Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling

Chemico-Biological Interactions

Volumn 209, Issue 1, 2014, Pages 56-67

  Li, Lingrui ^a   Dong, Hui ^a   Song, Erqun ^a   Xu, Xiaoyu ^a   Liu, Lichao ^a   Song, Yang ^a  

^a SOUTHWEST UNIVERSITY   (China)

Author keywords

HO 1; Keap1; MAPK; NQO1; PCB; ROS

Indexed keywords

2,3,5 TRICHLORO 6 PHENYL [1,4]BENZOQUINONE; GLYCOGEN SYNTHASE KINASE 3BETA; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ADAPTATION; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL NUCLEUS; CELL STRAIN HEPG2; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LUCIFERASE ASSAY; OXIDATIVE STRESS; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

HO-1; KEAP1; MAPK; NQO1; PCB; ROS;

BENZOQUINONES; BLOTTING, WESTERN; ELAFIN; ENVIRONMENTAL POLLUTANTS; ENZYMES; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR STRUCTURE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; ONCOGENE PROTEIN V-AKT; POLYCHLORINATED BIPHENYLS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; VESICULAR TRANSPORT PROTEINS;

EID: 84891712243     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.12.005     Document Type: Article

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