Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

Molecular and Cellular Neurosciences

Volumn 16, Issue 2, 2000, Pages 168-183

  Li, Shi Hua ^a   Li, He ^a   Torre, Enrique R ^a   Li, Xiao Jiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HUNTINGTIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUNTINGTON CHOREA; NERVE ENDING; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SYNAPSE VESICLE;

ANIMALIA;

EID: 0033848272     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2000.0858     Document Type: Article

References (44)

1. Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon
2. Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons
3. Tyrosinated and detyrosinated microtubules in axonal processes of cerebellar macroneurons grown in culture
4. Fast transport and retrograde movement of huntingtin and HAP 1 in axons
5. Growth of a rat neuroblastoma cell line in serum-free supplemented medium
6. Comparison of hippocampal dendritic spines in culture and in brain
7. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
8. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
9. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
10. Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin
11. Sense and antisense transfection analysis of tau function: Tau influences net microtubule assembly, neurite outgrowth and neuritic stability
12. The expression of acetylated microtubules during axonal and dendritic growth in cerebellar macroneurons which develop in vitro
13. The economics of neurite outgrowth - The addition of new membrane to growing axons
14. Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein
15. 2+/calmodulin-dependent protein kinase II in Neuro2a and NG108-15 neuroblastoma cell lines promotes neurite outgrowth and growth cone motility
16. Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies
17. The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): Comparison with huntingtin in rat and human
18. Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology
19. A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
20. Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth
21. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
22. Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin
23. Neuronotypic differentiation results in reduced levels and altered distribution of synaptophysin in PC12 cells
24. Distribution and possible interactions of actin-associated proteins and cell adhesion molecules of nerve growth cones
25. Localization of a metabotropic glutamate receptor, mGluR7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: An electron microscope study in the rat
26. Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice
27. A human HAP1 homologue. Cloning, expression, and interaction with huntingtin
28. Association of HAP1 isoforms with a unique cytoplasmic structure
29. Interaction of huntingtin-associated protein with dynactin P150Glued
30. Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats
31. A huntingtin-associated protein enriched in brain with implications for pathology
32. Huntingtin-associated protein (HAP1): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase
33. Cytoskeletal reorganization underlying growth cone motility
34. Differential localization of vesicular acetylcholine and monoamine transporters in PC12 cells but not CHO cells
35. Analysis of Huntingtin-associated protein I in mouse brain and immortalized striatal neurons
36. Spontaneous morphological changes by overexpression of the growth-associated protein B-50/GAP-43 in a PC12 cell line
37. 2+/calmodulin-dependent protein kinase II in neuroblastoma cells - H-7 promotes neurite outgrowth
38. The expression of Huntingtin-associated protein (HAP1) mRNA in developing, adult and ageing rat CNS: Implications for Huntington's disease neuropathology
39. Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease
40. Two activators of microtubule-based vesicle transport
41. The synaptic vesicle cycle: A cascade of protein-protein interactions
42. Protein synthesis within dendrites: Glycosylation of newly synthesized proteins in dendrites of hippocampal neurons in culture
43. Impaired synaptic plasticity in mice carrying the Huntington's disease mutation
44. Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways