Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination

Gene

Volumn 285, Issue 1-2, 2002, Pages 183-191

  Ashley, Carolyn ^a   Pastushok, Landon ^a   McKenna, Sean ^b   Ellison, Michael J ^b   Xiao, Wei ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Error free DNA repair; MMS2; UBC; Ubiquitin conjugating E2 enzyme variant

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA; ENZYME VARIANT; LYSINE; THIOESTER; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; EUKARYOTE; GENETIC COMPLEMENTATION; GENETIC CONSERVATION; GENETIC STABILITY; IN VITRO STUDY; MOLECULAR CLONING; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TWO HYBRID SYSTEM; YEAST;

AMINO ACID SEQUENCE; ANIMALS; DNA REPAIR; DNA REPLICATION; DNA, COMPLEMENTARY; EVOLUTION, MOLECULAR; GENE EXPRESSION; GENETIC COMPLEMENTATION TEST; HUMANS; LIGASES; LYSINE; MALE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PROTEIN BINDING; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES;

ANIMALIA; EUKARYOTA; MAMMALIA;

EID: 0037138391     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00409-2     Document Type: Article

References (35)

1. Analyzing protein-protein interactions using two-hybrid system
2. MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway
3. UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae
4. A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
5. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
6. Lambda YES: A multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations
7. Epitope-tagged ubiquitin. A new probe for analyzing ubiquitin function
8. Ubiquitination
9. Molecular cloning and functional characterization of two murine cDNAs which encode Ubc variants involved in DNA repair and mutagenesis
10. DMSO-enhanced whole cell yeast transformation
11. Ubiquitin-dependent protein degradation
12. The tail of a ubiquitin-conjugating enzyme redirects multi-ubiquitin chain synthesis from the lysine 48-linked configuration to a novel non-lysine-linked form
13. Non-canonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
14. In vitro assembly and recognition of lys-63 polyubiquitin chains
15. The ubiquitin-conjugation system
16. TSG101 may be the prototype of a class of dominant negative ubiquitin regulators
17. Substrate targeting in the ubiquitin system
18. Tsg101: A novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells
19. Up-regulation of CIR1/CROC1 expression upon cell immortalization and in tumor-derived human cell lines
20. Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
21. The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes
22. Bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog
23. Functional and physical characterization of the cell cycle ubiquitin-conjugating enzyme CDC34 (UBC3). Identification of a functional determinant within the tail that facilitates CDC34 self-association
24. CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter
25. Role of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells
26. Mutations altering synaptic connectivity between identified neurons in Drosophila
27. The ubiquitin system
28. A homolog of CROC-1 in a ciliated protist (Sterkiella histriomuscorum) testifies to the ancient origin of the ubiquitin-conjugating enzyme variant family
29. TAK1 is a ubiquitin-dependent kinase of MKK and IKK
30. Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2
31. The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family
32. Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae
33. The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways
34. Cloning and expression of cDNA encoding a human ubiquitin-conjugating enzyme similar to the Drosophila bendless gene product