Abolishing Bax-Dependent Apoptosis Shows Beneficial Effects on Spinal Muscular Atrophy Model Mice

Molecular Therapy

Volumn 13, Issue 6, 2006, Pages 1149-1155

  Tsai, Ming S ^a   Chiu, Yung T ^b   Wang, Sue H ^c   Hsieh Li, Hsiu M ^d   Lian, Wei C ^e   Li, Hung ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

^e CENTER FOR DISEASE CONTROL   (Taiwan)

Author keywords

Bax dependent apoptosis; motoneuron degeneration; motoneuron diseases; spinal muscular atrophy model mice

Indexed keywords

PROTEIN BAX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DISEASE SEVERITY; IN VIVO STUDY; KNOCKOUT MOUSE; LIFESPAN; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PATHOGENESIS; PROGENY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPINAL CORD MOTONEURON; SPINAL MUSCULAR ATROPHY; WILD TYPE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; DISEASE MODELS, ANIMAL; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; NERVE DEGENERATION; SPINAL CORD;

ANIMALIA;

EID: 33646881769     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2006.02.008     Document Type: Article

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