WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

EMBO Journal

Volumn 18, Issue 14, 1999, Pages 3990-4003

  Mayo, Marty W ^a   Wang, Cun Yu ^b   Drouin, S Scott ^a   Madrid, Lee V ^a   Marshall, Allen F ^a   Reed, John C ^d   Weissman, Bernard E ^a,c   Baldwin, Albert S ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d BURNHAM INSTITUTE   (United States)

Author keywords

Apoptosis; Bcl 2; Transcriptional regulation; Wilms' tumor; WT1

Indexed keywords

DOXORUBICIN; PROTEIN BCL 2; STAUROSPORINE; VINCRISTINE; ZINC FINGER PROTEIN;

APOPTOSIS; ARTICLE; CANCER GENETICS; CELL KILLING; CELL SURVIVAL; CONTROLLED STUDY; DRUG RESISTANCE; GENE ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NEPHROBLASTOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTO ONCOGENE; RECEPTOR GENE; TRANSCRIPTION REGULATION; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; CONSENSUS SEQUENCE; DNA; DNA-BINDING PROTEINS; DOXORUBICIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; HUMANS; KIDNEY NEOPLASMS; MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; STAUROSPORINE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; VINCRISTINE; WILMS TUMOR; WT1 PROTEINS;

EID: 0033565656     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.14.3990     Document Type: Article

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