-
1
-
-
0028156861
-
InhA, a gene encoding a target for isoniazid and ethionamide resistance in Mycobacterium tuberculosis
-
Banerjee, A., E. Dubnau, A. Quémard, V. Balasubramanian, K. S. Um, T. Wilson, D. Collins, G. de Lisle, and W. R. Jacobs. 1994. inhA, a gene encoding a target for isoniazid and ethionamide resistance in Mycobacterium tuberculosis. Science 263:227-230.
-
(1994)
Science
, vol.263
, pp. 227-230
-
-
Banerjee, A.1
Dubnau, E.2
Quémard, A.3
Balasubramanian, V.4
Um, K.S.5
Wilson, T.6
Collins, D.7
De Lisle, G.8
Jacobs, W.R.9
-
2
-
-
0345034826
-
-
Personal communication
-
1a.Barry, C. Personal communication.
-
-
-
Barry, C.1
-
3
-
-
0029959745
-
The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid
-
Deretic, V., E. Pagan-Ramos, Y. Zhang, S. Dhandayuthapani, and L. Via. 1996. The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid. Nat. Biotechnol. 14:1557-1561.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 1557-1561
-
-
Deretic, V.1
Pagan-Ramos, E.2
Zhang, Y.3
Dhandayuthapani, S.4
Via, L.5
-
4
-
-
0028988237
-
Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis
-
Dessen, A., A. Quémard, J. Blanchard, W. Jacobs, and J. C. Sacchettini. 1995. Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis. Science 267:1638-1641.
-
(1995)
Science
, vol.267
, pp. 1638-1641
-
-
Dessen, A.1
Quémard, A.2
Blanchard, J.3
Jacobs, W.4
Sacchettini, J.C.5
-
5
-
-
0029888258
-
Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: Characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis
-
Dhandayuthapani, S., Y. Zhang, M. H. Mudd, and V. Deretic. 1996. Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis. J. Bacteriol. 178:3641-3649.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 3641-3649
-
-
Dhandayuthapani, S.1
Zhang, Y.2
Mudd, M.H.3
Deretic, V.4
-
6
-
-
0020315535
-
Oxygen toxicity in Streptococcus sanguis: The relative importance of superoxide and hydroxyl radicals
-
DiGuiseppe, J., and I. Fridovich. 1982. Oxygen toxicity in Streptococcus sanguis: the relative importance of superoxide and hydroxyl radicals. J. Biol. Chem. 257:4046-4051.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 4046-4051
-
-
DiGuiseppe, J.1
Fridovich, I.2
-
7
-
-
0029913211
-
Molecular characterization of a surface-exposed superoxide dismutase of Mycobacterium avium
-
Escuyer, V., N. Haddod, C. Frehel, and P. Berche. 1996. Molecular characterization of a surface-exposed superoxide dismutase of Mycobacterium avium. Microb. Pathog. 20:41-55.
-
(1996)
Microb. Pathog.
, vol.20
, pp. 41-55
-
-
Escuyer, V.1
Haddod, N.2
Frehel, C.3
Berche, P.4
-
8
-
-
0028960179
-
Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis
-
Heym, B., P. Alzari, N. Honore, and S. Cole. 1995. Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis. Mol. Microbiol. 15:235-245.
-
(1995)
Mol. Microbiol.
, vol.15
, pp. 235-245
-
-
Heym, B.1
Alzari, P.2
Honore, N.3
Cole, S.4
-
9
-
-
0026795159
-
Isolation and characterization of isoniazid-resistant mutants of Mycobacterium smegmatis and M. aurum
-
Heym, B., and S. T. Cole. 1992. Isolation and characterization of isoniazid-resistant mutants of Mycobacterium smegmatis and M. aurum. Res. Microbiol. 143:721-730.
-
(1992)
Res. Microbiol.
, vol.143
, pp. 721-730
-
-
Heym, B.1
Cole, S.T.2
-
10
-
-
0026443736
-
Manganese-mediated oxidative damage of cellular and isolated DNA by isoniazid and related hydrazines: Non-Fenton-type hydroxyl radical formation
-
Ito, K., K. Yamamoto, and S. Kawanishi. 1992. Manganese-mediated oxidative damage of cellular and isolated DNA by isoniazid and related hydrazines: non-Fenton-type hydroxyl radical formation. Biochemistry 31:11606-11613.
-
(1992)
Biochemistry
, vol.31
, pp. 11606-11613
-
-
Ito, K.1
Yamamoto, K.2
Kawanishi, S.3
-
11
-
-
0029042636
-
Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis
-
Johnsson, K., D. King, and P. Schultz. 1995. Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis. J. Am. Chem. Soc. 117:5009-5010.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 5009-5010
-
-
Johnsson, K.1
King, D.2
Schultz, P.3
-
12
-
-
0027993499
-
Mechanistic studies of the oxidation of isoniazid by the catalase peroxidase from Mycobacterium tuberculosis
-
Johnsson, K., and P. Schultz. 1994. Mechanistic studies of the oxidation of isoniazid by the catalase peroxidase from Mycobacterium tuberculosis. J. Am. Chem. Soc. 116:7425-7426.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 7425-7426
-
-
Johnsson, K.1
Schultz, P.2
-
14
-
-
0015242573
-
Controlled clinical trial of clofazimine in untreated lepromatous leprosy
-
Karat, A. B., A. Jeevaratnam, S. Karat, and P. S. Rao. 1971. Controlled clinical trial of clofazimine in untreated lepromatous leprosy. Br. Med. J. 4:514-516.
-
(1971)
Br. Med. J.
, vol.4
, pp. 514-516
-
-
Karat, A.B.1
Jeevaratnam, A.2
Karat, S.3
Rao, P.S.4
-
15
-
-
0029912749
-
Evidence for isoniazid oxidation to oxyferrous mycobacterial catalase-peroxidase
-
Magliozzo, R. S., and J. A. Marcinkeviciene. 1996. Evidence for isoniazid oxidation to oxyferrous mycobacterial catalase-peroxidase. J. Am. Chem. Soc. 118:11303-11304.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 11303-11304
-
-
Magliozzo, R.S.1
Marcinkeviciene, J.A.2
-
16
-
-
0029859098
-
Biochemical and genetic data suggest that InhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis
-
Mdluli, K., D. Sherman, M. Hickey, B. Kreiswirth, S. Morris, C. K. Stover, and C. E. Barry. 1996. Biochemical and genetic data suggest that InhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis. J. Infect. Dis. 174:1085-1090.
-
(1996)
J. Infect. Dis.
, vol.174
, pp. 1085-1090
-
-
Mdluli, K.1
Sherman, D.2
Hickey, M.3
Kreiswirth, B.4
Morris, S.5
Stover, C.K.6
Barry, C.E.7
-
17
-
-
0025852177
-
Isoniazid inhibition of mycolic acid synthesis by cell extracts of sensitive and resistant strains of Mycobacterium aurum
-
Quémard, A., C. Lacave, and G. Lanéelle. 1991. Isoniazid inhibition of mycolic acid synthesis by cell extracts of sensitive and resistant strains of Mycobacterium aurum. Antimicrob. Agents Chemother. 35:1035-1039.
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 1035-1039
-
-
Quémard, A.1
Lacave, C.2
Lanéelle, G.3
-
18
-
-
0029995215
-
Antituberculosis activities of clofazimine and its new analogs B4154 and B4157
-
Reddy, V. M., G. Nadadhur, D. Daneluzzi, J. F. O'Sullivan, and P. R. J. Gangadharam. 1996. Antituberculosis activities of clofazimine and its new analogs B4154 and B4157. Antimicrob. Agents Chemother. 40:633-636.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 633-636
-
-
Reddy, V.M.1
Nadadhur, G.2
Daneluzzi, D.3
O'Sullivan, J.F.4
Gangadharam, P.R.J.5
-
19
-
-
0027937662
-
Effects of peroxides on susceptibilities of Escherichia coli and Mycobacterium smegmatis to isoniazid
-
Rosner, J. L., and G. Storz. 1994. Effects of peroxides on susceptibilities of Escherichia coli and Mycobacterium smegmatis to isoniazid. Antimicrob. Agents Chemother. 38:1829-1833.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1829-1833
-
-
Rosner, J.L.1
Storz, G.2
-
20
-
-
0021993496
-
Enzymatic and nonenzymatic superoxide-generating reactions of isoniazid
-
Shoeb, H. A., B. U. Bowman, Jr., A. C. Ottolenghi, and A. J. Merola. 1985. Enzymatic and nonenzymatic superoxide-generating reactions of isoniazid. Antimicrob. Agents Chemother. 27:408-412.
-
(1985)
Antimicrob. Agents Chemother.
, vol.27
, pp. 408-412
-
-
Shoeb, H.A.1
Bowman B.U., Jr.2
Ottolenghi, A.C.3
Merola, A.J.4
-
21
-
-
0021963581
-
Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra
-
Shoeb, H. A., B. U. Bowman, Jr., A. C. Ottolenghi, and A. J. Merola. 1985. Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra. Antimicrob. Agents Chemother. 27:404-407.
-
(1985)
Antimicrob. Agents Chemother.
, vol.27
, pp. 404-407
-
-
Shoeb, H.A.1
Bowman B.U., Jr.2
Ottolenghi, A.C.3
Merola, A.J.4
-
22
-
-
0015373050
-
Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis
-
Takayama, K., L. Wang, and H. L. David. 1972. Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2:29-35.
-
(1972)
Antimicrob. Agents Chemother.
, vol.2
, pp. 29-35
-
-
Takayama, K.1
Wang, L.2
David, H.L.3
-
23
-
-
0029988592
-
Action of clofazimine on the Mycobacterium avium complex
-
Warek, U., and J. O. Falkinham III. 1996. Action of clofazimine on the Mycobacterium avium complex. Res. Microbiol. 147:43-48.
-
(1996)
Res. Microbiol.
, vol.147
, pp. 43-48
-
-
Warek, U.1
Falkinham J.O. III2
-
24
-
-
0030892547
-
The requirement for manganese and oxygen in the isoniazid-dependent inactivation of Mycobacterium tuberculosis enoyl reductase
-
Zabinski, R. F., and J. S. Blanchard. 1997. The requirement for manganese and oxygen in the isoniazid-dependent inactivation of Mycobacterium tuberculosis enoyl reductase. J. Am. Chem. Soc. 119:2331-2332.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 2331-2332
-
-
Zabinski, R.F.1
Blanchard, J.S.2
-
25
-
-
0029830769
-
Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid
-
USA
-
Zhang, Y., S. Dhandayuthapani, and V. Deretic. 1996. Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid. Proc. Natl. Acad. Sci. USA 93:13212-13216.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 13212-13216
-
-
Zhang, Y.1
Dhandayuthapani, S.2
Deretic, V.3
-
26
-
-
0026705772
-
The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis
-
Zhang, Y., B. Heym, B. Allen, D. Young, and S. Cole. 1992. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Nature 358:591-593.
-
(1992)
Nature
, vol.358
, pp. 591-593
-
-
Zhang, Y.1
Heym, B.2
Allen, B.3
Young, D.4
Cole, S.5
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