메뉴 건너뛰기




Volumn 15, Issue 1, 2014, Pages 39-53

A role for XLF in DNA repair and recombination in human somatic cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURVIVAL; DNA END-JOINING REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; GENOME, HUMAN; HCT116 CELLS; HOMOLOGOUS RECOMBINATION; HUMANS; PROTEIN TRANSPORT; V(D)J RECOMBINATION;

EID: 84894246166     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.12.006     Document Type: Article
Times cited : (19)

References (86)
  • 1
    • 39449085063 scopus 로고    scopus 로고
    • DNA-damage repair; the good, the bad, and the ugly
    • Hakem R. DNA-damage repair; the good, the bad, and the ugly. EMBO J. 2008, 27:589-605.
    • (2008) EMBO J. , vol.27 , pp. 589-605
    • Hakem, R.1
  • 2
    • 84867386682 scopus 로고    scopus 로고
    • Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks
    • Boboila C., Alt F.W., Schwer B. Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks. Adv. Immunol. 2012, 116:1-49.
    • (2012) Adv. Immunol. , vol.116 , pp. 1-49
    • Boboila, C.1    Alt, F.W.2    Schwer, B.3
  • 3
    • 70350088548 scopus 로고    scopus 로고
    • Mechanisms of double-strand break repair in somatic mammalian cells
    • Hartlerode A.J., Scully R. Mechanisms of double-strand break repair in somatic mammalian cells. Biochem. J. 2009, 423:157-168.
    • (2009) Biochem. J. , vol.423 , pp. 157-168
    • Hartlerode, A.J.1    Scully, R.2
  • 4
    • 77955841149 scopus 로고    scopus 로고
    • Collaboration and competition between DNA double-strand break repair pathways
    • Kass E.M., Jasin M. Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett. 2010, 584:3703-3708.
    • (2010) FEBS Lett. , vol.584 , pp. 3703-3708
    • Kass, E.M.1    Jasin, M.2
  • 5
    • 0000391880 scopus 로고    scopus 로고
    • Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle
    • Lee S.E., Mitchell R.A., Cheng A., Hendrickson E.A. Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle. Mol. Cell. Biol. 1997, 17:1425-1433.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1425-1433
    • Lee, S.E.1    Mitchell, R.A.2    Cheng, A.3    Hendrickson, E.A.4
  • 6
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • Rothkamm K., Kruger I., Thompson L.H., Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol. Cell. Biol. 2003, 23:5706-5715.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Kruger, I.2    Thompson, L.H.3    Lobrich, M.4
  • 7
    • 78649446475 scopus 로고    scopus 로고
    • A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
    • Dobbs T.A., Tainer J.A., Lees-Miller S.P. A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. DNA Repair (Amst) 2010, 9:1307-1314.
    • (2010) DNA Repair (Amst) , vol.9 , pp. 1307-1314
    • Dobbs, T.A.1    Tainer, J.A.2    Lees-Miller, S.P.3
  • 8
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
    • Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 9
    • 35348821296 scopus 로고    scopus 로고
    • A backup DNA repair pathway moves to the forefront
    • Nussenzweig A., Nussenzweig M.C. A backup DNA repair pathway moves to the forefront. Cell 2007, 131:223-225.
    • (2007) Cell , vol.131 , pp. 223-225
    • Nussenzweig, A.1    Nussenzweig, M.C.2
  • 10
    • 79956215808 scopus 로고    scopus 로고
    • Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways
    • Mladenov E., Iliakis G. Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways. Mutat. Res. 2011, 711:61-72.
    • (2011) Mutat. Res. , vol.711 , pp. 61-72
    • Mladenov, E.1    Iliakis, G.2
  • 12
    • 84868679968 scopus 로고    scopus 로고
    • DNA polymerases in nonhomologous end joining: are there any benefits to standing out from the crowd?
    • Ramsden D.A., Asagoshi K. DNA polymerases in nonhomologous end joining: are there any benefits to standing out from the crowd?. Environ. Mol. Mutagen. 2012, 53:741-751.
    • (2012) Environ. Mol. Mutagen. , vol.53 , pp. 741-751
    • Ramsden, D.A.1    Asagoshi, K.2
  • 13
    • 45749124305 scopus 로고    scopus 로고
    • Live cell imaging of XLF and XRCC4 reveals a novel view of protein assembly in the non-homologous end-joining pathway
    • Yano K., Chen D.J. Live cell imaging of XLF and XRCC4 reveals a novel view of protein assembly in the non-homologous end-joining pathway. Cell Cycle 2008, 7:1321-1325.
    • (2008) Cell Cycle , vol.7 , pp. 1321-1325
    • Yano, K.1    Chen, D.J.2
  • 14
    • 79952573454 scopus 로고    scopus 로고
    • Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF
    • Yano K., Morotomi-Yano K., Lee K.J., Chen D.J. Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF. FEBS Lett. 2011, 585:841-846.
    • (2011) FEBS Lett. , vol.585 , pp. 841-846
    • Yano, K.1    Morotomi-Yano, K.2    Lee, K.J.3    Chen, D.J.4
  • 15
    • 84870587195 scopus 로고    scopus 로고
    • The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage
    • Reynolds P., Anderson J.A., Harper J.V., Hill M.A., Botchway S.W., Parker A.W., O'Neill P. The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage. Nucleic Acids Res. 2012, 40:10821-10831.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10821-10831
    • Reynolds, P.1    Anderson, J.A.2    Harper, J.V.3    Hill, M.A.4    Botchway, S.W.5    Parker, A.W.6    O'Neill, P.7
  • 17
    • 0037155703 scopus 로고    scopus 로고
    • Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
    • Ma Y., Pannicke U., Schwarz K., Lieber M.R. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 2002, 108:781-794.
    • (2002) Cell , vol.108 , pp. 781-794
    • Ma, Y.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 19
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair
    • Teo S.H., Jackson S.P. Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J. 1997, 16:4788-4795.
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.H.1    Jackson, S.P.2
  • 20
    • 0030811523 scopus 로고    scopus 로고
    • Yeast DNA ligase IV mediates non-homologous DNA end joining
    • Wilson T.E., Grawunder U., Lieber M.R. Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature 1997, 388:495-498.
    • (1997) Nature , vol.388 , pp. 495-498
    • Wilson, T.E.1    Grawunder, U.2    Lieber, M.R.3
  • 21
    • 0032185230 scopus 로고    scopus 로고
    • DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes
    • Grawunder U., Zimmer D., Fugmann S., Schwarz K., Lieber M.R. DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol. Cell 1998, 2:477-484.
    • (1998) Mol. Cell , vol.2 , pp. 477-484
    • Grawunder, U.1    Zimmer, D.2    Fugmann, S.3    Schwarz, K.4    Lieber, M.R.5
  • 25
    • 84859394323 scopus 로고    scopus 로고
    • The response to and repair of RAG-mediated DNA double-strand breaks
    • Helmink B.A., Sleckman B.P. The response to and repair of RAG-mediated DNA double-strand breaks. Annu. Rev. Immunol. 2012, 30:175-202.
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 175-202
    • Helmink, B.A.1    Sleckman, B.P.2
  • 26
    • 84867847788 scopus 로고    scopus 로고
    • Role of non-homologous end joining in V(D)J recombination
    • Malu S., Malshetty V., Francis D., Cortes P. Role of non-homologous end joining in V(D)J recombination. Immunol. Res. 2012, 54:233-246.
    • (2012) Immunol. Res. , vol.54 , pp. 233-246
    • Malu, S.1    Malshetty, V.2    Francis, D.3    Cortes, P.4
  • 28
    • 60349111074 scopus 로고    scopus 로고
    • Cernunnos/XLF: a new player in DNA double-strand break repair
    • Yano K., Morotomi-Yano K., Akiyama H. Cernunnos/XLF: a new player in DNA double-strand break repair. Int J Biochem Cell Biol 2009, 41:1237-1240.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1237-1240
    • Yano, K.1    Morotomi-Yano, K.2    Akiyama, H.3
  • 30
    • 84863268623 scopus 로고    scopus 로고
    • Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development
    • Liu X., Jiang W., Dubois R.L., Yamamoto K., Wolner Z., Zha S. Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:3903-3908.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 3903-3908
    • Liu, X.1    Jiang, W.2    Dubois, R.L.3    Yamamoto, K.4    Wolner, Z.5    Zha, S.6
  • 32
    • 84873427676 scopus 로고    scopus 로고
    • Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining
    • Oksenych V., Kumar V., Liu X., Guo C., Schwer B., Zha S., Alt F.W. Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:2234-2239.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 2234-2239
    • Oksenych, V.1    Kumar, V.2    Liu, X.3    Guo, C.4    Schwer, B.5    Zha, S.6    Alt, F.W.7
  • 34
    • 31044432090 scopus 로고    scopus 로고
    • XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
    • Ahnesorg P., Smith P., Jackson S.P. XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell 2006, 124:301-313.
    • (2006) Cell , vol.124 , pp. 301-313
    • Ahnesorg, P.1    Smith, P.2    Jackson, S.P.3
  • 36
    • 33744938713 scopus 로고    scopus 로고
    • Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1
    • Callebaut I., Malivert L., Fischer A., Mornon J.P., Revy P., de Villartay J.P. Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1. J. Biol. Chem. 2006, 281:13857-13860.
    • (2006) J. Biol. Chem. , vol.281 , pp. 13857-13860
    • Callebaut, I.1    Malivert, L.2    Fischer, A.3    Mornon, J.P.4    Revy, P.5    de Villartay, J.P.6
  • 38
    • 37349113779 scopus 로고    scopus 로고
    • Crystal structure of human XLF: a twist in nonhomologous DNA end-joining
    • Andres S.N., Modesti M., Tsai C.J., Chu G., Junop M.S. Crystal structure of human XLF: a twist in nonhomologous DNA end-joining. Mol. Cell 2007, 28:1093-1101.
    • (2007) Mol. Cell , vol.28 , pp. 1093-1101
    • Andres, S.N.1    Modesti, M.2    Tsai, C.J.3    Chu, G.4    Junop, M.S.5
  • 40
    • 34548567192 scopus 로고    scopus 로고
    • Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4
    • Deshpande R.A., Wilson T.E. Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) 2007, 6:1507-1516.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 1507-1516
    • Deshpande, R.A.1    Wilson, T.E.2
  • 41
    • 34249685474 scopus 로고    scopus 로고
    • Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity
    • Lu H., Pannicke U., Schwarz K., Lieber M.R. Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity. J. Biol. Chem. 2007, 282:11155-11162.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11155-11162
    • Lu, H.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 45
    • 80053358977 scopus 로고    scopus 로고
    • Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions
    • (suppl. 1382 p following 1392)
    • Wu Q., Ochi T., Matak-Vinkovic D., Robinson C.V., Chirgadze D.Y., Blundell T.L. Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions. Biochem. Soc. Trans. 2011, 39:1387-1392. (suppl. 1382 p following 1392).
    • (2011) Biochem. Soc. Trans. , vol.39 , pp. 1387-1392
    • Wu, Q.1    Ochi, T.2    Matak-Vinkovic, D.3    Robinson, C.V.4    Chirgadze, D.Y.5    Blundell, T.L.6
  • 46
    • 31044446441 scopus 로고    scopus 로고
    • DNA double-strand break repair: a relentless hunt uncovers new prey
    • Sekiguchi J.M., Ferguson D.O. DNA double-strand break repair: a relentless hunt uncovers new prey. Cell 2006, 124:260-262.
    • (2006) Cell , vol.124 , pp. 260-262
    • Sekiguchi, J.M.1    Ferguson, D.O.2
  • 47
    • 34848841930 scopus 로고    scopus 로고
    • Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence
    • Gu J., Lu H., Tsai A.G., Schwarz K., Lieber M.R. Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence. Nucleic Acids Res. 2007, 35:5755-5762.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 5755-5762
    • Gu, J.1    Lu, H.2    Tsai, A.G.3    Schwarz, K.4    Lieber, M.R.5
  • 48
    • 34249938518 scopus 로고    scopus 로고
    • Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends
    • Tsai C.J., Kim S.A., Chu G. Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:7851-7856.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 7851-7856
    • Tsai, C.J.1    Kim, S.A.2    Chu, G.3
  • 50
    • 52049117396 scopus 로고    scopus 로고
    • DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks
    • Yu Y., Mahaney B.L., Yano K., Ye R., Fang S., Douglas P., Chen D.J., Lees-Miller S.P. DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks. DNA Repair (Amst) 2008, 7:1680-1692.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1680-1692
    • Yu, Y.1    Mahaney, B.L.2    Yano, K.3    Ye, R.4    Fang, S.5    Douglas, P.6    Chen, D.J.7    Lees-Miller, S.P.8
  • 51
    • 34248400443 scopus 로고    scopus 로고
    • Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
    • Zha S., Alt F.W., Cheng H.L., Brush J.W., Li G. Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:4518-4523.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 4518-4523
    • Zha, S.1    Alt, F.W.2    Cheng, H.L.3    Brush, J.W.4    Li, G.5
  • 52
    • 77649225150 scopus 로고    scopus 로고
    • Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells
    • Fattah F., Lee E.H., Weisensel N., Wang Y., Lichter N., Hendrickson E.A. Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells. PLoS Genet. 2010, 6:e1000855.
    • (2010) PLoS Genet. , vol.6
    • Fattah, F.1    Lee, E.H.2    Weisensel, N.3    Wang, Y.4    Lichter, N.5    Hendrickson, E.A.6
  • 53
    • 17444434208 scopus 로고    scopus 로고
    • Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses
    • Kohli M., Rago C., Lengauer C., Kinzler K.W., Vogelstein B. Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Nucleic Acids Res. 2004, 32:e3.
    • (2004) Nucleic Acids Res. , vol.32
    • Kohli, M.1    Rago, C.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 54
    • 70350717187 scopus 로고    scopus 로고
    • Functional dissection of mitotic regulators through gene targeting in human somatic cells
    • Berdougo E., Terret M.E., Jallepalli P.V. Functional dissection of mitotic regulators through gene targeting in human somatic cells. Methods Mol. Biol. 2009, 545:21-37.
    • (2009) Methods Mol. Biol. , vol.545 , pp. 21-37
    • Berdougo, E.1    Terret, M.E.2    Jallepalli, P.V.3
  • 55
    • 79960046970 scopus 로고    scopus 로고
    • AAV-mediated gene targeting methods for human cells
    • Khan I.F., Hirata R.K., Russell D.W. AAV-mediated gene targeting methods for human cells. Nat. Protoc. 2011, 6:482-501.
    • (2011) Nat. Protoc. , vol.6 , pp. 482-501
    • Khan, I.F.1    Hirata, R.K.2    Russell, D.W.3
  • 56
    • 0024052153 scopus 로고
    • The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement
    • Hendrickson E.A., Schatz D.G., Weaver D.T. The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement. Genes Dev. 1988, 2:817-829.
    • (1988) Genes Dev. , vol.2 , pp. 817-829
    • Hendrickson, E.A.1    Schatz, D.G.2    Weaver, D.T.3
  • 60
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce A.J., Johnson R.D., Thompson L.H., Jasin M. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev. 1999, 13:2633-2638.
    • (1999) Genes Dev. , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3    Jasin, M.4
  • 61
    • 6344234817 scopus 로고    scopus 로고
    • Genetic steps of mammalian homologous repair with distinct mutagenic consequences
    • Stark J.M., Pierce A.J., Oh J., Pastink A., Jasin M. Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol. Cell. Biol. 2004, 24:9305-9316.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9305-9316
    • Stark, J.M.1    Pierce, A.J.2    Oh, J.3    Pastink, A.4    Jasin, M.5
  • 62
    • 46249131123 scopus 로고    scopus 로고
    • Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
    • Bennardo N., Cheng A., Huang N., Stark J.M. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet. 2008, 4:e1000110.
    • (2008) PLoS Genet. , vol.4
    • Bennardo, N.1    Cheng, A.2    Huang, N.3    Stark, J.M.4
  • 64
    • 0031974686 scopus 로고    scopus 로고
    • V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability
    • Gauss G.H., Domain I., Hsieh C.L., Lieber M.R. V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability. Eur. J. Immunol. 1998, 28:351-358.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 351-358
    • Gauss, G.H.1    Domain, I.2    Hsieh, C.L.3    Lieber, M.R.4
  • 65
    • 0026687789 scopus 로고
    • The basis for the mechanistic bias for deletional over inversional V(D)J recombination
    • Gauss G.H., Lieber M.R. The basis for the mechanistic bias for deletional over inversional V(D)J recombination. Genes Dev. 1992, 6:1553-1561.
    • (1992) Genes Dev. , vol.6 , pp. 1553-1561
    • Gauss, G.H.1    Lieber, M.R.2
  • 66
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger M.A., Schatz D.G., Gorka C., Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 1990, 248:1517-1523.
    • (1990) Science , vol.248 , pp. 1517-1523
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 68
    • 47249150446 scopus 로고    scopus 로고
    • Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells
    • Fattah F.J., Lichter N.F., Fattah K.R., Oh S., Hendrickson E.A. Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:8703-8708.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 8703-8708
    • Fattah, F.J.1    Lichter, N.F.2    Fattah, K.R.3    Oh, S.4    Hendrickson, E.A.5
  • 69
    • 53549118024 scopus 로고    scopus 로고
    • The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells
    • Ruis B.L., Fattah K.R., Hendrickson E.A. The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells. Mol. Cell. Biol. 2008, 28:6182-6195.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 6182-6195
    • Ruis, B.L.1    Fattah, K.R.2    Hendrickson, E.A.3
  • 70
    • 34248356003 scopus 로고    scopus 로고
    • Cellular response to etoposide treatment
    • Montecucco A., Biamonti G. Cellular response to etoposide treatment. Cancer Lett. 2007, 252:9-18.
    • (2007) Cancer Lett. , vol.252 , pp. 9-18
    • Montecucco, A.1    Biamonti, G.2
  • 72
    • 0042830859 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: taking an inventory
    • Fried H., Kutay U. Nucleocytoplasmic transport: taking an inventory. Cell. Mol. Life Sci. 2003, 60:1659-1688.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 1659-1688
    • Fried, H.1    Kutay, U.2
  • 75
    • 68749100947 scopus 로고    scopus 로고
    • Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair
    • Zhang Y., Rohde L.H., Wu H. Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair. Curr. Genomics 2009, 10:250-258.
    • (2009) Curr. Genomics , vol.10 , pp. 250-258
    • Zhang, Y.1    Rohde, L.H.2    Wu, H.3
  • 76
    • 68249150701 scopus 로고    scopus 로고
    • Mre11: roles in DNA repair beyond homologous recombination
    • Zha S., Boboila C., Alt F.W. Mre11: roles in DNA repair beyond homologous recombination. Nat. Struct. Mol. Biol. 2009, 16:798-800.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 798-800
    • Zha, S.1    Boboila, C.2    Alt, F.W.3
  • 78
    • 42249085637 scopus 로고    scopus 로고
    • Gene targeting in human somatic cells
    • Humana Press, Inc., Totowa, NJ, P.M. Conn (Ed.)
    • Hendrickson E.A. Gene targeting in human somatic cells. Source Book of Models for Biomedical Research 2008, 509-525. Humana Press, Inc., Totowa, NJ. P.M. Conn (Ed.).
    • (2008) Source Book of Models for Biomedical Research , pp. 509-525
    • Hendrickson, E.A.1
  • 80
    • 68149110347 scopus 로고    scopus 로고
    • Ku86 represses lethal telomere deletion events in human somatic cells
    • Wang Y., Ghosh G., Hendrickson E.A. Ku86 represses lethal telomere deletion events in human somatic cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:12430-12435.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 12430-12435
    • Wang, Y.1    Ghosh, G.2    Hendrickson, E.A.3
  • 81
    • 84873639894 scopus 로고    scopus 로고
    • Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction
    • Oh S., Wang Y., Zimbric J., Hendrickson E.A. Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction. Nucleic Acids Res. 2013, 41:1734-1749.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 1734-1749
    • Oh, S.1    Wang, Y.2    Zimbric, J.3    Hendrickson, E.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.