-
1
-
-
0033040998
-
Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus
-
Aeschlimann JR, Dresser LD, Kaatz GW & Rybak MJ (1999) Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus. Antimicrob Agents Ch43: 335-340.
-
(1999)
Antimicrob Agents Ch
, vol.43
, pp. 335-340
-
-
Aeschlimann, J.R.1
Dresser, L.D.2
Kaatz, G.W.3
Rybak, M.J.4
-
2
-
-
0031793411
-
Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis
-
Aínsa JA, Blokpoel MC, Otal I, Young DB, De Smet KA & Martín C (1998) Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis. J Bacteriol180: 5836-5843.
-
(1998)
J Bacteriol
, vol.180
, pp. 5836-5843
-
-
Aínsa, J.A.1
Blokpoel, M.C.2
Otal, I.3
Young, D.B.4
De Smet, K.A.5
Martín, C.6
-
3
-
-
52449123326
-
Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps
-
Amaral L, Martins M, Viveiros M, Molnar J & Kristiansen JE (2008) Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps. Curr Drug Targets9: 816-819.
-
(2008)
Curr Drug Targets
, vol.9
, pp. 816-819
-
-
Amaral, L.1
Martins, M.2
Viveiros, M.3
Molnar, J.4
Kristiansen, J.E.5
-
4
-
-
0026662530
-
Partial purification and reconstitution of the human multidrug-resistance pump
-
P Natl Acad Sci USA
-
Ambudkar SV, Lelong IH, Zhang J, Cardarelli CO, Gottesman MM & Pastan I (1992) Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis. P Natl Acad Sci USA 89: 8472-8476.
-
(1992)
characterization of the drug-stimulatable ATP hydrolysis
, vol.89
, pp. 8472-8476
-
-
Ambudkar, S.V.1
Lelong, I.H.2
Zhang, J.3
Cardarelli, C.O.4
Gottesman, M.M.5
Pastan, I.6
-
5
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA & Cardarelli C (1999) Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol39: 361-398.
-
(1999)
Annu Rev Pharmacol
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Cardarelli, C.4
-
6
-
-
78649642212
-
Rv1218c, an ABC Transporter of Mycobacterium tuberculosis with Implications in Drug Discovery
-
Balganesh M, Kuruppath S, Marcel N, Sharma S, Nair A & Sharma U (2010) Rv1218c, an ABC Transporter of Mycobacterium tuberculosis with Implications in Drug Discovery. Antimicrob Agents Ch54: 5167-5172.
-
(2010)
Antimicrob Agents Ch
, vol.54
, pp. 5167-5172
-
-
Balganesh, M.1
Kuruppath, S.2
Marcel, N.3
Sharma, S.4
Nair, A.5
Sharma, U.6
-
7
-
-
72449161765
-
Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator
-
Bellinzoni M, Buroni S, Schaeffer F, Riccardi G, De Rossi E & Alzari PM (2009) Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator. J Bacteriol191: 7531-7537.
-
(2009)
J Bacteriol
, vol.191
, pp. 7531-7537
-
-
Bellinzoni, M.1
Buroni, S.2
Schaeffer, F.3
Riccardi, G.4
De Rossi, E.5
Alzari, P.M.6
-
8
-
-
10744228817
-
The knockout of the lprG-Rv1410 operon produces strong attenuation of Mycobacterium tuberculosis
-
Bigi F, Gioffre A, Klepp Let al. (2004) The knockout of the lprG-Rv1410 operon produces strong attenuation of Mycobacterium tuberculosis. Microbes Infect6: 182-187.
-
(2004)
Microbes Infect
, vol.6
, pp. 182-187
-
-
Bigi, F.1
Gioffre, A.2
Klepp, L.3
-
9
-
-
57649181740
-
Effect of the efflux inhibitors 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide on antimicrobial susceptibility and virulence factor production in Vibrio cholerae
-
Bina XR, Philippart JA & Bina JE (2009) Effect of the efflux inhibitors 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide on antimicrobial susceptibility and virulence factor production in Vibrio cholerae. J Antimicrob Chemoth63: 103-108.
-
(2009)
J Antimicrob Chemoth
, vol.63
, pp. 103-108
-
-
Bina, X.R.1
Philippart, J.A.2
Bina, J.E.3
-
10
-
-
85044709164
-
Management of extensively drug-resistant tuberculosis in Peru
-
PLoS One
-
Bonilla CA, Crossa A, Jave HOet al. (2008) Management of extensively drug-resistant tuberculosis in Peru: cure is possible. PLoS One 3: e2957.
-
(2008)
cure is possible
, vol.3
-
-
Bonilla, C.A.1
Crossa, A.2
Jave, H.O.3
-
12
-
-
0033819143
-
The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis
-
Braibant M, Gilot P & Content J (2000) The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis. FEMS Microbiol Rev24: 449-467.
-
(2000)
FEMS Microbiol Rev
, vol.24
, pp. 449-467
-
-
Braibant, M.1
Gilot, P.2
Content, J.3
-
13
-
-
33845277546
-
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis
-
Buroni S, Manina G, Guglierame P, Pasca MR, Riccardi G & De Rossi E (2006) LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. Antimicrob Agents Ch50: 4044-4052.
-
(2006)
Antimicrob Agents Ch
, vol.50
, pp. 4044-4052
-
-
Buroni, S.1
Manina, G.2
Guglierame, P.3
Pasca, M.R.4
Riccardi, G.5
De Rossi, E.6
-
14
-
-
11144235253
-
Efflux-mediated antibiotics resistance in bacteria
-
Cattoir V (2004) Efflux-mediated antibiotics resistance in bacteria. Pathol Biol52: 607-616.
-
(2004)
Pathol Biol
, vol.52
, pp. 607-616
-
-
Cattoir, V.1
-
15
-
-
77950657864
-
Growth-related changes in intracellular spermidine and its effect on efflux pump expression and quorum sensing in Burkholderia pseudomallei
-
Chan YY & Chua KL (2010) Growth-related changes in intracellular spermidine and its effect on efflux pump expression and quorum sensing in Burkholderia pseudomallei. Microbiology156: 1144-1154.
-
(2010)
Microbiology
, vol.156
, pp. 1144-1154
-
-
Chan, Y.Y.1
Chua, K.L.2
-
16
-
-
0036796243
-
Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis
-
Choudhuri BS, Bhakta S, Barik R, Basu J, Kundu M & Chakrabarti P (2002) Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis. Biochem J367: 279-285.
-
(2002)
Biochem J
, vol.367
, pp. 279-285
-
-
Choudhuri, B.S.1
Bhakta, S.2
Barik, R.3
Basu, J.4
Kundu, M.5
Chakrabarti, P.6
-
18
-
-
20144387448
-
Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol
-
Colangeli R, Helb D, Sridharan Set al. (2005) Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol. Mol Microbiol55: 1829-1840.
-
(2005)
Mol Microbiol
, vol.55
, pp. 1829-1840
-
-
Colangeli, R.1
Helb, D.2
Sridharan, S.3
-
19
-
-
46249102682
-
Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis
-
Danilchanka O, Mailaender C & Niederweis M (2008) Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. Antimicrob Agents Ch52: 2503-2511.
-
(2008)
Antimicrob Agents Ch
, vol.52
, pp. 2503-2511
-
-
Danilchanka, O.1
Mailaender, C.2
Niederweis, M.3
-
20
-
-
0031950082
-
Molecular cloning and functional analysis of a novel tetracycline resistance determinant, tet(V), from Mycobacterium smegmatis
-
De Rossi E, Blokpoel MC, Cantoni R, Branzoni M, Riccardi G, Young DB, De Smet KA & Ciferri O (1998a) Molecular cloning and functional analysis of a novel tetracycline resistance determinant, tet(V), from Mycobacterium smegmatis. Antimicrob Agents Ch42: 1931-1937.
-
(1998)
Antimicrob Agents Ch
, vol.42
, pp. 1931-1937
-
-
De Rossi, E.1
Blokpoel, M.C.2
Cantoni, R.3
Branzoni, M.4
Riccardi, G.5
Young, D.B.6
De Smet, K.A.7
Ciferri, O.8
-
21
-
-
0031733415
-
mmr, a Mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors
-
De Rossi E, Branzoni M, Cantoni R, Milano A, Riccardi G & Ciferri O (1998b) mmr, a Mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors. J Bacteriol180: 6068-6071.
-
(1998)
J Bacteriol
, vol.180
, pp. 6068-6071
-
-
De Rossi, E.1
Branzoni, M.2
Cantoni, R.3
Milano, A.4
Riccardi, G.5
Ciferri, O.6
-
22
-
-
0345269084
-
The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis
-
De Rossi E, Arrigo P, Bellinzoni M, Silva PA, Martín C, Aínsa JA, Guglierame P & Riccardi G (2002) The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis. Mol Med8: 714-724.
-
(2002)
Mol Med
, vol.8
, pp. 714-724
-
-
De Rossi, E.1
Arrigo, P.2
Bellinzoni, M.3
Silva, P.A.4
Martín, C.5
Aínsa, J.A.6
Guglierame, P.7
Riccardi, G.8
-
23
-
-
33644900505
-
Role of mycobacterial efflux transporters in drug resistance
-
FEMS Microbiol Rev
-
De Rossi E, Ainsa JA & Riccardi G (2006) Role of mycobacterial efflux transporters in drug resistance: an unresolved question. FEMS Microbiol Rev 30: 36-52.
-
(2006)
an unresolved question
, vol.30
, pp. 36-52
-
-
De Rossi, E.1
Ainsa, J.A.2
Riccardi, G.3
-
24
-
-
58649094872
-
BacA, an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis
-
Domenech P, Kobayashi H, LeVier K, Walker GC & Barry CE (2009) BacA, an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis. J Bacteriol191: 477-485.
-
(2009)
J Bacteriol
, vol.191
, pp. 477-485
-
-
Domenech, P.1
Kobayashi, H.2
LeVier, K.3
Walker, G.C.4
Barry, C.E.5
-
25
-
-
77956319845
-
A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine
-
Dutta NK, Mehra S & Kaushal D (2010) A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. PLoS One5: e10069.
-
(2010)
PLoS One
, vol.5
-
-
Dutta, N.K.1
Mehra, S.2
Kaushal, D.3
-
26
-
-
57749116331
-
Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosis
-
Dye C (2009) Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosis. Nat Rev Microbiol7: 81-87.
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 81-87
-
-
Dye, C.1
-
27
-
-
36048965153
-
Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid
-
Escribano I, Rodriguez JC, Llorca B, García-Pachon E, Ruiz M & Royo G (2007) Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid. Chemotherapy53: 397-401.
-
(2007)
Chemotherapy
, vol.53
, pp. 397-401
-
-
Escribano, I.1
Rodriguez, J.C.2
Llorca, B.3
García-Pachon, E.4
Ruiz, M.5
Royo, G.6
-
28
-
-
39749168415
-
Function of a mycobacterial major facilitator superfamily pump requires a membrane-associated lipoprotein
-
Farrow MF & Rubin EJ (2008) Function of a mycobacterial major facilitator superfamily pump requires a membrane-associated lipoprotein. J Bacteriol190: 1783-1791.
-
(2008)
J Bacteriol
, vol.190
, pp. 1783-1791
-
-
Farrow, M.F.1
Rubin, E.J.2
-
29
-
-
69949100882
-
The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth
-
Fontán PA, Voskuil MI, Gomez M, Tan D, Pardini M, Manganelli R, Fattorini L, Schoolnik GK & Smith I (2009) The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth. J Bacteriol191: 5628-5633.
-
(2009)
J Bacteriol
, vol.191
, pp. 5628-5633
-
-
Fontán, P.A.1
Voskuil, M.I.2
Gomez, M.3
Tan, D.4
Pardini, M.5
Manganelli, R.6
Fattorini, L.7
Schoolnik, G.K.8
Smith, I.9
-
30
-
-
33750629139
-
Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa
-
Gandhi NR, Moll A, Sturm AW, Pawinski R, Govender T, Lalloo U, Zeller K, Andrews J & Friedland G (2006) Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet368: 1575-1580.
-
(2006)
Lancet
, vol.368
, pp. 1575-1580
-
-
Gandhi, N.R.1
Moll, A.2
Sturm, A.W.3
Pawinski, R.4
Govender, T.5
Lalloo, U.6
Zeller, K.7
Andrews, J.8
Friedland, G.9
-
31
-
-
33746904362
-
Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes
-
Geiman DE, Raghunand TR, Agarwal N & Bishai WR (2006) Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes. Antimicrob Agents Ch50: 2836-2841.
-
(2006)
Antimicrob Agents Ch
, vol.50
, pp. 2836-2841
-
-
Geiman, D.E.1
Raghunand, T.R.2
Agarwal, N.3
Bishai, W.R.4
-
32
-
-
0025999987
-
A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin
-
Guilfoile PG & Hutchinson CR (1991) A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin. P Natl Acad Sci USA88: 8553-8557.
-
(1991)
P Natl Acad Sci USA
, vol.88
, pp. 8553-8557
-
-
Guilfoile, P.G.1
Hutchinson, C.R.2
-
33
-
-
77949607221
-
Microarray analysis of efflux pump genes in multidrug-resistant Mycobacterium tuberculosis during stress induced by common anti-tuberculous drugs
-
Gupta AK, Katoch VM, Chauhan DS, Sharma R, Singh M, Venkatesan K & Sharma VD (2010a) Microarray analysis of efflux pump genes in multidrug-resistant Mycobacterium tuberculosis during stress induced by common anti-tuberculous drugs. Microb Drug Resist16: 21-28.
-
(2010)
Microb Drug Resist
, vol.16
, pp. 21-28
-
-
Gupta, A.K.1
Katoch, V.M.2
Chauhan, D.S.3
Sharma, R.4
Singh, M.5
Venkatesan, K.6
Sharma, V.D.7
-
34
-
-
77956068391
-
jefA (Rv2459), a drug efflux gene in Mycobacterium tuberculosis confers resistance to isoniazid & ethambutol
-
Gupta AK, Reddy VP, Lavania M, Chauhan DS, Venkatesan K, Sharma VD, Tyagi AK & Katoch VM (2010b) jefA (Rv2459), a drug efflux gene in Mycobacterium tuberculosis confers resistance to isoniazid & ethambutol. Indian J Med Res132: 176-188.
-
(2010)
Indian J Med Res
, vol.132
, pp. 176-188
-
-
Gupta, A.K.1
Reddy, V.P.2
Lavania, M.3
Chauhan, D.S.4
Venkatesan, K.5
Sharma, V.D.6
Tyagi, A.K.7
Katoch, V.M.8
-
35
-
-
78650181025
-
Pseudomonas aeruginosa biofilms in cystic fibrosis
-
Høiby N, Ciofu O & Bjarnsholt T (2010) Pseudomonas aeruginosa biofilms in cystic fibrosis. Future Microbiol5: 1663-1674.
-
(2010)
Future Microbiol
, vol.5
, pp. 1663-1674
-
-
Høiby, N.1
Ciofu, O.2
Bjarnsholt, T.3
-
37
-
-
41149120586
-
Assessment of efflux pump gene expression in a clinical isolate Mycobacterium tuberculosis by real-time reverse transcription PCR
-
Jiang X, Zhang W, Zhang Y, Gao F, Lu C, Zhang X & Wang H (2008) Assessment of efflux pump gene expression in a clinical isolate Mycobacterium tuberculosis by real-time reverse transcription PCR. Microb Drug Resist14: 7-11.
-
(2008)
Microb Drug Resist
, vol.14
, pp. 7-11
-
-
Jiang, X.1
Zhang, W.2
Zhang, Y.3
Gao, F.4
Lu, C.5
Zhang, X.6
Wang, H.7
-
39
-
-
15744392285
-
Bacterial efflux pump inhibition
-
Kaatz GW (2005) Bacterial efflux pump inhibition. Curr Opin Investig D6: 191-198.
-
(2005)
Curr Opin Investig D
, vol.6
, pp. 191-198
-
-
Kaatz, G.W.1
-
40
-
-
42449128654
-
Identification of novel metronidazole-inducible genes in Mycobacterium smegmatis using a customized amplification library
-
Kim SY, Shin SJ, Song CH, Jo EK, Kim HJ & Park JK (2008) Identification of novel metronidazole-inducible genes in Mycobacterium smegmatis using a customized amplification library. FEMS Microbiol Lett282: 282-289.
-
(2008)
FEMS Microbiol Lett
, vol.282
, pp. 282-289
-
-
Kim, S.Y.1
Shin, S.J.2
Song, C.H.3
Jo, E.K.4
Kim, H.J.5
Park, J.K.6
-
41
-
-
0032469004
-
Paradoxical enhancement of the activity of a bacterial multidrug transporter caused by substitutions of a conserved residue
-
Klyachko KA & Neyfakh AA (1998) Paradoxical enhancement of the activity of a bacterial multidrug transporter caused by substitutions of a conserved residue. J Bacteriol180: 2817-2821.
-
(1998)
J Bacteriol
, vol.180
, pp. 2817-2821
-
-
Klyachko, K.A.1
Neyfakh, A.A.2
-
42
-
-
0026588343
-
Active efflux mechanisms for antimicrobial resistance
-
Levy SB (1992) Active efflux mechanisms for antimicrobial resistance. Antimicrob Agents Ch36: 695-703.
-
(1992)
Antimicrob Agents Ch
, vol.36
, pp. 695-703
-
-
Levy, S.B.1
-
43
-
-
0442307441
-
Efflux-mediated drug resistance in bacteria
-
Li XZ & Nikaido H (2004) Efflux-mediated drug resistance in bacteria. Drugs64: 159-204.
-
(2004)
Drugs
, vol.64
, pp. 159-204
-
-
Li, X.Z.1
Nikaido, H.2
-
44
-
-
68949110351
-
Efflux-mediated drug resistance in bacteria
-
Drugs
-
Li XZ & Nikaido H (2009) Efflux-mediated drug resistance in bacteria: an update. Drugs 69: 1555-1623.
-
(2009)
an update
, vol.69
, pp. 1555-1623
-
-
Li, X.Z.1
Nikaido, H.2
-
45
-
-
12244293832
-
Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes
-
Li XZ, Poole K & Nikaido H (2003) Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes. Antimicrob Agents Ch47: 27-33.
-
(2003)
Antimicrob Agents Ch
, vol.47
, pp. 27-33
-
-
Li, X.Z.1
Poole, K.2
Nikaido, H.3
-
46
-
-
3042585064
-
Efflux pump-mediated intrinsic drug resistance in Mycobacterium smegmatis
-
Li XZ, Zhang L & Nikaido H (2004) Efflux pump-mediated intrinsic drug resistance in Mycobacterium smegmatis. Antimicrob Agents Ch48: 2415-2423.
-
(2004)
Antimicrob Agents Ch
, vol.48
, pp. 2415-2423
-
-
Li, X.Z.1
Zhang, L.2
Nikaido, H.3
-
47
-
-
0030013072
-
Active efflux of fluoroquinolones in Mycobacterium smegmatis mediated by LfrA, a multidrug efflux pump
-
Liu J, Takiff HE & Nikaido H (1996) Active efflux of fluoroquinolones in Mycobacterium smegmatis mediated by LfrA, a multidrug efflux pump. J Bacteriol178: 3791-3795.
-
(1996)
J Bacteriol
, vol.178
, pp. 3791-3795
-
-
Liu, J.1
Takiff, H.E.2
Nikaido, H.3
-
48
-
-
33644499476
-
Practical applications and feasibility of efflux pump inhibitors in the clinic-a vision for applied use
-
Lomovskaya O & Bostian KA (2006) Practical applications and feasibility of efflux pump inhibitors in the clinic-a vision for applied use. Biochem Pharmacol71: 910-918.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 910-918
-
-
Lomovskaya, O.1
Bostian, K.A.2
-
49
-
-
0035162640
-
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa
-
Antimicrob Agents Ch
-
Lomovskaya O, Warren MS, Lee Aet al. (2001) Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Ch 45: 105-116.
-
(2001)
novel agents for combination therapy
, vol.45
, pp. 105-116
-
-
Lomovskaya, O.1
Warren, M.S.2
Lee, A.3
-
50
-
-
67749145548
-
A balancing act
-
Antimicrob Agents Ch
-
Louw GE, Warren RM, Gey van Pittius NC, McEvoy CR, Van Helden PD & Victor TC (2009) A balancing act: efflux/influx in mycobacterial drug resistance. Antimicrob Agents Ch 53: 3181-3189.
-
(2009)
efflux/influx in mycobacterial drug resistance
, vol.53
, pp. 3181-3189
-
-
Louw, G.E.1
Warren, R.M.2
Gey van Pittius, N.C.3
McEvoy, C.R.4
Van Helden, P.D.5
Victor, T.C.6
-
51
-
-
80051572614
-
Rifampicin reduces susceptibility to ofloxacin in rifampicin resistant Mycobacterium tuberculosis through efflux
-
DOI:10.1164/rccm.201011-1924OC
-
Louw GE, Warren RM, Gey van Pittius NCet al. (2011) Rifampicin reduces susceptibility to ofloxacin in rifampicin resistant Mycobacterium tuberculosis through efflux. Am J Resp Crit Care, DOI:10.1164/rccm.201011-1924OC.
-
(2011)
Am J Resp Crit Care
-
-
Louw, G.E.1
Warren, R.M.2
Gey van Pittius, N.C.3
-
52
-
-
33750578428
-
An instrument-free method for the demonstration of efflux pump activity of bacteria
-
Martins M, Santos B, Martins A, Viveiros M, Couto I, Cruz A, Pages JM, Molnar J, Fanning S & Amaral L (2006) An instrument-free method for the demonstration of efflux pump activity of bacteria. In Vivo20: 657-664.
-
(2006)
In Vivo
, vol.20
, pp. 657-664
-
-
Martins, M.1
Santos, B.2
Martins, A.3
Viveiros, M.4
Couto, I.5
Cruz, A.6
Pages, J.M.7
Molnar, J.8
Fanning, S.9
Amaral, L.10
-
53
-
-
0032462726
-
Multidrug resistance following expression of the Escherichia coli marA gene in Mycobacterium smegmatis
-
McDermott PF, White DG, Podglajen I, Alekshun MN & Levy SB (1998) Multidrug resistance following expression of the Escherichia coli marA gene in Mycobacterium smegmatis. J Bacteriol180: 2995-2998.
-
(1998)
J Bacteriol
, vol.180
, pp. 2995-2998
-
-
McDermott, P.F.1
White, D.G.2
Podglajen, I.3
Alekshun, M.N.4
Levy, S.B.5
-
54
-
-
0345515642
-
Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli
-
McMurry L, Petrucci RE & Levy SB (1980) Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli. P Natl Acad Sci USA77: 3974-3977.
-
(1980)
P Natl Acad Sci USA
, vol.77
, pp. 3974-3977
-
-
McMurry, L.1
Petrucci, R.E.2
Levy, S.B.3
-
56
-
-
58149114923
-
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system
-
Milano A, Pasca MR, Provvedi R, Lucarelli AP, Manina G, Ribeiro AL, Manganelli R & Riccardi G (2009) Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system. Tuberculosis89: 84-90.
-
(2009)
Tuberculosis
, vol.89
, pp. 84-90
-
-
Milano, A.1
Pasca, M.R.2
Provvedi, R.3
Lucarelli, A.P.4
Manina, G.5
Ribeiro, A.L.6
Manganelli, R.7
Riccardi, G.8
-
57
-
-
24744436623
-
Ancestral antibiotic resistance in Mycobacterium tuberculosis
-
Morris RP, Nguyen L, Gatfield Jet al. (2005) Ancestral antibiotic resistance in Mycobacterium tuberculosis. P Natl Acad Sci USA102: 12200-12205.
-
(2005)
P Natl Acad Sci USA
, vol.102
, pp. 12200-12205
-
-
Morris, R.P.1
Nguyen, L.2
Gatfield, J.3
-
58
-
-
0032173598
-
Multiple antibiotic resistance and efflux
-
Nikaido H (1998) Multiple antibiotic resistance and efflux. Curr Opin Microbiol1: 516-523.
-
(1998)
Curr Opin Microbiol
, vol.1
, pp. 516-523
-
-
Nikaido, H.1
-
60
-
-
3042756785
-
Antibiotic susceptibility of glutaraldehyde-tolerant Mycobacterium chelonae from bronchoscope washing machines
-
Nomura K, Ogawa M, Miyamoto H, Muratani T & Taniguchi H (2004) Antibiotic susceptibility of glutaraldehyde-tolerant Mycobacterium chelonae from bronchoscope washing machines. Am J Infect Control32: 185-188.
-
(2004)
Am J Infect Control
, vol.32
, pp. 185-188
-
-
Nomura, K.1
Ogawa, M.2
Miyamoto, H.3
Muratani, T.4
Taniguchi, H.5
-
61
-
-
0037416986
-
Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis
-
Ordway D, Viveiros M, Leandro C, Bettencourt R, Almeida J, Martins M, Kristiansen JE, Molnar J & Amaral L (2003) Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis. Antimicrob Agents Ch47: 917-922.
-
(2003)
Antimicrob Agents Ch
, vol.47
, pp. 917-922
-
-
Ordway, D.1
Viveiros, M.2
Leandro, C.3
Bettencourt, R.4
Almeida, J.5
Martins, M.6
Kristiansen, J.E.7
Molnar, J.8
Amaral, L.9
-
63
-
-
33846420247
-
Brucella abortus bacA mutant induces greater pro-inflammatory cytokines than the wild-type parent strain
-
Parent MA, Goenka R, Murphy E, LeVier K, Carreiro N, Golding B, Ferguson G, Roop RM, Walker GC & Baldwin CL (2007) Brucella abortus bacA mutant induces greater pro-inflammatory cytokines than the wild-type parent strain. Microbes Infect9: 55-62.
-
(2007)
Microbes Infect
, vol.9
, pp. 55-62
-
-
Parent, M.A.1
Goenka, R.2
Murphy, E.3
LeVier, K.4
Carreiro, N.5
Golding, B.6
Ferguson, G.7
Roop, R.M.8
Walker, G.C.9
Baldwin, C.L.10
-
64
-
-
3342927606
-
Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis
-
Pasca MR, Guglierame P, Arcesi F, Bellinzoni M, De Rossi E & Riccardi G (2004) Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis. Antimicrob Agents Ch48: 3175-3178.
-
(2004)
Antimicrob Agents Ch
, vol.48
, pp. 3175-3178
-
-
Pasca, M.R.1
Guglierame, P.2
Arcesi, F.3
Bellinzoni, M.4
De Rossi, E.5
Riccardi, G.6
-
65
-
-
27644475760
-
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis
-
Pasca MR, Guglierame P, De Rossi E, Zara F & Riccardi G (2005) mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. Antimicrob Agents Ch49: 4775-4777.
-
(2005)
Antimicrob Agents Ch
, vol.49
, pp. 4775-4777
-
-
Pasca, M.R.1
Guglierame, P.2
De Rossi, E.3
Zara, F.4
Riccardi, G.5
-
66
-
-
0035084834
-
Microbial multidrug efflux
-
J Mol Microb Biotech
-
Paulsen IT & Lewis K (2001) Microbial multidrug efflux: introduction. J Mol Microb Biotech 3: 143-144.
-
(2001)
introduction
, vol.3
, pp. 143-144
-
-
Paulsen, I.T.1
Lewis, K.2
-
68
-
-
4544346542
-
Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation
-
Pethe K, Swenson DL, Alonso S, Anderson J, Wang C & Russell DG (2004) Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. P Natl Acad Sci USA101: 13642-13647.
-
(2004)
P Natl Acad Sci USA
, vol.101
, pp. 13642-13647
-
-
Pethe, K.1
Swenson, D.L.2
Alonso, S.3
Anderson, J.4
Wang, C.5
Russell, D.G.6
-
69
-
-
33646251815
-
Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria
-
Piddock LJ (2006a) Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin Microbiol Rev19: 382-402.
-
(2006)
Clin Microbiol Rev
, vol.19
, pp. 382-402
-
-
Piddock, L.J.1
-
70
-
-
33747154459
-
Multidrug-resistance efflux pumps - not just for resistance
-
Piddock LJ (2006b) Multidrug-resistance efflux pumps - not just for resistance. Nat Rev Microbiol4: 629-636.
-
(2006)
Nat Rev Microbiol
, vol.4
, pp. 629-636
-
-
Piddock, L.J.1
-
72
-
-
0032466234
-
Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis
-
Tuber Lung Dis
-
Ramaswamy S & Musser JM (1998) Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. Tuber Lung Dis 79: 3-29.
-
(1998)
1998 update
, vol.79
, pp. 3-29
-
-
Ramaswamy, S.1
Musser, J.M.2
-
73
-
-
31544466852
-
Characterization of tetracycline resistance mediated by the efflux pump Tap from Mycobacterium fortuitum
-
Ramon-Garcia S, Martin C, Ainsa JA & De Rossi E (2006) Characterization of tetracycline resistance mediated by the efflux pump Tap from Mycobacterium fortuitum. J Antimicrob Chemoth57: 252-259.
-
(2006)
J Antimicrob Chemoth
, vol.57
, pp. 252-259
-
-
Ramon-Garcia, S.1
Martin, C.2
Ainsa, J.A.3
De Rossi, E.4
-
74
-
-
34248189172
-
Contribution of the Rv2333c efflux pump (the Stp protein) from Mycobacterium tuberculosis to intrinsic antibiotic resistance in Mycobacterium bovis BCG
-
Ramon-Garcia S, Martin C, De Rossi E & Aínsa JA (2007) Contribution of the Rv2333c efflux pump (the Stp protein) from Mycobacterium tuberculosis to intrinsic antibiotic resistance in Mycobacterium bovis BCG. J Antimicrob Chemoth59: 544-547.
-
(2007)
J Antimicrob Chemoth
, vol.59
, pp. 544-547
-
-
Ramon-Garcia, S.1
Martin, C.2
De Rossi, E.3
Aínsa, J.A.4
-
75
-
-
70349154626
-
Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth
-
Ramón-García S, Martín C, Thompson CJ & Aínsa JA (2009) Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth. Antimicrob Agents Ch53: 3675-3682.
-
(2009)
Antimicrob Agents Ch
, vol.53
, pp. 3675-3682
-
-
Ramón-García, S.1
Martín, C.2
Thompson, C.J.3
Aínsa, J.A.4
-
76
-
-
42149168442
-
Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis
-
Rodrigues L, Wagner D, Viveiros M, Sampaio D, Couto I, Vavra M, Kern WV & Amaral L (2008) Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis. J Antimicrob Chemoth61: 1076-1082.
-
(2008)
J Antimicrob Chemoth
, vol.61
, pp. 1076-1082
-
-
Rodrigues, L.1
Wagner, D.2
Viveiros, M.3
Sampaio, D.4
Couto, I.5
Vavra, M.6
Kern, W.V.7
Amaral, L.8
-
78
-
-
0034560282
-
Contribution of the multidrug efflux pump LfrA to innate mycobacterial drug resistance
-
Sander P, De Rossi E, Boddinghaus B, Cantoni R, Branzoni M, Bottger EC, Takiff H, Rodriquez R, Lopez G & Riccardi G (2000) Contribution of the multidrug efflux pump LfrA to innate mycobacterial drug resistance. FEMS Microbiol Lett193: 19-23.
-
(2000)
FEMS Microbiol Lett
, vol.193
, pp. 19-23
-
-
Sander, P.1
De Rossi, E.2
Boddinghaus, B.3
Cantoni, R.4
Branzoni, M.5
Bottger, E.C.6
Takiff, H.7
Rodriquez, R.8
Lopez, G.9
Riccardi, G.10
-
79
-
-
0035991976
-
Salicylate reduces susceptibility of Mycobacterium tuberculosis to multiple antituberculosis drugs
-
Schaller A, Sun Z, Yang Y, Somoskovi A & Zhang Y (2002) Salicylate reduces susceptibility of Mycobacterium tuberculosis to multiple antituberculosis drugs. Antimicrob Agents Ch46: 2636-2639.
-
(2002)
Antimicrob Agents Ch
, vol.46
, pp. 2636-2639
-
-
Schaller, A.1
Sun, Z.2
Yang, Y.3
Somoskovi, A.4
Zhang, Y.5
-
80
-
-
77954710540
-
Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis
-
Sharma S, Kumar M, Sharma S, Nargotra A, Koul S & Khan IA (2010) Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis. J Antimicrob Chemoth65: 1694-1701.
-
(2010)
J Antimicrob Chemoth
, vol.65
, pp. 1694-1701
-
-
Sharma, S.1
Kumar, M.2
Sharma, S.3
Nargotra, A.4
Koul, S.5
Khan, I.A.6
-
81
-
-
1842451933
-
Mycobacterium tuberculosis isolate with a distinct genomic identity overexpresses a tap-like efflux pump
-
Siddiqi N, Das R, Pathak N, Banerjee S, Ahmed N, Katoch VM & Hasnain SE (2004) Mycobacterium tuberculosis isolate with a distinct genomic identity overexpresses a tap-like efflux pump. Infection32: 109-111.
-
(2004)
Infection
, vol.32
, pp. 109-111
-
-
Siddiqi, N.1
Das, R.2
Pathak, N.3
Banerjee, S.4
Ahmed, N.5
Katoch, V.M.6
Hasnain, S.E.7
-
82
-
-
0035115179
-
Characterization of P55, a multidrug efflux pump in Mycobacterium bovis and Mycobacterium tuberculosis
-
Silva PE, Bigi F, Santangelo MP, Romano MI, Martín C, Cataldi A & Aínsa JA (2001) Characterization of P55, a multidrug efflux pump in Mycobacterium bovis and Mycobacterium tuberculosis. Antimicrob Agents Ch45: 800-804.
-
(2001)
Antimicrob Agents Ch
, vol.45
, pp. 800-804
-
-
Silva, P.E.1
Bigi, F.2
Santangelo, M.P.3
Romano, M.I.4
Martín, C.5
Cataldi, A.6
Aínsa, J.A.7
-
83
-
-
48749090737
-
Identification of mutations related to streptomycin resistance in clinical isolates of Mycobacterium tuberculosis and possible involvement of efflux mechanism
-
Spies FS, da Silva PE, Ribeiro MO, Rossetti ML & Zaha A (2008) Identification of mutations related to streptomycin resistance in clinical isolates of Mycobacterium tuberculosis and possible involvement of efflux mechanism. Antimicrob Agents Ch52: 2947-2949.
-
(2008)
Antimicrob Agents Ch
, vol.52
, pp. 2947-2949
-
-
Spies, F.S.1
da Silva, P.E.2
Ribeiro, M.O.3
Rossetti, M.L.4
Zaha, A.5
-
84
-
-
0030058375
-
Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis
-
Takiff HE, Cimino M, Musso MC, Weisbrod T, Martinez R, Delgado MB, Salazar L, Bloom BR & Jacobs WRJr (1996) Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis. P Natl Acad Sci USA93: 362-366.
-
(1996)
P Natl Acad Sci USA
, vol.93
, pp. 362-366
-
-
Takiff, H.E.1
Cimino, M.2
Musso, M.C.3
Weisbrod, T.4
Martinez, R.5
Delgado, M.B.6
Salazar, L.7
Bloom, B.R.8
Jacobs Jr., W.R.9
-
85
-
-
0033170990
-
-
Tseng TT, Gratwick KS, Kollman J, Park D, Nies DH, Goffeau A & Saier MHJr (1999) J Mol Microb Biotech1: 107-125.
-
(1999)
J Mol Microb Biotech
, vol.1
, pp. 107-125
-
-
Tseng, T.T.1
Gratwick, K.S.2
Kollman, J.3
Park, D.4
Nies, D.H.5
Goffeau, A.6
Saier Jr., M.H.7
-
86
-
-
77958612298
-
The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis
-
van Soolingen D, Hernandez-Pando R, Orozco H, Aguilar D, Magis-Escurra C, Amaral L, van Ingen J & Boeree MJ (2010) The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. PLoS One5: e12640.
-
(2010)
PLoS One
, vol.5
-
-
van Soolingen, D.1
Hernandez-Pando, R.2
Orozco, H.3
Aguilar, D.4
Magis-Escurra, C.5
Amaral, L.6
van Ingen, J.7
Boeree, M.J.8
-
87
-
-
0036719989
-
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis
-
Viveiros M, Portugal I, Bettencourt R, Victor TC, Jordaan AM, Leandro C, Ordway D & Amaral L (2002) Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis. Antimicrob Agents Ch46: 2804-2810.
-
(2002)
Antimicrob Agents Ch
, vol.46
, pp. 2804-2810
-
-
Viveiros, M.1
Portugal, I.2
Bettencourt, R.3
Victor, T.C.4
Jordaan, A.M.5
Leandro, C.6
Ordway, D.7
Amaral, L.8
-
88
-
-
52449115307
-
New methods for the identification of efflux mediated MDR bacteria, genetic assessment of regulators and efflux pump constituents, characterization of efflux systems and screening for inhibitors of efflux pumps
-
Viveiros M, Martins M, Couto I, Rodrigues L, Spengler G, Martins A, Kristiansen JE, Molnar J & Amaral L (2008) New methods for the identification of efflux mediated MDR bacteria, genetic assessment of regulators and efflux pump constituents, characterization of efflux systems and screening for inhibitors of efflux pumps. Curr Drug Targets9: 760-778.
-
(2008)
Curr Drug Targets
, vol.9
, pp. 760-778
-
-
Viveiros, M.1
Martins, M.2
Couto, I.3
Rodrigues, L.4
Spengler, G.5
Martins, A.6
Kristiansen, J.E.7
Molnar, J.8
Amaral, L.9
-
89
-
-
0037257321
-
The importance of efflux pumps in bacterial antibiotic resistance
-
Webber MA & Piddock LJ (2003) The importance of efflux pumps in bacterial antibiotic resistance. J Antimicrob Chemoth51: 9-11.
-
(2003)
J Antimicrob Chemoth
, vol.51
, pp. 9-11
-
-
Webber, M.A.1
Piddock, L.J.2
-
90
-
-
0033607188
-
Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization
-
Wilson M, DeRisi J, Kristensen HH, Imboden P, Rane S, Brown PO & Schoolnik GK (1999) Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization. P Natl Acad Sci USA96: 12833-12838.
-
(1999)
P Natl Acad Sci USA
, vol.96
, pp. 12833-12838
-
-
Wilson, M.1
DeRisi, J.2
Kristensen, H.H.3
Imboden, P.4
Rane, S.5
Brown, P.O.6
Schoolnik, G.K.7
-
91
-
-
80052581557
-
-
World Health Organization. Anti-tuberculosis drug resistance in the world. The WHO/IUATLD Global Project on Anti-tuberculosis Drug Resistance Surveillance 1994-1997. Geneva, World Health Organization, 1997 (WHO/TB/97.229)
-
World Health Organization (1997) Anti-tuberculosis drug resistance in the world. The WHO/IUATLD Global Project on Anti-tuberculosis Drug Resistance Surveillance 1994-1997. Geneva, World Health Organization, 1997 (WHO/TB/97.229).
-
(1997)
-
-
-
93
-
-
80052557411
-
-
World Health Organization. Multidrug and extensively drug-resistant TB (M/XDR-TB): 2010 global report on surveillance and response. 2010. WHO/HTM/TB/2010.3
-
World Health Organization (2010b) Multidrug and extensively drug-resistant TB (M/XDR-TB): 2010 global report on surveillance and response. 2010. WHO/HTM/TB/2010.3.
-
(2010)
-
-
-
94
-
-
0030840548
-
Quinolone susceptibility of norA-disrupted Staphylococcus aureus
-
Yamada H, Kurose-Hamada S, Fukuda Y, Mitsuyama J, Takahata M, Minami S, Watanabe Y & Narita H (1997) Quinolone susceptibility of norA-disrupted Staphylococcus aureus. Antimicrob Agents Ch41: 2308-2309.
-
(1997)
Antimicrob Agents Ch
, vol.41
, pp. 2308-2309
-
-
Yamada, H.1
Kurose-Hamada, S.2
Fukuda, Y.3
Mitsuyama, J.4
Takahata, M.5
Minami, S.6
Watanabe, Y.7
Narita, H.8
-
95
-
-
0000652832
-
Genetics of drug resistance in Mycobacterium tuberculosis
-
HatfullGF & JacobsWR, ed) ASM, Washington, DC
-
Zhang Y & Telenti A (2000) Genetics of drug resistance in Mycobacterium tuberculosis. Molecular Genetics of Mycobacteria (Hatfull GF & Jacobs WR, ed), pp. 235-254. ASM, Washington, DC.
-
(2000)
Molecular Genetics of Mycobacteria
, pp. 235-254
-
-
Zhang, Y.1
Telenti, A.2
|