Cytotoxic effects of polychlorinated biphenyl hydroquinone metabolites in rat hepatocytes

Journal of Applied Toxicology

Volumn 30, Issue 2, 2010, Pages 163-171

  Chan, Katie ^a   Lehmler, Hans Joachim ^b   Sivagnanam, Milani ^a   Feng, Cynthia Yan ^a   Robertson, Larry ^b   O'Brien, Peter J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

2 (x chlorophenyl) 1,4 hydroquinone; Glutathione; Hepatocytes; Hydroquinone; Mitochondria; Oxidative stress; Polychlorinated biphenyls

Indexed keywords

2 (2' CHLOROPHENYL) 1,4 HYDROQUINONE; 2 (3' CHLOROPHENYL) 1,4 HYDROQUINONE; 2 (4' CHLOROPHENYL) 1,4 HYDROQUINONE; CYTOCHROME P450; ELECTROPHILE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; HYDROQUINONE DERIVATIVE; PHENYLHYDROQUINONE; POLYCHLORINATED BIPHENYL; QUINONE DERIVATIVE; SEMIQUINONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOOXIDATION; CELL DEATH; CELL ISOLATION; CELLULAR IMMUNITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; GLUTATHIONE METABOLISM; LIVER CELL; MALE; METABOLITE; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; CELL DEATH; GLUTATHIONE; HEPATOCYTES; HYDROQUINONES; MALE; OXIDATION-REDUCTION; POLYCHLORINATED BIPHENYLS; QUINONES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; RATTUS;

EID: 77249124390     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1483     Document Type: Article

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