Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation

Nature Communications

Volumn 4, Issue , 2013, Pages

  Min, Wookee ^a   Bruhn, Christopher ^a   Grigaravicius, Paulius ^a,e   Zhou, Zhong Wei ^a   Li, Fu ^a   Krüger, Anja ^a   Siddeek, Bénazir ^a   Greulich, Karl Otto ^a,b   Popp, Oliver ^c   Meisezahl, Chris ^a   Calkhoven, Cornelis F ^a   Bürkle, Alexander ^c   Xu, Xingzhi ^d   Wang, Zhao Qi ^a,b  

^a FRITZ LIPMANN INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c UNIVERSITY OF KONSTANZ   (Germany)

^d CAPITAL NORMAL UNIVERSITY   (China)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CHECKPOINT KINASE 1; CLASPIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; METABOLISM; MUTATION; PHOSPHORUS; PROTEIN;

ANIMAL CELL; ARTICLE; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME METABOLISM; ENZYME PHOSPHORYLATION; GENE; GENE MUTATION; GENE SILENCING; HOMEOSTASIS; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PBR GENE; PROTEIN FUNCTION; REGULATORY MECHANISM; S PHASE CELL CYCLE CHECKPOINT;

3T3 CELLS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHROMATIN; COS CELLS; DNA DAMAGE; DNA REPLICATION; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; PROTEIN KINASES; RECOMBINANT PROTEINS; S PHASE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84890935685     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3993     Document Type: Article

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