Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction

Nucleic Acids Research

Volumn 41, Issue 3, 2013, Pages 1734-1749

  Oh, Sehyun ^a   Wang, Yongbao ^a   Zimbric, Jacob ^a   Hendrickson, Eric A ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; COMPLEMENTARY DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAD54 PROTEIN; TELOMERE RECOGNITION FACTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA LIGASE IV GENE; EPITHELIUM CELL; GENE FUNCTION; GENE FUSION; GENE INACTIVATION; GENE LOSS; GENE TARGETING; GENOMIC INSTABILITY; HOMEOSTASIS; HUMAN; HUMAN CELL; LOSS OF FUNCTION MUTATION; MOLECULAR CLONING; NULL ALLELE; PRIORITY JOURNAL; RAD54B GENE; SISTER CHROMATID; SOMATIC CELL; TELOMERE;

ANTIGENS, NUCLEAR; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIDS; CHROMOSOME ABERRATIONS; DNA DAMAGE; DNA END-JOINING REPAIR; DNA HELICASES; DNA LIGASES; DNA-BINDING PROTEINS; GENE TARGETING; GENOMIC INSTABILITY; HUMANS; MUTATION; NUCLEAR PROTEINS; RECOMBINATION, GENETIC; RECOMBINATIONAL DNA REPAIR; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERIC REPEAT BINDING PROTEIN 2;

EID: 84873639894     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks1326     Document Type: Article

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