Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

PLoS Genetics

Volumn 6, Issue 2, 2010, Pages

  Fattaha, Farjana ^a,b   Lee, Eu Han ^a   Weisenselb, Natalie ^a,c   Wang, Yongbao ^a   Lichter, Natalie ^a   Hendrickson, Eric A ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DNA DEPENDENT PROTEIN KINASE; KU ANTIGEN; NUCLEIC ACID BINDING PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE 4; PROTEIN SUBUNIT; PROTEIN XLF; UNCLASSIFIED DRUG; DNA; DNA BINDING PROTEIN; HELICASE; NHEJ1 PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE (ATP); PRKDC PROTEIN, HUMAN; XRCC5 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION; GENETIC ENGINEERING; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN FUNCTION; RODENT; SIGNAL TRANSDUCTION; SOMATIC CELL; ANIMAL; CELL STRAIN HCT116; GENETIC RECOMBINATION; GENETICS; HAMSTER; HAPLOIDY; METABOLISM; MUTATION; PLASMID; REPRODUCIBILITY;

ADENO-ASSOCIATED VIRUS; MAMMALIA;

ANIMALS; CRICETINAE; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA HELICASES; DNA LIGASES; DNA REPAIR; DNA REPAIR ENZYMES; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HAPLOIDY; HCT116 CELLS; HUMANS; MUTATION; NUCLEAR PROTEINS; PLASMIDS; RECOMBINATION, GENETIC; REPRODUCIBILITY OF RESULTS;

EID: 77649225150     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000855     Document Type: Article

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