Neuronal apoptosis inhibitory protein expression after traumatic brain injury in the mouse

Journal of Neurotrauma

Volumn 18, Issue 12, 2001, Pages 1333-1347

  Hutchison, James S ^a,c   Robertson, George S ^a,c   MacKenzie, Alex E ^a,b,c   Derrane, Rachel E ^a,b,c   Johnston, Donna L ^a,b,c   Gendron, Nathalie ^a,b,c   Barnes, David ^a,b,c   Fliss, Henry ^a,b,c   King, William J ^a,b,c   Rasquinha, Ingrid ^a,b,c   MacManus, John ^a,b,c  

^a UNIVERSITY OF OTTAWA   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Apoptosis; Caspase; Immunofluorescence; Microglia; Neuronal apoptosis inhibitor protein (NAIP); Tumor necrosis factor alpha (TNF ); Western blot

Indexed keywords

BISBENZIMIDE; CASPASE INHIBITOR; CD11B ANTIGEN; CELL PROTEIN; DNA FRAGMENT; ENZYME PRECURSOR; MYELIN ASSOCIATED GLYCOPROTEIN; NEURONAL APOPTOSIS INHIBITORY PROTEIN; NUCLEAR PROTEIN; PROCASPASE 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; CELL ACTIVATION; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME MECHANISM; GEL ELECTROPHORESIS; IMMUNOFLUORESCENCE TEST; MALE; MICROGLIA; MOUSE; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; WESTERN BLOTTING; WHITE MATTER;

ANIMALS; APOPTOSIS; BRAIN INJURIES; CASPASE 3; CASPASES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENZYME PRECURSORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; NEURONS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035673909     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/08977150152725632     Document Type: Article

References (50)

1. The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F)
2. In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states
3. Expression of Fas and Fas ligand after experimental traumatic brain injury in the rat
4. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
5. Apoptosis-suppressor gene bcl-2 expression after traumatic brain injury in rats
6. Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury
7. Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury
8. Caspase-3 mediated neuronal death after traumatic brain injury in rats
9. Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
10. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
11. The neuronal apoptosis inhibitory protein (NAIP) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila
12. Sustained sensory/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouse
13. betaby human cerebral microvascular endothelium after percussive trauma
14. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
15. High-dose glucocorticoid treatment improves neurological recovery in head-injured mice
16. Effects of the 21-aminosteroid U74006F on experimental head injury in mice
17. DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat
18. The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury
19. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
20. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
21. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury
22. Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment
23. Complexity analysis of oligodendroglial processes expressing myelin-associated glycoprotein
24. The inhibitors of apoptosis (IAPs) and their emerging role in cancer
25. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
26. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
27. Protective effects of propranolol on experimentally head-injured mouse brains
28. Neuronal and glial apoptosis after traumatic spinal cord injury
29. Cerebral ischemia produces laddered DNA fragments distinct from cardiac ischemia and archtypal apoptosis
30. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain
31. DNA damage consistent with apoptosis in transient focal ischaemic neocortex
32. Differences in DNA fragmentation following transient cerebral or decapitation ischemia in rats
33. NAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathways
34. NeuN, a neuronal specific nuclear protein in vertebrates
35. Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons in vivo: A single-cell analysis
36. Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant
37. IAP family proteins delay motoneuron cell death in vivo
38. DNA fragmentation and nuclear endonuclease activity in rat brain after severe closed head injury
39. BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice
40. Apoptosis after traumatic brain injury
41. Evidence of apoptotic cell death after experimental traumatic brain injury in the rat
42. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury
43. Detection of poly(ADP-ribose) polymerase and its apoptosis-specific fragment by a nonisotopic activity-Western blot technique
44. Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant
45. Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury
46. Toxicity of TNF alpha and platelet activating factor for human NT2N neurons: A tissue culture model for human immunodeficiency virus dementia
47. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
48. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
49. Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein)
50. Insulin-like growth factor I protects oligodendrocytes from tumor necrosis factor-alpha-induced injury