Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury

Gut

Volumn 57, Issue 7, 2008, Pages 957-965

  Serviddio, Gaetano ^a,b   Bellanti, F ^a   Tamborra, R ^a   Rollo, T ^c   Capitanio, N ^a   Romano, A D ^a   Sastre, J ^b   Vendemiale, G ^c   Altomare, E ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

^b UNIVERSITY OF VALENCIA   (Spain)

^c CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; GLUTATHIONE; HYDROGEN PEROXIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; LIVER CIRRHOSIS; LIVER ISCHEMIA; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL MEMBRANE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTON TRANSPORT; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACUTE DISEASE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ADULT; ALDEHYDES; ANIMALS; DISEASE PROGRESSION; FATTY LIVER; FEMALE; HUMANS; ION CHANNELS; LIVER; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MIDDLE AGED; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 46349087273     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2007.147496     Document Type: Article

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