Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

Brain

Volumn 134, Issue 5, 2011, Pages 1293-1314

  Beers, David R ^a   Henkel, Jenny S ^a   Zhao, Weihua ^a   Wang, Jinghong ^a   Huang, Ailing ^a   Wen, Shixiang ^a   Liao, Bing ^a   Appel, Stanley H ^a  

^a HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

FoxP3; IL 4; inflammation; microglia; regulatory T lymphocytes

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; INTERLEUKIN 4; TRANSCRIPTION FACTOR FOXP3;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL SURVIVAL; CELL TRANSFER; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE COURSE; DISEASE DURATION; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; LIFE EXPECTANCY; MAJOR CLINICAL STUDY; MALE; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; WILD TYPE;

ADULT; AGE FACTORS; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD4; BETA-N-ACETYLHEXOSAMINIDASES; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA-BINDING PROTEINS; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LECTINS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MIDDLE AGED; MUTATION; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SPINAL CORD; SUPEROXIDE DISMUTASE; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTOR 2;

EID: 79957528028     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr074     Document Type: Article

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