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Volumn 65, Issue 10, 2005, Pages 3980-3985

Lost in transcription: p21 repression, mechanisms, and consequences

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA METHYLTRANSFERASE; HELIX LOOP HELIX PROTEIN; MYC PROTEIN; PHOSPHOLIPASE D1; PHOSPHOLIPASE D2; POLO LIKE KINASE 1; PROTEIN P15; PROTEIN P27; PROTEIN P53; PROTEIN P75; SMALL INTERFERING RNA; T BOX TRANSCRIPTION FACTOR; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MIZ1; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TRANSCRIPTION FACTOR TBX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 20144384882     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-3995     Document Type: Review
Times cited : (735)

References (78)
  • 3
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
    • Waga S, Hannon GJ, Beach D, Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994;369:574-8.
    • (1994) Nature , vol.369 , pp. 574-578
    • Waga, S.1    Hannon, G.J.2    Beach, D.3    Stillman, B.4
  • 4
    • 0030973878 scopus 로고    scopus 로고
    • New functional activities for the p21 family of CDK inhibitors
    • LaBaer J, Garrett MD, Stevenson LF, et al. New functional activities for the p21 family of CDK inhibitors. Genes Dev 1997;11:847-62.
    • (1997) Genes Dev , vol.11 , pp. 847-862
    • LaBaer, J.1    Garrett, M.D.2    Stevenson, L.F.3
  • 5
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 7
    • 0031961995 scopus 로고    scopus 로고
    • 2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • 2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol 1998;18: 629-43.
    • (1998) Mol Cell Biol , vol.18 , pp. 629-643
    • Niculescu III, A.B.1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5    Reed, S.I.6
  • 8
    • 0030743399 scopus 로고    scopus 로고
    • WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases
    • Ogryzko VV, Wong P, Howard BH. WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases. Mol Cell Biol 1997;17:4877-82.
    • (1997) Mol Cell Biol , vol.17 , pp. 4877-4882
    • Ogryzko, V.V.1    Wong, P.2    Howard, B.H.3
  • 9
    • 2942554804 scopus 로고    scopus 로고
    • Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle
    • Radhakrishnan SK, Feliciano CS, Najmabadi F, et al. Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle. Oncogene 2004;23:4173-6.
    • (2004) Oncogene , vol.23 , pp. 4173-4176
    • Radhakrishnan, S.K.1    Feliciano, C.S.2    Najmabadi, F.3
  • 12
    • 7944226274 scopus 로고    scopus 로고
    • A novel p21(WAF1/CIP1) transcript is highly dependent on p53 for its basal expression in mouse tissues
    • Gartel AL, Radhakrishnan SK, Serfas MS, Kwon YH, Tyner AL. A novel p21(WAF1/CIP1) transcript is highly dependent on p53 for its basal expression in mouse tissues. Oncogene 2004;23:8154-7.
    • (2004) Oncogene , vol.23 , pp. 8154-8157
    • Gartel, A.L.1    Radhakrishnan, S.K.2    Serfas, M.S.3    Kwon, Y.H.4    Tyner, A.L.5
  • 13
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21(WAF1/CIP1) gene
    • Gartel AL, Tyner AL. Transcriptional regulation of the p21(WAF1/CIP1) gene. Exp Cell Res 1999;246:280-9.
    • (1999) Exp Cell Res , vol.246 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 14
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 2002;1:639-49.
    • (2002) Mol Cancer Ther , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 18
    • 0037330625 scopus 로고    scopus 로고
    • Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes
    • Gartel AL, Shchors K. Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes. Exp Cell Res 2003;283:17-21.
    • (2003) Exp Cell Res , vol.283 , pp. 17-21
    • Gartel, A.L.1    Shchors, K.2
  • 19
    • 0034724389 scopus 로고    scopus 로고
    • Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
    • Coller HA, Grandori C, Tamayo P, et al. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci U S A 2000;97:3260-5.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3260-3265
    • Coller, H.A.1    Grandori, C.2    Tamayo, P.3
  • 20
    • 0034662959 scopus 로고    scopus 로고
    • A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest
    • Claassen GF, Hann SR. A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest. Proc Natl Acad Sci U S A 2000;97:9498-503.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9498-9503
    • Claassen, G.F.1    Hann, S.R.2
  • 21
    • 0035836706 scopus 로고    scopus 로고
    • Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3
    • Gartel AL, Ye X, Goufman E, et al. Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A 2001;98:4510-5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4510-4515
    • Gartel, A.L.1    Ye, X.2    Goufman, E.3
  • 22
    • 0032920581 scopus 로고    scopus 로고
    • Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells
    • Mitchell KO, El-Deiry WS. Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells. Cell Growth Differ 1999;10:223-30.
    • (1999) Cell Growth Differ , vol.10 , pp. 223-230
    • Mitchell, K.O.1    El-Deiry, W.S.2
  • 23
    • 0037126303 scopus 로고    scopus 로고
    • Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • Seoane J, Le HV, Massague J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002;419:729-34.
    • (2002) Nature , vol.419 , pp. 729-734
    • Seoane, J.1    Le, H.V.2    Massague, J.3
  • 24
    • 0037461931 scopus 로고    scopus 로고
    • Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter
    • Wu S, Cetinkaya C, Munoz-Alonso MJ, et al. Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. Oncogene 2003;22:351-60.
    • (2003) Oncogene , vol.22 , pp. 351-360
    • Wu, S.1    Cetinkaya, C.2    Munoz-Alonso, M.J.3
  • 25
    • 18644373146 scopus 로고    scopus 로고
    • The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • van de Wetering M, Sancho E, Verweij C, et al. The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002;111: 241-50.
    • (2002) Cell , vol.111 , pp. 241-250
    • Van De Wetering, M.1    Sancho, E.2    Verweij, C.3
  • 26
    • 0345743712 scopus 로고    scopus 로고
    • Myc-interacting protein 1 target gene profile: A link to microtubules, extracellular signal-regulated kinase, and cell growth
    • Ziegelbauer J, Wei J, Tjian R. Myc-interacting protein 1 target gene profile: a link to microtubules, extracellular signal-regulated kinase, and cell growth. Proc Natl Acad Sci U S A 2004;101:458-63.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 458-463
    • Ziegelbauer, J.1    Wei, J.2    Tjian, R.3
  • 27
    • 12544256261 scopus 로고    scopus 로고
    • Myc antagonizes ras-mediated growth arrest in leukemia cells through the inhibition of the ras-ERK-p21Cip1 pathway
    • Vaque JP, Navascues J, Shiio Y, et al. Myc Antagonizes Ras-mediated Growth Arrest in Leukemia Cells through the Inhibition of the Ras-ERK-p21Cip1 Pathway. J Biol Chem 2005;280:1112-22.
    • (2005) J Biol Chem , vol.280 , pp. 1112-1122
    • Vaque, J.P.1    Navascues, J.2    Shiio, Y.3
  • 28
    • 13444270415 scopus 로고    scopus 로고
    • Myc represses transcription through recruitment of DNA methyltransferase corepressor
    • Brenner C, Deplus R, Didelot C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J 2005;24:336-46.
    • (2005) EMBO J , vol.24 , pp. 336-346
    • Brenner, C.1    Deplus, R.2    Didelot, C.3
  • 29
    • 0037718341 scopus 로고    scopus 로고
    • Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression
    • Mao DY, Watson JD, Yan PS, et al. Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression. Curr Biol 2003;13:882-6.
    • (2003) Curr Biol , vol.13 , pp. 882-886
    • Mao, D.Y.1    Watson, J.D.2    Yan, P.S.3
  • 30
    • 0344009714 scopus 로고    scopus 로고
    • c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis
    • Arango D, Mariadason JM, Wilson AJ, et al. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. Br J Cancer 2003;89:1757-65.
    • (2003) Br J Cancer , vol.89 , pp. 1757-1765
    • Arango, D.1    Mariadason, J.M.2    Wilson, A.J.3
  • 31
    • 0035910420 scopus 로고    scopus 로고
    • Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway
    • Chang WT, Kang JJ, Lee KY, et al. Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway. J Biol Chem 2001;276:2221-7.
    • (2001) J Biol Chem , vol.276 , pp. 2221-2227
    • Chang, W.T.1    Kang, J.J.2    Lee, K.Y.3
  • 32
    • 11244325724 scopus 로고    scopus 로고
    • Inhibition of p53-mediated transcriptional responses by mithramycin A
    • Koutsodontis G, Kardassis D. Inhibition of p53-mediated transcriptional responses by mithramycin A. Oncogene 2004;23:9190-200.
    • (2004) Oncogene , vol.23 , pp. 9190-9200
    • Koutsodontis, G.1    Kardassis, D.2
  • 33
    • 0344629425 scopus 로고    scopus 로고
    • Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression
    • McConnell MJ, Chevallier N, Berkofsky-Fessler W, et al. Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression. Mol Cell Biol 2003;23:9375-88.
    • (2003) Mol Cell Biol , vol.23 , pp. 9375-9388
    • McConnell, M.J.1    Chevallier, N.2    Berkofsky-Fessler, W.3
  • 35
    • 0842277812 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
    • Gui CY, Ngo L, Xu WS, Richon VM, Marks PA. Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. Proc Natl Acad Sci U S A 2004;101:1241-6.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1241-1246
    • Gui, C.Y.1    Ngo, L.2    Xu, W.S.3    Richon, V.M.4    Marks, P.A.5
  • 36
    • 5144222440 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor, Trichostatin A, activates p21(WAF1/CIP1) expression through down-regulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells
    • Li H, Wu X. Histone deacetylase inhibitor, Trichostatin A, activates p21(WAF1/CIP1) expression through down-regulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. Biochem Biophys Res Commun 2004;324:860-7.
    • (2004) Biochem Biophys Res Commun , vol.324 , pp. 860-867
    • Li, H.1    Wu, X.2
  • 37
    • 0037377761 scopus 로고    scopus 로고
    • The ΔNp63α phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA. The ΔNp63α phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 2003;23: 2264-76.
    • (2003) Mol Cell Biol , vol.23 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 38
    • 2942623616 scopus 로고    scopus 로고
    • Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation
    • Ando K, Ozaki T, Yamamoto H, et al. Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation. J Biol Chem 2004;279:25549-61.
    • (2004) J Biol Chem , vol.279 , pp. 25549-25561
    • Ando, K.1    Ozaki, T.2    Yamamoto, H.3
  • 39
    • 0033564832 scopus 로고    scopus 로고
    • Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck
    • Knecht R, Elez R, Oechler M, Solbach C, von Ilberg C, Strebhardt K. Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck. Cancer Res 1999;59:2794-7.
    • (1999) Cancer Res , vol.59 , pp. 2794-2797
    • Knecht, R.1    Elez, R.2    Oechler, M.3    Solbach, C.4    Von Ilberg, C.5    Strebhardt, K.6
  • 40
    • 0038018608 scopus 로고    scopus 로고
    • Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2
    • Kwun HJ, Lee JH, Min do S, Jang KL. Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2. FEBS Lett 2003;544:38-44.
    • (2003) FEBS Lett , vol.544 , pp. 38-44
    • Kwun, H.J.1    Lee, J.H.2    Do Min, S.3    Jang, K.L.4
  • 41
    • 0033104956 scopus 로고    scopus 로고
    • Control of cell cycle progression by c-Jun is p53 dependent
    • Schreiber M, Kolbus A, Piu F, et al. Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev 1999;13:607-19.
    • (1999) Genes Dev , vol.13 , pp. 607-619
    • Schreiber, M.1    Kolbus, A.2    Piu, F.3
  • 42
    • 6344253201 scopus 로고    scopus 로고
    • Mechanisms of human papillomavirus-induced oncogenesis
    • Munger K, Baldwin A, Edwards KM, et al. Mechanisms of human papillomavirus-induced oncogenesis. J Virol 2004;78:11451-60.
    • (2004) J Virol , vol.78 , pp. 11451-11460
    • Munger, K.1    Baldwin, A.2    Edwards, K.M.3
  • 43
    • 4644276886 scopus 로고    scopus 로고
    • Activation of RB/E2F signaling pathway is required for the modulation of hepatitis C virus core protein-induced cell growth in liver and non-liver cells
    • Hassan M, Ghozlan H, Abdel-Kader O. Activation of RB/E2F signaling pathway is required for the modulation of hepatitis C virus core protein-induced cell growth in liver and non-liver cells. Cell Signal 2004;16:1375-85.
    • (2004) Cell Signal , vol.16 , pp. 1375-1385
    • Hassan, M.1    Ghozlan, H.2    Abdel-Kader, O.3
  • 44
    • 0035148645 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner
    • Majumder M, Ghosh AK, Steele R, Ray R, Ray RB. Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner. J Virol 2001;75:1401-7.
    • (2001) J Virol , vol.75 , pp. 1401-1407
    • Majumder, M.1    Ghosh, A.K.2    Steele, R.3    Ray, R.4    Ray, R.B.5
  • 45
    • 0034852454 scopus 로고    scopus 로고
    • p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3
    • Kwun HJ, Jung EY, Ahn JY, Lee MN, Jang KL. p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3. J Gen Virol 2001;82:2235-41.
    • (2001) J Gen Virol , vol.82 , pp. 2235-2241
    • Kwun, H.J.1    Jung, E.Y.2    Ahn, J.Y.3    Lee, M.N.4    Jang, K.L.5
  • 47
    • 0032832571 scopus 로고    scopus 로고
    • c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1
    • Kardassis D, Papakosta P, Pardali K, Moustakas A. c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1. J Biol Chem 1999;274:29572-81.
    • (1999) J Biol Chem , vol.274 , pp. 29572-29581
    • Kardassis, D.1    Papakosta, P.2    Pardali, K.3    Moustakas, A.4
  • 48
    • 0035812298 scopus 로고    scopus 로고
    • Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway
    • Ahn JY, Chung EY, Kwun HJ, Jang KL. Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway. Gene 2001;275:163-8.
    • (2001) Gene , vol.275 , pp. 163-168
    • Ahn, J.Y.1    Chung, E.Y.2    Kwun, H.J.3    Jang, K.L.4
  • 49
    • 0037383786 scopus 로고    scopus 로고
    • The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene
    • Lagger G, Doetzlhofer A, Schuettengruber B, et al. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol Cell Biol 2003;23:2669-79.
    • (2003) Mol Cell Biol , vol.23 , pp. 2669-2679
    • Lagger, G.1    Doetzlhofer, A.2    Schuettengruber, B.3
  • 50
    • 0037042205 scopus 로고    scopus 로고
    • Cooperative repression of cyclin-dependent kinase inhibitor p21 gene expression by hepatitis B virus X protein and hepatitis C virus core protein
    • Han HJ, Jung EY, Lee WJ, Jang KL. Cooperative repression of cyclin-dependent kinase inhibitor p21 gene expression by hepatitis B virus X protein and hepatitis C virus core protein. FEBS Lett 2002;518:169-72.
    • (2002) FEBS Lett , vol.518 , pp. 169-172
    • Han, H.J.1    Jung, E.Y.2    Lee, W.J.3    Jang, K.L.4
  • 51
    • 0030879868 scopus 로고    scopus 로고
    • Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins
    • Prabhu S, Ignatova A, Park ST, Sun XH. Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins. Mol Cell Biol 1997;17:5888-96.
    • (1997) Mol Cell Biol , vol.17 , pp. 5888-5896
    • Prabhu, S.1    Ignatova, A.2    Park, S.T.3    Sun, X.H.4
  • 52
    • 12144286826 scopus 로고    scopus 로고
    • Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD
    • Kim JY, Chu K, Kim HJ, et al. Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD. Mol Endocrinol 2004;18:776-90.
    • (2004) Mol Endocrinol , vol.18 , pp. 776-790
    • Kim, J.Y.1    Chu, K.2    Kim, H.J.3
  • 53
    • 5644261273 scopus 로고    scopus 로고
    • ZNF76, a novel transcriptional repressor targeting TBP, is modulated by sumoylation
    • Zheng G, Yang YC. ZNF76, a novel transcriptional repressor targeting TBP, is modulated by sumoylation. J Biol Chem 2004;279:42410-21.
    • (2004) J Biol Chem , vol.279 , pp. 42410-42421
    • Zheng, G.1    Yang, Y.C.2
  • 54
    • 0036405612 scopus 로고    scopus 로고
    • Repression of transcription and interference with DNA binding of TATA-binding protein by C-terminal alternatively spliced p53
    • Huang H, Kaku S, Knights C, Park B, Clifford J, Kulesz-Martin M. Repression of transcription and interference with DNA binding of TATA-binding protein by C-terminal alternatively spliced p53. Exp Cell Res 2002;279:248-59.
    • (2002) Exp Cell Res , vol.279 , pp. 248-259
    • Huang, H.1    Kaku, S.2    Knights, C.3    Park, B.4    Clifford, J.5    Kulesz-Martin, M.6
  • 55
    • 1642396456 scopus 로고    scopus 로고
    • Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor
    • Prince S, Carreira S, Vance KW, Abrahams A, Goding CR. Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cancer Res 2004;64:1669-74.
    • (2004) Cancer Res , vol.64 , pp. 1669-1674
    • Prince, S.1    Carreira, S.2    Vance, K.W.3    Abrahams, A.4    Goding, C.R.5
  • 56
    • 0036840499 scopus 로고    scopus 로고
    • Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter
    • Westendorf JJ, Zaidi SK, Cascino JE, et al. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol 2002;22:7982-92.
    • (2002) Mol Cell Biol , vol.22 , pp. 7982-7992
    • Westendorf, J.J.1    Zaidi, S.K.2    Cascino, J.E.3
  • 57
    • 0034614382 scopus 로고    scopus 로고
    • A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia
    • Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia. J Biol Chem 2000;275:651-6.
    • (2000) J Biol Chem , vol.275 , pp. 651-656
    • Lutterbach, B.1    Westendorf, J.J.2    Linggi, B.3    Isaac, S.4    Seto, E.5    Hiebert, S.W.6
  • 58
    • 3843147151 scopus 로고    scopus 로고
    • CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription
    • Nishio H, Walsh MJ. CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription. Proc Natl Acad Sci U S A 2004;101:11257-62.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11257-11262
    • Nishio, H.1    Walsh, M.J.2
  • 59
    • 0032541492 scopus 로고    scopus 로고
    • The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which down-modulates p21WAF1/CIP1/SDI1 in S phase
    • Coqueret O, Berube G, Nepveu A. The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which down-modulates p21WAF1/CIP1/SDI1 in S phase. EMBO J 1998;17:4680-94.
    • (1998) EMBO J , vol.17 , pp. 4680-4694
    • Coqueret, O.1    Berube, G.2    Nepveu, A.3
  • 60
    • 0037112432 scopus 로고    scopus 로고
    • Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells
    • Goulet B, Watson P, Poirier M, et al. Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells. Cancer Res 2002;62:6625-33.
    • (2002) Cancer Res , vol.62 , pp. 6625-6633
    • Goulet, B.1    Watson, P.2    Poirier, M.3
  • 61
    • 0242624636 scopus 로고    scopus 로고
    • Epigenetic targets in hematopoietic malignancies
    • Claus R, Lubbert M. Epigenetic targets in hematopoietic malignancies. Oncogene 2003;22:6489-96.
    • (2003) Oncogene , vol.22 , pp. 6489-6496
    • Claus, R.1    Lubbert, M.2
  • 62
    • 0034046395 scopus 로고    scopus 로고
    • Inhibition of the interferon-γ/signal transducers and activators of transcription (STAT) pathway by hypermethylation at a STAT-binding site in the p21WAF1 promoter region
    • Chen B, He L, Savell VH, Jenkins JJ, Parham DM. Inhibition of the interferon-γ/signal transducers and activators of transcription (STAT) pathway by hypermethylation at a STAT-binding site in the p21WAF1 promoter region. Cancer Res 2000;60:3290-8.
    • (2000) Cancer Res , vol.60 , pp. 3290-3298
    • Chen, B.1    He, L.2    Savell, V.H.3    Jenkins, J.J.4    Parham, D.M.5
  • 63
    • 0037642249 scopus 로고    scopus 로고
    • Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter
    • Zhu WG, Srinivasan K, Dai Z, et al. Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter. Mol Cell Biol 2003;23:4056-65.
    • (2003) Mol Cell Biol , vol.23 , pp. 4056-4065
    • Zhu, W.G.1    Srinivasan, K.2    Dai, Z.3
  • 64
    • 0036525616 scopus 로고    scopus 로고
    • 5′ CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia
    • Roman-Gomez J, Castillejo JA, Jimenez A, et al. 5′ CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia. Blood 2002;99:2291-6.
    • (2002) Blood , vol.99 , pp. 2291-2296
    • Roman-Gomez, J.1    Castillejo, J.A.2    Jimenez, A.3
  • 65
    • 0033539922 scopus 로고    scopus 로고
    • Expression of DNA methyl-transferase (DMT) and the cell cycle in human breast cancer cells
    • Nass SJ, Ferguson AT, El-Ashry D, Nelson WG, Davidson NE. Expression of DNA methyl-transferase (DMT) and the cell cycle in human breast cancer cells. Oncogene 1999;18:7453-61.
    • (1999) Oncogene , vol.18 , pp. 7453-7461
    • Nass, S.J.1    Ferguson, A.T.2    El-Ashry, D.3    Nelson, W.G.4    Davidson, N.E.5
  • 66
    • 0037124073 scopus 로고    scopus 로고
    • Alternate translation occurs within the core coding region of the hepatitis C viral genome
    • Varaklioti A, Vassilaki N, Georgopoulou U, Mavromara P. Alternate translation occurs within the core coding region of the hepatitis C viral genome. J Biol Chem 2002;277:17713-21.
    • (2002) J Biol Chem , vol.277 , pp. 17713-17721
    • Varaklioti, A.1    Vassilaki, N.2    Georgopoulou, U.3    Mavromara, P.4
  • 67
    • 4043094150 scopus 로고    scopus 로고
    • Functional properties of a 16 kDa protein translated from an alternative open reading frame of the core-encoding genomic region of hepatitis C virus
    • Basu A, Steele R, Ray R, Ray RB. Functional properties of a 16 kDa protein translated from an alternative open reading frame of the core-encoding genomic region of hepatitis C virus. J Gen Virol 2004;85:2299-306.
    • (2004) J Gen Virol , vol.85 , pp. 2299-2306
    • Basu, A.1    Steele, R.2    Ray, R.3    Ray, R.B.4
  • 70
    • 0029839485 scopus 로고    scopus 로고
    • Human papillomavirus type 11 and 16 E5 represses p21(Waf1/Sdi1/Cip1) gene expression in fibroblasts and keratinocytes
    • Tsao YP, Li LY, Tsai TC, Chen SL. Human papillomavirus type 11 and 16 E5 represses p21(Waf1/Sdi1/Cip1) gene expression in fibroblasts and keratinocytes. J Virol 1996;70:7535-9.
    • (1996) J Virol , vol.70 , pp. 7535-7539
    • Tsao, Y.P.1    Li, L.Y.2    Tsai, T.C.3    Chen, S.L.4
  • 71
    • 0029686432 scopus 로고    scopus 로고
    • The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein
    • Chen SL, Huang CH, Tsai TC, Lu KY, Tsao YP. The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein. Arch Virol 1996;141:791-800.
    • (1996) Arch Virol , vol.141 , pp. 791-800
    • Chen, S.L.1    Huang, C.H.2    Tsai, T.C.3    Lu, K.Y.4    Tsao, Y.P.5
  • 72
    • 0141731318 scopus 로고    scopus 로고
    • ING1 represses transcription by direct DNA binding and through effects on p53
    • Kataoka H, Bonnefin P, Vieyra D, et al. ING1 represses transcription by direct DNA binding and through effects on p53. Cancer Res 2003;63:5785-92.
    • (2003) Cancer Res , vol.63 , pp. 5785-5792
    • Kataoka, H.1    Bonnefin, P.2    Vieyra, D.3
  • 73
    • 0032537819 scopus 로고    scopus 로고
    • Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1
    • Olson MF, Paterson HF, Marshall CJ. Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. Nature 1998;394:295-9.
    • (1998) Nature , vol.394 , pp. 295-299
    • Olson, M.F.1    Paterson, H.F.2    Marshall, C.J.3
  • 74
    • 3843074330 scopus 로고    scopus 로고
    • Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21(CIP1) levels in androgen-independent human prostate cancer cells
    • Knight-Krajewski S, Welsh CF, Liu Y, et al. Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21(CIP1) levels in androgen-independent human prostate cancer cells. Oncogene 2004;23:5513-22.
    • (2004) Oncogene , vol.23 , pp. 5513-5522
    • Knight-Krajewski, S.1    Welsh, C.F.2    Liu, Y.3
  • 75
    • 0042358634 scopus 로고    scopus 로고
    • Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation
    • Kavurma MM, Khachigian LM. Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation. J Biol Chem 2003;278:32537-43.
    • (2003) J Biol Chem , vol.278 , pp. 32537-32543
    • Kavurma, M.M.1    Khachigian, L.M.2
  • 76
    • 20144363137 scopus 로고    scopus 로고
    • Vascular smooth muscle cell-specific regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1) transcription by Sp1 is mediated via distinct cis-acting positive and negative regulatory elements in the proximal p21(WAF1/Cip1) promoter
    • Kavurma MM, Khachigian LM. Vascular smooth muscle cell-specific regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1) transcription by Sp1 is mediated via distinct cis-acting positive and negative regulatory elements in the proximal p21(WAF1/Cip1) promoter. J Cell Biochem 2004;93:904-16.
    • (2004) J Cell Biochem , vol.93 , pp. 904-916
    • Kavurma, M.M.1    Khachigian, L.M.2
  • 77
    • 17844384528 scopus 로고    scopus 로고
    • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
    • Rangarajan A, Talora C, Okuyama R, et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 2001;20:3427-36.
    • (2001) EMBO J , vol.20 , pp. 3427-3436
    • Rangarajan, A.1    Talora, C.2    Okuyama, R.3
  • 78
    • 4744358492 scopus 로고    scopus 로고
    • Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: Role of p21Cip1 repression
    • Noseda M, Chang L, McLean G, et al. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol Cell Biol 2004;24:8813-22.
    • (2004) Mol Cell Biol , vol.24 , pp. 8813-8822
    • Noseda, M.1    Chang, L.2    McLean, G.3


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