protein expression changes in spinal muscular atrophy revealed with a novel antibody array technology
-
77. K Anderson 2003 Protein expression changes in spinal muscular atrophy revealed with a novel antibody array technology Brain 126 Pt 9 2052 2064 12847076 1:STN:280:DC%2BD3szpslyitQ%3D%3D 10.1093/brain/awg208 Anderson K et al (2003) Protein expression changes in spinal muscular atrophy revealed with a novel antibody array technology. Brain 126(Pt 9):2052–2064
-
(2003)
Brain
, vol.126
, Issue.Pt 9
, pp. 2052-2064
-
-
Anderson, K1
-
78
-
-
0029164446
-
The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis
-
78. S Maheswaran 1995 The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis Genes Dev 9 17 2143 2156 7657166 1:CAS:528:DyaK2MXotVOnu7s%3D 10.1101/gad.9.17.2143 Maheswaran S et al (1995) The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis. Genes Dev 9(17):2143–2156
-
(1995)
Genes Dev
, vol.9
, Issue.17
, pp. 2143-2156
-
-
Maheswaran, S1
-
79
-
-
0033565656
-
WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene
-
79. MW Mayo 1999 WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene EMBO J 18 14 3990 4003 10406804 1:CAS:528:DyaK1MXkvV2is78%3D 10.1093/emboj/18.14.3990 Mayo MW et al (1999) WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene. EMBO J 18(14):3990–4003
-
(1999)
EMBO J
, vol.18
, Issue.14
, pp. 3990-4003
-
-
Mayo, MW1
-
80
-
-
0141834020
-
Evidence for a modifying pathway in SMA discordant families: reduced SMN level decreases the amount of its interacting partners and Htra2-beta1
-
80. C Helmken 2003 Evidence for a modifying pathway in SMA discordant families: reduced SMN level decreases the amount of its interacting partners and Htra2-beta1 Hum Genet 114 1 11 21 14520560 1:CAS:528:DC%2BD3sXovFOisbY%3D 10.1007/s00439-003-1025-2 Helmken C et al (2003) Evidence for a modifying pathway in SMA discordant families: reduced SMN level decreases the amount of its interacting partners and Htra2-beta1. Hum Genet 114(1):11–21
-
(2003)
Hum Genet
, vol.114
, Issue.1
, pp. 11-21
-
-
Helmken, C1
-
81
-
-
15044365086
-
ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies
-
81. L Gangwani RA Flavell RJ Davis 2005 ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies Mol Cell Biol 25 7 2744 2756 15767679 1:CAS:528:DC%2BD2MXis12jurY%3D 10.1128/MCB.25.7.2744-2756.2005 Gangwani L, Flavell RA, Davis RJ (2005) ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies. Mol Cell Biol 25(7):2744–2756
-
(2005)
Mol Cell Biol
, vol.25
, Issue.7
, pp. 2744-2756
-
-
Gangwani, L1
Flavell, RA2
Davis, RJ3
-
82
-
-
33646598354
-
Deficiency of the zinc finger protein ZPR1 causes neurodegeneration
-
82. B Doran 2006 Deficiency of the zinc finger protein ZPR1 causes neurodegeneration Proc Natl Acad Sci USA 103 19 7471 7475 16648254 1:CAS:528:DC%2BD28XkslOrtLs%3D 10.1073/pnas.0602057103 Doran B et al (2006) Deficiency of the zinc finger protein ZPR1 causes neurodegeneration. Proc Natl Acad Sci USA 103(19):7471–7475
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.19
, pp. 7471-7475
-
-
Doran, B1
-
83
-
-
0035370483
-
Regulation and function of the p53 tumor suppressor protein
-
83. KM Ryan AC Phillips KH Vousden 2001 Regulation and function of the p53 tumor suppressor protein Curr Opin Cell Biol 13 3 332 337 11343904 1:CAS:528:DC%2BD3MXktVaju7g%3D 10.1016/S0955-0674(00)00216-7 Ryan KM, Phillips AC, Vousden KH (2001) Regulation and function of the p53 tumor suppressor protein. Curr Opin Cell Biol 13(3):332–337
-
(2001)
Curr Opin Cell Biol
, vol.13
, Issue.3
, pp. 332-337
-
-
Ryan, KM1
Phillips, AC2
Vousden, KH3
-
84
-
-
0036247821
-
p53-Mdm2—the affair that never ends
-
84. D Alarcon-Vargas Z Ronai 2002 p53-Mdm2—the affair that never ends Carcinogenesis 23 4 541 547 11960904 1:CAS:528:DC%2BD38XjvVGrt7g%3D 10.1093/carcin/23.4.541 Alarcon-Vargas D, Ronai Z (2002) p53-Mdm2—the affair that never ends. Carcinogenesis 23(4):541–547
-
(2002)
Carcinogenesis
, vol.23
, Issue.4
, pp. 541-547
-
-
Alarcon-Vargas, D1
Ronai, Z2
-
85
-
-
0034704923
-
The loss of mdm2 induces p53-mediated apoptosis
-
85. S Rozieres de 2000 The loss of mdm2 induces p53-mediated apoptosis Oncogene 19 13 1691 1697 10763826 10.1038/sj.onc.1203468 1:CAS:528:DC%2BD3cXivVartLY%3D de Rozieres S et al (2000) The loss of mdm2 induces p53-mediated apoptosis. Oncogene 19(13):1691–1697
-
(2000)
Oncogene
, vol.19
, Issue.13
, pp. 1691-1697
-
-
Rozieres, S1
-
86
-
-
0027282044
-
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
86. LH Boise 1993 bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death Cell 74 4 597 608 8358789 1:CAS:528:DyaK3sXmsVans7g%3D 10.1016/0092-8674(93)90508-N Boise LH et al (1993) bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74(4):597–608
-
(1993)
Cell
, vol.74
, Issue.4
, pp. 597-608
-
-
Boise, LH1
-
87
-
-
0028170778
-
bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
-
87. M Gonzalez-Garcia 1994 bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria Development 120 10 3033 3042 7607090 1:CAS:528:DyaK2MXhtl2mu78%3D Gonzalez-Garcia M et al (1994) bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development 120(10):3033–3042
-
(1994)
Development
, vol.120
, Issue.10
, pp. 3033-3042
-
-
Gonzalez-Garcia, M1
-
88
-
-
0030843575
-
Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
-
88. CN Kim 1997 Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis Cancer Res 57 15 3115 3120 9242435 1:CAS:528:DyaK2sXkvFKrurc%3D Kim CN et al (1997) Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res 57(15):3115–3120
-
(1997)
Cancer Res
, vol.57
, Issue.15
, pp. 3115-3120
-
-
Kim, CN1
-
89
-
-
0032515874
-
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
-
89. Y Hu 1998 Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation Proc Natl Acad Sci USA 95 8 4386 4391 9539746 1:CAS:528:DyaK1cXis1Ohu74%3D 10.1073/pnas.95.8.4386 Hu Y et al (1998) Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc Natl Acad Sci USA 95(8):4386–4391
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.8
, pp. 4386-4391
-
-
Hu, Y1
-
90
-
-
0028922885
-
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice
-
90. N Motoyama 1995 Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice Science 267 5203 1506 1510 7878471 1:CAS:528:DyaK2MXktlCltLk%3D 10.1126/science.7878471 Motoyama N et al (1995) Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267(5203):1506–1510
-
(1995)
Science
, vol.267
, Issue.5203
, pp. 1506-1510
-
-
Motoyama, N1
-
91
-
-
49349107825
-
Restoring Bcl-x(L) levels benefits a mouse model of spinal muscular atrophy
-
91. LK Tsai 2008 Restoring Bcl-x(L) levels benefits a mouse model of spinal muscular atrophy Neurobiol Dis 31 3 361 367 18590823 1:CAS:528:DC%2BD1cXhtVSisrfL 10.1016/j.nbd.2008.05.014 Tsai LK et al (2008) Restoring Bcl-x(L) levels benefits a mouse model of spinal muscular atrophy. Neurobiol Dis 31(3):361–367
-
(2008)
Neurobiol Dis
, vol.31
, Issue.3
, pp. 361-367
-
-
Tsai, LK1
-
92
-
-
33947712084
-
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x
-
92. MP Paronetto 2007 The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x J Cell Biol 176 7 929 939 17371836 1:CAS:528:DC%2BD2sXjvVSnsb4%3D 10.1083/jcb.200701005 Paronetto MP et al (2007) The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x. J Cell Biol 176(7):929–939
-
(2007)
J Cell Biol
, vol.176
, Issue.7
, pp. 929-939
-
-
Paronetto, MP1
-
93
-
-
77950524790
-
The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy
-
93. S Pedrotti 2010 The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy EMBO J 29 7 1235 1247 20186123 1:CAS:528:DC%2BC3cXitFemsbw%3D 10.1038/emboj.2010.19 Pedrotti S et al (2010) The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. EMBO J 29(7):1235–1247
-
(2010)
EMBO J
, vol.29
, Issue.7
, pp. 1235-1247
-
-
Pedrotti, S1
-
94
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
94. N Roy 1995 The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy Cell 80 1 167 178 7813013 1:CAS:528:DyaK2MXjtFegu78%3D 10.1016/0092-8674(95)90461-1 Roy N et al (1995) The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80(1):167–178
-
(1995)
Cell
, vol.80
, Issue.1
, pp. 167-178
-
-
Roy, N1
-
95
-
-
0029853107
-
Deletion analysis of the SMN and NAIP genes in Kuwaiti patients with spinal muscular atrophy
-
95. E Samilchuk 1996 Deletion analysis of the SMN and NAIP genes in Kuwaiti patients with spinal muscular atrophy Hum Genet 98 5 524 527 8882869 1:CAS:528:DyaK28XntVCnuro%3D 10.1007/s004390050253 Samilchuk E et al (1996) Deletion analysis of the SMN and NAIP genes in Kuwaiti patients with spinal muscular atrophy. Hum Genet 98(5):524–527
-
(1996)
Hum Genet
, vol.98
, Issue.5
, pp. 524-527
-
-
Samilchuk, E1
-
96
-
-
0030068764
-
Deletion analysis of SMN and NAIP genes in spinal muscular atrophy Italian families
-
96. F Capon 1996 Deletion analysis of SMN and NAIP genes in spinal muscular atrophy Italian families Muscle Nerve 19 3 378 380 8606706 1:STN:280:DyaK287nvFehtQ%3D%3D 10.1002/(SICI)1097-4598(199603)19:3<378::AID-MUS17>3.0.CO;2-O Capon F et al (1996) Deletion analysis of SMN and NAIP genes in spinal muscular atrophy Italian families. Muscle Nerve 19(3):378–380
-
(1996)
Muscle Nerve
, vol.19
, Issue.3
, pp. 378-380
-
-
Capon, F1
-
97
-
-
0031419876
-
Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents
-
97. JG Chang 1997 Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents Hum Genet 100 5–6 577 581 9341874 1:CAS:528:DyaK2sXlvFOmuro%3D 10.1007/s004390050555 Chang JG et al (1997) Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents. Hum Genet 100(5–6):577–581
-
(1997)
Hum Genet
, vol.100
, Issue.5–6
, pp. 577-581
-
-
Chang, JG1
-
98
-
-
0035885785
-
Molecular analysis of SMN, NAIP and P44 genes of SMA patients and their families
-
98. CH Tsai 2001 Molecular analysis of SMN, NAIP and P44 genes of SMA patients and their families J Neurol Sci 190 1–2 35 40 11574104 1:CAS:528:DC%2BD3MXntV2jtb8%3D 10.1016/S0022-510X(01)00574-3 Tsai CH et al (2001) Molecular analysis of SMN, NAIP and P44 genes of SMA patients and their families. J Neurol Sci 190(1–2):35–40
-
(2001)
J Neurol Sci
, vol.190
, Issue.1–2
, pp. 35-40
-
-
Tsai, CH1
-
99
-
-
20844453931
-
Study of survival of motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) gene deletions in SMA patients
-
99. A Kesari 2005 Study of survival of motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) gene deletions in SMA patients J Neurol 252 6 667 671 15772743 1:CAS:528:DC%2BD2MXmvVaqsrs%3D 10.1007/s00415-005-0714-2 Kesari A et al (2005) Study of survival of motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) gene deletions in SMA patients. J Neurol 252(6):667–671
-
(2005)
J Neurol
, vol.252
, Issue.6
, pp. 667-671
-
-
Kesari, A1
-
100
-
-
57349199403
-
Combination of SMN2 copy number and NAIP deletion predicts disease severity in spinal muscular atrophy
-
100. MS Watihayati 2009 Combination of SMN2 copy number and NAIP deletion predicts disease severity in spinal muscular atrophy Brain Dev 31 1 42 45 18842367 10.1016/j.braindev.2008.08.012 Watihayati MS et al (2009) Combination of SMN2 copy number and NAIP deletion predicts disease severity in spinal muscular atrophy. Brain Dev 31(1):42–45
-
(2009)
Brain Dev
, vol.31
, Issue.1
, pp. 42-45
-
-
Watihayati, MS1
-
101
-
-
0037088904
-
The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7
-
101. JK Maier 2002 The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7 J Neurosci 22 6 2035 2043 11896143 1:CAS:528:DC%2BD38XisVegsL8%3D Maier JK et al (2002) The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7. J Neurosci 22(6):2035–2043
-
(2002)
J Neurosci
, vol.22
, Issue.6
, pp. 2035-2043
-
-
Maier, JK1
-
102
-
-
0035673909
-
Neuronal apoptosis inhibitory protein expression after traumatic brain injury in the mouse
-
102. JS Hutchison 2001 Neuronal apoptosis inhibitory protein expression after traumatic brain injury in the mouse J Neurotrauma 18 12 1333 1347 11780864 1:STN:280:DC%2BD38%2FlsFegsQ%3D%3D 10.1089/08977150152725632 Hutchison JS et al (2001) Neuronal apoptosis inhibitory protein expression after traumatic brain injury in the mouse. J Neurotrauma 18(12):1333–1347
-
(2001)
J Neurotrauma
, vol.18
, Issue.12
, pp. 1333-1347
-
-
Hutchison, JS1
-
103
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
103. P Liston 1996 Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes Nature 379 6563 349 353 8552191 1:CAS:528:DyaK28XotVOmug%3D%3D 10.1038/379349a0 Liston P et al (1996) Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 379(6563):349–353
-
(1996)
Nature
, vol.379
, Issue.6563
, pp. 349-353
-
-
Liston, P1
-
104
-
-
0034087982
-
IAP family proteins delay motoneuron cell death in vivo
-
104. D Perrelet 2000 IAP family proteins delay motoneuron cell death in vivo Eur J Neurosci 12 6 2059 2067 10886345 1:STN:280:DC%2BD3czpt1SrtQ%3D%3D 10.1046/j.1460-9568.2000.00098.x Perrelet D et al (2000) IAP family proteins delay motoneuron cell death in vivo. Eur J Neurosci 12(6):2059–2067
-
(2000)
Eur J Neurosci
, vol.12
, Issue.6
, pp. 2059-2067
-
-
Perrelet, D1
-
105
-
-
0034088845
-
The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury
-
105. M Holcik 2000 The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury Proc Natl Acad Sci USA 97 5 2286 2290 10681452 1:CAS:528:DC%2BD3cXhslKhtb4%3D 10.1073/pnas.040469797 Holcik M et al (2000) The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury. Proc Natl Acad Sci USA 97(5):2286–2290
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.5
, pp. 2286-2290
-
-
Holcik, M1
-
106
-
-
0034641848
-
The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells
-
106. R Gotz 2000 The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells Hum Mol Genet 9 17 2479 2489 11030753 1:CAS:528:DC%2BD3cXnslGqsr8%3D 10.1093/hmg/9.17.2479 Gotz R et al (2000) The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells. Hum Mol Genet 9(17):2479–2489
-
(2000)
Hum Mol Genet
, vol.9
, Issue.17
, pp. 2479-2489
-
-
Gotz, R1
-
107
-
-
85047689522
-
Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy
-
107. M Azzouz 2004 Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy J Clin Invest 114 12 1726 1731 15599397 1:CAS:528:DC%2BD2cXhtFaiur7P Azzouz M et al (2004) Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy. J Clin Invest 114(12):1726–1731
-
(2004)
J Clin Invest
, vol.114
, Issue.12
, pp. 1726-1731
-
-
Azzouz, M1
-
108
-
-
77749249680
-
Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN
-
108. KD Foust 2010 Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN Nat Biotechnol 28 3 271 274 20190738 1:CAS:528:DC%2BC3cXisFelurs%3D 10.1038/nbt.1610 Foust KD et al (2010) Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN. Nat Biotechnol 28(3):271–274
-
(2010)
Nat Biotechnol
, vol.28
, Issue.3
, pp. 271-274
-
-
Foust, KD1
-
109
-
-
0038688782
-
Antisense oligonucleotides for cancer therapy—an overview
-
109. RA Stahel U Zangemeister-Wittke 2003 Antisense oligonucleotides for cancer therapy—an overview Lung Cancer 41 Suppl 1 S81 S88 12867066 10.1016/S0169-5002(03)00147-8 Stahel RA, Zangemeister-Wittke U (2003) Antisense oligonucleotides for cancer therapy—an overview. Lung Cancer 41(Suppl 1):S81–S88
-
(2003)
Lung Cancer
, vol.41
, Issue.Suppl 1
, pp. S81-S88
-
-
Stahel, RA1
Zangemeister-Wittke, U2
-
110
-
-
37549034298
-
Local dystrophin restoration with antisense oligonucleotide PRO051
-
110. JC Deutekom van 2007 Local dystrophin restoration with antisense oligonucleotide PRO051 N Engl J Med 357 26 2677 2686 18160687 10.1056/NEJMoa073108 van Deutekom JC et al (2007) Local dystrophin restoration with antisense oligonucleotide PRO051. N Engl J Med 357(26):2677–2686
-
(2007)
N Engl J Med
, vol.357
, Issue.26
, pp. 2677-2686
-
-
Deutekom, JC1
-
111
-
-
80051690306
-
Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study
-
111. S Cirak 2011 Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study Lancet 378 9791 595 605 21784508 1:CAS:528:DC%2BC3MXhtVWmtL%2FO 10.1016/S0140-6736(11)60756-3 Cirak S et al (2011) Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study. Lancet 378(9791):595–605
-
(2011)
Lancet
, vol.378
, Issue.9791
, pp. 595-605
-
-
Cirak, S1
-
112
-
-
34247388843
-
Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon
-
112. Y Hua 2007 Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon PLoS Biol 5 4 e73 17355180 10.1371/journal.pbio.0050073 1:CAS:528:DC%2BD2sXksFSmtrk%3D Hua Y et al (2007) Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon. PLoS Biol 5(4):e73
-
(2007)
PLoS Biol
, vol.5
, Issue.4
, pp. e73
-
-
Hua, Y1
-
113
-
-
79952348568
-
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy
-
113. MA Passini 2011 Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy Sci Transl Med 3 72 72ra18 21368223 10.1126/scitranslmed.3001777 Passini MA et al (2011) Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy. Sci Transl Med 3(72):72ra18
-
(2011)
Sci Transl Med
, vol.3
, Issue.72
, pp. 72ra18
-
-
Passini, MA1
-
114
-
-
72749096700
-
Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS
-
114. ST Lim M Airavaara BK Harvey 2010 Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS Pharmacol Res 61 1 14 26 19840853 1:CAS:528:DC%2BC3cXotlOk 10.1016/j.phrs.2009.10.002 Lim ST, Airavaara M, Harvey BK (2010) Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS. Pharmacol Res 61(1):14–26
-
(2010)
Pharmacol Res
, vol.61
, Issue.1
, pp. 14-26
-
-
Lim, ST1
Airavaara, M2
Harvey, BK3
-
115
-
-
3142587121
-
Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction
-
115. Y Ruixing Y Dezhai L Jiaquan 2004 Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction J Med Invest 51 1–2 29 37 15000253 Ruixing Y, Dezhai Y, Jiaquan L (2004) Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction. J Med Invest 51(1–2):29–37
-
(2004)
J Med Invest
, vol.51
, Issue.1–2
, pp. 29-37
-
-
Ruixing, Y1
Dezhai, Y2
Jiaquan, L3
-
116
-
-
23744439101
-
Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro
-
116. TC Wen 2005 Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro Neurosci Lett 387 1 38 42 16084018 1:CAS:528:DC%2BD2MXns1WmtLY%3D 10.1016/j.neulet.2005.07.018 Wen TC et al (2005) Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro. Neurosci Lett 387(1):38–42
-
(2005)
Neurosci Lett
, vol.387
, Issue.1
, pp. 38-42
-
-
Wen, TC1
-
117
-
-
0035444173
-
Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice
-
117. T Bordet 2001 Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice Hum Mol Genet 10 18 1925 1933 11555629 1:CAS:528:DC%2BD3MXntlSgsbo%3D 10.1093/hmg/10.18.1925 Bordet T et al (2001) Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice. Hum Mol Genet 10(18):1925–1933
-
(2001)
Hum Mol Genet
, vol.10
, Issue.18
, pp. 1925-1933
-
-
Bordet, T1
-
118
-
-
0037669048
-
Therapeutic benefits of cardiotrophin-1 gene transfer in a mouse model of spinal muscular atrophy
-
118. JC Lesbordes 2003 Therapeutic benefits of cardiotrophin-1 gene transfer in a mouse model of spinal muscular atrophy Hum Mol Genet 12 11 1233 1239 12761038 1:CAS:528:DC%2BD3sXkt1Wru7o%3D 10.1093/hmg/ddg143 Lesbordes JC et al (2003) Therapeutic benefits of cardiotrophin-1 gene transfer in a mouse model of spinal muscular atrophy. Hum Mol Genet 12(11):1233–1239
-
(2003)
Hum Mol Genet
, vol.12
, Issue.11
, pp. 1233-1239
-
-
Lesbordes, JC1
-
119
-
-
77950140276
-
Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro
-
119. H Peng 2010 Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro J Neurosci Res 88 5 1041 1051 19859964 1:CAS:528:DC%2BC3cXhvF2rtro%3D Peng H et al (2010) Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro. J Neurosci Res 88(5):1041–1051
-
(2010)
J Neurosci Res
, vol.88
, Issue.5
, pp. 1041-1051
-
-
Peng, H1
-
120
-
-
33750492639
-
IGF-I specifically enhances axon outgrowth of corticospinal motor neurons
-
120. PH Ozdinler JD Macklis 2006 IGF-I specifically enhances axon outgrowth of corticospinal motor neurons Nat Neurosci 9 11 1371 1381 17057708 10.1038/nn1789 1:CAS:528:DC%2BD28XhtFaksrbE Ozdinler PH, Macklis JD (2006) IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. Nat Neurosci 9(11):1371–1381
-
(2006)
Nat Neurosci
, vol.9
, Issue.11
, pp. 1371-1381
-
-
Ozdinler, PH1
Macklis, JD2
-
121
-
-
68149180778
-
Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy
-
121. I Palazzolo 2009 Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy Neuron 63 3 316 328 19679072 1:CAS:528:DC%2BD1MXhtFyhsb%2FE 10.1016/j.neuron.2009.07.019 Palazzolo I et al (2009) Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy. Neuron 63(3):316–328
-
(2009)
Neuron
, vol.63
, Issue.3
, pp. 316-328
-
-
Palazzolo, I1
-
122
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
122. BK Kaspar 2003 Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model Science 301 5634 839 842 12907804 1:CAS:528:DC%2BD3sXmtVGqs7c%3D 10.1126/science.1086137 Kaspar BK et al (2003) Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 301(5634):839–842
-
(2003)
Science
, vol.301
, Issue.5634
, pp. 839-842
-
-
Kaspar, BK1
-
123
-
-
79954534432
-
Increased IGF-1 in muscle modulates the phenotype of severe SMA mice
-
123. M Bosch-Marce 2011 Increased IGF-1 in muscle modulates the phenotype of severe SMA mice Hum Mol Genet 20 9 1844 1853 21325354 1:CAS:528:DC%2BC3MXksFSkurY%3D 10.1093/hmg/ddr067 Bosch-Marce M et al (2011) Increased IGF-1 in muscle modulates the phenotype of severe SMA mice. Hum Mol Genet 20(9):1844–1853
-
(2011)
Hum Mol Genet
, vol.20
, Issue.9
, pp. 1844-1853
-
-
Bosch-Marce, M1
-
124
-
-
77951201412
-
CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy
-
124. MA Passini 2010 CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy J Clin Invest 120 4 1253 1264 20234094 1:CAS:528:DC%2BC3cXksVChsbs%3D 10.1172/JCI41615 Passini MA et al (2010) CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy. J Clin Invest 120(4):1253–1264
-
(2010)
J Clin Invest
, vol.120
, Issue.4
, pp. 1253-1264
-
-
Passini, MA1
-
125
-
-
78751700314
-
Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice
-
125. E Dominguez 2011 Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice Hum Mol Genet 20 4 681 693 21118896 1:CAS:528:DC%2BC3MXpsFyhsw%3D%3D 10.1093/hmg/ddq514 Dominguez E et al (2011) Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice. Hum Mol Genet 20(4):681–693
-
(2011)
Hum Mol Genet
, vol.20
, Issue.4
, pp. 681-693
-
-
Dominguez, E1
-
126
-
-
84858256924
-
A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse
-
126. PN Porensky 2012 A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse Hum Mol Genet 21 7 1625 1638 22186025 1:CAS:528:DC%2BC38Xjs1Srt7c%3D 10.1093/hmg/ddr600 Porensky PN et al (2012) A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse. Hum Mol Genet 21(7):1625–1638
-
(2012)
Hum Mol Genet
, vol.21
, Issue.7
, pp. 1625-1638
-
-
Porensky, PN1
-
127
-
-
81955167497
-
IGF-1 delivery to CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice
-
127. LK Tsai 2012 IGF-1 delivery to CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice Neurobiol Dis 45 1 272 279 21884794 1:CAS:528:DC%2BC3MXhsFGqsLjN 10.1016/j.nbd.2011.06.021 Tsai LK et al (2012) IGF-1 delivery to CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice. Neurobiol Dis 45(1):272–279
-
(2012)
Neurobiol Dis
, vol.45
, Issue.1
, pp. 272-279
-
-
Tsai, LK1
-
128
-
-
79951826869
-
Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy
-
128. M Shababi J Glascock CL Lorson 2011 Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy Hum Gene Ther 22 2 135 144 20804424 1:CAS:528:DC%2BC3MXitVOhsr0%3D 10.1089/hum.2010.114 Shababi M, Glascock J, Lorson CL (2011) Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy. Hum Gene Ther 22(2):135–144
-
(2011)
Hum Gene Ther
, vol.22
, Issue.2
, pp. 135-144
-
-
Shababi, M1
Glascock, J2
Lorson, CL3
-
129
-
-
39749168988
-
Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy
-
129. G Simic 2008 Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy Acta Neuropathol 115 3 313 326 18075747 10.1007/s00401-007-0327-1 Simic G et al (2008) Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy. Acta Neuropathol 115(3):313–326
-
(2008)
Acta Neuropathol
, vol.115
, Issue.3
, pp. 313-326
-
-
Simic, G1
-
130
-
-
79954631444
-
A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons
-
130. A Garcera 2011 A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons Neurobiol Dis 42 3 415 426 21333739 1:CAS:528:DC%2BC3MXkvVGlu70%3D 10.1016/j.nbd.2011.02.003 Garcera A et al (2011) A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons. Neurobiol Dis 42(3):415–426
-
(2011)
Neurobiol Dis
, vol.42
, Issue.3
, pp. 415-426
-
-
Garcera, A1
-
131
-
-
79960985352
-
Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway
-
131. F Farooq 2011 Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway J Clin Invest 121 8 3042 3050 21785216 1:CAS:528:DC%2BC3MXhtVejur3M 10.1172/JCI46276 Farooq F et al (2011) Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway. J Clin Invest 121(8):3042–3050
-
(2011)
J Clin Invest
, vol.121
, Issue.8
, pp. 3042-3050
-
-
Farooq, F1
-
132
-
-
79960560680
-
A screen for regulators of survival of motor neuron protein levels
-
132. NR Makhortova 2011 A screen for regulators of survival of motor neuron protein levels Nat Chem Biol 7 8 544 552 21685895 1:CAS:528:DC%2BC3MXnslSlu7w%3D 10.1038/nchembio.595 Makhortova NR et al (2011) A screen for regulators of survival of motor neuron protein levels. Nat Chem Biol 7(8):544–552
-
(2011)
Nat Chem Biol
, vol.7
, Issue.8
, pp. 544-552
-
-
Makhortova, NR1
-
133
-
-
34047124905
-
Stat5 constitutive activation rescues defects in spinal muscular atrophy
-
133. CH Ting 2007 Stat5 constitutive activation rescues defects in spinal muscular atrophy Hum Mol Genet 16 5 499 514 17220171 1:CAS:528:DC%2BD2sXjslersb4%3D 10.1093/hmg/ddl482 Ting CH et al (2007) Stat5 constitutive activation rescues defects in spinal muscular atrophy. Hum Mol Genet 16(5):499–514
-
(2007)
Hum Mol Genet
, vol.16
, Issue.5
, pp. 499-514
-
-
Ting, CH1
-
134
-
-
0034641710
-
Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury
-
134. ML Brines 2000 Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury Proc Natl Acad Sci USA 97 19 10526 10531 10984541 1:CAS:528:DC%2BD3cXms1Crtrk%3D 10.1073/pnas.97.19.10526 Brines ML et al (2000) Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA 97(19):10526–10531
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.19
, pp. 10526-10531
-
-
Brines, ML1
-
135
-
-
70349234479
-
The efficacy of erythropoietin and its analogues in animal stroke models: a meta-analysis
-
135. J Minnerup 2009 The efficacy of erythropoietin and its analogues in animal stroke models: a meta-analysis Stroke 40 9 3113 3120 19542052 1:CAS:528:DC%2BD1MXhtVSisL3O 10.1161/STROKEAHA.109.555789 Minnerup J et al (2009) The efficacy of erythropoietin and its analogues in animal stroke models: a meta-analysis. Stroke 40(9):3113–3120
-
(2009)
Stroke
, vol.40
, Issue.9
, pp. 3113-3120
-
-
Minnerup, J1
-
136
-
-
70349299783
-
Erythropoietin exerts anti-epileptic effects with the suppression of aberrant new cell formation in the dentate gyrus and upregulation of neuropeptide Y in seizure model of rats
-
136. A Kondo 2009 Erythropoietin exerts anti-epileptic effects with the suppression of aberrant new cell formation in the dentate gyrus and upregulation of neuropeptide Y in seizure model of rats Brain Res 1296 127 136 19695235 1:CAS:528:DC%2BD1MXhtFyqsb%2FE 10.1016/j.brainres.2009.08.025 Kondo A et al (2009) Erythropoietin exerts anti-epileptic effects with the suppression of aberrant new cell formation in the dentate gyrus and upregulation of neuropeptide Y in seizure model of rats. Brain Res 1296:127–136
-
(2009)
Brain Res
, vol.1296
, pp. 127-136
-
-
Kondo, A1
-
137
-
-
3042725549
-
Derivatives of erythropoietin that are tissue protective but not erythropoietic
-
137. M Leist 2004 Derivatives of erythropoietin that are tissue protective but not erythropoietic Science 305 5681 239 242 15247477 1:CAS:528:DC%2BD2cXlsV2gsbo%3D 10.1126/science.1098313 Leist M et al (2004) Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science 305(5681):239–242
-
(2004)
Science
, vol.305
, Issue.5681
, pp. 239-242
-
-
Leist, M1
-
138
-
-
33847687265
-
Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model
-
138. JF Grunfeld 2007 Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model Exp Neurol 204 1 260 263 17174305 1:CAS:528:DC%2BD2sXisVWntr4%3D 10.1016/j.expneurol.2006.11.002 Grunfeld JF et al (2007) Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model. Exp Neurol 204(1):260–263
-
(2007)
Exp Neurol
, vol.204
, Issue.1
, pp. 260-263
-
-
Grunfeld, JF1
-
139
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
139. JA Thomson 1998 Embryonic stem cell lines derived from human blastocysts Science 282 5391 1145 1147 9804556 1:CAS:528:DyaK1cXntleisLg%3D 10.1126/science.282.5391.1145 Thomson JA et al (1998) Embryonic stem cell lines derived from human blastocysts. Science 282(5391):1145–1147
-
(1998)
Science
, vol.282
, Issue.5391
, pp. 1145-1147
-
-
Thomson, JA1
-
140
-
-
77249088647
-
Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice
-
140. S Corti 2010 Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice Brain 133 Pt 2 465 481 20032086 10.1093/brain/awp318 Corti S et al (2010) Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice. Brain 133(Pt 2):465–481
-
(2010)
Brain
, vol.133
, Issue.Pt 2
, pp. 465-481
-
-
Corti, S1
-
141
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
141. AD Ebert 2009 Induced pluripotent stem cells from a spinal muscular atrophy patient Nature 457 7227 277 280 19098894 1:CAS:528:DC%2BD1MXlvFWnsw%3D%3D 10.1038/nature07677 Ebert AD et al (2009) Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457(7227):277–280
-
(2009)
Nature
, vol.457
, Issue.7227
, pp. 277-280
-
-
Ebert, AD1
-
142
-
-
0035859952
-
Treatment of spinal muscular atrophy by sodium butyrate
-
142. JG Chang 2001 Treatment of spinal muscular atrophy by sodium butyrate Proc Natl Acad Sci USA 98 17 9808 9813 11504946 1:CAS:528:DC%2BD3MXmtlCms7c%3D 10.1073/pnas.171105098 Chang JG et al (2001) Treatment of spinal muscular atrophy by sodium butyrate. Proc Natl Acad Sci USA 98(17):9808–9813
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.17
, pp. 9808-9813
-
-
Chang, JG1
-
143
-
-
0141506887
-
Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy
-
143. L Brichta 2003 Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy Hum Mol Genet 12 19 2481 2489 12915451 1:CAS:528:DC%2BD3sXnsVekt70%3D 10.1093/hmg/ddg256 Brichta L et al (2003) Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy. Hum Mol Genet 12(19):2481–2489
-
(2003)
Hum Mol Genet
, vol.12
, Issue.19
, pp. 2481-2489
-
-
Brichta, L1
-
144
-
-
10744229981
-
Phenylbutyrate increases SMN expression in vitro: relevance for treatment of spinal muscular atrophy
-
144. C Andreassi 2004 Phenylbutyrate increases SMN expression in vitro: relevance for treatment of spinal muscular atrophy Eur J Hum Genet 12 1 59 65 14560316 1:CAS:528:DC%2BD2cXls1Gi 10.1038/sj.ejhg.5201102 Andreassi C et al (2004) Phenylbutyrate increases SMN expression in vitro: relevance for treatment of spinal muscular atrophy. Eur J Hum Genet 12(1):59–65
-
(2004)
Eur J Hum Genet
, vol.12
, Issue.1
, pp. 59-65
-
-
Andreassi, C1
-
145
-
-
0242290062
-
Valproic acid increases SMN levels in spinal muscular atrophy patient cells
-
145. CJ Sumner 2003 Valproic acid increases SMN levels in spinal muscular atrophy patient cells Ann Neurol 54 5 647 654 14595654 1:CAS:528:DC%2BD3sXpsFChsb4%3D 10.1002/ana.10743 Sumner CJ et al (2003) Valproic acid increases SMN levels in spinal muscular atrophy patient cells. Ann Neurol 54(5):647–654
-
(2003)
Ann Neurol
, vol.54
, Issue.5
, pp. 647-654
-
-
Sumner, CJ1
-
146
-
-
55849106634
-
Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition
-
146. HL Narver 2008 Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition Ann Neurol 64 4 465 470 18661558 10.1002/ana.21449 Narver HL et al (2008) Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. Ann Neurol 64(4):465–470
-
(2008)
Ann Neurol
, vol.64
, Issue.4
, pp. 465-470
-
-
Narver, HL1
-
147
-
-
0035971729
-
Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors
-
147. AJ Grierson CE Shaw CC Miller 2001 Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors Biochim Biophys Acta 1536 1 13 20 11335100 1:CAS:528:DC%2BD3MXjtFGiu74%3D 10.1016/S0925-4439(01)00029-1 Grierson AJ, Shaw CE, Miller CC (2001) Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors. Biochim Biophys Acta 1536(1):13–20
-
(2001)
Biochim Biophys Acta
, vol.1536
, Issue.1
, pp. 13-20
-
-
Grierson, AJ1
Shaw, CE2
Miller, CC3
-
148
-
-
33846114574
-
Randomized, double-blind, placebo-controlled trial of phenylbutyrate in spinal muscular atrophy
-
148. E Mercuri 2007 Randomized, double-blind, placebo-controlled trial of phenylbutyrate in spinal muscular atrophy Neurology 68 1 51 55 17082463 1:CAS:528:DC%2BD28XhtlCht7jE 10.1212/01.wnl.0000249142.82285.d6 Mercuri E et al (2007) Randomized, double-blind, placebo-controlled trial of phenylbutyrate in spinal muscular atrophy. Neurology 68(1):51–55
-
(2007)
Neurology
, vol.68
, Issue.1
, pp. 51-55
-
-
Mercuri, E1
-
149
-
-
77957929588
-
SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy
-
149. KJ Swoboda 2010 SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy PLoS One 5 8 e12140 20808854 10.1371/journal.pone.0012140 1:CAS:528:DC%2BC3cXhtVOnu7jN Swoboda KJ et al (2010) SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy. PLoS One 5(8):e12140
-
(2010)
PLoS One
, vol.5
, Issue.8
, pp. e12140
-
-
Swoboda, KJ1
-
150
-
-
79959988589
-
SMA CARNIVAL TRIAL PART II: a prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy
-
150. JT Kissel 2011 SMA CARNIVAL TRIAL PART II: a prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy PLoS One 6 7 e21296 21754985 1:CAS:528:DC%2BC3MXpsVams74%3D 10.1371/journal.pone.0021296 Kissel JT et al (2011) SMA CARNIVAL TRIAL PART II: a prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy. PLoS One 6(7):e21296
-
(2011)
PLoS One
, vol.6
, Issue.7
, pp. e21296
-
-
Kissel, JT1
-
151
-
-
23244458683
-
Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells
-
151. SM Grzeschik 2005 Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells Ann Neurol 58 2 194 202 16049920 1:CAS:528:DC%2BD2MXps1Cgtbc%3D 10.1002/ana.20548 Grzeschik SM et al (2005) Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells. Ann Neurol 58(2):194–202
-
(2005)
Ann Neurol
, vol.58
, Issue.2
, pp. 194-202
-
-
Grzeschik, SM1
-
152
-
-
78650809695
-
Randomized, double-blind, placebo-controlled trial of hydroxyurea in spinal muscular atrophy
-
152. TH Chen 2010 Randomized, double-blind, placebo-controlled trial of hydroxyurea in spinal muscular atrophy Neurology 75 24 2190 2197 21172842 1:CAS:528:DC%2BC3cXhsFKisrrM 10.1212/WNL.0b013e3182020332 Chen TH et al (2010) Randomized, double-blind, placebo-controlled trial of hydroxyurea in spinal muscular atrophy. Neurology 75(24):2190–2197
-
(2010)
Neurology
, vol.75
, Issue.24
, pp. 2190-2197
-
-
Chen, TH1
-
153
-
-
80455173951
-
Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders
-
153. AK Bevan 2011 Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders Mol Ther 19 11 1971 1980 21811247 1:CAS:528:DC%2BC3MXpslShu7o%3D 10.1038/mt.2011.157 Bevan AK et al (2011) Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders. Mol Ther 19(11):1971–1980
-
(2011)
Mol Ther
, vol.19
, Issue.11
, pp. 1971-1980
-
-
Bevan, AK1
-
154
-
-
0035886619
-
A placebo-controlled trial of gabapentin in spinal muscular atrophy
-
154. RG Miller 2001 A placebo-controlled trial of gabapentin in spinal muscular atrophy J Neurol Sci 191 1–2 127 131 11677003 1:CAS:528:DC%2BD3MXnslCitbY%3D 10.1016/S0022-510X(01)00632-3 Miller RG et al (2001) A placebo-controlled trial of gabapentin in spinal muscular atrophy. J Neurol Sci 191(1–2):127–131
-
(2001)
J Neurol Sci
, vol.191
, Issue.1–2
, pp. 127-131
-
-
Miller, RG1
-
155
-
-
85121078429
-
-
155. ALS CNTF Treatment Study Group (1996) A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. Neurology 46:1244–1249
-
-
-
-
156
-
-
85121078459
-
-
156. Kasarkis E (1999) A controlled trial of recombinant methionyl human BDNF in 1097 ALS: the BDNF Study Group (Phase III). Neurology 52(7):1427–33
-
-
-
-
157
-
-
21344433902
-
Autonomic dysfunction in ALS: a preliminary study on the effects of intrathecal BDNF
-
157. M Beck 2005 Autonomic dysfunction in ALS: a preliminary study on the effects of intrathecal BDNF Amyotroph Lateral Scler Other Motor Neuron Disord 6 2 100 103 16036433 1:CAS:528:DC%2BD2MXltFymu7Y%3D 10.1080/14660820510028412 Beck M et al (2005) Autonomic dysfunction in ALS: a preliminary study on the effects of intrathecal BDNF. Amyotroph Lateral Scler Other Motor Neuron Disord 6(2):100–103
-
(2005)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.6
, Issue.2
, pp. 100-103
-
-
Beck, M1
-
158
-
-
58149242839
-
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
-
158. EJ Sorenson 2008 Subcutaneous IGF-1 is not beneficial in 2-year ALS trial Neurology 71 22 1770 1775 19029516 1:CAS:528:DC%2BD1cXhtlylurjK 10.1212/01.wnl.0000335970.78664.36 Sorenson EJ et al (2008) Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology 71(22):1770–1775
-
(2008)
Neurology
, vol.71
, Issue.22
, pp. 1770-1775
-
-
Sorenson, EJ1
-
159
-
-
0028243306
-
The protein tyrosine kinase P59fyn is associated with prolactin (PRL) receptor and is activated by PRL stimulation of T-lymphocytes
-
159. CV Clevenger MV Medaglia 1994 The protein tyrosine kinase P59fyn is associated with prolactin (PRL) receptor and is activated by PRL stimulation of T-lymphocytes Mol Endocrinol 8 6 674 681 7935483 1:CAS:528:DyaK2cXkt1Ogtbk%3D 10.1210/me.8.6.674 Clevenger CV, Medaglia MV (1994) The protein tyrosine kinase P59fyn is associated with prolactin (PRL) receptor and is activated by PRL stimulation of T-lymphocytes. Mol Endocrinol 8(6):674–681
-
(1994)
Mol Endocrinol
, vol.8
, Issue.6
, pp. 674-681
-
-
Clevenger, CV1
Medaglia, MV2
|