The toxic effects of Aroclor 1254 exposure on the osteoblastic cell line MC3T3-E1 and its molecular mechanism

Toxicology

Volumn 295, Issue 1-3, 2012, Pages 8-14

  An, Jing ^a   Zou, Wen ^a   Zhong, Yufang ^a   Zhang, Xinyu ^a   Wu, Minghong ^a   Yu, Zhiqiang ^b   Ye, Tianwen ^c  

^a SHANGHAI UNIVERSITY   (China)

^b GUANGZHOU INSTITUTE OF GEOCHEMISTRY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

ALP activity; Apaf 1; Apoptosis; Aroclor 1254; Cell proliferation; MC3T3 E1 cell; ROS; TRPV6

Indexed keywords

ALKALINE PHOSPHATASE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; AROCLOR 1254; CALCIUM ION; POLYCHLORINATED BIPHENYL; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; VANILLOID RECEPTOR 6; CALCIUM; CALCIUM CHANNEL; TRPV6 PROTEIN, MOUSE; VANILLOID RECEPTOR;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DOSE RESPONSE; DRUG EXPOSURE; ENZYME ACTIVITY; IMMUNOFLUORESCENCE; MOLECULAR MECHANICS; OSTEOBLAST; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL STRAIN 3T3; DRUG EFFECT; METABOLISM; MOUSE; PATHOLOGY;

3T3 CELLS; ALKALINE PHOSPHATASE; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM CHANNELS; CELL PROLIFERATION; CHLORODIPHENYL (54% CHLORINE); MICE; OSTEOBLASTS; REACTIVE OXYGEN SPECIES; TRPV CATION CHANNELS;

EID: 84861112616     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.02.009     Document Type: Article

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