메뉴 건너뛰기




Volumn 136, Issue 11, 2013, Pages 3305-3332

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis; Genetic background; Immune system; Motor neurons; SOD1

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ANGIOGENIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; COMPLEMENT COMPONENT C3; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIN D1; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 9; JANUS KINASE 1; JANUS KINASE 2; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 5; ONCOSTATIN M; ONCOSTATIN M RECEPTOR; PROTEIN C FOS; PROTEIN KINASE TYK2; SNARE PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; SYNAPTOBREVIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SOX6; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCOUPLING PROTEIN 2;

EID: 84890469438     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt250     Document Type: Article
Times cited : (71)

References (182)
  • 1
    • 84873053822 scopus 로고    scopus 로고
    • Axon pathology in age-related neurodegenerativedis orders
    • Adalbert R, Coleman MP. Axon pathology in age-related neurodegenerativedis orders. Neuropathol Appl Neurobiol 2013; 39: 90-108.
    • (2013) Neuropathol Appl Neurobiol , vol.39 , pp. 90-108
    • Adalbert, R.1    Coleman, M.P.2
  • 3
    • 84870861262 scopus 로고    scopus 로고
    • Molecular mechanisms in amyotrophic lateral sclerosis: The role of angiogenin, a secreted rnase
    • Aparicio-Erriu IM, Prehn JH. Molecular mechanisms in amyotrophic lateral sclerosis: the role of angiogenin, a secreted RNase. Front Neurosci 2012; 6: 167.
    • (2012) Front Neurosci , vol.6 , pp. 167
    • Aparicio-Erriu, I.M.1    Prehn, J.H.2
  • 4
    • 73149116008 scopus 로고    scopus 로고
    • T cell-microglial dialogue in parkinson's disease and amyotrophic lateral sclerosis: Are we listening?
    • Appel SH, Beers DR, Henkel JS. T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listeninǧTrends Immunol 2010; 31: 7-17.
    • (2010) Trends Immunol , vol.31 , pp. 7-17
    • Appel, S.H.1    Beers, D.R.2    Henkel, J.S.3
  • 5
    • 0037138391 scopus 로고    scopus 로고
    • Roles of mouse ubc13 in dna postreplication repair and lys63-linked ubiquitination
    • Ashley C, Pastushok L, McKenna S, Ellison MJ, Xiao W. Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination. Gene 2002; 285: 183-91.
    • (2002) Gene , vol.285 , pp. 183-191
    • Ashley, C.1    Pastushok, L.2    McKenna, S.3    Ellison, M.J.4    Xiao, W.5
  • 7
    • 75149155060 scopus 로고    scopus 로고
    • Oxidative stress in als: Key role in motor neuron injury and therapeutic target
    • Barber SC, Shaw PJ. Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radic Biol Med 2010; 48: 629-41.
    • (2010) Free Radic Biol Med , vol.48 , pp. 629-641
    • Barber, S.C.1    Shaw, P.J.2
  • 8
    • 25844496913 scopus 로고    scopus 로고
    • Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis
    • Baron P, Bussini S, Cardin V, Corbo M, Conti G, Galimberti D, et al. Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis. Muscle Nerve 2005; 32: 541-4.
    • (2005) Muscle Nerve , vol.32 , pp. 541-544
    • Baron, P.1    Bussini, S.2    Cardin, V.3    Corbo, M.4    Conti, G.5    Galimberti, D.6
  • 9
    • 77949505299 scopus 로고    scopus 로고
    • Characterization of detergent-insoluble proteins in als indicates a causal link between nitrative stress and aggregation in pathogenesis
    • Basso M, Samengo G, Nardo G, Massignan T, D'Alessandro G, Tartari S, et al. Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis. PLoS One 2009; 4: e8130.
    • (2009) PLoS One , vol.4
    • Basso, M.1    Samengo, G.2    Nardo, G.3    Massignan, T.4    D'Alessandro, G.5    Tartari, S.6
  • 10
    • 55749110043 scopus 로고    scopus 로고
    • Cd4 + t cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited als
    • Beers DR, Henkel JS, Zhao W, Wang J, Appel SH. CD4 + T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc Natl Acad Sci USA 2008; 105: 15558-63.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15558-15563
    • Beers, D.R.1    Henkel, J.S.2    Zhao, W.3    Wang, J.4    Appel, S.H.5
  • 11
    • 79957528028 scopus 로고    scopus 로고
    • Endogenous regulatory t lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
    • Beers DR, Henkel JS, Zhao W, Wang J, Huang A, Wen S, et al. Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis. Brain 2011; 134: 1293-314.
    • (2011) Brain , vol.134 , pp. 1293-1314
    • Beers, D.R.1    Henkel, J.S.2    Zhao, W.3    Wang, J.4    Huang, A.5    Wen, S.6
  • 12
    • 37549000493 scopus 로고    scopus 로고
    • The heterogeneity of amyotrophic lateral sclerosis: A possible explanation of treatment failure
    • Beghi E, Mennini T, Bendotti C, Bigini P, Logroscino G, Chioa, et al. The heterogeneity of amyotrophic lateral sclerosis: a possible explanation of treatment failure. Curr Med Chem 2007; 14: 3185-200.
    • (2007) Curr Med Chem , vol.14 , pp. 3185-3200
    • Beghi, E.1    Mennini, T.2    Bendotti, C.3    Bigini, P.4    Logroscino, G.5    Chioa, A.6
  • 13
    • 4043075622 scopus 로고    scopus 로고
    • Lessons from models of sod1-linked familial als
    • Bendotti C, Carrì MT. Lessons from models of SOD1-linked familial ALS. Trends Mol Med 2004; 10: 393-400.
    • (2004) Trends Mol Med , vol.10 , pp. 393-400
    • Bendotti, C.1    Carrì, M.T.2
  • 14
    • 84860683749 scopus 로고    scopus 로고
    • Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: Implication for protein aggregation and immune response
    • Bendotti C, Marino M, Cheroni C, Fontana E, Crippa V, Poletti A, et al. Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response. Prog Neurobiol 2012; 97: 101-26.
    • (2012) Prog Neurobiol , vol.97 , pp. 101-126
    • Bendotti, C.1    Marino, M.2    Cheroni, C.3    Fontana, E.4    Crippa, V.5    Poletti, A.6
  • 15
    • 79952273376 scopus 로고    scopus 로고
    • Complement protein c1q-mediated neuroprotection is correlated with regulation of neuronal gene and microrna expression
    • Benoit ME, Tenner AJ. Complement protein C1q-mediated neuroprotection is correlated with regulation of neuronal gene and microRNA expression. J Neurosci 2011; 31: 3459-69.
    • (2011) J Neurosci , vol.31 , pp. 3459-3369
    • Benoit, M.E.1    Tenner, A.J.2
  • 19
    • 33749056809 scopus 로고    scopus 로고
    • Als: A disease of motor neurons and their nonneuronal neighbors
    • Boillee S, Vande Velde C, Cleveland DW. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron 2006b; 52: 39-59.
    • (2006) Neuron , vol.52 , pp. 39-59
    • Boillee, S.1    Vande Velde, C.2    Cleveland, D.W.3
  • 20
    • 0035477393 scopus 로고    scopus 로고
    • Neuronal plasticity and cellular immunity: Shared molecular mechanisms
    • Boulanger LM, Huh GS, Shatz CJ. Neuronal plasticity and cellular immunity: shared molecular mechanisms. Curr Opin Neurobiol 2001; 11: 568-78.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 568-578
    • Boulanger, L.M.1    Huh, G.S.2    Shatz, C.J.3
  • 21
    • 3042841709 scopus 로고    scopus 로고
    • Immune signalling in neural development, synaptic plasticity and disease
    • Boulanger LM, Shatz CJ. Immune signalling in neural development, synaptic plasticity and disease. Nat Rev Neurosci 2004; 5: 521-31.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 521-531
    • Boulanger, L.M.1    Shatz, C.J.2
  • 22
    • 39049108407 scopus 로고    scopus 로고
    • Activating transcription factor 3 is a novel repressor of the nuclear factor erythroid-derived 2-related factor 2 (nrf2)-regulated stress pathway
    • Brown SL, Sekhar KR, Rachakonda G, Sasi S, Freeman ML. Activating transcription factor 3 is a novel repressor of the nuclear factor erythroid-derived 2-related factor 2 (Nrf2)-regulated stress pathway. Cancer Res 2008; 68: 364-8.
    • (2008) Cancer Res , vol.68 , pp. 364-368
    • Brown, S.L.1    Sekhar, K.R.2    Rachakonda, G.3    Sasi, S.4    Freeman, M.L.5
  • 24
    • 70450224446 scopus 로고    scopus 로고
    • Multiple roles of the vesicular-snare tivamp in post-golgi and endosomal trafficking
    • Chaineau M, Danglot L, Galli T. Multiple roles of the vesicular-SNARE TIVAMP in post-Golgi and endosomal trafficking. FEBS Lett 2009; 583: 3817-26.
    • (2009) FEBS Lett , vol.583 , pp. 3817-3826
    • Chaineau, M.1    Danglot, L.2    Galli, T.3
  • 26
    • 78650048929 scopus 로고    scopus 로고
    • Characterization of the properties of a novel mutation in vapb in familial amyotrophic lateral sclerosis
    • Chen HJ, Anagnostou G, Chai A, Withers J, Morris A, Adhikaree J, et al. Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis. J Biol Chem 2010; 285: 40266-81.
    • (2010) J Biol Chem , vol.285 , pp. 40266-40281
    • Chen, H.J.1    Anagnostou, G.2    Chai, A.3    Withers, J.4    Morris, A.5    Adhikaree, J.6
  • 27
    • 4344596581 scopus 로고    scopus 로고
    • Oncostatin m: A pleiotropic cytokine in the central nervous system
    • Chen SH, Benveniste EN. Oncostatin M: a pleiotropic cytokine in the central nervous system. Cytokine Growth Factor Rev 2004; 15: 379-91.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 379-391
    • Chen, S.H.1    Benveniste, E.N.2
  • 28
    • 33644804678 scopus 로고    scopus 로고
    • Divergent effects of oncostatin m on astroglioma cells: Influence on cell proliferation, invasion, and expression of matrix metalloproteinases
    • Chen SH, Gillespie GY, Benveniste EN. Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases. Glia 2006; 53: 191-200.
    • (2006) Glia , vol.53 , pp. 191-200
    • Chen, S.H.1    Gillespie, G.Y.2    Benveniste, E.N.3
  • 29
    • 57649232173 scopus 로고    scopus 로고
    • Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis
    • Cheroni C, Marino M, Tortarolo M, Veglianese P, De Biasi S, Fontana E, et al. Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis. Hum Mol Genet 2009; 18: 82-96.
    • (2009) Hum Mol Genet , vol.18 , pp. 82-96
    • Cheroni, C.1    Marino, M.2    Tortarolo, M.3    Veglianese, P.4    De Biasi, S.5    Fontana, E.6
  • 31
  • 32
    • 35948946893 scopus 로고    scopus 로고
    • Association of the kinesin-binding domain of ranbp2 to kif5b and kif5c determines mitochondria localization and function
    • Cho KI, Cai Y, Yi H, Yeh A, Aslanukov A, Ferreira PA. Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function. Traffic 2007; 8: 1722-35.
    • (2007) Traffic , vol.8 , pp. 1722-1735
    • Cho, K.I.1    Cai, Y.2    Yi, H.3    Yeh, A.4    Aslanukov, A.5    Ferreira, P.A.6
  • 33
    • 0035516124 scopus 로고    scopus 로고
    • From charcot to lou gehrig: Deciphering selective motor neuron death in als
    • Cleveland DW, Rothstein JD. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2001; 2: 806-19.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 35
    • 0032168898 scopus 로고    scopus 로고
    • Regulation of class i mhc gene expression in the developing and mature cns by neural activity
    • Corriveau RA, Huh GS, Shatz CJ. Regulation of class I MHC gene expression in the developing and mature CNS by neural activity. Neuron 1998; 21: 505-20.
    • (1998) Neuron , vol.21 , pp. 505-520
    • Corriveau, R.A.1    Huh, G.S.2    Shatz, C.J.3
  • 37
    • 84865654196 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: New insights into underlying molecular mechanisms and opportunities for therapeutic intervention
    • Cozzolino M, Pesaresi MG, Gerbino V, Grosskreutz J, Carrì MT. Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention. Antioxid Redox Signal 2012; 17: 1277-330.
    • (2012) Antioxid Redox Signal , vol.17 , pp. 1277-1330
    • Cozzolino, M.1    Pesaresi, M.G.2    Gerbino, V.3    Grosskreutz, J.4    Carrì, M.T.5
  • 39
    • 79955824241 scopus 로고    scopus 로고
    • The "dying-back" phenomenon of motor neurons in als
    • Dadon-Nachum M, Melamed E, Offen D. The "dying-back" phenomenon of motor neurons in ALS. J Mol Neurosci 2011; 43: 470-7.
    • (2011) J Mol Neurosci , vol.43 , pp. 470-477
    • Dadon-Nachum, M.1    Melamed, E.2    Offen, D.3
  • 40
    • 79953035505 scopus 로고    scopus 로고
    • Pa28 and the proteasome immunosubunits play a central and independent role in the production of mhc class i-binding peptides in vivo
    • de Graaf N, van Helden MJ, Textoris-Taube K, Chiba T, Topham DJ, Kloetzel PM, et al. PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo. Eur J Immunol 2011; 41: 926-35.
    • (2011) Eur J Immunol , vol.41 , pp. 926-935
    • De Graaf, N.1    Van Helden, M.J.2    Textoris-Taube, K.3    Chiba, T.4    Topham, D.J.5    Kloetzel, P.M.6
  • 41
    • 0032568563 scopus 로고    scopus 로고
    • Nonneuronal isoforms of stop protein are responsible for microtubule cold stability in mammalian fibroblasts
    • Denarier E, Fourest-Lieuvin A, Bosc C, Pirollet F, Chapel A, Margolis RL, et al. Nonneuronal isoforms of STOP protein are responsible for microtubule cold stability in mammalian fibroblasts. Proc Natl Acad Sci USA 1998; 95: 6055-60.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6055-6660
    • Denarier, E.1    Fourest-Lieuvin, A.2    Bosc, C.3    Pirollet, F.4    Chapel, A.5    Margolis, R.L.6
  • 42
    • 35548991459 scopus 로고    scopus 로고
    • Familial amyotrophic lateral sclerosis-linked sod1 mutants perturb fast axonal transport to reduce axonal mitochondria content
    • De Vos KJ, Chapman AL, Tennant ME, Manser C, Tudor EL, Lau KF, et al. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Hum Mol Genet 2007; 16: 2720-8.
    • (2007) Hum Mol Genet , vol.16 , pp. 2720-2708
    • De Vos, K.J.1    Chapman, A.L.2    Tennant, M.E.3    Manser, C.4    Tudor, E.L.5    Lau, K.F.6
  • 45
    • 0034891713 scopus 로고    scopus 로고
    • Uncoupling proteins: Their roles in adaptive thermogenesis and substrate metabolism reconsidered
    • Dulloo AG, Samec S. Uncoupling proteins: their roles in adaptive thermogenesis and substrate metabolism reconsidered. Br J Nutr 2001; 86: 123-39.
    • (2001) Br J Nutr , vol.86 , pp. 123-139
    • Dulloo, A.G.1    Samec, S.2
  • 46
    • 0036081355 scopus 로고    scopus 로고
    • Ncbi gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002; 30: 207-10.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3    Omnibus, G.E.4
  • 47
    • 0034717016 scopus 로고    scopus 로고
    • Human umbilical cord blood effect on sod mice (amyotrophic lateral sclerosis)
    • Ende N, Weinstein F, Chen R, Ende M. Human umbilical cord blood effect on sod mice (amyotrophic lateral sclerosis). Life Sci 2000; 67: 53-9.
    • (2000) Life Sci , vol.67 , pp. 53-59
    • Ende, N.1    Weinstein, F.2    Chen, R.3    Ende, M.4
  • 49
    • 34548157024 scopus 로고    scopus 로고
    • Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the sod1 g93a mouse model of familial als
    • Ferraiuolo L, Heath PR, Holden H, Kasher P, Kirby J, Shaw PJ. Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. J Neurosci 2007; 27: 9201-19.
    • (2007) J Neurosci , vol.27 , pp. 9201-9219
    • Ferraiuolo, L.1    Heath, P.R.2    Holden, H.3    Kasher, P.4    Kirby, J.5    Shaw, P.J.6
  • 52
    • 77949358391 scopus 로고    scopus 로고
    • Major histocompatibility complex class i expression and glial reaction influence spinal motoneuron synaptic plasticity during the course of experimental autoimmune encephalomyelitis
    • Freria CM, Zanon RG, Santos LM, Oliveira AL. Major histocompatibility complex class I expression and glial reaction influence spinal motoneuron synaptic plasticity during the course of experimental autoimmune encephalomyelitis. J Comp Neurol 2010; 518: 990-1007.
    • (2010) J Comp Neurol , vol.518 , pp. 990-1007
    • Freria, C.M.1    Zanon, R.G.2    Santos, L.M.3    Oliveira, A.L.4
  • 55
  • 56
    • 0028125281 scopus 로고
    • Transgenic-mouse model of amyotrophic lateral sclerosis
    • Gurney ME. Transgenic-mouse model of amyotrophic lateral sclerosis. N Engl J Med 1994; 331: 1721-2.
    • (1994) N Engl J Med , vol.331 , pp. 1721-1722
    • Gurney, M.E.1
  • 57
    • 84855296204 scopus 로고    scopus 로고
    • Novel roles of complement in t effector cell regulation
    • Heeger PS, Kemper C. Novel roles of complement in T effector cell regulation. Immunobiology 2012; 217: 216-24.
    • (2012) Immunobiology , vol.217 , pp. 216-224
    • Heeger, P.S.1    Kemper, C.2
  • 59
    • 79951754463 scopus 로고    scopus 로고
    • Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: A window of opportunity in the search for genetic modifiers
    • Heiman-Patterson TD, Sher RB, Blankenhorn EA, Alexander G, Deitch JS, Kunst CB, et al. Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: a window of opportunity in the search for genetic modifiers. Amyotroph Lateral Scler 2011; 12: 79-86.
    • (2011) Amyotroph Lateral Scler , vol.12 , pp. 79-86
    • Heiman-Patterson, T.D.1    Sher, R.B.2    Blankenhorn, E.A.3    Alexander, G.4    Deitch, J.S.5    Kunst, C.B.6
  • 60
    • 10744229158 scopus 로고    scopus 로고
    • Presence of dendritic cells, mcp-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
    • Henkel JS, Engelhardt JI, Sikló s L, Simpson EP, Kim SH, Pan T, et al. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neurol 2004; 55: 221-35.
    • (2004) Ann Neurol , vol.55 , pp. 221-235
    • Henkel, J.S.1    Engelhardt, J.I.2    Siklós, L.3    Simpson, E.P.4    Kim, S.H.5    Pan, T.6
  • 61
    • 33644821966 scopus 로고    scopus 로고
    • The chemokine mcp-1 and the dendritic and myeloid cells it attracts are increased in the msod1 mouse model of als
    • Henkel JS, Beers DR, Sikló s L, Appel SH. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol Cell Neurosci 2006; 31: 427-37.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 427-437
    • Henkel, J.S.1    Beers, D.R.2    Siklós, L.3    Appel, S.H.4
  • 62
    • 79957990024 scopus 로고    scopus 로고
    • Complement upregulation and activation on motor neurons and neuromuscular junction in the sod1 g93a mouse model of familial amyotrophic lateral sclerosis
    • Heurich B, El Idrissi NB, Donev RM, Petri S, Claus P, Neal J, et al. Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis. J Neuroimmunol 2011; 235: 104-9.
    • (2011) J Neuroimmunol , vol.235 , pp. 104-109
    • Heurich, B.1    El Idrissi, N.B.2    Donev, R.M.3    Petri, S.4    Claus, P.5    Neal, J.6
  • 64
    • 0035911254 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific t helper cell type 1 immune response in experimental autoimmune encephalomyelitis
    • Huang DR, Wang J, Kivisakk P, Rollins BJ, Ransohoff RM. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J Exp Med 2001; 193: 713-26.
    • (2001) J Exp Med , vol.193 , pp. 713-726
    • Huang, D.R.1    Wang, J.2    Kivisakk, P.3    Rollins, B.J.4    Ransohoff, R.M.5
  • 65
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using david bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 67
    • 40449103061 scopus 로고    scopus 로고
    • Expression of nonclassical class i major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system
    • Ishii T, Mombaerts P. Expression of nonclassical class I major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system. J Neurosci 2008; 28: 2332-41.
    • (2008) J Neurosci , vol.28 , pp. 2332-2341
    • Ishii, T.1    Mombaerts, P.2
  • 68
    • 39849103473 scopus 로고    scopus 로고
    • Neuronspecific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice
    • Jaarsma D, Teuling E, Haasdijk ED, De Zeeuw CI, Hoogenraad CC. Neuronspecific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. J Neurosci 2008; 28: 2075-88.
    • (2008) J Neurosci , vol.28 , pp. 2075-2088
    • Jaarsma, D.1    Teuling, E.2    Haasdijk, E.D.3    De Zeeuw, C.I.4    Hoogenraad, C.C.5
  • 69
  • 70
    • 79960962456 scopus 로고    scopus 로고
    • Role of snares in membrane fusion
    • Jena BP. Role of SNAREs in membrane fusion. Adv Exp Med Biol 2011; 713: 13-32.
    • (2011) Adv Exp Med Biol , vol.713 , pp. 13-32
    • Jena, B.P.1
  • 71
    • 84865187620 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases
    • Johri A, Beal MF. Mitochondrial dysfunction in neurodegenerative diseases. J Pharmacol Exp Ther 2012; 342: 619-30.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 619-630
    • Johri, A.1    Beal, M.F.2
  • 72
    • 78149434112 scopus 로고    scopus 로고
    • The nrf2 system as a potential target for the development of indirect antioxidants
    • Jung KA, Kwak MK. The Nrf2 system as a potential target for the development of indirect antioxidants. Molecules 2010; 15: 7266-91.
    • (2010) Molecules , vol.15 , pp. 7266-7291
    • Jung, K.A.1    Kwak, M.K.2
  • 73
    • 0037086851 scopus 로고    scopus 로고
    • A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections
    • Jung C, Higgins CM, Xu Z. A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections. J Neurosci Methods 2002a; 114: 165-72.
    • (2002) J Neurosci Methods , vol.114 , pp. 165-172
    • Jung, C.1    Higgins, C.M.2    Xu, Z.3
  • 74
    • 0036830072 scopus 로고    scopus 로고
    • Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis
    • Jung C, Higgins CM, Xu Z. Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis. J Neurochem 2002b; 83: 535-45.
    • (2002) J Neurochem , vol.83 , pp. 535-545
    • Jung, C.1    Higgins, C.M.2    Xu, Z.3
  • 76
    • 77950907407 scopus 로고    scopus 로고
    • Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts
    • Kapeta S, Chondrogianni N, Gonos EASE. Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. J Biol Chem 2010; 285: 8171-84.
    • (2010) J Biol Chem , vol.285 , pp. 8171-8884
    • Kapeta, S.1    Chondrogianni, N.2    Ease, G.3
  • 77
    • 77951699996 scopus 로고    scopus 로고
    • The rad6 dna damage tolerance pathway operates uncoupled from the replication fork and is functional beyond s phase
    • Karras GI, Jentsch S. The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase. Cell 2010; 141: 255-67.
    • (2010) Cell , vol.141 , pp. 255-267
    • Karras, G.I.1    Jentsch, S.2
  • 78
    • 36949019768 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis models and human neuropathology: Similarities and differences
    • Kato S. Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol 2008; 115: 97-114.
    • (2008) Acta Neuropathol , vol.115 , pp. 97-114
    • Kato, S.1
  • 80
    • 21944454604 scopus 로고    scopus 로고
    • Mutant sod1 alters the motor neuronal transcriptome: Implications for familial als
    • Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, et al. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS. Brain 2005; 128: 1686-706.
    • (2005) Brain , vol.128 , pp. 1686-1706
    • Kirby, J.1    Halligan, E.2    Baptista, M.J.3    Allen, S.4    Heath, P.R.5    Holden, H.6
  • 81
    • 54349107187 scopus 로고    scopus 로고
    • Targeting angiogenin in therapy of amyotrophic lateral sclerosis
    • Kishikawa H, Wu D, Hu GF. Targeting angiogenin in therapy of amyotrophic lateral sclerosis. Expert Opin Ther Targets 2008; 12: 1229-42.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 1229-1242
    • Kishikawa, H.1    Wu, D.2    Hu, G.F.3
  • 82
    • 66049093998 scopus 로고    scopus 로고
    • Oncostatin m-induced ccl2 transcription in osteoblastic cells is mediated by multiple levels of stat-1 and stat-3 signaling: An implication for the pathogenesis of arthritis
    • Kok SH, Hong CY, Kuo MY, Wang CC, Hou KL, Lin YT, et al. Oncostatin M-induced CCL2 transcription in osteoblastic cells is mediated by multiple levels of STAT-1 and STAT-3 signaling: an implication for the pathogenesis of arthritis. Arthritis Rheum 2009; 60: 1451-62.
    • (2009) Arthritis Rheum , vol.60 , pp. 1451-1462
    • Kok, S.H.1    Hong, C.Y.2    Kuo, M.Y.3    Wang, C.C.4    Hou, K.L.5    Lin, Y.T.6
  • 83
    • 37749033461 scopus 로고    scopus 로고
    • Drosophila vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation
    • Korolchuk VI, Schutz MM, Gó mez-Llorente C, Rocha J, Lansu NR, Collins SM, et al. Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation. J Cell Sci 2007; 120: 4367-76.
    • (2007) J Cell Sci , vol.120 , pp. 4367-4376
    • Korolchuk, V.I.1    Schutz, M.M.2    Gómez-Llorente, C.3    Rocha, J.4    Lansu, N.R.5    Collins, S.M.6
  • 84
    • 0018407031 scopus 로고
    • Cell-mediated immunity to polio and hla antigens in amyotrophic lateral sclerosis
    • Kott E, Kott E, Livni E, Zamir R, Kuritzky A. Cell-mediated immunity to polio and HLA antigens in amyotrophic lateral sclerosis. Neurology 1979; 29: 1040-4.
    • (1979) Neurology , vol.29 , pp. 1040-1044
    • Kott, E.1    Kott, E.2    Livni, E.3    Zamir, R.4    Kuritzky, A.5
  • 85
    • 0842304134 scopus 로고    scopus 로고
    • Nuclear factor e2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
    • Kraft AD, Johnson DA, Johnson JA. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. J Neurosci 2004; 24: 1101-12.
    • (2004) J Neurosci , vol.24 , pp. 1101-1112
    • Kraft, A.D.1    Johnson, D.A.2    Johnson, J.A.3
  • 86
    • 33748080476 scopus 로고    scopus 로고
    • Neuronal sensitivity to kainic acid is dependent on the nrf2-mediated actions of the antioxidant response element
    • Kraft AD, Lee JM, Johnson DA, Kan YW, Johnson JA. Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element. J Neurochem 2006; 98: 1852-65.
    • (2006) J Neurochem , vol.98 , pp. 1852-1865
    • Kraft, A.D.1    Lee, J.M.2    Johnson, D.A.3    Kan, Y.W.4    Johnson, J.A.5
  • 87
    • 34548287969 scopus 로고    scopus 로고
    • Activation of the nrf2-Are pathway in muscle and spinal cord during als-like pathology in mice expressing mutant sod1
    • Kraft AD, Resch JM, Johnson DA, Johnson JA. Activation of the Nrf2-ARE pathway in muscle and spinal cord during ALS-like pathology in mice expressing mutant SOD1. Exp Neurol 2007; 207: 107-17.
    • (2007) Exp Neurol , vol.207 , pp. 107-117
    • Kraft, A.D.1    Resch, J.M.2    Johnson, D.A.3    Johnson, J.A.4
  • 89
    • 30344446249 scopus 로고    scopus 로고
    • Chemokines in multiple sclerosis: Cxcl12 and cxcl13 up-regulation is differentially linked to cns immune cell recruitment
    • Krumbholz M, Theil D, Cepok S, Hemmer B, Kivisäkk P, Ransohoff RM, et al. Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 2006; 129: 200-11.
    • (2006) Brain , vol.129 , pp. 200-211
    • Krumbholz, M.1    Theil, D.2    Cepok, S.3    Hemmer, B.4    Kivisäkk, P.5    Ransohoff, R.M.6
  • 90
    • 0141621061 scopus 로고    scopus 로고
    • Nf-e2-related factor-2 mediates neuroprotection against mitochondrial complex i inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
    • Lee JM, Shih AY, Murphy TH, Johnson JA. NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. J Biol Chem 2003; 278: 37948-56.
    • (2003) J Biol Chem , vol.278 , pp. 37948-37956
    • Lee, J.M.1    Shih, A.Y.2    Murphy, T.H.3    Johnson, J.A.4
  • 91
    • 79955470830 scopus 로고    scopus 로고
    • Trimming of ubiquitin chains by proteasome-Associated deubiquitinating enzymes
    • 10R110.003871
    • Lee MJ, Lee BH, Hanna J, King RW, Finley D. Trimming of ubiquitin chains by proteasome-Associated deubiquitinating enzymes. Mol Cell Proteomics 2011; 10R110.003871.
    • (2011) Mol Cell Proteomics
    • Lee, M.J.1    Lee, B.H.2    Hanna, J.3    King, R.W.4    Finley, D.5
  • 92
    • 78649940361 scopus 로고    scopus 로고
    • Angiogenin-mediated rrna transcription in cancer and neurodegeneration
    • Li S, Hu GF. Angiogenin-mediated rRNA transcription in cancer and neurodegeneration. Int J Biochem Mol Biol 2010; 1: 26-35.
    • (2010) Int J Biochem Mol Biol , vol.1 , pp. 26-35
    • Li, S.1    Hu, G.F.2
  • 93
    • 0032051640 scopus 로고    scopus 로고
    • Expression of mhc class i and beta2-microglobulin in rat spinal motoneurons: Regulatory influences by ifn-gamma and axotomy
    • Linda H, Hammarberg H, Cullheim S, Levinovitz A, Khademi M, Olsson T. Expression of MHC class I and beta2-microglobulin in rat spinal motoneurons: regulatory influences by IFN-gamma and axotomy. Exp Neurol 1998; 150: 282-95.
    • (1998) Exp Neurol , vol.150 , pp. 282-295
    • Linda, H.1    Hammarberg, H.2    Cullheim, S.3    Levinovitz, A.4    Khademi, M.5    Olsson, T.6
  • 94
    • 33748644662 scopus 로고    scopus 로고
    • Probe-level measurement error improves accuracy in detecting differential gene expression
    • Liu X, Milo M, Lawrence ND, Rattray M. Probe-level measurement error improves accuracy in detecting differential gene expression. Bioinformatics 2006; 22: 2107-13.
    • (2006) Bioinformatics , vol.22 , pp. 2107-2113
    • Liu, X.1    Milo, M.2    Lawrence, N.D.3    Rattray, M.4
  • 95
    • 34249716301 scopus 로고    scopus 로고
    • The dynlt3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, bub3
    • Lo KW, Kogoy JM, Pfister KK. The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3. J Biol Chem 2007; 282: 11205-12.
    • (2007) J Biol Chem , vol.282 , pp. 11205-11212
    • Lo, K.W.1    Kogoy, J.M.2    Pfister, K.K.3
  • 96
    • 34250656185 scopus 로고    scopus 로고
    • Toxicity from different sod1 mutants dysregulates the complement system and the neuronal regenerative response in als motor neurons
    • Lobsiger CS, Boillé e S, Cleveland DW. Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. Proc Natl Acad Sci USA 2007; 104: 7319-26.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7319-7326
    • Lobsiger, C.S.1    Boillée, S.2    Cleveland, D.W.3
  • 97
    • 35549006420 scopus 로고    scopus 로고
    • Glial cells as intrinsic components of noncellautonomous neurodegenerative disease
    • Lobsiger CS, Cleveland DW. Glial cells as intrinsic components of noncellautonomous neurodegenerative disease. Nat Neurosci 2007; 10: 1355-60.
    • (2007) Nat Neurosci , vol.10 , pp. 1355-1360
    • Lobsiger, C.S.1    Cleveland, D.W.2
  • 98
    • 67549139908 scopus 로고    scopus 로고
    • Vesicular trafficking and autophagosome formation
    • Longatti A, Tooze SA. Vesicular trafficking and autophagosome formation. Cell Death Differ 2009; 16: 956-65.
    • (2009) Cell Death Differ , vol.16 , pp. 956-965
    • Longatti, A.1    Tooze, S.A.2
  • 99
    • 66749104344 scopus 로고    scopus 로고
    • Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis
    • Magrané J, Manfredi G. Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis. Antioxid Redox Signal 2009; 11: 1615-26.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1615-1626
    • Magrané, J.1    Manfredi, G.2
  • 100
    • 46749087854 scopus 로고    scopus 로고
    • Complement c3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice
    • Maier M, Peng Y, Jiang L, Seabrook TJ, Carroll MC, Lemere CA. Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice. J Neurosci 2008; 28: 6333-41.
    • (2008) J Neurosci , vol.28 , pp. 6333-6341
    • Maier, M.1    Peng, Y.2    Jiang, L.3    Seabrook, T.J.4    Carroll, M.C.5    Lemere, C.A.6
  • 101
    • 84860382183 scopus 로고    scopus 로고
    • Effect of genetic background on onset and disease progression in the sod1-g93a model of amyotrophic lateral sclerosis
    • Mancuso R, Olivá n S, Mancera P, Pasté n-Zamorano A, Manzano R, Casas C, et al. Effect of genetic background on onset and disease progression in the SOD1-G93A model of amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2012; 13: 302-10.
    • (2012) Amyotroph Lateral Scler , vol.13 , pp. 302-310
    • Mancuso, R.1    Oliván, S.2    Mancera, P.3    Pastén-Zamorano, A.4    Manzano, R.5    Casas, C.6
  • 102
    • 33751237994 scopus 로고    scopus 로고
    • Mechanisms of disease: Astrocytes in neurodegenerative disease
    • Maragakis NJ, Rothstein JD. Mechanisms of disease: astrocytes in neurodegenerative disease. Nat Clin Pract Neurol 2006; 2: 679-89.
    • (2006) Nat Clin Pract Neurol , vol.2 , pp. 679-689
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 104
    • 84878124559 scopus 로고    scopus 로고
    • Pharmacological nrf2-Are pathway activation is protective in mouse and patient fibroblast models of amyotrophic lateral sclerosis
    • Mead RJ, Higginbottom A, Bennett E, Kirby J, Barber SC, Allen SP, et al. Pharmacological NRF2-ARE pathway activation is protective in mouse and patient fibroblast models of amyotrophic lateral sclerosis. Free Radic Biol Med 2013; 61C: 438-452.
    • (2013) Free Radic Biol Med , vol.61 C , pp. 438-452
    • Mead, R.J.1    Higginbottom, A.2    Bennett, E.3    Kirby, J.4    Barber, S.C.5    Allen, S.P.6
  • 105
    • 0034842960 scopus 로고    scopus 로고
    • Transection of major histocompatibility complex class i-induced neurites by cytotoxic t lymphocytes
    • Medana I, Martinic MA, Wekerle H, Neumann H. Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am J Pathol 2001; 159: 809-15.
    • (2001) Am J Pathol , vol.159 , pp. 809-815
    • Medana, I.1    Martinic, M.A.2    Wekerle, H.3    Neumann, H.4
  • 106
    • 3242875557 scopus 로고    scopus 로고
    • Axonal mitochondrial transport and potential are correlated
    • Miller KE, Sheetz MP. Axonal mitochondrial transport and potential are correlated. J Cell Sci 2004; 117: 2791-804.
    • (2004) J Cell Sci , vol.117 , pp. 2791-2804
    • Miller, K.E.1    Sheetz, M.P.2
  • 107
    • 84875443717 scopus 로고    scopus 로고
    • Axonal transport deficits and neurodegenerative diseases
    • Millecamps S, Julien JP. Axonal transport deficits and neurodegenerative diseases. Nat Rev Neurosci 2013; 14: 161-76.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 161-176
    • Millecamps, S.1    Julien, J.P.2
  • 109
    • 67650388103 scopus 로고    scopus 로고
    • A selective inhibitor of the immunoproteasome subunit lmp7 blocks cytokine production and attenuates progression of experimental arthritis
    • Muchamuel T, Basler M, Aujay MA, Suzuki E, Kalim KW, Lauer C, et al. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med 2009; 15: 781-7.
    • (2009) Nat Med , vol.15 , pp. 781-787
    • Muchamuel, T.1    Basler, M.2    Aujay, M.A.3    Suzuki, E.4    Kalim, K.W.5    Lauer, C.6
  • 110
    • 0035076597 scopus 로고    scopus 로고
    • Complement anaphylatoxin c5a neuroprotects through mitogen-Activated protein kinase-dependent inhibition of caspase 3
    • Mukherjee P, Pasinetti GM. Complement anaphylatoxin C5a neuroprotects through mitogen-Activated protein kinase-dependent inhibition of caspase 3. J Neurochem 2001; 77: 43-9.
    • (2001) J Neurochem , vol.77 , pp. 43-49
    • Mukherjee, P.1    Pasinetti, G.M.2
  • 111
    • 39649121460 scopus 로고    scopus 로고
    • Complement anaphylatoxin c5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo
    • Mukherjee P, Thomas S, Pasinetti GM. Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo. J Neuroinflammation 2008; 5: 5.
    • (2008) J Neuroinflammation , vol.5 , pp. 5
    • Mukherjee, P.1    Thomas, S.2    Pasinetti, G.M.3
  • 112
    • 37149006825 scopus 로고    scopus 로고
    • Elevation of mcp-1 and mcp-1/vegf ratio in cerebrospinal fluid of amyotrophic lateral sclerosis patients
    • Nagata T, Nagano I, Shiote M, Narai H, Murakami T, Hayashi T, et al. Elevation of MCP-1 and MCP-1/VEGF ratio in cerebrospinal fluid of amyotrophic lateral sclerosis patients. Neurol Res 2007; 29: 772-6.
    • (2007) Neurol Res , vol.29 , pp. 772-776
    • Nagata, T.1    Nagano, I.2    Shiote, M.3    Narai, H.4    Murakami, T.5    Hayashi, T.6
  • 113
    • 0035897128 scopus 로고    scopus 로고
    • Characterization of two promoters that regulate alternative transcripts in the microtubule-Associated protein (map) 1a gene
    • Nakayama A, Odajima T, Murakami H, Mori N, Takahashi M. Characterization of two promoters that regulate alternative transcripts in the microtubule-Associated protein (MAP) 1A gene. Biochim Biophys Acta 2001; 1518: 260-6.
    • (2001) Biochim Biophys Acta , vol.1518 , pp. 260-266
    • Nakayama, A.1    Odajima, T.2    Murakami, H.3    Mori, N.4    Takahashi, M.5
  • 114
    • 66749144065 scopus 로고    scopus 로고
    • Nitroproteomics of peripheral blood mononuclear cells from patients and a rat model of als
    • Nardo G, Pozzi S, Mantovani S, Garbelli S, Marinou K, Basso M, et al. Nitroproteomics of peripheral blood mononuclear cells from patients and a rat model of ALS. Antioxid Redox Signal 2009; 11: 1559-67.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1559-1567
    • Nardo, G.1    Pozzi, S.2    Mantovani, S.3    Garbelli, S.4    Marinou, K.5    Basso, M.6
  • 115
    • 80053615914 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells
    • Nardo G, Pozzi S, Pignataro M, Lauranzano E, Spano G, Garbelli S, et al. Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells. PLoS One 2011; 6: e25545.
    • (2011) PLoS One , vol.6
    • Nardo, G.1    Pozzi, S.2    Pignataro, M.3    Lauranzano, E.4    Spano, G.5    Garbelli, S.6
  • 116
    • 33845317263 scopus 로고    scopus 로고
    • Did2 coordinates vps4-mediated dissociation of escrt-iii from endosomes
    • Nickerson DP, West M, Odorizzi G. Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes. J Cell Biol 2006; 175: 715-20.
    • (2006) J Cell Biol , vol.175 , pp. 715-720
    • Nickerson, D.P.1    West, M.2    Odorizzi, G.3
  • 117
    • 0035869453 scopus 로고    scopus 로고
    • Neuronal expression of a functional receptor for the c5a complement activation fragment
    • O'Barr SA, Caguioa J, Gruol D, Perkins G, Ember JA, Hugli T, et al. Neuronal expression of a functional receptor for the C5a complement activation fragment. J Immunol 2001; 166: 4154-62.
    • (2001) J Immunol , vol.166 , pp. 4154-4162
    • O'Barr, S.A.1    Caguioa, J.2    Gruol, D.3    Perkins, G.4    Ember, J.A.5    Hugli, T.6
  • 118
    • 11144245674 scopus 로고    scopus 로고
    • A role for mhc class i molecules in synaptic plasticity and regeneration of neurons after axotomy
    • Oliveira AL, Thams S, Lidman O, Piehl F, Hökfelt T, Kärre K, et al. A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy. Proc Natl Acad Sci USA 2004; 101: 17843-8.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17843-17848
    • Oliveira, A.L.1    Thams, S.2    Lidman, O.3    Piehl, F.4    Hökfelt, T.5    Kärre, K.6
  • 119
    • 0033562337 scopus 로고    scopus 로고
    • Complement-derived anaphylatoxin c5a protects against glutamate-mediated neurotoxicity
    • Osaka H, Mukherjee P, Aisen PS, Pasinetti GM. Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity. J Cell Biochem 1999; 73: 303-11.
    • (1999) J Cell Biochem , vol.73 , pp. 303-311
    • Osaka, H.1    Mukherjee, P.2    Aisen, P.S.3    Pasinetti, G.M.4
  • 120
    • 67449164805 scopus 로고    scopus 로고
    • Specificity of cytoplasmic dynein subunits in discrete membrane-Trafficking steps
    • Palmer KJ, Hughes H, Stephens DJ. Specificity of cytoplasmic dynein subunits in discrete membrane-Trafficking steps. Mol Biol Cell 2009; 20: 2885-99.
    • (2009) Mol Biol Cell , vol.20 , pp. 2885-2899
    • Palmer, K.J.1    Hughes, H.2    Stephens, D.J.3
  • 122
    • 33749006845 scopus 로고    scopus 로고
    • Als phenotypes with mutations in chmp2b (charged multivesicular body protein 2b). Mrc proteomics in als study; freja consortium
    • Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, et al. ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). MRC Proteomics in ALS Study; FReJA Consortium. Neurology 2006; 67: 1074-7.
    • (2006) Neurology , vol.67 , pp. 1074-1077
    • Parkinson, N.1    Ince, P.G.2    Smith, M.O.3    Highley, R.4    Skibinski, G.5    Andersen, P.M.6
  • 124
    • 27744542191 scopus 로고    scopus 로고
    • No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model
    • Perrin FE, Boisset G, Docquier M, Schaad O, Descombes P, Kato AC. No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model. Hum Mol Genet 2005; 14: 3309-20.
    • (2005) Hum Mol Genet , vol.14 , pp. 3309-3320
    • Perrin, F.E.1    Boisset, G.2    Docquier, M.3    Schaad, O.4    Descombes, P.5    Kato, A.C.6
  • 125
    • 33748090942 scopus 로고    scopus 로고
    • Cell death pathways differ in several mouse models with motoneurone disease: Analysis of pure motoneurone populations at a presymptomatic age
    • Perrin FE, Boisset G, Lathuiliè re A, Kato AC. Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age. Neurochem 2006; 98: 1959-72.
    • (2006) Neurochem , vol.98 , pp. 1959-1972
    • Perrin, F.E.1    Boisset, G.2    Lathuilière, A.3    Kato, A.C.4
  • 127
    • 78649848069 scopus 로고    scopus 로고
    • The immunoproteasome, the 20s proteasome and the pa28-b proteasome regulator are oxidative-stress-Adaptive proteolytic complexes
    • Pickering AM, Koop AL, Teoh CY, Ermak G, Grune T, Davies KJ. The immunoproteasome, the 20S proteasome and the PA28-b proteasome regulator are oxidative-stress-Adaptive proteolytic complexes. Biochem J 2010; 432: 585-94.
    • (2010) Biochem J , vol.432 , pp. 585-594
    • Pickering, A.M.1    Koop, A.L.2    Teoh, C.Y.3    Ermak, G.4    Grune, T.5    Davies, K.J.6
  • 128
    • 84858972249 scopus 로고    scopus 로고
    • Nrf2-dependent induction of proteasome and pa28-b regulator are required for adaptation to oxidative stress
    • Pickering AM, Linder RA, Zhang H, Forman HJ, Davies KJ. Nrf2-dependent induction of proteasome and Pa28-b regulator are required for adaptation to oxidative stress. J Biol Chem 2012; 287: 10021-31.
    • (2012) J Biol Chem , vol.287 , pp. 10021-10031
    • Pickering, A.M.1    Linder, R.A.2    Zhang, H.3    Forman, H.J.4    Davies, K.J.5
  • 129
    • 68149100027 scopus 로고    scopus 로고
    • Treatment with lithium carbonate does not improve disease progression in two different strains of sod1 mutant mice
    • Pizzasegola C, Caron I, Daleno C, Ronchi A, Minoia C, Carrì MT, et al. Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice. Amyotroph Lateral Scler 2009; 10: 221-8.
    • (2009) Amyotroph Lateral Scler , vol.10 , pp. 221-228
    • Pizzasegola, C.1    Caron, I.2    Daleno, C.3    Ronchi, A.4    Minoia, C.5    Carrì, M.T.6
  • 130
    • 33845713194 scopus 로고    scopus 로고
    • Hrpn13/adrm1/gp110 is a novel proteasome subunit that binds the deubiquitinating enzyme, uch37
    • Qiu XB, Ouyang SY, Li CJ, Miao S, Wang L, Goldberg AL. hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. EMBO J 2006; 25: 5742-53.
    • (2006) EMBO J , vol.25 , pp. 5742-5753
    • Qiu, X.B.1    Ouyang, S.Y.2    Li, C.J.3    Miao, S.4    Wang, L.5    Goldberg, A.L.6
  • 132
    • 0242382637 scopus 로고    scopus 로고
    • Characterisation of pgs1, a subunit of a protein complex co-purifying with tubulin polyglutamylase
    • Regnard C, Fesquet D, Janke C, Boucher D, Desbruyé res E, Koulakoff A, et al. Characterisation of PGs1, a subunit of a protein complex co-purifying with tubulin polyglutamylase. J Cell Sci 2003; 116: 4181-90.
    • (2003) J Cell Sci , vol.116 , pp. 4181-4190
    • Regnard, C.1    Fesquet, D.2    Janke, C.3    Boucher, D.4    Desbruyéres, E.5    Koulakoff, A.6
  • 133
    • 84875441083 scopus 로고    scopus 로고
    • The changing scene of amyotrophic lateral sclerosis
    • Robberecht W, Philips T. The changing scene of amyotrophic lateral sclerosis. Nat Rev Neurosci 2013; 14: 248-64.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 248-264
    • Robberecht, W.1    Philips, T.2
  • 134
    • 26844548098 scopus 로고    scopus 로고
    • The role of the complement system in innate immunity
    • Rus H, Cudrici C, Niculescu F. The role of the complement system in innate immunity. Immunol Res 2005; 33: 103-12.
    • (2005) Immunol Res , vol.33 , pp. 103-112
    • Rus, H.1    Cudrici, C.2    Niculescu, F.3
  • 135
    • 67649650263 scopus 로고    scopus 로고
    • Roles of endosomal trafficking in neurite outgrowth and guidance
    • Sann S, Wang Z, Brown H, Jin Y. Roles of endosomal trafficking in neurite outgrowth and guidance. Trends Cell Biol 2009; 19: 317-24.
    • (2009) Trends Cell Biol , vol.19 , pp. 317-324
    • Sann, S.1    Wang, Z.2    Brown, H.3    Jin, Y.4
  • 136
    • 58149463437 scopus 로고    scopus 로고
    • Synaptic vesicle protein trafficking at the glutamate synapse
    • Santos MS, Li H, Voglmaier SM. Synaptic vesicle protein trafficking at the glutamate synapse. Neuroscience 2009; 158: 189-203.
    • (2009) Neuroscience , vol.158 , pp. 189-203
    • Santos, M.S.1    Li, H.2    Voglmaier, S.M.3
  • 137
    • 0031031971 scopus 로고    scopus 로고
    • Murine monocyte chemoattractant protein (mcp)-5: A novel cc chemokine that is a structural and functional homologue of human mcp-1
    • Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF, Luster AD. Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1. J Exp Med 1997; 185: 99-109.
    • (1997) J Exp Med , vol.185 , pp. 99-109
    • Sarafi, M.N.1    Garcia-Zepeda, E.A.2    MacLean, J.A.3    Charo, I.F.4    Luster, A.D.5
  • 138
    • 58149232639 scopus 로고    scopus 로고
    • Nuclear erythroid 2-related factor 2 antioxidative response element signaling pathway in motor cortex and spinal cord in amyotrophic lateral sclerosis
    • Sarlette A, Krampfl K, Grothe C, Neuhoff N, Dengler R, Petri S. Nuclear erythroid 2-related factor 2 antioxidative response element signaling pathway in motor cortex and spinal cord in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2008; 67: 1055-1062.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 1055-1062
    • Sarlette, A.1    Krampfl, K.2    Grothe, C.3    Neuhoff, N.4    Dengler, R.5    Petri, S.6
  • 139
    • 34249679667 scopus 로고    scopus 로고
    • A thermodynamic ligand binding study of the third pdz domain (pdz3) from the mammalian neuronal protein psd-95
    • Saro D, Li T, Rupasinghe C, Paredes A, Caspers N, Spaller MR. A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95. Biochemistry 2007; 46: 6340-52.
    • (2007) Biochemistry , vol.46 , pp. 6340-6352
    • Saro, D.1    Li, T.2    Rupasinghe, C.3    Paredes, A.4    Caspers, N.5    Spaller, M.R.6
  • 140
    • 67349164383 scopus 로고    scopus 로고
    • A role for motoneuron subtype-selective er stress in disease manifestations of fals mice
    • Saxena S, Cabuy E, Caroni P. A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice. Nat Neurosci 2009; 12: 627-36.
    • (2009) Nat Neurosci , vol.12 , pp. 627-636
    • Saxena, S.1    Cabuy, E.2    Caroni, P.3
  • 141
    • 27644469489 scopus 로고    scopus 로고
    • Mutation of vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse
    • Schmitt-John T, Drepper C, Mussmann A, Hahn P, Kuhlmann M, Thiel C, et al. Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nat Genet 2005; 37: 1213-5.
    • (2005) Nat Genet , vol.37 , pp. 1213-1215
    • Schmitt-John, T.1    Drepper, C.2    Mussmann, A.3    Hahn, P.4    Kuhlmann, M.5    Thiel, C.6
  • 144
    • 46349087273 scopus 로고    scopus 로고
    • Uncoupling protein-2 (ucp2) induces mitochondrial proton leak and increases susceptibility of non-Alcoholic steatohepatitis (nash) liver to ischaemia-reperfusion injury
    • Serviddio G, Bellanti F, Tamborra R, Rollo T, Capitanio N, Romano AD, et al. Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-Alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury. Gut 2008; 57: 957-65.
    • (2008) Gut , vol.57 , pp. 957-965
    • Serviddio, G.1    Bellanti, F.2    Tamborra, R.3    Rollo, T.4    Capitanio, N.5    Romano, A.D.6
  • 145
    • 70349792000 scopus 로고    scopus 로고
    • Mhc class i: An unexpected role in neuronal plasticity
    • Shatz CJ. MHC class I: an unexpected role in neuronal plasticity. Neuron 2009; 64: 40-5.
    • (2009) Neuron , vol.64 , pp. 40-45
    • Shatz, C.J.1
  • 146
    • 71849118179 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in amyotrophic lateral sclerosis
    • Shi P, Gal J, Kwinter DM, Liu X, Zhu H. Mitochondrial dysfunction in amyotrophic lateral sclerosis. Biochim Biophys Acta 2010; 1802: 45-51.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 45-51
    • Shi, P.1    Gal, J.2    Kwinter, D.M.3    Liu, X.4    Zhu, H.5
  • 147
    • 0037996661 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione biosynthesis and release by nrf2-expressing glia potently protects neurons from oxidative stress
    • Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, et al. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci 2003; 23: 3394-406.
    • (2003) J Neurosci , vol.23 , pp. 3394-3406
    • Shih, A.Y.1    Johnson, D.A.2    Wong, G.3    Kraft, A.D.4    Jiang, L.5    Erb, H.6
  • 148
    • 72849120050 scopus 로고    scopus 로고
    • Complementderived anaphylatoxin c3a regulates in vitro differentiation and migration of neural progenitor cells
    • Shinjyo N, Sta hlberg A, Dragunow M, Pekny M, Pekna M. Complementderived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells. Stem Cells 2009; 27: 2824-32.
    • (2009) Stem Cells , vol.27 , pp. 2824-2832
    • Shinjyo, N.1    Stahlberg, A.2    Dragunow, M.3    Pekny, M.4    Pekna, M.5
  • 151
    • 0345822598 scopus 로고    scopus 로고
    • The positive false discovery rate: A bayesian interpretation and the q-value
    • Storey JD. The positive false discovery rate: a Bayesian interpretation and the q-value. Ann Statist 2006; 31: 2013-35.
    • (2006) Ann Statist , vol.31 , pp. 2013-2035
    • Storey, J.D.1
  • 152
    • 33746863745 scopus 로고    scopus 로고
    • Intrathecal upregulation of granulocyte colony stimulating factor and its neuroprotective actions on motor neurons in amyotrophic lateral sclerosis
    • Tanaka M, Kikuchi H, Ishizu T, Minohara M, Osoegawa M, Motomura K, et al. Intrathecal upregulation of granulocyte colony stimulating factor and its neuroprotective actions on motor neurons in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2006; 65: 816-25.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 816-825
    • Tanaka, M.1    Kikuchi, H.2    Ishizu, T.3    Minohara, M.4    Osoegawa, M.5    Motomura, K.6
  • 153
    • 33646095177 scopus 로고    scopus 로고
    • Jnk1 phosphorylation of scg10 determines microtubule dynamics and axodendritic length
    • Tararuk T, Ostman N, Li W, Björkblom B, Padzik A, Zdrojewska J, et al. JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length. J Cell Biol 2006; 173: 265-77.
    • (2006) J Cell Biol , vol.173 , pp. 265-277
    • Tararuk, T.1    Ostman, N.2    Li, W.3    Björkblom, B.4    Padzik, A.5    Zdrojewska, J.6
  • 155
    • 34848904785 scopus 로고    scopus 로고
    • Motor neuron disease-Associated mutant vesicle-Associated membrane protein-Associated protein (vap) b recruits wild-Type vaps into endoplasmic reticulum-derived tubular aggregates
    • Teuling E, Ahmed S, Haasdijk E, Demmers J, Steinmetz MO, Akhmanova A, et al. Motor neuron disease-Associated mutant vesicle-Associated membrane protein-Associated protein (VAP) B recruits wild-Type VAPs into endoplasmic reticulum-derived tubular aggregates. J Neurosci 2007; 27: 9801-15.
    • (2007) J Neurosci , vol.27 , pp. 9801-9815
    • Teuling, E.1    Ahmed, S.2    Haasdijk, E.3    Demmers, J.4    Steinmetz, M.O.5    Akhmanova, A.6
  • 156
    • 70350555276 scopus 로고    scopus 로고
    • Classical major histocompatibility complex class i molecules in motoneurons: New actors at the neuromuscular junction
    • Thams S, Brodin P, Plantman S, Saxelin R, Kärre K, Cullheim S. Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction. J Neurosci 2009; 29: 13503-15.
    • (2009) J Neurosci , vol.29 , pp. 13503-13515
    • Thams, S.1    Brodin, P.2    Plantman, S.3    Saxelin, R.4    Kärre, K.5    Cullheim, S.6
  • 157
    • 0033880688 scopus 로고    scopus 로고
    • Expression of a complete and functional complement system by human neuronal cells in vitro
    • Thomas A, Gasque P, Vaudry D, Gonzalez B, Fontaine M. Expression of a complete and functional complement system by human neuronal cells in vitro. Int Immunol 2000; 12: 1015-23.
    • (2000) Int Immunol , vol.12 , pp. 1015-1023
    • Thomas, A.1    Gasque, P.2    Vaudry, D.3    Gonzalez, B.4    Fontaine, M.5
  • 159
    • 0030842642 scopus 로고    scopus 로고
    • Complement and glutamate neurotoxicity. Genotypic influences of c5 in a mouse model of hippocampal neurodegeneration
    • Tocco G, Musleh W, Sakhi S, Schreiber SS, Baudry M, Pasinetti GM. Complement and glutamate neurotoxicity. Genotypic influences of C5 in a mouse model of hippocampal neurodegeneration. Mol Chem Neuropathol 1997; 31: 289-300.
    • (1997) Mol Chem Neuropathol , vol.31 , pp. 289-300
    • Tocco, G.1    Musleh, W.2    Sakhi, S.3    Schreiber, S.S.4    Baudry, M.5    Pasinetti, G.M.6
  • 160
    • 3142651352 scopus 로고    scopus 로고
    • Mitogen-Activated protein kinases erk1/2 and p38 are required for maximal regulation of timp-1 by oncostatin m in murine fibroblasts
    • Tong L, Smyth D, Kerr C, Catterall J, Richards CD. Mitogen-Activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts. Cell Signal 2004; 16: 1123-32.
    • (2004) Cell Signal , vol.16 , pp. 1123-1132
    • Tong, L.1    Smyth, D.2    Kerr, C.3    Catterall, J.4    Richards, C.D.5
  • 161
    • 0033956898 scopus 로고    scopus 로고
    • Activating transcription factor 3 (atf3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury
    • Tsujino H, Kondo E, Fukuoka T, Dai Y, Tokunaga A, Miki K, et al. Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: a novel neuronal marker of nerve injury. Mol Cell Neurosci 2000; 15: 170-82.
    • (2000) Mol Cell Neurosci , vol.15 , pp. 170-182
    • Tsujino, H.1    Kondo, E.2    Fukuoka, T.3    Dai, Y.4    Tokunaga, A.5    Miki, K.6
  • 162
    • 42249102078 scopus 로고    scopus 로고
    • Transgenics, toxicity and therapeutics in rodent models of mutant sod1-mediated familial als
    • Turner BJ, Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Prog Neurobiol 2008; 85: 94-134.
    • (2008) Prog Neurobiol , vol.85 , pp. 94-134
    • Turner, B.J.1    Talbot, K.2
  • 163
    • 0035847643 scopus 로고    scopus 로고
    • Complement anaphylatoxin c3a is selectively protective against nmda-induced neuronal cell death
    • Van Beek J, Nicole O, Ali C, Ischenko A, MacKenzie ET, Buisson A, et al. Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death. Neuroreport 2001; 12: 289-93.
    • (2001) Neuroreport , vol.12 , pp. 289-293
    • Van Beek, J.1    Nicole, O.2    Ali, C.3    Ischenko, A.4    MacKenzie, E.T.5    Buisson, A.6
  • 164
    • 84868656581 scopus 로고    scopus 로고
    • Epha4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
    • Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, et al. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med 2012; 18: 1418-22.
    • (2012) Nat Med , vol.18 , pp. 1418-1422
    • Van Hoecke, A.1    Schoonaert, L.2    Lemmens, R.3    Timmers, M.4    Staats, K.A.5    Laird, A.S.6
  • 165
    • 58149379610 scopus 로고    scopus 로고
    • Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis
    • Vargas MR, Johnson DA, Sirkis DW, Messing A, Johnson JA. Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci 2008; 28: 13574-81.
    • (2008) J Neurosci , vol.28 , pp. 13574-13581
    • Vargas, M.R.1    Johnson, D.A.2    Sirkis, D.W.3    Messing, A.4    Johnson, J.A.5
  • 166
    • 27644485845 scopus 로고    scopus 로고
    • Atf3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-sod1 transgenic mice and correlates with c-jun phosphorylation, chop expression, somato-dendritic ubiquitination and golgi fragmentation
    • Vlug AS, Teuling E, Haasdijk ED, French P, Hoogenraad CC, Jaarsma D. ATF3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-SOD1 transgenic mice and correlates with c-Jun phosphorylation, CHOP expression, somato-dendritic ubiquitination and Golgi fragmentation. Eur J Neurosci 2005; 22: 1881-94.
    • (2005) Eur J Neurosci , vol.22 , pp. 1881-1894
    • Vlug, A.S.1    Teuling, E.2    Haasdijk, E.D.3    French, P.4    Hoogenraad, C.C.5    Jaarsma, D.6
  • 167
    • 0034775793 scopus 로고    scopus 로고
    • Oncostatin m in the anti-inflammatory response
    • Wahl AF, Wallace PM. Oncostatin M in the anti-inflammatory response. Ann Rheum Dis 2001; 60 (Suppl 3): iii75-80.
    • (2001) Ann Rheum Dis , vol.60 , Issue.SUPPL. 3
    • Wahl, A.F.1    Wallace, P.M.2
  • 168
    • 0026585611 scopus 로고
    • Intracellular compartmentation structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: The 'phosphocreatine circuit' for cellular energy homeostasis
    • Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HM. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem J 1992; 281: 21-40.
    • (1992) Biochem J , vol.281 , pp. 21-40
    • Wallimann, T.1    Wyss, M.2    Brdiczka, D.3    Nicolay, K.4    Eppenberger, H.M.5
  • 170
    • 0034658342 scopus 로고    scopus 로고
    • Erratum
    • Erratum in: J Immunol 2000; 164: 5531.
    • (2000) J Immunol , vol.164 , pp. 5531
  • 171
    • 23644462114 scopus 로고    scopus 로고
    • The gp130 ligand oncostatin m regulates tissue inhibitor of metalloproteinases-1 through erk1/2 and p38 in human adult cardiac myocytes and in human adult cardiac fibroblasts: A possible role for the gp130/gp130 ligand system in the modulation of extracellular matrix degradation in the human heart
    • Weiss TW, Kvakan H, Kaun C, Zorn G, Speidl WS, Pfaffenberger S, et al. The gp130 ligand oncostatin M regulates tissue inhibitor of metalloproteinases-1 through ERK1/2 and p38 in human adult cardiac myocytes and in human adult cardiac fibroblasts: a possible role for the gp130/gp130 ligand system in the modulation of extracellular matrix degradation in the human heart. J Mol Cell Cardiol 2005; 39: 545-551.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 545-551
    • Weiss, T.W.1    Kvakan, H.2    Kaun, C.3    Zorn, G.4    Speidl, W.S.5    Pfaffenberger, S.6
  • 172
    • 33845671189 scopus 로고    scopus 로고
    • Oncostatin m is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo
    • Weiss TW, Samson AL, Niego B, Daniel PB, Medcalf RL. Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo. FASEB J 2006; 20: 2369-71.
    • (2006) FASEB J , vol.20 , pp. 2369-2371
    • Weiss, T.W.1    Samson, A.L.2    Niego, B.3    Daniel, P.B.4    Medcalf, R.L.5
  • 175
    • 76349084466 scopus 로고    scopus 로고
    • Complement in neuroprotection and neurodegeneration
    • Yanamadala V, Friedlander RM. Complement in neuroprotection and neurodegeneration. Trends Mol Med 2010; 16: 69-76.
    • (2010) Trends Mol Med , vol.16 , pp. 69-76
    • Yanamadala, V.1    Friedlander, R.M.2
  • 176
    • 33748188085 scopus 로고    scopus 로고
    • Proteasome recruitment and activation of the uch37 deubiquitinating enzyme by adrm1
    • Yao T, Song L, Xu W, DeMartino GN, Florens L, Swanson SK, et al. Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. Nat Cell Biol 2006; 8: 994-1002.
    • (2006) Nat Cell Biol , vol.8 , pp. 994-1002
    • Yao, T.1    Song, L.2    Xu, W.3    DeMartino, G.N.4    Florens, L.5    Swanson, S.K.6
  • 177
    • 0034661923 scopus 로고    scopus 로고
    • Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis
    • Yepes M, Sandkvist M, Wong MK, Coleman TA, Smith E, Cohan SL, et al. Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis. Blood 2000; 96: 569-76.
    • (2000) Blood , vol.96 , pp. 569-576
    • Yepes, M.1    Sandkvist, M.2    Wong, M.K.3    Coleman, T.A.4    Smith, E.5    Cohan, S.L.6
  • 178
    • 0034703191 scopus 로고    scopus 로고
    • In vitro induction of neuronal apoptosis by anti-fas antibody-containing sera from amyotrophic lateral sclerosis patients
    • Yi FH, Lautrette C, Vermot-Desroches C, Bordessoule D, Couratier P, Wijdenes J, et al. In vitro induction of neuronal apoptosis by anti-Fas antibody-containing sera from amyotrophic lateral sclerosis patients. J Neuroimmunol 2000; 109: 211-20.
    • (2000) J Neuroimmunol , vol.109 , pp. 211-220
    • Yi, F.H.1    Lautrette, C.2    Vermot-Desroches, C.3    Bordessoule, D.4    Couratier, P.5    Wijdenes, J.6
  • 179
    • 0036184052 scopus 로고    scopus 로고
    • Constitutive expression of proinflammatory complement components by subsets of neurons in the central nervous system
    • Yu JX, Bradt BM, Cooper NR. Constitutive expression of proinflammatory complement components by subsets of neurons in the central nervous system. J Neuroimmunol 2002; 123: 91-101.
    • (2002) J Neuroimmunol , vol.123 , pp. 91-101
    • Yu, J.X.1    Bradt, B.M.2    Cooper, N.R.3
  • 180
  • 181
    • 0035257013 scopus 로고    scopus 로고
    • Rab proteins as membrane organizers
    • Zerial M, McBride H. Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2001; 2: 107-17.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 107-117
    • Zerial, M.1    McBride, H.2
  • 182
    • 41149097086 scopus 로고    scopus 로고
    • Als-causing sod1 mutants generate vascular changes prior to motor neuron degeneration
    • Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, et al. ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat Neurosci 2008; 11: 420-2.
    • (2008) Nat Neurosci , vol.11 , pp. 420-422
    • Zhong, Z.1    Deane, R.2    Ali, Z.3    Parisi, M.4    Shapovalov, Y.5    O'Banion, M.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.