Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

Molecular Cell

Volumn 37, Issue 3, 2010, Pages 311-320

  Kohanski, Michael A ^a,b,c   DePristo, Mark A ^a,b,d   Collins, James J ^a,b,c,d  

^a BOSTON UNIVERSITY   (United States)

^b Boston University   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD UNIVERSITY   (United States)

Author keywords

DNA; HUMDISEASE; MICROBIO

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; KANAMYCIN; NORFLOXACIN; OXYGEN RADICAL; TETRACYCLINE;

ARTICLE; BACTERIAL MUTATION; CHEMICAL MUTAGENESIS; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MUTATION RATE; NONHUMAN; OXIDATIVE STRESS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; GENE TRANSFER, HORIZONTAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; REACTIVE OXYGEN SPECIES; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN;

EID: 75949092532     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.01.003     Document Type: Article

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