Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

EMBO Journal

Volumn 27, Issue 1, 2008, Pages 290-300

  Li, Yi ^a   Chirgadze, Dimitri Y ^a   Bolanos Garcia, Victor M ^a   Sibanda, Bancinyane L ^a   Davies, Owen R ^a   Ahnesorg, Peter ^a,b   Jackson, Stephen P ^a,b   Blundell, Tom L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Coiled coil; Homodimer; Non homologous end joining (NHEJ); Structure; XRCC4

Indexed keywords

AMINO ACID; DIMER; ENDONUCLEASE; HETERODIMER; HOMODIMER; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN CERNUNNOS; PROTEIN XLF; PROTEIN XRCC4; UNCLASSIFIED DRUG;

ARTICLE; BIOPHYSICS; CARBOXY TERMINAL SEQUENCE; CONSERVATION BIOLOGY; CRYSTAL STRUCTURE; DNA REPAIR; DNA STRAND BREAKAGE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; IMMUNE DEFICIENCY; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; STRUCTURAL HOMOLOGY; SURFACE PLASMON RESONANCE; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; HUMANS; MICE; MOLECULAR SEQUENCE DATA; RATS; SURFACE PROPERTIES; XENOPUS PROTEINS; ZEBRAFISH PROTEINS;

EID: 38049034405     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601942     Document Type: Article

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