메뉴 건너뛰기




Volumn 19, Issue 10, 1999, Pages 6554-6565

Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner

Author keywords

[No Author keywords available]

Indexed keywords

SMALL NUCLEAR RIBONUCLEOPROTEIN;

EID: 0032862988     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.10.6554     Document Type: Article
Times cited : (117)

References (45)
  • 2
    • 0029054375 scopus 로고
    • Identification and characterization of Uss1p (Sdb23p): A novel U6 snRNA-associated protein with significant similarity to core proteins of small nuclear ribonucleoproteins
    • Cooper, M., L. H. Johnston, and J. D. Beggs. 1995. Identification and characterization of Uss1p (Sdb23p): a novel U6 snRNA-associated protein with significant similarity to core proteins of small nuclear ribonucleoproteins. EMBO J. 14:2066-2075.
    • (1995) EMBO J. , vol.14 , pp. 2066-2075
    • Cooper, M.1    Johnston, L.H.2    Beggs, J.D.3
  • 3
    • 0030928716 scopus 로고    scopus 로고
    • The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis
    • Fischer, U., Q. Liu, and G. Dreyfuss. 1997. The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. Cell 90:1023-1029.
    • (1997) Cell , vol.90 , pp. 1023-1029
    • Fischer, U.1    Liu, Q.2    Dreyfuss, G.3
  • 4
    • 0024999077 scopus 로고
    • An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus
    • Fischer, U., and R. Lührmann. 1990. An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus. Science 249:786-790.
    • (1990) Science , vol.249 , pp. 786-790
    • Fischer, U.1    Lührmann, R.2
  • 5
    • 0027396947 scopus 로고
    • Nucleocytoplasmic transport of U snRNPs: Definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap
    • Fischer, U., V. Sumpter, M. Sekine, T. Satoh, and R. Lührmann. 1993. Nucleocytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap. EMBO J. 12:573-583.
    • (1993) EMBO J. , vol.12 , pp. 573-583
    • Fischer, U.1    Sumpter, V.2    Sekine, M.3    Satoh, T.4    Lührmann, R.5
  • 6
    • 0022133408 scopus 로고
    • Small nuclear ribonucleoprotein particle assembly in vivo: Demonstration of a 6S RNA-free core precursor and posttranslational modification
    • Fisher, D. E., G. E. Conner, W. H. Reeves, R. Wisniewolski, and G. Blobel. 1985. Small nuclear ribonucleoprotein particle assembly in vivo: demonstration of a 6S RNA-free core precursor and posttranslational modification. Cell 42:751-758.
    • (1985) Cell , vol.42 , pp. 751-758
    • Fisher, D.E.1    Conner, G.E.2    Reeves, W.H.3    Wisniewolski, R.4    Blobel, G.5
  • 7
    • 0019878376 scopus 로고
    • Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis
    • Fried, M., and D. M. Crothers. 1981. Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res. 9:6505-6525.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 6505-6525
    • Fried, M.1    Crothers, D.M.2
  • 8
    • 0033104890 scopus 로고    scopus 로고
    • Thirteen anti-Sm monoclonal antibodies immunoprecipitate the three cytoplasmic snRNP core protein precursors in six distinct subsets
    • Fury, M., J. Andersen, P. Ponda, R. Aimes, and G. W. Zieve. 1999. Thirteen anti-Sm monoclonal antibodies immunoprecipitate the three cytoplasmic snRNP core protein precursors in six distinct subsets. J. Autoimmunity 12:91-100.
    • (1999) J. Autoimmunity , vol.12 , pp. 91-100
    • Fury, M.1    Andersen, J.2    Ponda, P.3    Aimes, R.4    Zieve, G.W.5
  • 9
    • 0031039644 scopus 로고    scopus 로고
    • In vivo selection of RNAs that localize in the nucleus
    • Grimm, C., E. Lund, and J. E. Dahlberg. 1997. In vivo selection of RNAs that localize in the nucleus. EMBO J. 16:793-806.
    • (1997) EMBO J. , vol.16 , pp. 793-806
    • Grimm, C.1    Lund, E.2    Dahlberg, J.E.3
  • 10
    • 0027478073 scopus 로고
    • The low abundance of U7 snRNA is partly determined by its Sm binding site
    • Grimm, C., B. Stefanovic, and D. Schümperli. 1993. The low abundance of U7 snRNA is partly determined by its Sm binding site. EMBO J. 12:1229-1238.
    • (1993) EMBO J. , vol.12 , pp. 1229-1238
    • Grimm, C.1    Stefanovic, B.2    Schümperli, D.3
  • 11
    • 0025007910 scopus 로고
    • The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal
    • Hamm, J., E. Darzynkiewicz, S. M. Tahara, and I. W. Mattaj. 1990. The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal. Cell 62:569-577.
    • (1990) Cell , vol.62 , pp. 569-577
    • Hamm, J.1    Darzynkiewicz, E.2    Tahara, S.M.3    Mattaj, I.W.4
  • 12
    • 0023440915 scopus 로고
    • In vitro assembly of U1 snRNPs
    • Hamm, J., M. Kazmaier, and I. W. Mattaj. 1987. In vitro assembly of U1 snRNPs. EMBO J. 6:3479-3485.
    • (1987) EMBO J. , vol.6 , pp. 3479-3485
    • Hamm, J.1    Kazmaier, M.2    Mattaj, I.W.3
  • 14
    • 0033534531 scopus 로고    scopus 로고
    • An unusual chemical reactivity of sm site adenosines strongly correlates with proper assembly of core U snRNP particles
    • Hartmuth, K., V. A. Raker, J. Huber, C. Branlant, and R. Lührmann. 1999. An unusual chemical reactivity of Sm site adenosines strongly correlates with proper assembly of core U snRNP particles. J. Mol. Biol. 285:133-147.
    • (1999) J. Mol. Biol. , vol.285 , pp. 133-147
    • Hartmuth, K.1    Raker, V.A.2    Huber, J.3    Branlant, C.4    Lührmann, R.5
  • 15
    • 0026744453 scopus 로고
    • Direct binding of small nuclear ribonucleoprotein G to the Sm site of small nuclear RNA. Ultraviolet light cross-linking of protein G to the AAU stretch within the Sm site (AAUUUGUGG) of U1 small nuclear ribonucleoprotein reconstituted in vitro
    • Heinrichs, V., W. Hackl, and R. Lührmann. 1992. Direct binding of small nuclear ribonucleoprotein G to the Sm site of small nuclear RNA. Ultraviolet light cross-linking of protein G to the AAU stretch within the Sm site (AAUUUGUGG) of U1 small nuclear ribonucleoprotein reconstituted in vitro. J. Mol. Biol. 227:15-28.
    • (1992) J. Mol. Biol. , vol.227 , pp. 15-28
    • Heinrichs, V.1    Hackl, W.2    Lührmann, R.3
  • 16
    • 0029054377 scopus 로고
    • snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in sm protein-protein interactions
    • Hermann, H., P. Fabrizio, V. A. Raker, K. Foulaki, H. Hornig, H. Brahms, and R. Lührmann. 1995. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions. EMBO J. 14:2076-2088.
    • (1995) EMBO J. , vol.14 , pp. 2076-2088
    • Hermann, H.1    Fabrizio, P.2    Raker, V.A.3    Foulaki, K.4    Hornig, H.5    Brahms, H.6    Lührmann, R.7
  • 17
    • 0028881597 scopus 로고
    • Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains
    • Hu, J., D. Xu, K. Schappert, Y. Xu, and J. D. Friesen. 1995. Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains. Mol. Cell. Biol. 15:1274-1285.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1274-1285
    • Hu, J.1    Xu, D.2    Schappert, K.3    Xu, Y.4    Friesen, J.D.5
  • 19
    • 0027393013 scopus 로고
    • The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical
    • Jarmolowski, A., and I. W. Mattaj. 1993. The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical. EMBO J. 12:223-232.
    • (1993) EMBO J. , vol.12 , pp. 223-232
    • Jarmolowski, A.1    Mattaj, I.W.2
  • 20
    • 0025288649 scopus 로고
    • Unexpected flexibility in an evolutionarily conserved protein-RNA interaction: Genetic analysis of the Sm binding site
    • Jones, M. H., and C. Guthrie. 1990. Unexpected flexibility in an evolutionarily conserved protein-RNA interaction: genetic analysis of the Sm binding site. EMBO J. 9:2555-2561.
    • (1990) EMBO J. , vol.9 , pp. 2555-2561
    • Jones, M.H.1    Guthrie, C.2
  • 21
    • 0033524941 scopus 로고    scopus 로고
    • Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs
    • Kambach, C., S. Walke, R. Young, J. M. Avis, E. de la Fortelle, V. A. Raker, R. Lührmann, J. Li, and K. Nagai. 1999. Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96:375-387.
    • (1999) Cell , vol.96 , pp. 375-387
    • Kambach, C.1    Walke, S.2    Young, R.3    Avis, J.M.4    De La Fortelle, E.5    Raker, V.A.6    Lührmann, R.7    Li, J.8    Nagai, K.9
  • 22
    • 0025254471 scopus 로고
    • Electron microscopy of small nuclear ribonucleoprotein (snRNP) particles U2 and U5: Evidence for a common structure-determining principle in the major U snRNP family
    • Kastner, B., M. Bach, and R. Lührmann. 1990. Electron microscopy of small nuclear ribonucleoprotein (snRNP) particles U2 and U5: evidence for a common structure-determining principle in the major U snRNP family. Proc. Natl. Acad. Sci. USA 87:1710-1714.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1710-1714
    • Kastner, B.1    Bach, M.2    Lührmann, R.3
  • 24
    • 0025027317 scopus 로고
    • Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5
    • Lehmeier, T., K. Foulaki, and R. Lührmann. 1990. Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5. Nucleic Acids Res. 18:6475-6484.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6475-6484
    • Lehmeier, T.1    Foulaki, K.2    Lührmann, R.3
  • 25
    • 0027988478 scopus 로고
    • cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: Evidence for a direct D1-D2 interaction
    • Lehmeier, T., V. A. Raker, H. Hermann, and R. Lührmann. 1994. cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction. Proc. Natl. Acad. Sci. USA 91:12317-12321.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12317-12321
    • Lehmeier, T.1    Raker, V.A.2    Hermann, H.3    Lührmann, R.4
  • 26
    • 0000341684 scopus 로고
    • Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus
    • Lerner, M. R., and J. A. Steitz. 1979. Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc. Natl. Acad. Sci. USA 76:5495-5499.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5495-5499
    • Lerner, M.R.1    Steitz, J.A.2
  • 27
    • 0020308857 scopus 로고
    • Structural organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells. Proteins interact closely with a similar structural domain of U1, U2, U4 and U5 small nuclear RNAs
    • Liautard, J. P., J. Sri-Widada, C. Brunel, and P. Jeanteur. 1982. Structural organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells. Proteins interact closely with a similar structural domain of U1, U2, U4 and U5 small nuclear RNAs. J. Mol. Biol. 162:623-643.
    • (1982) J. Mol. Biol. , vol.162 , pp. 623-643
    • Liautard, J.P.1    Sri-Widada, J.2    Brunel, C.3    Jeanteur, P.4
  • 28
    • 0030931727 scopus 로고    scopus 로고
    • The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins
    • Liu, Q., U. Fischer, F. Wang, and G. Dreyfuss. 1997. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell 90:1013-1021.
    • (1997) Cell , vol.90 , pp. 1013-1021
    • Liu, Q.1    Fischer, U.2    Wang, F.3    Dreyfuss, G.4
  • 29
    • 0021365589 scopus 로고
    • Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly
    • Madore, S. J., E. D. Wieben, and T. Pederson. 1984. Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J. Cell Biol. 98:188-192.
    • (1984) J. Cell Biol. , vol.98 , pp. 188-192
    • Madore, S.J.1    Wieben, E.D.2    Pederson, T.3
  • 30
    • 0023047717 scopus 로고
    • Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding
    • Mattaj, I. W. 1986. Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell 46:905-911.
    • (1986) Cell , vol.46 , pp. 905-911
    • Mattaj, I.W.1
  • 31
    • 0021926473 scopus 로고
    • Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins
    • Mattaj, I. W., and E. M. De Robertis. 1985. Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins. Cell 40:111-118.
    • (1985) Cell , vol.40 , pp. 111-118
    • Mattaj, I.W.1    De Robertis, E.M.2
  • 32
    • 0027993871 scopus 로고
    • The association of the U1-specific 70K and C proteins with U1 snRNPs is mediated in part by common U snRNP proteins
    • Nelissen, R. L., C. L. Will, W. J. van Venrooij, and R. Lührmann. 1994. The association of the U1-specific 70K and C proteins with U1 snRNPs is mediated in part by common U snRNP proteins. EMBO J. 13:4113-4125.
    • (1994) EMBO J. , vol.13 , pp. 4113-4125
    • Nelissen, R.L.1    Will, C.L.2    Van Venrooij, W.J.3    Lührmann, R.4
  • 33
    • 0025282484 scopus 로고
    • Nucleocytoplasmic transport and processing of small nuclear RNA precursors
    • Neuman de Vegvar, H. E., and J. E. Dahlberg. 1990. Nucleocytoplasmic transport and processing of small nuclear RNA precursors. Mol. Cell. Biol. 10:3365-3375.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 3365-3375
    • Neuman De Vegvar, H.E.1    Dahlberg, J.E.2
  • 34
    • 0028176685 scopus 로고
    • m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: Evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain
    • Plessel, G., U. Fischer, and R. Lührmann. 1994. m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: Evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain. Mol. Cell. Biol. 14:4160-4172.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4160-4172
    • Plessel, G.1    Fischer, U.2    Lührmann, R.3
  • 35
    • 0031575412 scopus 로고    scopus 로고
    • Electron microscopy of assembly intermediates of the snRNP core: Morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core
    • Plessel, G., R. Lührmann, and B. Kastner. 1997. Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core. J. Mol. Biol. 265:87-94.
    • (1997) J. Mol. Biol. , vol.265 , pp. 87-94
    • Plessel, G.1    Lührmann, R.2    Kastner, B.3
  • 36
    • 0030007060 scopus 로고    scopus 로고
    • The snRNP core assembly pathway: Identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro
    • Raker, V. A., G. Plessel, and R. Lührmann. 1996. The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro. EMBO J. 15:2256-2269.
    • (1996) EMBO J. , vol.15 , pp. 2256-2269
    • Raker, V.A.1    Plessel, G.2    Lührmann, R.3
  • 38
    • 0025159442 scopus 로고
    • Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts
    • Sauterer, R. A., A. Goyal, and G. W. Zieve. 1990. Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts. J. Biol. Chem. 265:1048-1058.
    • (1990) J. Biol. Chem. , vol.265 , pp. 1048-1058
    • Sauterer, R.A.1    Goyal, A.2    Zieve, G.W.3
  • 39
    • 0029124901 scopus 로고
    • In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs
    • Ségault, V., C. L. Will, B. S. Sproat, and R. Lührmann. 1995. In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs. EMBO J. 14:4010-4021.
    • (1995) EMBO J. , vol.14 , pp. 4010-4021
    • Ségault, V.1    Will, C.L.2    Sproat, B.S.3    Lührmann, R.4
  • 40
    • 0028997105 scopus 로고
    • Sm and Sm-like proteins belong to a large family: Identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs
    • Séraphin, B. 1995. Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs. EMBO J. 14:2089-2098.
    • (1995) EMBO J. , vol.14 , pp. 2089-2098
    • Séraphin, B.1
  • 41
    • 0026919628 scopus 로고
    • Vitro reconstitution of U1 and U2 snRNPs from isolated proteins and snRNA
    • Sumpter, V., A. Kahrs, U. Fischer, U. Kornstädt, and R. Lührmann. 1992. In vitro reconstitution of U1 and U2 snRNPs from isolated proteins and snRNA. Mol. Biol. Rep. 16:229-240.
    • (1992) Mol. Biol. Rep. , vol.16 , pp. 229-240
    • Sumpter, V.1    Kahrs, A.2    Fischer, U.3    Kornstädt, U.4    Lührmann, R.5
  • 42
    • 0024827307 scopus 로고
    • Cloned human snRNP proteins B and b′ differ only in their carboxyl-terminal part
    • Van Dam, A., I. Winkel, J. Zijlstra-Baalbergen, R. Smeenk, and H. T. Cuypers. 1989. Cloned human snRNP proteins B and B′ differ only in their carboxyl-terminal part. EMBO J. 8:3853-3860.
    • (1989) EMBO J. , vol.8 , pp. 3853-3860
    • Van Dam, A.1    Winkel, I.2    Zijlstra-Baalbergen, J.3    Smeenk, R.4    Cuypers, H.T.5
  • 43
    • 0343907206 scopus 로고    scopus 로고
    • Protein functions in pre-mRNA splicing
    • Will, C. L., and R. Lührmann. 1997. Protein functions in pre-mRNA splicing. Curr. Opin. Cell Biol. 9:320-328.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 320-328
    • Will, C.L.1    Lührmann, R.2
  • 44
    • 0026606665 scopus 로고
    • Nuclear processing of the 3′-terminal nucleotides of pre-U1 RNA in Xenopus laevis oocytes
    • Yang, H., M. L. Moss, E. Lund, and J. E. Dahlberg. 1992. Nuclear processing of the 3′-terminal nucleotides of pre-U1 RNA in Xenopus laevis oocytes. Mol. Cell. Biol. 12:1553-1560.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1553-1560
    • Yang, H.1    Moss, M.L.2    Lund, E.3    Dahlberg, J.E.4
  • 45
    • 0000996356 scopus 로고    scopus 로고
    • The growing world of small nuclear ribonucleoproteins
    • R. F. Gesteland, T. R. Cech, and J. F. Aktins (ed.), Cold Spring Harbor, New York
    • Yu, Y.-T., E. C. Scharl, C. M. Smith, and J. A. Steitz. 1999. The growing world of small nuclear ribonucleoproteins, p. 487-524. In R. F. Gesteland, T. R. Cech, and J. F. Aktins (ed.), The RNA World, 2nd ed. Cold Spring Harbor, New York.
    • (1999) The RNA World, 2nd Ed. , pp. 487-524
    • Yu, Y.-T.1    Scharl, E.C.2    Smith, C.M.3    Steitz, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.