Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy

Human Gene Therapy

Volumn 22, Issue 2, 2011, Pages 135-144

  Shababi, Monir ^a   Glascock, Jacqueline ^b   Lorson, Christian L ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; SOMATOMEDIN C; SURVIVAL MOTOR NEURON PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTISENSE VECTOR; ARTICLE; BODY MASS; DISEASE SEVERITY; GENE INDUCTION; LIFESPAN; MOUSE; NEUROPROTECTION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; RNA VECTOR; SPINAL MUSCULAR ATROPHY; TRANS SPLICING;

ANIMALS; DISEASE MODELS, ANIMAL; EXONS; GENE DUPLICATION; GENE THERAPY; GENETIC VECTORS; INFUSIONS, INTRAVENTRICULAR; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCULAR ATROPHY, SPINAL; PLASMIDS; RIBONUCLEOPROTEINS, SMALL NUCLEAR; SURVIVAL OF MOTOR NEURON 2 PROTEIN; TRANS-SPLICING;

ANIMALIA; MUS;

EID: 79951826869     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2010.114     Document Type: Article

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