-
3
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
Waga S, Hannon GJ, Beach D, Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994;369:574-8.
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
4
-
-
0030973878
-
New functional activities for the p21 family of CDK inhibitors
-
LaBaer J, Garrett MD, Stevenson LF, et al. New functional activities for the p21 family of CDK inhibitors. Genes Dev 1997;11:847-62.
-
(1997)
Genes Dev
, vol.11
, pp. 847-862
-
-
LaBaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
-
5
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
-
8
-
-
0030743399
-
WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases
-
Ogryzko VV, Wong P, Howard BH. WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases. Mol Cell Biol 1997;17:4877-82.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4877-4882
-
-
Ogryzko, V.V.1
Wong, P.2
Howard, B.H.3
-
9
-
-
2942554804
-
Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle
-
Radhakrishnan SK, Feliciano CS, Najmabadi F, et al. Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle. Oncogene 2004;23:4173-6.
-
(2004)
Oncogene
, vol.23
, pp. 4173-4176
-
-
Radhakrishnan, S.K.1
Feliciano, C.S.2
Najmabadi, F.3
-
12
-
-
7944226274
-
A novel p21(WAF1/CIP1) transcript is highly dependent on p53 for its basal expression in mouse tissues
-
Gartel AL, Radhakrishnan SK, Serfas MS, Kwon YH, Tyner AL. A novel p21(WAF1/CIP1) transcript is highly dependent on p53 for its basal expression in mouse tissues. Oncogene 2004;23:8154-7.
-
(2004)
Oncogene
, vol.23
, pp. 8154-8157
-
-
Gartel, A.L.1
Radhakrishnan, S.K.2
Serfas, M.S.3
Kwon, Y.H.4
Tyner, A.L.5
-
13
-
-
0033080402
-
Transcriptional regulation of the p21(WAF1/CIP1) gene
-
Gartel AL, Tyner AL. Transcriptional regulation of the p21(WAF1/CIP1) gene. Exp Cell Res 1999;246:280-9.
-
(1999)
Exp Cell Res
, vol.246
, pp. 280-289
-
-
Gartel, A.L.1
Tyner, A.L.2
-
14
-
-
0036594890
-
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
-
Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 2002;1:639-49.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 639-649
-
-
Gartel, A.L.1
Tyner, A.L.2
-
16
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 1995;377:552-7.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
18
-
-
0037330625
-
Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes
-
Gartel AL, Shchors K. Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes. Exp Cell Res 2003;283:17-21.
-
(2003)
Exp Cell Res
, vol.283
, pp. 17-21
-
-
Gartel, A.L.1
Shchors, K.2
-
19
-
-
0034724389
-
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
-
Coller HA, Grandori C, Tamayo P, et al. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci U S A 2000;97:3260-5.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3260-3265
-
-
Coller, H.A.1
Grandori, C.2
Tamayo, P.3
-
20
-
-
0034662959
-
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest
-
Claassen GF, Hann SR. A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest. Proc Natl Acad Sci U S A 2000;97:9498-503.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 9498-9503
-
-
Claassen, G.F.1
Hann, S.R.2
-
21
-
-
0035836706
-
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3
-
Gartel AL, Ye X, Goufman E, et al. Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A 2001;98:4510-5.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4510-4515
-
-
Gartel, A.L.1
Ye, X.2
Goufman, E.3
-
22
-
-
0032920581
-
Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells
-
Mitchell KO, El-Deiry WS. Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells. Cell Growth Differ 1999;10:223-30.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 223-230
-
-
Mitchell, K.O.1
El-Deiry, W.S.2
-
23
-
-
0037126303
-
Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
Seoane J, Le HV, Massague J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002;419:729-34.
-
(2002)
Nature
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massague, J.3
-
24
-
-
0037461931
-
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter
-
Wu S, Cetinkaya C, Munoz-Alonso MJ, et al. Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. Oncogene 2003;22:351-60.
-
(2003)
Oncogene
, vol.22
, pp. 351-360
-
-
Wu, S.1
Cetinkaya, C.2
Munoz-Alonso, M.J.3
-
25
-
-
18644373146
-
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering M, Sancho E, Verweij C, et al. The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002;111: 241-50.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
Van De Wetering, M.1
Sancho, E.2
Verweij, C.3
-
26
-
-
0345743712
-
Myc-interacting protein 1 target gene profile: A link to microtubules, extracellular signal-regulated kinase, and cell growth
-
Ziegelbauer J, Wei J, Tjian R. Myc-interacting protein 1 target gene profile: a link to microtubules, extracellular signal-regulated kinase, and cell growth. Proc Natl Acad Sci U S A 2004;101:458-63.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 458-463
-
-
Ziegelbauer, J.1
Wei, J.2
Tjian, R.3
-
27
-
-
12544256261
-
Myc antagonizes ras-mediated growth arrest in leukemia cells through the inhibition of the ras-ERK-p21Cip1 pathway
-
Vaque JP, Navascues J, Shiio Y, et al. Myc Antagonizes Ras-mediated Growth Arrest in Leukemia Cells through the Inhibition of the Ras-ERK-p21Cip1 Pathway. J Biol Chem 2005;280:1112-22.
-
(2005)
J Biol Chem
, vol.280
, pp. 1112-1122
-
-
Vaque, J.P.1
Navascues, J.2
Shiio, Y.3
-
28
-
-
13444270415
-
Myc represses transcription through recruitment of DNA methyltransferase corepressor
-
Brenner C, Deplus R, Didelot C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J 2005;24:336-46.
-
(2005)
EMBO J
, vol.24
, pp. 336-346
-
-
Brenner, C.1
Deplus, R.2
Didelot, C.3
-
29
-
-
0037718341
-
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression
-
Mao DY, Watson JD, Yan PS, et al. Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression. Curr Biol 2003;13:882-6.
-
(2003)
Curr Biol
, vol.13
, pp. 882-886
-
-
Mao, D.Y.1
Watson, J.D.2
Yan, P.S.3
-
30
-
-
0344009714
-
c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis
-
Arango D, Mariadason JM, Wilson AJ, et al. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. Br J Cancer 2003;89:1757-65.
-
(2003)
Br J Cancer
, vol.89
, pp. 1757-1765
-
-
Arango, D.1
Mariadason, J.M.2
Wilson, A.J.3
-
31
-
-
0035910420
-
Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway
-
Chang WT, Kang JJ, Lee KY, et al. Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway. J Biol Chem 2001;276:2221-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 2221-2227
-
-
Chang, W.T.1
Kang, J.J.2
Lee, K.Y.3
-
32
-
-
11244325724
-
Inhibition of p53-mediated transcriptional responses by mithramycin A
-
Koutsodontis G, Kardassis D. Inhibition of p53-mediated transcriptional responses by mithramycin A. Oncogene 2004;23:9190-200.
-
(2004)
Oncogene
, vol.23
, pp. 9190-9200
-
-
Koutsodontis, G.1
Kardassis, D.2
-
33
-
-
0344629425
-
Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression
-
McConnell MJ, Chevallier N, Berkofsky-Fessler W, et al. Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression. Mol Cell Biol 2003;23:9375-88.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9375-9388
-
-
McConnell, M.J.1
Chevallier, N.2
Berkofsky-Fessler, W.3
-
34
-
-
3142631736
-
HIF-1α induces cell cycle arrest by functionally counteracting Myc
-
Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barrett JC, Huang LE. HIF-1α induces cell cycle arrest by functionally counteracting Myc. EMBO J 2004;23: 1949-56.
-
(2004)
EMBO J
, vol.23
, pp. 1949-1956
-
-
Koshiji, M.1
Kageyama, Y.2
Pete, E.A.3
Horikawa, I.4
Barrett, J.C.5
Huang, L.E.6
-
35
-
-
0842277812
-
Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
-
Gui CY, Ngo L, Xu WS, Richon VM, Marks PA. Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. Proc Natl Acad Sci U S A 2004;101:1241-6.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1241-1246
-
-
Gui, C.Y.1
Ngo, L.2
Xu, W.S.3
Richon, V.M.4
Marks, P.A.5
-
36
-
-
5144222440
-
Histone deacetylase inhibitor, Trichostatin A, activates p21(WAF1/CIP1) expression through down-regulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells
-
Li H, Wu X. Histone deacetylase inhibitor, Trichostatin A, activates p21(WAF1/CIP1) expression through down-regulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. Biochem Biophys Res Commun 2004;324:860-7.
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 860-867
-
-
Li, H.1
Wu, X.2
-
37
-
-
0037377761
-
The ΔNp63α phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
-
Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA. The ΔNp63α phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 2003;23: 2264-76.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2264-2276
-
-
Westfall, M.D.1
Mays, D.J.2
Sniezek, J.C.3
Pietenpol, J.A.4
-
38
-
-
2942623616
-
Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation
-
Ando K, Ozaki T, Yamamoto H, et al. Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation. J Biol Chem 2004;279:25549-61.
-
(2004)
J Biol Chem
, vol.279
, pp. 25549-25561
-
-
Ando, K.1
Ozaki, T.2
Yamamoto, H.3
-
39
-
-
0033564832
-
Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck
-
Knecht R, Elez R, Oechler M, Solbach C, von Ilberg C, Strebhardt K. Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck. Cancer Res 1999;59:2794-7.
-
(1999)
Cancer Res
, vol.59
, pp. 2794-2797
-
-
Knecht, R.1
Elez, R.2
Oechler, M.3
Solbach, C.4
Von Ilberg, C.5
Strebhardt, K.6
-
40
-
-
0038018608
-
Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2
-
Kwun HJ, Lee JH, Min do S, Jang KL. Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2. FEBS Lett 2003;544:38-44.
-
(2003)
FEBS Lett
, vol.544
, pp. 38-44
-
-
Kwun, H.J.1
Lee, J.H.2
Do Min, S.3
Jang, K.L.4
-
41
-
-
0033104956
-
Control of cell cycle progression by c-Jun is p53 dependent
-
Schreiber M, Kolbus A, Piu F, et al. Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev 1999;13:607-19.
-
(1999)
Genes Dev
, vol.13
, pp. 607-619
-
-
Schreiber, M.1
Kolbus, A.2
Piu, F.3
-
42
-
-
6344253201
-
Mechanisms of human papillomavirus-induced oncogenesis
-
Munger K, Baldwin A, Edwards KM, et al. Mechanisms of human papillomavirus-induced oncogenesis. J Virol 2004;78:11451-60.
-
(2004)
J Virol
, vol.78
, pp. 11451-11460
-
-
Munger, K.1
Baldwin, A.2
Edwards, K.M.3
-
43
-
-
4644276886
-
Activation of RB/E2F signaling pathway is required for the modulation of hepatitis C virus core protein-induced cell growth in liver and non-liver cells
-
Hassan M, Ghozlan H, Abdel-Kader O. Activation of RB/E2F signaling pathway is required for the modulation of hepatitis C virus core protein-induced cell growth in liver and non-liver cells. Cell Signal 2004;16:1375-85.
-
(2004)
Cell Signal
, vol.16
, pp. 1375-1385
-
-
Hassan, M.1
Ghozlan, H.2
Abdel-Kader, O.3
-
44
-
-
0035148645
-
Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner
-
Majumder M, Ghosh AK, Steele R, Ray R, Ray RB. Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner. J Virol 2001;75:1401-7.
-
(2001)
J Virol
, vol.75
, pp. 1401-1407
-
-
Majumder, M.1
Ghosh, A.K.2
Steele, R.3
Ray, R.4
Ray, R.B.5
-
45
-
-
0034852454
-
p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3
-
Kwun HJ, Jung EY, Ahn JY, Lee MN, Jang KL. p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3. J Gen Virol 2001;82:2235-41.
-
(2001)
J Gen Virol
, vol.82
, pp. 2235-2241
-
-
Kwun, H.J.1
Jung, E.Y.2
Ahn, J.Y.3
Lee, M.N.4
Jang, K.L.5
-
46
-
-
0034595098
-
Transcriptional repression of p21(Waf1/Cip1/Sdi1) gene by c-jun through Sp1 site
-
Wang CH, Tsao YP, Chen HJ, Chen HL, Wang HW, Chen SL. Transcriptional repression of p21(Waf1/Cip1/Sdi1) gene by c-jun through Sp1 site. Biochem Biophys Res Commun 2000;270:303-10.
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 303-310
-
-
Wang, C.H.1
Tsao, Y.P.2
Chen, H.J.3
Chen, H.L.4
Wang, H.W.5
Chen, S.L.6
-
47
-
-
0032832571
-
c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1
-
Kardassis D, Papakosta P, Pardali K, Moustakas A. c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1. J Biol Chem 1999;274:29572-81.
-
(1999)
J Biol Chem
, vol.274
, pp. 29572-29581
-
-
Kardassis, D.1
Papakosta, P.2
Pardali, K.3
Moustakas, A.4
-
48
-
-
0035812298
-
Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway
-
Ahn JY, Chung EY, Kwun HJ, Jang KL. Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway. Gene 2001;275:163-8.
-
(2001)
Gene
, vol.275
, pp. 163-168
-
-
Ahn, J.Y.1
Chung, E.Y.2
Kwun, H.J.3
Jang, K.L.4
-
49
-
-
0037383786
-
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene
-
Lagger G, Doetzlhofer A, Schuettengruber B, et al. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol Cell Biol 2003;23:2669-79.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2669-2679
-
-
Lagger, G.1
Doetzlhofer, A.2
Schuettengruber, B.3
-
50
-
-
0037042205
-
Cooperative repression of cyclin-dependent kinase inhibitor p21 gene expression by hepatitis B virus X protein and hepatitis C virus core protein
-
Han HJ, Jung EY, Lee WJ, Jang KL. Cooperative repression of cyclin-dependent kinase inhibitor p21 gene expression by hepatitis B virus X protein and hepatitis C virus core protein. FEBS Lett 2002;518:169-72.
-
(2002)
FEBS Lett
, vol.518
, pp. 169-172
-
-
Han, H.J.1
Jung, E.Y.2
Lee, W.J.3
Jang, K.L.4
-
51
-
-
0030879868
-
Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins
-
Prabhu S, Ignatova A, Park ST, Sun XH. Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins. Mol Cell Biol 1997;17:5888-96.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5888-5896
-
-
Prabhu, S.1
Ignatova, A.2
Park, S.T.3
Sun, X.H.4
-
52
-
-
12144286826
-
Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD
-
Kim JY, Chu K, Kim HJ, et al. Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD. Mol Endocrinol 2004;18:776-90.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 776-790
-
-
Kim, J.Y.1
Chu, K.2
Kim, H.J.3
-
53
-
-
5644261273
-
ZNF76, a novel transcriptional repressor targeting TBP, is modulated by sumoylation
-
Zheng G, Yang YC. ZNF76, a novel transcriptional repressor targeting TBP, is modulated by sumoylation. J Biol Chem 2004;279:42410-21.
-
(2004)
J Biol Chem
, vol.279
, pp. 42410-42421
-
-
Zheng, G.1
Yang, Y.C.2
-
54
-
-
0036405612
-
Repression of transcription and interference with DNA binding of TATA-binding protein by C-terminal alternatively spliced p53
-
Huang H, Kaku S, Knights C, Park B, Clifford J, Kulesz-Martin M. Repression of transcription and interference with DNA binding of TATA-binding protein by C-terminal alternatively spliced p53. Exp Cell Res 2002;279:248-59.
-
(2002)
Exp Cell Res
, vol.279
, pp. 248-259
-
-
Huang, H.1
Kaku, S.2
Knights, C.3
Park, B.4
Clifford, J.5
Kulesz-Martin, M.6
-
55
-
-
1642396456
-
Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor
-
Prince S, Carreira S, Vance KW, Abrahams A, Goding CR. Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cancer Res 2004;64:1669-74.
-
(2004)
Cancer Res
, vol.64
, pp. 1669-1674
-
-
Prince, S.1
Carreira, S.2
Vance, K.W.3
Abrahams, A.4
Goding, C.R.5
-
56
-
-
0036840499
-
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter
-
Westendorf JJ, Zaidi SK, Cascino JE, et al. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol 2002;22:7982-92.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7982-7992
-
-
Westendorf, J.J.1
Zaidi, S.K.2
Cascino, J.E.3
-
57
-
-
0034614382
-
A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia
-
Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia. J Biol Chem 2000;275:651-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 651-656
-
-
Lutterbach, B.1
Westendorf, J.J.2
Linggi, B.3
Isaac, S.4
Seto, E.5
Hiebert, S.W.6
-
58
-
-
3843147151
-
CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription
-
Nishio H, Walsh MJ. CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription. Proc Natl Acad Sci U S A 2004;101:11257-62.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 11257-11262
-
-
Nishio, H.1
Walsh, M.J.2
-
59
-
-
0032541492
-
The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which down-modulates p21WAF1/CIP1/SDI1 in S phase
-
Coqueret O, Berube G, Nepveu A. The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which down-modulates p21WAF1/CIP1/SDI1 in S phase. EMBO J 1998;17:4680-94.
-
(1998)
EMBO J
, vol.17
, pp. 4680-4694
-
-
Coqueret, O.1
Berube, G.2
Nepveu, A.3
-
60
-
-
0037112432
-
Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells
-
Goulet B, Watson P, Poirier M, et al. Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells. Cancer Res 2002;62:6625-33.
-
(2002)
Cancer Res
, vol.62
, pp. 6625-6633
-
-
Goulet, B.1
Watson, P.2
Poirier, M.3
-
61
-
-
0242624636
-
Epigenetic targets in hematopoietic malignancies
-
Claus R, Lubbert M. Epigenetic targets in hematopoietic malignancies. Oncogene 2003;22:6489-96.
-
(2003)
Oncogene
, vol.22
, pp. 6489-6496
-
-
Claus, R.1
Lubbert, M.2
-
62
-
-
0034046395
-
Inhibition of the interferon-γ/signal transducers and activators of transcription (STAT) pathway by hypermethylation at a STAT-binding site in the p21WAF1 promoter region
-
Chen B, He L, Savell VH, Jenkins JJ, Parham DM. Inhibition of the interferon-γ/signal transducers and activators of transcription (STAT) pathway by hypermethylation at a STAT-binding site in the p21WAF1 promoter region. Cancer Res 2000;60:3290-8.
-
(2000)
Cancer Res
, vol.60
, pp. 3290-3298
-
-
Chen, B.1
He, L.2
Savell, V.H.3
Jenkins, J.J.4
Parham, D.M.5
-
63
-
-
0037642249
-
Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter
-
Zhu WG, Srinivasan K, Dai Z, et al. Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter. Mol Cell Biol 2003;23:4056-65.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4056-4065
-
-
Zhu, W.G.1
Srinivasan, K.2
Dai, Z.3
-
64
-
-
0036525616
-
5′ CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia
-
Roman-Gomez J, Castillejo JA, Jimenez A, et al. 5′ CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia. Blood 2002;99:2291-6.
-
(2002)
Blood
, vol.99
, pp. 2291-2296
-
-
Roman-Gomez, J.1
Castillejo, J.A.2
Jimenez, A.3
-
65
-
-
0033539922
-
Expression of DNA methyl-transferase (DMT) and the cell cycle in human breast cancer cells
-
Nass SJ, Ferguson AT, El-Ashry D, Nelson WG, Davidson NE. Expression of DNA methyl-transferase (DMT) and the cell cycle in human breast cancer cells. Oncogene 1999;18:7453-61.
-
(1999)
Oncogene
, vol.18
, pp. 7453-7461
-
-
Nass, S.J.1
Ferguson, A.T.2
El-Ashry, D.3
Nelson, W.G.4
Davidson, N.E.5
-
66
-
-
0037124073
-
Alternate translation occurs within the core coding region of the hepatitis C viral genome
-
Varaklioti A, Vassilaki N, Georgopoulou U, Mavromara P. Alternate translation occurs within the core coding region of the hepatitis C viral genome. J Biol Chem 2002;277:17713-21.
-
(2002)
J Biol Chem
, vol.277
, pp. 17713-17721
-
-
Varaklioti, A.1
Vassilaki, N.2
Georgopoulou, U.3
Mavromara, P.4
-
67
-
-
4043094150
-
Functional properties of a 16 kDa protein translated from an alternative open reading frame of the core-encoding genomic region of hepatitis C virus
-
Basu A, Steele R, Ray R, Ray RB. Functional properties of a 16 kDa protein translated from an alternative open reading frame of the core-encoding genomic region of hepatitis C virus. J Gen Virol 2004;85:2299-306.
-
(2004)
J Gen Virol
, vol.85
, pp. 2299-2306
-
-
Basu, A.1
Steele, R.2
Ray, R.3
Ray, R.B.4
-
69
-
-
0023336261
-
Avian sarcoma virus 17 carries the jun oncogene
-
Maki Y, Bos TJ, Davis C, Starbuck M, Vogt PK. Avian sarcoma virus 17 carries the jun oncogene. Proc Natl Acad Sci U S A 1987;84:2848-52.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 2848-2852
-
-
Maki, Y.1
Bos, T.J.2
Davis, C.3
Starbuck, M.4
Vogt, P.K.5
-
70
-
-
0029839485
-
Human papillomavirus type 11 and 16 E5 represses p21(Waf1/Sdi1/Cip1) gene expression in fibroblasts and keratinocytes
-
Tsao YP, Li LY, Tsai TC, Chen SL. Human papillomavirus type 11 and 16 E5 represses p21(Waf1/Sdi1/Cip1) gene expression in fibroblasts and keratinocytes. J Virol 1996;70:7535-9.
-
(1996)
J Virol
, vol.70
, pp. 7535-7539
-
-
Tsao, Y.P.1
Li, L.Y.2
Tsai, T.C.3
Chen, S.L.4
-
71
-
-
0029686432
-
The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein
-
Chen SL, Huang CH, Tsai TC, Lu KY, Tsao YP. The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein. Arch Virol 1996;141:791-800.
-
(1996)
Arch Virol
, vol.141
, pp. 791-800
-
-
Chen, S.L.1
Huang, C.H.2
Tsai, T.C.3
Lu, K.Y.4
Tsao, Y.P.5
-
72
-
-
0141731318
-
ING1 represses transcription by direct DNA binding and through effects on p53
-
Kataoka H, Bonnefin P, Vieyra D, et al. ING1 represses transcription by direct DNA binding and through effects on p53. Cancer Res 2003;63:5785-92.
-
(2003)
Cancer Res
, vol.63
, pp. 5785-5792
-
-
Kataoka, H.1
Bonnefin, P.2
Vieyra, D.3
-
73
-
-
0032537819
-
Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1
-
Olson MF, Paterson HF, Marshall CJ. Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. Nature 1998;394:295-9.
-
(1998)
Nature
, vol.394
, pp. 295-299
-
-
Olson, M.F.1
Paterson, H.F.2
Marshall, C.J.3
-
74
-
-
3843074330
-
Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21(CIP1) levels in androgen-independent human prostate cancer cells
-
Knight-Krajewski S, Welsh CF, Liu Y, et al. Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21(CIP1) levels in androgen-independent human prostate cancer cells. Oncogene 2004;23:5513-22.
-
(2004)
Oncogene
, vol.23
, pp. 5513-5522
-
-
Knight-Krajewski, S.1
Welsh, C.F.2
Liu, Y.3
-
75
-
-
0042358634
-
Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation
-
Kavurma MM, Khachigian LM. Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation. J Biol Chem 2003;278:32537-43.
-
(2003)
J Biol Chem
, vol.278
, pp. 32537-32543
-
-
Kavurma, M.M.1
Khachigian, L.M.2
-
76
-
-
20144363137
-
Vascular smooth muscle cell-specific regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1) transcription by Sp1 is mediated via distinct cis-acting positive and negative regulatory elements in the proximal p21(WAF1/Cip1) promoter
-
Kavurma MM, Khachigian LM. Vascular smooth muscle cell-specific regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1) transcription by Sp1 is mediated via distinct cis-acting positive and negative regulatory elements in the proximal p21(WAF1/Cip1) promoter. J Cell Biochem 2004;93:904-16.
-
(2004)
J Cell Biochem
, vol.93
, pp. 904-916
-
-
Kavurma, M.M.1
Khachigian, L.M.2
-
77
-
-
17844384528
-
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A, Talora C, Okuyama R, et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 2001;20:3427-36.
-
(2001)
EMBO J
, vol.20
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
-
78
-
-
4744358492
-
Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: Role of p21Cip1 repression
-
Noseda M, Chang L, McLean G, et al. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol Cell Biol 2004;24:8813-22.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8813-8822
-
-
Noseda, M.1
Chang, L.2
McLean, G.3
|