A crosstalk between p21 and UPR-induced transcription factor C/EBP homologous protein (CHOP) linked to type 2 diabetes

Biochimie

Volumn 99, Issue 1, 2014, Pages 19-27

  Mihailidou, Chrysovalantou ^a   Papavassiliou, Athanasios G ^a   Kiaris, Hippokratis ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Apoptosis; CHOP; Diabetes; ER stress; p21; UPR

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYCLIN DEPENDENT KINASE; GLUCOSE; INITIATION FACTOR 2ALPHA; INSULIN; PROTEIN P21; STREPTOZOCIN;

ADIPOSE TISSUE; APOPTOSIS; BIOACCUMULATION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL PROTECTION; CELL REGENERATION; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FACILITATION; GENE DELETION; GENE MUTATION; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; LIPID DIET; LIVER ISCHEMIA; MUSCLE ISCHEMIA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; PROTEIN QUALITY; REPERFUSION INJURY; REVIEW; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SURVIVAL; TARGET ORGAN; UNFOLDED PROTEIN RESPONSE; WOLFRAM SYNDROME;

APOPTOSIS; CHOP; DIABETES; ER-STRESS; P21; UPR;

ANIMALS; APOPTOSIS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; HUMANS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; LIVER; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE;

EID: 84894043154     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2013.11.003     Document Type: Review

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