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Volumn 374, Issue , 2013, Pages 53-80

Molecular biology of drug resistance in Mycobacterium tuberculosis

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIINFECTIVE AGENT; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; PYRAZINAMIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; STREPTOMYCIN;

EID: 84892698163     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/82-2012-279     Document Type: Article
Times cited : (150)

References (134)
  • 1
    • 79953279193 scopus 로고    scopus 로고
    • Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
    • Adams KN, Takaki K, Connolly LE et al (2011) Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145:39-53
    • (2011) Cell , vol.145 , pp. 39-53
    • Adams, K.N.1    Takaki, K.2    Connolly, L.E.3
  • 2
    • 0031793411 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in mycobacterium fortuitum and mycobacterium tuberculosis
    • Ainsa JA, Blokpoel MC, Otal I, Young DB, De Smet KA, Martin C (1998) Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in mycobacterium fortuitum and mycobacterium tuberculosis. J Bacteriol 180:5836-5843
    • (1998) J Bacteriol , vol.180 , pp. 5836-5843
    • Ainsa, J.A.1    Blokpoel, M.C.2    Otal, I.3    Young, D.B.4    De Smet, K.A.5    Martin, C.6
  • 3
    • 0029842790 scopus 로고    scopus 로고
    • Characterization of the chromosomal aminoglycoside 2'-N-acetyltransferase gene from mycobacterium fortuitum
    • Ainsa JA, Martin C, Gicquel B, Gomez-Lus R (1996) Characterization of the chromosomal aminoglycoside 2'-N-acetyltransferase gene from mycobacterium fortuitum. Antimicrob Agents Chemother 40:2350-2355
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2350-2355
    • Ainsa, J.A.1    Martin, C.2    Gicquel, B.3    Gomez-Lus, R.4
  • 5
    • 0000148162 scopus 로고    scopus 로고
    • Regulation of chromosomally mediated multiple antibiotic resistance: The mar regulon
    • Alekshun MN, Levy SB (1997) Regulation of chromosomally mediated multiple antibiotic resistance: The mar regulon. Antimicrob Agents Chemother 41:2067-2075
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2067-2075
    • Alekshun, M.N.1    Levy, S.B.2
  • 6
    • 33748693294 scopus 로고    scopus 로고
    • The biological cost of mutational antibiotic resistance: Any practical conclusions?
    • Andersson DI (2006) The biological cost of mutational antibiotic resistance: Any practical conclusions? Curr Opin Microbiol 9:461-465
    • (2006) Curr Opin Microbiol , vol.9 , pp. 461-465
    • Andersson, D.I.1
  • 7
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: Is it possible to reverse resistance? Nature reviews
    • Andersson DI, Hughes D (2010) Antibiotic resistance and its cost: Is it possible to reverse resistance? Nature reviews. Microbiology 8:260-271
    • (2010) Microbiology , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 8
    • 0032870940 scopus 로고    scopus 로고
    • The biological cost of antibiotic resistance
    • Andersson DI, Levin BR (1999) The biological cost of antibiotic resistance. Curr Opin Microbiol 2:489-493
    • (1999) Curr Opin Microbiol , vol.2 , pp. 489-493
    • Andersson, D.I.1    Levin, B.R.2
  • 9
    • 33745595381 scopus 로고    scopus 로고
    • Intrinsic macrolide resistance of the mycobacterium tuberculosis complex is inducible
    • Andini N, Nash KA (2006) Intrinsic macrolide resistance of the mycobacterium tuberculosis complex is inducible. Antimicrob Agents Chemother 50:2560-2562
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2560-2562
    • Andini, N.1    Nash, K.A.2
  • 10
    • 21844443566 scopus 로고    scopus 로고
    • The quinolones: Past, present, and future
    • Andriole VT (2005) The quinolones: Past, present, and future. Clin Infect Dis 41(Suppl 2):S113-S119
    • (2005) Clin Infect Dis , vol.41 , Issue.SUPPL. 2
    • Andriole, V.T.1
  • 11
    • 0036774971 scopus 로고    scopus 로고
    • Selection of in vitro mutants of pyrazinamide-resistant mycobacterium tuberculosis
    • Bamaga M, Wright DJ, Zhang H (2002) Selection of in vitro mutants of pyrazinamide-resistant mycobacterium tuberculosis. Int J Antimicrob Agents 20:275-281
    • (2002) Int J Antimicrob Agents , vol.20 , pp. 275-281
    • Bamaga, M.1    Wright, D.J.2    Zhang, H.3
  • 13
    • 0036270739 scopus 로고    scopus 로고
    • Evaluation of a nutrient starvation model of mycobacterium tuberculosis persistence by gene and protein expression profiling
    • Betts JC, Lukey PT, Robb LC, McAdam RA, Duncan K (2002) Evaluation of a nutrient starvation model of mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol 43:717-731
    • (2002) Mol Microbiol , vol.43 , pp. 717-731
    • Betts, J.C.1    Lukey, P.T.2    Robb, L.C.3    McAdam, R.A.4    Duncan, K.5
  • 15
    • 0033797547 scopus 로고    scopus 로고
    • Expression of mycobacterium smegmatis pyrazinamidase in mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides
    • Boshoff HI, Mizrahi V (2000) Expression of mycobacterium smegmatis pyrazinamidase in mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides. J Bacteriol 182:5479-5485
    • (2000) J Bacteriol , vol.182 , pp. 5479-5485
    • Boshoff, H.I.1    Mizrahi, V.2
  • 17
    • 0037347862 scopus 로고    scopus 로고
    • Association of mycothiol with protection of mycobacterium tuberculosis from toxic oxidants and antibiotics
    • Buchmeier NA, Newton GL, Koledin T, Fahey RC (2003) Association of mycothiol with protection of mycobacterium tuberculosis from toxic oxidants and antibiotics. Mol Microbiol 47:1723-1732
    • (2003) Mol Microbiol , vol.47 , pp. 1723-1732
    • Buchmeier, N.A.1    Newton, G.L.2    Koledin, T.3    Fahey, R.C.4
  • 18
    • 84855286330 scopus 로고    scopus 로고
    • The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance
    • Burian J, Ramon-Garcia S, Sweet G, Gomez-Velasco A, Av-Gay Y, Thompson CJ (2012) The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance. J Biol Chem 287:299-310
    • (2012) J Biol Chem , vol.287 , pp. 299-310
    • Burian, J.1    Ramon-Garcia, S.2    Sweet, G.3    Gomez-Velasco, A.4    Av-Gay, Y.5    Thompson, C.J.6
  • 20
    • 79955539272 scopus 로고    scopus 로고
    • Molecular detection of mutations associated with first-and second-line drug resistance compared with conventional drug susceptibility testing of mycobacterium tuberculosis
    • Campbell PJ, Morlock GP, Sikes RD et al (2011) Molecular detection of mutations associated with first-and second-line drug resistance compared with conventional drug susceptibility testing of mycobacterium tuberculosis. Antimicrob Agents Chemother 55:2032-2041
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2032-2041
    • Campbell, P.J.1    Morlock, G.P.2    Sikes, R.D.3
  • 21
    • 0028859485 scopus 로고
    • Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis?
    • Chambers HF, Moreau D, Yajko D et al (1995) Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis? Antimicrob Agents Chemother 39:2620-2624
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2620-2624
    • Chambers, H.F.1    Moreau, D.2    Yajko, D.3
  • 22
    • 75349083412 scopus 로고    scopus 로고
    • Protein kinase and phosphatase signaling in mycobacterium tuberculosis physiology and pathogenesis
    • Chao J, Wong D, Zheng X, Poirier V, Bach H, Hmama Z, Av-Gay Y (2010) Protein kinase and phosphatase signaling in mycobacterium tuberculosis physiology and pathogenesis. Biochim Biophys Acta 1804:620-627
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 620-627
    • Chao, J.1    Wong, D.2    Zheng, X.3    Poirier, V.4    Bach, H.5    Hmama, Z.6    Av-Gay, Y.7
  • 24
    • 63149084649 scopus 로고    scopus 로고
    • The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates
    • Colangeli R, Haq A, Arcus VL et al (2009) The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates. Proc Natl Acad Sci USA 106:4414-4418
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4414-4418
    • Colangeli, R.1    Haq, A.2    Arcus, V.L.3
  • 25
    • 20144387448 scopus 로고    scopus 로고
    • The mycobacterium tuberculosis inia gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol
    • Colangeli R, Helb D, Sridharan S et al (2005) The mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol. Mol Microbiol 55:1829-1840
    • (2005) Mol Microbiol , vol.55 , pp. 1829-1840
    • Colangeli, R.1    Helb, D.2    Sridharan, S.3
  • 26
    • 34347333558 scopus 로고    scopus 로고
    • Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M tuberculosis
    • Colangeli R, Helb D, Vilcheze C et al (2007) Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M tuberculosis. PLoS Pathog 3:e87
    • (2007) PLoS Pathog , vol.3
    • Colangeli, R.1    Helb, D.2    Vilcheze, C.3
  • 27
    • 84555209977 scopus 로고    scopus 로고
    • Whole-genome sequencing of rifampicin-resistant mycobacterium tuberculosis strains identifies compensatory mutations in rna polymerase genes
    • Comas I, Borrell S, Roetzer A et al (2012) Whole-genome sequencing of rifampicin-resistant mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes. Nat Genet 44:106-110
    • (2012) Nat Genet , vol.44 , pp. 106-110
    • Comas, I.1    Borrell, S.2    Roetzer, A.3
  • 29
    • 80053130409 scopus 로고    scopus 로고
    • Antibiotic resistance is ancient
    • D'Costa VM, King CE, Kalan L et al (2011) Antibiotic resistance is ancient. Nature 477:457-461
    • (2011) Nature , vol.477 , pp. 457-461
    • D'Costa, V.M.1    King, C.E.2    Kalan, L.3
  • 33
    • 84892755846 scopus 로고    scopus 로고
    • The Nexus of oxidative stress responses and antibiotic resistance mechanisms in escherichia coli and Salmonella
    • White DG, Alekshun MN, McDermott PF, Levy SB (eds American Society for Microbiology, Washington, DC
    • Demple B (2005) The Nexus of oxidative stress responses and antibiotic resistance mechanisms in escherichia coli and Salmonella. In: White DG, Alekshun MN, McDermott PF, Levy SB (eds) Frontiers in antimicrobial resistance: A tribute to Stuart B. Levy. American Society for Microbiology, Washington, DC, pp 191-197
    • (2005) Frontiers In Antimicrobial Resistance: A Tribute To Stuart B Levy , pp. 191-197
    • Demple, B.1
  • 34
    • 77955447693 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice
    • Dhar N, McKinney JD (2010) Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice. Proc National Acad Sci USA 107:12275-12280
    • (2010) Proc National Acad Sci USA , vol.107 , pp. 12275-12280
    • Dhar, N.1    McKinney, J.D.2
  • 35
    • 33847719510 scopus 로고    scopus 로고
    • From magic bullets back to the magic mountain: The rise of extensively drug-resistant tuberculosis
    • Dorman SE, Chaisson RE (2007) From magic bullets back to the magic mountain: The rise of extensively drug-resistant tuberculosis. Nat Med 13:295-298
    • (2007) Nat Med , vol.13 , pp. 295-298
    • Dorman, S.E.1    Chaisson, R.E.2
  • 36
    • 4644223350 scopus 로고    scopus 로고
    • Prospects for new antitubercular drugs
    • Duncan K, Barry CE 3rd (2004) Prospects for new antitubercular drugs. Curr Opin Microbiol 7:460-465
    • (2004) Curr Opin Microbiol , vol.7 , pp. 460-465
    • Duncan, K.1    Barry III, C.E.2
  • 37
    • 79956058701 scopus 로고    scopus 로고
    • Comparison of clinical isolates and in vitro selected mutants reveals that tlya is not a sensitive genetic marker for capreomycin resistance in mycobacterium tuberculosis
    • Engstrom A, Perskvist N, Werngren J, Hoffner SE, Jureen P (2011) Comparison of clinical isolates and in vitro selected mutants reveals that tlyA is not a sensitive genetic marker for capreomycin resistance in mycobacterium tuberculosis. J Antimicrob Chemother 66:1247-1254
    • (2011) J Antimicrob Chemother , vol.66 , pp. 1247-1254
    • Engstrom, A.1    Perskvist, N.2    Werngren, J.3    Hoffner, S.E.4    Jureen, P.5
  • 38
    • 20344376453 scopus 로고    scopus 로고
    • Biochemistry protein that mimics dna helps tuberculosis bacteria resist antibiotics
    • Ferber D (2005) Biochemistry. Protein that mimics DNA helps tuberculosis bacteria resist antibiotics. Science 308:1393
    • (2005) Science , vol.308 , pp. 1393
    • Ferber, D.1
  • 39
    • 14044262957 scopus 로고    scopus 로고
    • Genetic analysis of the beta-lactamases of mycobacterium tuberculosis and mycobacterium smegmatis and susceptibility to beta-lactam antibiotics
    • Flores AR, Parsons LM, Pavelka MS Jr (2005) Genetic analysis of the beta-lactamases of mycobacterium tuberculosis and mycobacterium smegmatis and susceptibility to beta-lactam antibiotics. Microbiology 151:521-532
    • (2005) Microbiology , vol.151 , pp. 521-532
    • Flores, A.R.1    Parsons, L.M.2    PavelkaJr., M.S.3
  • 40
  • 41
    • 0141677776 scopus 로고    scopus 로고
    • Requirement for kasB in mycobacterium mycolic acid biosyn thesis cell wall impermeability and intracellular survival: Implications for therapy
    • Gao LY, Laval F, Lawson EH et al (2003) Requirement for kasB in mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: Implications for therapy. Mol Microbiol 49:1547-1563
    • (2003) Mol Microbiol , vol.49 , pp. 1547-1563
    • Gao, L.Y.1    Laval, F.2    Lawson, E.H.3
  • 42
    • 43249101747 scopus 로고    scopus 로고
    • Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum
    • Garton NJ, Waddell SJ, Sherratt AL et al (2008) Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum. PLoS medicine 5:e75
    • (2008) PLoS medicine , vol.5
    • Garton, N.J.1    Waddell, S.J.2    Sherratt, A.L.3
  • 43
    • 84859429244 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis: Success through dormancy
    • Gengenbacher M, Kaufmann SH (2012) Mycobacterium tuberculosis: Success through dormancy. FEMS Microbiol Rev 36:514-532
    • (2012) FEMS Microbiol Rev , vol.36 , pp. 514-532
    • Gengenbacher, M.1    Kaufmann, S.H.2
  • 44
    • 0036921959 scopus 로고    scopus 로고
    • Multiple drug-resistant mycobacterium tuberculosis: Evidence for changing fitness following passage through human hosts
    • Gillespie SH, Billington OJ, Breathnach A, McHugh TD (2002) Multiple drug-resistant mycobacterium tuberculosis: Evidence for changing fitness following passage through human hosts. Microbial Drug Resist 8:273-279
    • (2002) Microbial Drug Resist , vol.8 , pp. 273-279
    • Gillespie, S.H.1    Billington, O.J.2    Breathnach, A.3    McHugh, T.D.4
  • 45
    • 0347091999 scopus 로고    scopus 로고
    • M tuberculosis persistence, latency, and drug tolerance
    • Gomez JE, McKinney JD (2004) M tuberculosis persistence, latency, and drug tolerance. Tuberculosis 84:29-44
    • (2004) Tuberculosis , vol.84 , pp. 29-44
    • Gomez, J.E.1    McKinney, J.D.2
  • 46
    • 77956924551 scopus 로고    scopus 로고
    • Characterization of a chromosomal toxin-antitoxin rv1102c-rv1103c system in mycobacterium tuberculosis
    • Han JS, Lee JJ, Anandan T et al (2010) Characterization of a chromosomal toxin-antitoxin, Rv1102c-Rv1103c system in mycobacterium tuberculosis. Biochemical Biophys Res Commun 400:293-298
    • (2010) Biochemical Biophys Res Commun , vol.400 , pp. 293-298
    • Han, J.S.1    Lee, J.J.2    Anandan, T.3
  • 47
    • 48749089081 scopus 로고    scopus 로고
    • Role of global regulators and nucleotide metabolism in antibiotic tolerance in escherichia coli
    • Hansen S, Lewis K, Vulic M (2008) Role of global regulators and nucleotide metabolism in antibiotic tolerance in escherichia coli. Antimicrobial Agents Chemother 52:2718-2726
    • (2008) Antimicrobial Agents Chemother , vol.52 , pp. 2718-2726
    • Hansen, S.1    Lewis, K.2    Vulic, M.3
  • 49
    • 0036714331 scopus 로고    scopus 로고
    • Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymerase
    • Hengge-Aronis R (2002) Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymerase. Microbiol Mol Biol Rev: MMBR 66:373-395
    • (2002) Microbiol Mol Biol Rev: MMBR , vol.66 , pp. 373-395
    • Hengge-Aronis, R.1
  • 50
    • 41649116701 scopus 로고    scopus 로고
    • Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure
    • Hoffmann C, Leis A, Niederweis M, Plitzko JM, Engelhardt H (2008) Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure. Proc Natl Acad Sci USA 105:3963-3967
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3963-3967
    • Hoffmann, C.1    Leis, A.2    Niederweis, M.3    Plitzko, J.M.4    Engelhardt, H.5
  • 51
    • 79959816757 scopus 로고    scopus 로고
    • Performance assessment of the GenoType MTBDRsl test and DNA sequencing for detection of second-line and ethambutol drug resistance among patients infected with multidrug-resistant mycobacterium tuberculosis
    • Huang WL, Chi TL, Wu MH, Jou R (2011) Performance assessment of the GenoType MTBDRsl test and DNA sequencing for detection of second-line and ethambutol drug resistance among patients infected with multidrug-resistant mycobacterium tuberculosis. J Clin Microbiol 49:2502-2508
    • (2011) J Clin Microbiol , vol.49 , pp. 2502-2508
    • Huang, W.L.1    Chi, T.L.2    Wu, M.H.3    Jou, R.4
  • 52
    • 35649007240 scopus 로고    scopus 로고
    • Irreversible inhibition of the mycobacterium tuberculosis beta-lactamase by clavulanate
    • Hugonnet JE, Blanchard JS (2007) Irreversible inhibition of the mycobacterium tuberculosis beta-lactamase by clavulanate. Biochemistry 46:11998-12004
    • (2007) Biochemistry , vol.46 , pp. 11998-12004
    • Hugonnet, J.E.1    Blanchard, J.S.2
  • 53
    • 0026443736 scopus 로고
    • Manganese-mediated oxidative damage of cellular and isolated DNA by isoniazid and related hydrazines: Non-Fenton-type hydroxyl radical formation
    • Ito K, Yamamoto K, Kawanishi S (1992) Manganese-mediated oxidative damage of cellular and isolated DNA by isoniazid and related hydrazines: Non-Fenton-type hydroxyl radical formation. Biochemistry 31:11606-11613
    • (1992) Biochemistry , vol.31 , pp. 11606-11613
    • Ito, K.1    Yamamoto, K.2    Kawanishi, S.3
  • 54
    • 0025812765 scopus 로고
    • Interplay of cell wall barrier and beta-lactamase activity determines high resistance to beta-lactam antibiotics in mycobacterium chelonae
    • Jarlier V, Gutmann L, Nikaido H (1991) Interplay of cell wall barrier and beta-lactamase activity determines high resistance to beta-lactam antibiotics in mycobacterium chelonae. Antimicrob Agents Chemother 35:1937-1939
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 1937-1939
    • Jarlier, V.1    Gutmann, L.2    Nikaido, H.3
  • 55
    • 33746106088 scopus 로고    scopus 로고
    • Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs
    • Johansen SK, Maus CE, Plikaytis BB, Douthwaite S (2006) Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Mol Cell 23:173-182
    • (2006) Mol Cell , vol.23 , pp. 173-182
    • Johansen, S.K.1    Maus, C.E.2    Plikaytis, B.B.3    Douthwaite, S.4
  • 56
    • 0342867629 scopus 로고
    • Mycobacterial beta-lactamases
    • Hamilton-Miller JMT, Smith JT (eds Academic Press, London
    • Kasik JE (1979) Mycobacterial Beta-Lactamases. In: Hamilton-Miller JMT, Smith JT (eds) Beta-Lactamases. Academic Press, London, p 500
    • (1979) Beta-Lactamases , pp. 500
    • Kasik, J.E.1
  • 57
    • 0000603112 scopus 로고
    • Properties of beta-lactamases produced by three species of mycobacteria
    • Kasik JE, Peacham L (1968) Properties of beta-lactamases produced by three species of mycobacteria. Biochem J 107:675-682
    • (1968) Biochem J , vol.107 , pp. 675-682
    • Kasik, J.E.1    Peacham, L.2
  • 58
    • 53849117142 scopus 로고    scopus 로고
    • Biology of trans-translation
    • Keiler KC (2008) Biology of trans-translation. Annual Rev Microbiol 62:133-151
    • (2008) Annual Rev Microbiol , vol.62 , pp. 133-151
    • Keiler, K.C.1
  • 59
    • 84855195248 scopus 로고    scopus 로고
    • Characterization and transcriptome analysis of mycobacterium tuberculosis persisters
    • Keren I, Minami S, Rubin E, Lewis K (2011) Characterization and transcriptome analysis of mycobacterium tuberculosis persisters. mBio 2:e00100-00111
    • (2011) Mbio , vol.2
    • Keren, I.1    Minami, S.2    Rubin, E.3    Lewis, K.4
  • 60
    • 10044266575 scopus 로고    scopus 로고
    • Specialized persister cells and the mechanism of multidrug tolerance in escherichia coli
    • Keren I, Shah D, Spoering A, Kaldalu N, Lewis K (2004) Specialized persister cells and the mechanism of multidrug tolerance in escherichia coli. J Bacteriol 186:8172-8180
    • (2004) J Bacteriol , vol.186 , pp. 8172-8180
    • Keren, I.1    Shah, D.2    Spoering, A.3    Kaldalu, N.4    Lewis, K.5
  • 61
    • 75949092532 scopus 로고    scopus 로고
    • Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis
    • Kohanski MA, DePristo MA, Collins JJ (2010a) Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Mol Cell 37:311-320
    • (2010) Mol Cell , vol.37 , pp. 311-320
    • Kohanski, M.A.1    DePristo, M.A.2    Collins, J.J.3
  • 62
    • 77952884274 scopus 로고    scopus 로고
    • How antibiotics kill bacteria: From targets to networks
    • Kohanski MA, Dwyer DJ, Collins JJ (2010b) How antibiotics kill bacteria: From targets to networks. Nat Rev Microbiol 8:423-435
    • (2010) Nat Rev Microbiol , vol.8 , pp. 423-435
    • Kohanski, M.A.1    Dwyer, D.J.2    Collins, J.J.3
  • 63
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ (2007) A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130:797-810
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1    Dwyer, D.J.2    Hayete, B.3    Lawrence, C.A.4    Collins, J.J.5
  • 64
    • 45549104015 scopus 로고    scopus 로고
    • Multidrug tolerance of biofilms and persister cells
    • Lewis K (2008) Multidrug tolerance of biofilms and persister cells. Curr Top Microbiol Immunol 322:107-131
    • (2008) Curr Top Microbiol Immunol , vol.322 , pp. 107-131
    • Lewis, K.1
  • 65
    • 34250218203 scopus 로고    scopus 로고
    • PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in escherichia coli
    • Li Y, Zhang Y (2007) PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in escherichia coli. Antimicrobial Agents Chemother 51:2092-2099
    • (2007) Antimicrobial Agents Chemother , vol.51 , pp. 2092-2099
    • Li, Y.1    Zhang, Y.2
  • 66
    • 0033616584 scopus 로고    scopus 로고
    • A mutant of mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates
    • Liu J, Nikaido H (1999) A mutant of mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates. Proc Natl Acad Sci U S A 96:4011-4016
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4011-4016
    • Liu, J.1    Nikaido, H.2
  • 67
    • 0028820791 scopus 로고
    • Fluidity of the lipid domain of cell wall from mycobacterium chelonae
    • Liu J, Rosenberg EY, Nikaido H (1995) Fluidity of the lipid domain of cell wall from mycobacterium chelonae. Proc Natl Acad Sci USA 92:11254-11258
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11254-11258
    • Liu, J.1    Rosenberg, E.Y.2    Nikaido, H.3
  • 69
    • 12944255782 scopus 로고    scopus 로고
    • Mutation of tlya confers capreomycin resistance in mycobacterium tuberculosis
    • Maus CE, Plikaytis BB, Shinnick TM (2005) Mutation of tlyA confers capreomycin resistance in mycobacterium tuberculosis. Antimicrobial Agents Chemother 49:571-577
    • (2005) Antimicrobial Agents Chemother , vol.49 , pp. 571-577
    • Maus, C.E.1    Plikaytis, B.B.2    Shinnick, T.M.3
  • 70
    • 84960961533 scopus 로고
    • The fate of mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug
    • McCune RM Jr, McDermott W, Tompsett R (1956) The fate of mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug. J Exp Med 104:763-802
    • (1956) J Exp Med , vol.104 , pp. 763-802
    • McCune Jr., R.M.1    McDermott, W.2    Tompsett, R.3
  • 71
    • 0000164959 scopus 로고
    • Fate of mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique I the persistence of drug-susceptible tubercle bacilli in the tissues despite prolonged antimicrobial therapy
    • McCune RM Jr, Tompsett R (1956) Fate of mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. I. The persistence of drug-susceptible tubercle bacilli in the tissues despite prolonged antimicrobial therapy. J Exp Med 104:737-762
    • (1956) J Exp Med , vol.104 , pp. 737-762
    • McCune Jr., R.M.1    Tompsett, R.2
  • 72
    • 84861210848 scopus 로고    scopus 로고
    • A vapbc toxin-antitoxin module is a posttranscriptional regulator of metabolic flux in mycobacteria
    • McKenzie JL, Robson J, Berney M et al (2012) A VapBC toxin-antitoxin module is a posttranscriptional regulator of metabolic flux in mycobacteria. J Bacteriol 194:2189-2204
    • (2012) J Bacteriol , vol.194 , pp. 2189-2204
    • McKenzie, J.L.1    Robson, J.2    Berney, M.3
  • 73
    • 0033065469 scopus 로고    scopus 로고
    • Exposure to antibiotics induces expression of the mycobacterium tuberculosis sigF gene: Implications for chemotherapy against mycobacterial persistors
    • Michele TM, Ko C, Bishai WR (1999) Exposure to antibiotics induces expression of the mycobacterium tuberculosis sigF gene: Implications for chemotherapy against mycobacterial persistors. Antimicrobial Agents Chemother 43:218-225
    • (1999) Antimicrobial Agents Chemother , vol.43 , pp. 218-225
    • Michele, T.M.1    Ko, C.2    Bishai, W.R.3
  • 74
    • 0035180104 scopus 로고    scopus 로고
    • Intrinsic resistance of mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpA
    • Montero C, Mateu G, Rodriguez R, Takiff H (2001) Intrinsic resistance of mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpA. Antimicrob Agents Chemother 45:3387-3392
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 3387-3392
    • Montero, C.1    Mateu, G.2    Rodriguez, R.3    Takiff, H.4
  • 76
    • 24744436623 scopus 로고    scopus 로고
    • Ancestral antibiotic resistance in mycobacterium tuberculosis
    • Morris RP, Nguyen L, Gatfield J et al (2005) Ancestral antibiotic resistance in mycobacterium tuberculosis. Proc Natl Acad Sci USA 102:12200-12205
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12200-12205
    • Morris, R.P.1    Nguyen, L.2    Gatfield, J.3
  • 77
    • 67650761469 scopus 로고
    • Can tuberculosis be eradicated?
    • Myers A (1963) Can tuberculosis be eradicated? Chest 43:327-329
    • (1963) Chest , vol.43 , pp. 327-329
    • Myers, A.1
  • 78
    • 44849124472 scopus 로고    scopus 로고
    • Molecular cloning, overexpression and biochemical characterization of hypothetical betalactamases of mycobacterium tuberculosis H37Rv
    • Nampoothiri KM, Rubex R, Patel AK, Narayanan SS, Krishna S, Das SM, Pandey A (2008) Molecular cloning, overexpression and biochemical characterization of hypothetical betalactamases of mycobacterium tuberculosis H37Rv. J Appl Microbiol 105:59-67
    • (2008) J Appl Microbiol , vol.105 , pp. 59-67
    • Nampoothiri, K.M.1    Rubex, R.2    Patel, A.K.3    Narayanan, S.S.4    Krishna, S.5    Das, S.M.6    Pandey, A.7
  • 79
    • 0141960052 scopus 로고    scopus 로고
    • Intrinsic macrolide resistance in mycobacterium smegmatis is conferred by a novel erm gene, erm(38
    • Nash KA (2003) Intrinsic macrolide resistance in mycobacterium smegmatis is conferred by a novel erm gene, erm(38). Antimicrob Agents Chemother 47:3053-3060
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 3053-3060
    • Nash, K.A.1
  • 80
    • 14744302956 scopus 로고    scopus 로고
    • Molecular basis of intrinsic macrolide resistance in clinical isolates of mycobacterium fortuitum
    • Nash KA, Zhang Y, Brown-Elliott BA, Wallace RJ Jr (2005) Molecular basis of intrinsic macrolide resistance in clinical isolates of mycobacterium fortuitum. J Antimicrob Chemother 55:170-177
    • (2005) J Antimicrob Chemother , vol.55 , pp. 170-177
    • Nash, K.A.1    Zhang, Y.2    Brown-Elliott, B.A.3    Wallace Jr., R.J.4
  • 81
    • 84868145984 scopus 로고    scopus 로고
    • Targeting antibiotic resistance mechanisms in mycobacterium tuberculosis: Recharging the old magic bullets
    • Nguyen L (2012) Targeting antibiotic resistance mechanisms in mycobacterium tuberculosis: Recharging the old magic bullets. Expert Rev Anti Infect Ther 10:963-965
    • (2012) Expert Rev Anti Infect Ther , vol.10 , pp. 963-965
    • Nguyen, L.1
  • 82
    • 25144446168 scopus 로고    scopus 로고
    • FbpA-Dependent biosynthesis of trehalose dimycolate is required for the intrinsic multidrug resistance, cell wall structure, and colonial morphology of mycobacterium smegmatis
    • Nguyen L, Chinnapapagari S, Thompson CJ (2005) FbpA-Dependent biosynthesis of trehalose dimycolate is required for the intrinsic multidrug resistance, cell wall structure, and colonial morphology of mycobacterium smegmatis. J Bacteriol 187:6603-6611
    • (2005) J Bacteriol , vol.187 , pp. 6603-6611
    • Nguyen, L.1    Chinnapapagari, S.2    Thompson, C.J.3
  • 83
    • 65249188733 scopus 로고    scopus 로고
    • Mycobacterial subversion of chemotherapeutic reagents and host defense tactics: Challenges in tuberculosis drug development
    • Nguyen L, Pieters J (2009) Mycobacterial subversion of chemotherapeutic reagents and host defense tactics: Challenges in tuberculosis drug development. Ann Rev Pharmacol Toxicol 49:427-453
    • (2009) Ann Rev Pharmacol Toxicol , vol.49 , pp. 427-453
    • Nguyen, L.1    Pieters, J.2
  • 84
    • 33744950488 scopus 로고    scopus 로고
    • Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the odhi protein
    • Niebisch A, Kabus A, Schultz C, Weil B, Bott M (2006) Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein. J Biol Chem 281:12300-12307
    • (2006) J Biol Chem , vol.281 , pp. 12300-12307
    • Niebisch, A.1    Kabus, A.2    Schultz, C.3    Weil, B.4    Bott, M.5
  • 85
    • 0141677886 scopus 로고    scopus 로고
    • Mycobacterial porins-new channel proteins in unique outer membranes
    • Niederweis M (2003) Mycobacterial porins-new channel proteins in unique outer membranes. Mol Microbiol 49:1167-1177
    • (2003) Mol Microbiol , vol.49 , pp. 1167-1177
    • Niederweis, M.1
  • 86
    • 23444456920 scopus 로고
    • Prevention of drug access to bacterial targets: Permeability barriers and active efflux
    • Nikaido H (1994) Prevention of drug access to bacterial targets: Permeability barriers and active efflux. Science 264:382-388
    • (1994) Science , vol.264 , pp. 382-388
    • Nikaido, H.1
  • 87
    • 0034817367 scopus 로고    scopus 로고
    • Analysis of a complete library of putative drug transporter genes in escherichia coli
    • Nishino K, Yamaguchi A (2001) Analysis of a complete library of putative drug transporter genes in escherichia coli. J Bacteriol 183:5803-5812
    • (2001) J Bacteriol , vol.183 , pp. 5803-5812
    • Nishino, K.1    Yamaguchi, A.2
  • 88
    • 66149097000 scopus 로고    scopus 로고
    • An intramolecular switch regulates phosphoindependent FHA domain interactions in mycobacterium tuberculosis
    • :ra12
    • Nott TJ, Kelly G, Stach L, et al (2009) An intramolecular switch regulates phosphoindependent FHA domain interactions in mycobacterium tuberculosis. Science Signal 2:ra12
    • (2009) Science Signal , vol.2
    • Nott, T.J.1    Kelly, G.2    Stach, L.3
  • 89
    • 29644447018 scopus 로고    scopus 로고
    • Multidrug-resistant tuberculosis (MDR-TB): Epidemiology, prevention and treatment
    • Ormerod LP (2005) Multidrug-resistant tuberculosis (MDR-TB): Epidemiology, prevention and treatment. Br Med Bull 73-74:17-24
    • (2005) Br Med Bull , vol.73-74 , pp. 17-24
    • Ormerod, L.P.1
  • 91
    • 0030956230 scopus 로고    scopus 로고
    • Contribution of beta-lactamase production to the resistance of mycobacteria to beta-lactam antibiotics
    • Quinting B, Reyrat JM, Monnaie D et al (1997) Contribution of beta-lactamase production to the resistance of mycobacteria to beta-lactam antibiotics. FEBS Lett 406:275-278
    • (1997) FEBS Lett , vol.406 , pp. 275-278
    • Quinting, B.1    Reyrat, J.M.2    Monnaie, D.3
  • 92
    • 0036840388 scopus 로고    scopus 로고
    • Mycothiol-deficient mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics
    • Rawat M, Newton GL, Ko M, Martinez GJ, Fahey RC, Av-Gay Y (2002) Mycothiol-deficient mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics. Antimicrob Agents Chemother 46:3348-3355
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3348-3355
    • Rawat, M.1    Newton, G.L.2    Ko, M.3    Martinez, G.J.4    Fahey, R.C.5    Av-Gay, Y.6
  • 93
    • 0034537725 scopus 로고    scopus 로고
    • Compensatory evolution in rifampin-resistant escherichia coli
    • Reynolds MG (2000) Compensatory evolution in rifampin-resistant escherichia coli. Genetics 156:1471-1481
    • (2000) Genetics , vol.156 , pp. 1471-1481
    • Reynolds, M.G.1
  • 96
    • 0032794697 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis: Variations on the cornell murine model
    • Scanga CA, Mohan VP, Joseph H, Yu K, Chan J, Flynn JL (1999) Reactivation of latent tuberculosis: Variations on the cornell murine model. Infect Immun 67:4531-4538
    • (1999) Infect Immun , vol.67 , pp. 4531-4538
    • Scanga, C.A.1    Mohan, V.P.2    Joseph, H.3    Yu, K.4    Chan, J.5    Flynn, J.L.6
  • 98
    • 0029954860 scopus 로고    scopus 로고
    • Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus
    • Scorpio A, Zhang Y (1996) Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus. Nat Med 2:662-667
    • (1996) Nat Med , vol.2 , pp. 662-667
    • Scorpio, A.1    Zhang, Y.2
  • 99
  • 100
    • 84861474432 scopus 로고    scopus 로고
    • Modeling the dynamic relationship between HIV and the risk of drug-resistant tuberculosis
    • 135ra167
    • Sergeev R, Colijn C, Murray M, Cohen T (2012) Modeling the dynamic relationship between HIV and the risk of drug-resistant tuberculosis. Sci Transl Med 4:135ra167
    • (2012) Sci Transl Med , vol.4
    • Sergeev, R.1    Colijn, C.2    Murray, M.3    Cohen, T.4
  • 101
    • 84859783727 scopus 로고    scopus 로고
    • Growth and translation inhibition through sequence-specific rna binding by mycobacterium tuberculosis vapc toxin
    • Sharp JD, Cruz JW, Raman S, Inouye M, Husson RN, Woychik NA (2012) Growth and translation inhibition through sequence-specific RNA binding by mycobacterium tuberculosis VapC toxin. J Biol Chem 287:12835-12847
    • (2012) J Biol Chem , vol.287 , pp. 12835-12847
    • Sharp, J.D.1    Cruz, J.W.2    Raman, S.3    Inouye, M.4    Husson, R.N.5    Woychik, N.A.6
  • 103
    • 27344432975 scopus 로고    scopus 로고
    • Changes in energy metabolism of mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration
    • Shi L, Sohaskey CD, Kana BD, Dawes S, North RJ, Mizrahi V, Gennaro ML (2005) Changes in energy metabolism of mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration. Proc Natl Acad Sci USA 102:15629-15634
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15629-15634
    • Shi, L.1    Sohaskey, C.D.2    Kana, B.D.3    Dawes, S.4    North, R.J.5    Mizrahi, V.6    Gennaro, M.L.7
  • 104
    • 81155160151 scopus 로고    scopus 로고
    • Pyrazinamide inhibits trans-translation in mycobacterium tuberculosis
    • Shi W, Zhang X, Jiang X et al (2011) Pyrazinamide inhibits trans-translation in mycobacterium tuberculosis. Science 333:1630-1632
    • (2011) Science , vol.333 , pp. 1630-1632
    • Shi, W.1    Zhang, X.2    Jiang, X.3
  • 105
    • 77953522110 scopus 로고    scopus 로고
    • PhoY2 but not PhoY1 is the PhoU homologue involved in persisters in mycobacterium tuberculosis
    • Shi W, Zhang Y (2010) PhoY2 but not PhoY1 is the PhoU homologue involved in persisters in mycobacterium tuberculosis. J Antimicrob Chemother 65:1237-1242
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1237-1242
    • Shi, W.1    Zhang, Y.2
  • 106
    • 12644263413 scopus 로고    scopus 로고
    • Inorganic polyphosphate and the induction of rpoS expression
    • Shiba T, Tsutsumi K, Yano H et al (1997) Inorganic polyphosphate and the induction of rpoS expression. Proc Natl Acad Sci USA 94:11210-11215
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11210-11215
    • Shiba, T.1    Tsutsumi, K.2    Yano, H.3
  • 107
    • 20444454266 scopus 로고    scopus 로고
    • Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of mycobacterium tuberculosis in the spleens of guinea pigs
    • Singh A, Gupta R, Vishwakarma RA, Narayanan PR, Paramasivan CN, Ramanathan VD, Tyagi AK (2005) Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of mycobacterium tuberculosis in the spleens of guinea pigs. J Bacteriol 187:4173-4186
    • (2005) J Bacteriol , vol.187 , pp. 4173-4186
    • Singh, A.1    Gupta, R.2    Vishwakarma, R.A.3    Narayanan, P.R.4    Paramasivan, C.N.5    Ramanathan, V.D.6    Tyagi, A.K.7
  • 108
    • 1542648514 scopus 로고    scopus 로고
    • MymA operon of mycobacterium tuberculosis: Its regulation and importance in the cell envelope
    • Singh A, Jain S, Gupta S, Das T, Tyagi AK (2003) mymA operon of mycobacterium tuberculosis: Its regulation and importance in the cell envelope. FEMS Microbiol Lett 227:53-63
    • (2003) FEMS Microbiol Lett , vol.227 , pp. 53-63
    • Singh, A.1    Jain, S.2    Gupta, S.3    Das, T.4    Tyagi, A.K.5
  • 109
    • 49649125176 scopus 로고    scopus 로고
    • Rv1698 of mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteins
    • Siroy A, Mailaender C, Harder D et al (2008) Rv1698 of mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteins. J Biol Chem 283:17827-17837
    • (2008) J Biol Chem , vol.283 , pp. 17827-17837
    • Siroy, A.1    Mailaender, C.2    Harder, D.3
  • 111
    • 81455127376 scopus 로고    scopus 로고
    • The role of the novel exopolyphosphatase MT0516 in mycobacterium tuberculosis drug tolerance and persistence
    • Thayil SM, Morrison N, Schechter N, Rubin H, Karakousis PC (2011) The role of the novel exopolyphosphatase MT0516 in mycobacterium tuberculosis drug tolerance and persistence. PloS one 6:e28076
    • (2011) PloS one , vol.6
    • Thayil, S.M.1    Morrison, N.2    Schechter, N.3    Rubin, H.4    Karakousis, P.C.5
  • 112
    • 22644447865 scopus 로고    scopus 로고
    • Variant tricarboxylic acid cycle in mycobacterium tuberculosis: Identification of alpha-ketoglutarate decarboxylase
    • Tian J, Bryk R, Itoh M, Suematsu M, Nathan C (2005) Variant tricarboxylic acid cycle in mycobacterium tuberculosis: Identification of alpha-ketoglutarate decarboxylase. Proc Natl Acad Sci USA 102:10670-10675
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10670-10675
    • Tian, J.1    Bryk, R.2    Itoh, M.3    Suematsu, M.4    Nathan, C.5
  • 113
    • 77951676093 scopus 로고    scopus 로고
    • Biochemical and structural characterization of mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem
    • Tremblay LW, Fan F, Blanchard JS (2010) Biochemical and structural characterization of mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. Biochemistry 49:3766-3773
    • (2010) Biochemistry , vol.49 , pp. 3766-3773
    • Tremblay, L.W.1    Fan, F.2    Blanchard, J.S.3
  • 114
    • 84858765120 scopus 로고    scopus 로고
    • MDR XDR TDR tuberculosis: Ominous progression
    • Udwadia ZF (2012) MDR, XDR, TDR tuberculosis: Ominous progression. Thorax 67:286-288
    • (2012) Thorax , vol.67 , pp. 286-288
    • Udwadia, Z.F.1
  • 115
    • 0038203147 scopus 로고    scopus 로고
    • What can structure tell us about in vivo function? the case of aminoglycoside-resistance genes
    • Vetting M, Roderick SL, Hegde S, Magnet S, Blanchard JS (2003) What can structure tell us about in vivo function? The case of aminoglycoside-resistance genes. Biochem Soc Trans 31:520-522
    • (2003) Biochem Soc Trans , vol.31 , pp. 520-522
    • Vetting, M.1    Roderick, S.L.2    Hegde, S.3    Magnet, S.4    Blanchard, J.S.5
  • 116
    • 49249132882 scopus 로고    scopus 로고
    • Mycothiol biosynthesis is essential for ethionamide susceptibility in mycobacterium tuberculosis
    • Vilcheze C, Av-Gay Y, Attarian R et al (2008) Mycothiol biosynthesis is essential for ethionamide susceptibility in mycobacterium tuberculosis. Molec Microbiol 69:1316-1329
    • (2008) Molec Microbiol , vol.69 , pp. 1316-1329
    • Vilcheze, C.1    Av-Gay, Y.2    Attarian, R.3
  • 119
    • 2942718724 scopus 로고    scopus 로고
    • Protein kinase G from pathogenic mycobacteria promotes survival within macrophages
    • Walburger A, Koul A, Ferrari G et al (2004) Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science 304:1800-1804
    • (2004) Science , vol.304 , pp. 1800-1804
    • Walburger, A.1    Koul, A.2    Ferrari, G.3
  • 121
    • 33746878510 scopus 로고    scopus 로고
    • Crystal structure and activity studies of the mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics
    • Wang F, Cassidy C, Sacchettini JC (2006) Crystal structure and activity studies of the mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics. Antimicrob Agents Chemother 50:2762-2771
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2762-2771
    • Wang, F.1    Cassidy, C.2    Sacchettini, J.C.3
  • 122
    • 0031942624 scopus 로고    scopus 로고
    • Role of superoxide in catalase-peroxidase-mediated isoniazid action against mycobacteria
    • Wang JY, Burger RM, Drlica K (1998) Role of superoxide in catalase-peroxidase-mediated isoniazid action against mycobacteria. Antimicrobial Agents Chemother 42:709-711
    • (1998) Antimicrobial Agents Chemother , vol.42 , pp. 709-711
    • Wang, J.Y.1    Burger, R.M.2    Drlica, K.3
  • 123
    • 84862523150 scopus 로고    scopus 로고
    • Specific inactivation of two immunomodulatory siglec genes during human evolution
    • Wang X, Mitra N, Secundino I et al (2012) Specific inactivation of two immunomodulatory SIGLEC genes during human evolution. Proc Natl Acad Sci USA 109:9935-9940
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 9935-9940
    • Wang, X.1    Mitra, N.2    Secundino, I.3
  • 124
    • 0026694328 scopus 로고
    • In vitro activity of meropenem and imipenem against mycobacteria: Development of a daily antibiotic dosing schedule
    • Watt B, Edwards JR, Rayner A, Grindey AJ, Harris G (1992) In vitro activity of meropenem and imipenem against mycobacteria: Development of a daily antibiotic dosing schedule. Tuber Lung Dis 73:134-136
    • (1992) Tuber Lung Dis , vol.73 , pp. 134-136
    • Watt, B.1    Edwards, J.R.2    Rayner, A.3    Grindey, A.J.4    Harris, G.5
  • 125
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne LG, Hayes LG (1996) An in vitro model for sequential study of shiftdown of mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect Immun 64:2062-2069
    • (1996) Infect Immun , vol.64 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 126
    • 0033988815 scopus 로고    scopus 로고
    • Identification of a Mycobacterium tuberculosis gene that enhances mycobacterial survival in macrophages
    • Wei J, Dahl JL, Moulder JW, Roberts EA, O'Gaora P, Young DB, Friedman RL (2000) Identification of a Mycobacterium tuberculosis gene that enhances mycobacterial survival in macrophages. J Bacteriol 182:377-384
    • (2000) J Bacteriol , vol.182 , pp. 377-384
    • Wei, J.1    Dahl, J.L.2    Moulder, J.W.3    Roberts, E.A.4    O'Gaora, P.5    Young, D.B.6    Friedman, R.L.7
  • 128
    • 0034423519 scopus 로고    scopus 로고
    • Binding and cross-linking of tmRNA to ribosomal protein S1, on and off the escherichia coli ribosome
    • Wower IK, Zwieb CW, Guven SA, Wower J (2000) Binding and cross-linking of tmRNA to ribosomal protein S1, on and off the escherichia coli ribosome. EMBO J 19:6612-6621
    • (2000) EMBO J , vol.19 , pp. 6612-6621
    • Wower, I.K.1    Zwieb, C.W.2    Guven, S.A.3    Wower, J.4
  • 129
    • 27644588268 scopus 로고    scopus 로고
    • Differential antibiotic susceptibilities of starved mycobacterium tuberculosis isolates
    • Xie Z, Siddiqi N, Rubin EJ (2005) Differential antibiotic susceptibilities of starved mycobacterium tuberculosis isolates. Antimicrobial Agents Chemother 49:4778-4780
    • (2005) Antimicrobial Agents Chemother , vol.49 , pp. 4778-4780
    • Xie, Z.1    Siddiqi, N.2    Rubin, E.J.3
  • 130
    • 73949102884 scopus 로고    scopus 로고
    • Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in mycobacterium tuberculosis
    • Zaunbrecher MA, Sikes RD Jr, Metchock B, Shinnick TM, Posey JE (2009) Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in mycobacterium tuberculosis. Proc Natl Acad Sci USA 106:20004-20009
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20004-20009
    • Zaunbrecher, M.A.1    Sikes Jr., R.D.2    Metchock, B.3    Shinnick, T.M.4    Posey, J.E.5
  • 131
    • 84949176628 scopus 로고    scopus 로고
    • Drug resistant and persistent tuberculosis: Mechanisms and drug development
    • Dougherty TJ, Pucci MJ (ed Springer Science ? Business Media
    • Zhang Y (2012) Drug resistant and persistent tuberculosis: Mechanisms and drug development. In: Dougherty TJ, Pucci MJ (ed) Antibiotic discovery and development. Springer Science ? Business Media, pp 719-746
    • (2012) Antibiotic Discovery And Development , pp. 719-746
    • Zhang, Y.1
  • 132
    • 0029830769 scopus 로고    scopus 로고
    • Molecular basis for the exquisite sensitivity of mycobacterium tuberculosis to isoniazid
    • Zhang Y, Dhandayuthapani S, Deretic V (1996) Molecular basis for the exquisite sensitivity of mycobacterium tuberculosis to isoniazid. Proc Natl Acad Sci USA 93:13212-13216
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13212-13216
    • Zhang, Y.1    Dhandayuthapani, S.2    Deretic, V.3
  • 133
    • 0026705772 scopus 로고
    • The catalase-peroxidase gene and isoniazid resistance of mycobacterium tuberculosis
    • Zhang Y, Heym B, Allen B, Young D, Cole S (1992) The catalase-peroxidase gene and isoniazid resistance of mycobacterium tuberculosis. Nature 358:591-593
    • (1992) Nature , vol.358 , pp. 591-593
    • Zhang, Y.1    Heym, B.2    Allen, B.3    Young, D.4    Cole, S.5
  • 134
    • 49449107199 scopus 로고    scopus 로고
    • Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state
    • Zuber B, Chami M, Houssin C, Dubochet J, Griffiths G, Daffe M (2008) Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state. J Bacteriol 190:5672-5680
    • (2008) J Bacteriol , vol.190 , pp. 5672-5680
    • Zuber, B.1    Chami, M.2    Houssin, C.3    Dubochet, J.4    Griffiths, G.5    Daffe, M.6


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